Items where Author is "Searcey, Mark"

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Article

Cartwright, Oliver Charles, Beekman, Andrew Michael, Cominetti, Marco M D, Russell, David A and Searcey, Mark (2020) A peptide-duocarmycin conjugate targeting the Thomsen-Friedenreich antigen has potent and selective antitumour activity. Bioconjugate Chemistry, 31 (7). 1745–1749. ISSN 1043-1802

Beekman, Andrew, Cominetti, Marco, Cartwright, Oliver, Boger, Dale L. and Searcey, Mark (2019) A small molecule drug conjugate (SMDC) of DUPA and a duocarmycin built on the solid phase. MedChemComm, 10 (12). pp. 2170-2174. ISSN 2040-2503

Beekman, Andrew M., Cominetti, Marco M. D., Walpole, Samuel J., Prabhu, Saurabh, O'Connell, Maria A., Angulo Alvarez, Jesus and Searcey, Mark (2019) Identification of selective protein-protein interaction inhibitors using efficient in silico peptide-directed ligand design. Chemical Science, 10 (16). pp. 4502-4508. ISSN 2041-6520

Williams, Morwen, Bertrand, Benoît, Hughes, David L., Waller, Zoe Ann Ella, Schmidt, Claudia, Ott, Ingo, O'Connell, Maria Anne, Searcey, Mark and Bochmann, Manfred (2018) Cyclometallated Au(III) dithiocarbamate complexes: synthesis, anticancer evaluation and mechanistic studies. Metallomics, 10 (11). pp. 1655-1666. ISSN 1756-5901

Williams, Morwen RM, Bertrand, Benoît, Fernandez-Cestau, Julio, Waller, Zoë AE, O'Connell, Maria A, Searcey, Mark and Bochmann, Manfred (2018) Acridine-decorated cyclometallated gold(III) complexes: synthesis and anti-tumour investigations. Dalton Transactions, 47 (38). pp. 13523-13534. ISSN 1477-9226

Steel, Richard J., O'Connell, Maria A. and Searcey, Mark (2018) Perfluoroarene-based peptide macrocycles that inhibit the Nrf2/Keap1 interaction. Bioorganic & Medicinal Chemistry Letters, 28 (16). pp. 2728-2731. ISSN 0960-894X

Williams, Morwen, Green, Adam I, Fernandez-Cestau, Julio, Hughes, David L, O'Connell, Maria Anne, Searcey, Mark, Bertrand, Benoit and Bochmann, Manfred (2017) (C^Npz^C)AuIII complexes of acyclic carbene ligands: synthesis and anticancer properties. Dalton Transactions, 46 (39). 13397–13408. ISSN 1477-9226

Bertrand, Benoît, Fernandez-Cestau, Julio, Angulo, Jesus, Cominetti, Marco M.D., Waller, Zoe A.E., Searcey, Mark, O'Connell, Maria A. and Bochmann, Manfred (2017) Cytotoxicity of Pyrazine-Based Cyclometalated (C^Npz^C)Au(III) Carbene Complexes: Impact of the Nature of the Ancillary Ligand on the Biological Properties. Inorganic Chemistry, 56 (10). 5728–5740. ISSN 0020-1669

Austin, Michael J., Hearnshaw, Stephen J., Mitchenall, Lesley A., McDermott, Paul J., Howell, Lesley A., Maxwell, Anthony and Searcey, Mark (2016) A natural product inspired fragment-based approach towards the development of novel anti-bacterial agents. MedChemComm, 7 (7). pp. 1387-1391. ISSN 2040-2503

Angulo, Jesus, Goffin, Sarah, Gandhi, Daivik, Searcey, Mark and Howell, Lesley (2016) Unveiling the "Three Finger Pharmacophore" required for p53-MDM2 Inhibition by Saturation Transfer Difference NMR Initial Growth Rates Approach. Chemistry - A European Journal, 22 (17). pp. 5858-5862. ISSN 0947-6539

Cominetti, Marco, Goffin, Sarah, Raffel, Ewan, Turner, Kerrie, Ramoutar, Jordann, O'Connell, Maria, Howell, Lesley and Searcey, Mark (2015) Identification of a new p53/MDM2 inhibitor motif inspired by studies of chlorofusin. Bioorganic & Medicinal Chemistry Letters, 25 (21). pp. 4878-4880. ISSN 0960-894X

Stephenson, Michael, Howell, Lesley, O'Connell, Maria, Fox, Keith R., Adcock, Claire, Kingston, Jenny, Sheldrake, Helen, Pors, Klaus, Collingwood, Stephen P. and Searcey, Mark (2015) Solid-phase synthesis of duocarmycin analogues and the effect of C-terminal substitution on biological activity. The Journal of Organic Chemistry, 80 (19). 9454–9467. ISSN 0022-3263

Vinader, Victoria, Sadiq, Maria, Sutherland, Mark, Huang, Menying, Loadman, Paul, Elsalem, Lina, Shnyder, Steven, Cui, Hongjuan, Afarinkia, Kamyar, Searcey, Mark, Patterson, Laurence and Pors, Klaus (2015) Probing cytochrome P450-mediated activation with a truncated azinomycin analogue. MedChemComm, 6. pp. 187-191. ISSN 2040-2511

Waller, Zoë A E, Howell, Lesley A, Macdonald, Colin J, O'Connell, Maria A and Searcey, Mark (2014) Identification and characterisation of a G-quadruplex forming sequence in the promoter region of nuclear factor (erythroid-derived 2)-like 2 (Nrf2). Biochemical and Biophysical Research Communications, 447 (1). pp. 128-32. ISSN 0006-291X

Sheldrake, Helen M., Travica, Sandra, Johansson, Inger, Loadman, Paul M., Sutherland, Mark, Elsalem, Lina, Illingworth, Nicola, Cresswell, Alexander J., Reuillon, Tristan, Shnyder, Steven D., Mkrtchian, Souren, Searcey, Mark, Ingelman-Sundberg, Magnus, Patterson, Laurence H. and Pors, Klaus (2013) Re-engineering of the Duocarmycin Structural Architecture Enables Bioprecursor Development Targeting CYP1A1 and CYP2W1 for Biological Activity. Journal of Medicinal Chemistry, 56 (15). pp. 6273-6277. ISSN 0022-2623

Marin, MJ, Rackham, Benjamin D., Round, Andrew N., Howell, Lesley A., Russell, David A. and Searcey, Mark (2013) A rapid screen for molecules that form duplex to duplex crosslinks in DNA. Chemical Communications, 49 (80). p. 9113. ISSN 1359-7345

Rackham, Benjamin D., Howell, Lesley A., Round, Andrew N. and Searcey, Mark (2013) Non-covalent duplex to duplex crosslinking of DNA in solution revealed by single molecule force spectroscopy. Organic & Biomolecular Chemistry, 11 (48). pp. 8340-8347. ISSN 1477-0520

Sutherland, Mark, Gill, Jason H, Loadman, Paul M, Laye, Jonathan P, Sheldrake, Helen M, Illingworth, Nicola A, Alandas, Mohammed N, Cooper, Patricia A, Searcey, Mark, Pors, Klaus, Shnyder, Steve D and Patterson, Laurence H (2013) Antitumor activity of a duocarmycin analogue rationalized to be metabolically activated by cytochrome P450 1A1 in human transitional cell carcinoma of the bladder. Molecular Cancer Therapeutics, 12 (1). pp. 27-37. ISSN 1538-8514

Howell, Lesley A., Bowater, Richard A., O'Connell, Maria A., Reszka, Anthony P., Neidle, Stephen and Searcey, Mark (2012) Synthesis of Small Molecules Targeting Multiple DNA Structures using Click Chemistry. ChemMedChem, 7 (5). pp. 792-804. ISSN 1860-7179

Steel, Richard, Cowan, Jonathan, Payerne, Estelle, O'Connell, Maria A. and Searcey, Mark (2012) Anti-inflammatory effect of a cell penetrating peptide targeting the Nrf2/Keap1 interaction. ACS Medicinal Chemistry Letters, 3 (5). pp. 407-410. ISSN 1948-5875

Howe, J. D., Payerne, E., Woon, E. C. Y., Marfo, S. A., Searcey, M. and Gavrilovic, J. (2011) Screening novel small molecules for effects on cancer cell migration. International Journal of Experimental Pathology, 92 (3). A27. ISSN 0959-9673

Howell, LA, Waller, Z.A.E., Bowater, RP, O'Connell, M and Searcey, M (2011) A small molecule that induces assembly of a four way DNA junction at low temperature. Chemical Communications, 47 (29). pp. 8262-8264. ISSN 1359-7345

Pors, Klaus, Loadman, Paul M., Shnyder, Steven D., Sutherland, Mark, Sheldrake, Helen M., Guino, Meritxell, Kiakos, Konstantinos, Hartley, John A., Searcey, Mark and Patterson, Laurence H. (2011) Modification of the duocarmycin pharmacophore enables CYP1A1 targeting for biological activity. Chemical Communications, 47 (44). pp. 12062-12064. ISSN 1359-7345

Howell, Lesley, Gulam, Rosul, Mueller, Anja, O'Connell, Maria and Searcey, Mark (2010) Design and synthesis of threading intercalators to target DNA. Bioorganic & Medicinal Chemistry Letters, 1 (20). pp. 6956-6959. ISSN 1464-3405

Collingwood, S., Lock, R. and Searcey, Mark (2009) Optimizing drugs for local delivery. Drug News & Perspectives, 22 (10). pp. 627-634. ISSN 0214-0934

Howell, Lesley and Searcey, Mark (2009) Targeting Higher-Order DNA: Beyond the G-Quadruplex. ChemBioChem, 10 (13). pp. 2139-2143. ISSN 1439-7633

Howell, Lesley, Howman, Aaron, O'Connell, Maria, Mueller, Anja and Searcey, Mark (2009) Synthesis and evaluation of 9-aminoacridines derived from benzyne click chemistry. Bioorganic & Medicinal Chemistry Letters, 19 (20). pp. 5880-5883. ISSN 1464-3405

Watanabe, Kenji, Hotta, Kinya, Praseuth, Alex P., Searcey, Mark, Wang, Clay C. C., Oguri, Hiroki and Oikawa, Hideaki (2009) Rationally Engineered Total Biosynthesis of a Synthetic Analogue of a Natural Quinomycin Depsipeptide in Escherichia coli. ChemBioChem, 10 (12). pp. 1965-1968. ISSN 1439-7633

Clark, Ryan C., Lee, Sang Yeul, Hwang, Inkyu, Searcey, Mark and Boger, Dale L. (2009) Evaluation of chlorofusin, its seven chromophore diastereomers, and key analogues. Tetrahedron Letters, 50 (26). pp. 3151-3153.

Shaginian, Alex, Whitby, Landon R., Hong, Sukwon, Hwang, Inkyu, Farooqi, Bilal, Searcey, Mark, Chen, Jiandong, Vogt, Peter K. and Boger, Dale L. (2009) Design, synthesis, and evaluation of an a-helix mimetic library targeting protein-protein interactions. Journal of the American Chemical Society, 131 (15). pp. 5564-5572.

Clark, Ryan C., Lee, Sang Yeul, Searcey, Mark and Boger, Dale L. (2009) The isolation, total synthesis and structure elucidation of chlorofusin, a natural product inhibitor of the p53–MDM2 protein–protein interaction. Natural Product Reports, 26 (4). p. 465.

Dawson, S., Searcey, M., Hampshire, A., Fox, K. and Malkinson, J. (2009) Solid-phase-based synthesis and biological evaluation of novel chromophore analogues of the bis-intercalator TANDEM. Biopolymers, 92 (4). p. 367. ISSN 0006-3525

Ghosh, N., Sheldrake, H. M., Searcey, M. and Pors, K. (2009) Chemical and Biological Explorations of the Family of CC-1065 and the Duocarmycin Natural Products. Current Topics in Medicinal Chemistry, 9 (16). pp. 1494-1524. ISSN 1568-0266

Howell, L. A. and Searcey, Mark (2009) Targeting the Holliday junction: Design and synthesis of acridine-3/4-carboxamide analogs using click chemistry. Abstracts of Papers of the American Chemical Society, 238. 210-ORGN. ISSN 0065-7727

Hampshire, Andrew J., Rusling, David A., Bryan, Stephanie, Paumier, David, Dawson, Simon J., Malkinson, John P., Searcey, Mark and Fox, Keith R. (2008) DNA Binding by Analogues of the Bifunctional Intercalator TANDEM. Biochemistry, 47 (30). pp. 7900-7906.

Armer, Richard E., Cowley, Phillip and Searcey, Mark (2008) Recent disclosures of clinical drug candidates. Drug News & Perspectives, 21 (3). pp. 183-188. ISSN 0214-0934

Dawson, S. J., Malkinson, J. P., Searcey, M. and Gibbons, S. (2008) ORGN 96-Solid-phase-based synthesis and biological evaluation of quinoxaline antibiotics and structural analogs. Abstracts of Papers of the American Chemical Society, 235. 96-ORGN. ISSN 0065-7727

Race, A. D., Pors, K., Shnyder, S. D., Cooper, T. C., Sheldrake, H. M., Searcey, M., Patterson, L. H. and Loadman, P. M. (2008) CYP1A1 activation and pharmacokinetics of a novel chloromethylpyrrollolindoline with potential as a tumour selective prodrug. Ejc Supplements, 6 (12). p. 105. ISSN 1359-6349

Sturla, Shana J., Irwin, John J., Loeppky, Richard N., Mulvihill, Mark J. and Searcey, Marc (2007) Chemistry in cancer research: A vital partnership. Cancer Research, 67 (14). pp. 6539-6543. ISSN 0008-5472

Brogden, Anna L., Hopcroft, Nicholas H., Searcey, Mark and Cardin, Christina J. (2007) Ligand bridging of the DNA Holliday junction: Molecular recognition of a stacked-X four-way junction by a small molecule. Angewandte Chemie-International Edition, 46 (21). pp. 3850-3854. ISSN 1433-7851

Dawson, Simon, Malkinson, John P., Paumier, David and Searcey, Mark (2007) Bisintercalator natural products with potential therapeutic applications: isolation, structure determination, synthetic and biological studies. Natural Product Reports, 24 (1). pp. 109-126. ISSN 0265-0568

Woon, Esther C. Y., Arcieri, Mariangela, Wilderspin, Andrew F., Malkinson, John P. and Searcey, Mark (2007) Solid-phase synthesis of chlorofusin analogues. Journal of Organic Chemistry, 72 (14). pp. 5146-5151. ISSN 0022-3263

David-Cordonnier, Marie‐Hélène, Casely-Hayford, Maxwell, Kouach, Mostafa, Briand, Gilbert, Patterson, Laurence H., Bailly, Christian and Searcey, Mark (2006) Stereoselectivity, sequence specificity and mechanism of action of the azinomycin epoxide. ChemBioChem, 7 (11). 1658–1661. ISSN 1439-4227

Germain, A. R., Porco, J. A., Searcey, M. and Woon, E. (2006) Studies towards the synthesis of the p53-MDM2 inhibitor chlorofusin. Abstracts of Papers of the American Chemical Society, 231. 449-ORGN. ISSN 0065-7727

Guino, M., Patterson, L. H. and Searcey, M. (2006) ORGN 741-Total synthesis of duocarmycin prodrugs. Abstracts of Papers of the American Chemical Society, 232. 741-ORGN. ISSN 0065-7727

Hopcroft, N. H., Brogden, A. L., Searcey, M. and Cardin, C. J. (2006) X-ray crystallographic study of DNA duplex cross-linking: simultaneous binding to two d(CGTACG)(2) molecules by a bis(9-aminoacridine-4-carboxamide) derivative. Nucleic Acids Research, 34 (22). pp. 6663-6672. ISSN 0305-1048

Moore, Michael J. B., Cuenca, Francisco, Searcey, Mark and Neidle, Stephen (2006) Synthesis of distamycin A polyamides targeting G-quadruplex DNA. Organic & Biomolecular Chemistry, 4 (18). pp. 3479-3488. ISSN 1477-0520

Paumier, D., Malkinson, J. P., Hampshire, A. J., Fox, K. R. and Searcey, M. (2006) ORGN 223-Solid phase-supported synthesis of a water-soluble TANDEM analog. Abstracts of Papers of the American Chemical Society, 232. ISSN 0065-7727

Pors, Klaus, Shnyder, Steven D., Teesdale-Spittle, Paul H., Hartley, John A., Zloh, Mire, Searcey, Mark and Patterson, Laurence H. (2006) Synthesis of DNA-directed pyrrolidinyl and piperidinyl confined alkylating chloroalkylaminoanthraquinones: Potential for development of tumor-selective N-oxides. Journal of Medicinal Chemistry, 49 (24). pp. 7013-7023. ISSN 0022-2623

Tsoukala, G., Falconer, R. A. and Searcey, M. (2006) ORGN 731-Toward the total synthesis of Ipomoeassin B. Abstracts of Papers of the American Chemical Society, 232. 731-ORGN. ISSN 0065-7727

Williams, Robert, Searcey, Mark and Potter, Barry (2006) Cancer treatments for the new millennium. Drug News & Perspectives, 19 (4). pp. 229-232. ISSN 0214-0934

Woon, E. C. Y. and Searcey, M. (2006) ORGN 224-Analogs of chlorofusin as potential inhibitors of p53/MDM2 interaction. Abstracts of Papers of the American Chemical Society, 232. 224-ORGN. ISSN 0065-7727

Casely-Hayford, M. A., Kerr, N. O, Smith, E., Gibbons, S. and Searcey, M. (2005) Antitumour antibiotics with potent activity against multidrug resistant (MDR) Staphylococcus aureus: a new approach to targeting resistant bacteria. Med Chem, 1 (6). pp. 619-627. ISSN 1573-4064

Casely-Hayford, M. A., Pors, K., Patterson, L. H., Gerner, C., Neidle, S. and Searcey, M. (2005) Truncated azinomycin analogues intercalate into DNA. Bioorganic & Medicinal Chemistry Letters, 15 (3). pp. 653-656. ISSN 0960-894X

Casely-Hayford, M. A., Pors, K., Patterson, L. H. and Searcey, M. (2005) Design, synthesis and biological evaluation of potential anticancer agents based on the azinomycins. Abstracts of Papers of the American Chemical Society, 229. ISSN 0065-7727

Casely-Hayford, Maxwell A., Pors, Klaus, James, Colin H., Patterson, Laurence H., Hartley, John A. and Searcey, Mark (2005) Design and synthesis of a DNA-crosslinking azinomycin analogue. Organic & Biomolecular Chemistry, 3 (19). pp. 3585-3589. ISSN 1477-0520

David-Cordonnier, M. H., Casely-Hayford, M., Patterson, L. H., Bailly, C. and Searcey, M. (2005) Influence of the stereoisomeric position of azinomycin epoxide on DNA binding and sequence selectivity. Clinical Cancer Research, 11 (24). 9013S-9013S. ISSN 1078-0432

Kerr, N. O., Grewel, S. S., Martin, B. G. O., Karu, K., Patterson, L. H. and Searcey, M. (2005) Design and synthesis of bio-oxidatively activated prodrugs based upon the duocarmycins: Routes to Boc-CI and CI-MI prodrugs. Abstracts of Papers of the American Chemical Society, 229. 413-MEDI. ISSN 0065-7727

Malkinson, J. P., Anim, M. K., Zloh, M., Searcey, M., Hampshire, A. J. and Fox, K. R. (2005) Efficient solid-phase-based total synthesis of the bisintercalator TANDEM. Journal of Organic Chemistry, 70 (19). pp. 7654-7661. ISSN 0022-3263

Pors, Klaus, Plumb, Jane A., Brown, Robert, Teesdale-Spittle, Paul, Searcey, Mark, Smith, Paul J. and Patterson, Laurence H. (2005) Development of nonsymmetrical 1,4-disubstituted anthraquinones that are potently active against cisplatin-resistant ovarian cancer cells. Journal of Medicinal Chemistry, 48 (21). pp. 6690-6695. ISSN 0022-2623

Searcey, M., Karu, K., Grewal, S. S., Kerr, N. O., Griffith, W. and Patterson, L. H. (2005) Prodrug analogs of the duocarmycins activated by CYP-oxidation. Abstracts of Papers of the American Chemical Society, 229. 414-MEDI. ISSN 0065-7727

Searcey, M and Patterson, LH (2004) Resistance in cancer: A target for drug discovery. Current Medicinal Chemistry - Anti-Cancer Agents, 4 (5). pp. 457-460. ISSN 1568-0118

Malkinson, J. P. and Searcey, M. (2003) Solid-phase synthesis of des-N-tetramethyltriostin a (TANDEM). Biopolymers, 71 (3). P280. ISSN 0006-3525

Malkinson, John P., Zloh, Mire, Kadom, Mohanad, Errington, Rachel, Smith, Paul J. and Searcey, Mark (2003) Solid-phase synthesis of the cyclic peptide portion of chlorofusin, an inhibitor of p53-MDM2 interactions. Organic Letters, 5 (26). pp. 5051-5054. ISSN 1523-7060

Searcey, M., Malkinson, J. P. and Kadom, M. (2003) Towards the total synthesis of chlorofusin: Solid phase synthesis of the cyclic peptide. Abstracts of Papers of the American Chemical Society, 226. 708-ORGN. ISSN 0065-7727

Searcey, Mark, Grewal, Sukhwant S., Madeo, Fiorenza and Tsoungas, Petros G. (2003) A mild procedure for the production of secondary amines from oximes and benzisoxazoles. Tetrahedron Letters, 44 (35). pp. 6745-6747. ISSN 0040-4039

Searcey, M. (2002) Duocarmycins - Natures prodrugs? Current Pharmaceutical Design, 8 (15). pp. 1375-1389. ISSN 1381-6128

Tsoungas, Petros G. and Searcey, Mark (2001) A convenient access to benzo-substituted phthalazines as potential precursors to DNA intercalators. Tetrahedron Letters, 42 (37). pp. 6589-6592. ISSN 0040-4039

Boger, D. L., Santillan, A., Searcey, M., Brunette, S. R., Wolkenberg, S. E., Hedrick, M. P. and Jin, Q. (2000) Synthesis and evaluation of 1,2,8,8a-tetrahydrocyclopropa c pyrrolo 3,2-e indol-4(5H)-one, the parent alkylation subunit of CC-1065 and the duocarmycins: Impact of the alkylation subunit substituents and its implications for DNA alkylation catalysis. Journal of Organic Chemistry, 65 (13). pp. 4101-4111. ISSN 0022-3263

Boger, D. L., Searcey, M., Tse, W. C. and Jin, Q. (2000) Bifunctional alkylating agents derived from duocarmycin SA: Potent antitumor activity with altered sequence selectivity. Bioorganic & Medicinal Chemistry Letters, 10 (5). pp. 495-498. ISSN 0960-894X

Boger, Dale L., Aquila, Brian M., Tse, Winston C. and Searcey, Mark (2000) Synthesis and evaluation of a novel bleomycin A(2) analogue: continuing assessment of the linker domain. Tetrahedron Letters, 41 (49). pp. 9493-9498. ISSN 0040-4039

McClean, S, Costelloe, C, Denny, W A, Searcey, Mark and Wakelin, L P (1999) Sequence selectivity, cross-linking efficiency and cytotoxicity of DNA-targeted 4-anilinoquinoline aniline mustards. Anti-Cancer Drug Design, 14 (3). pp. 187-204. ISSN 0266-9536

Boger, Dale L., Ledeboer, Mark W., Kume, Masaharu, Searcey, Mark and Jin, Qing (1999) Total synthesis and comparative evaluation of luzopeptin A-C and quinoxapeptin A-C. Journal of the American Chemical Society, 121 (49). pp. 11375-11383. ISSN 0002-7863

Searcey, Mark, McClean, S, Madden, B, McGown, A T and Wakelin, L P (1998) Synthesis, DNA-cleaving properties and cytotoxicity of intercalating chelidamic acid derivatives. Anti-Cancer Drug Design, 13 (8). pp. 837-855. ISSN 0266-9536

Gallacher, Gerard, Jackson, Caroline S., Searcey, Mark, Goel, Rajiv, Mellor, Geoffrey W., Smith, Carmen Z. and Brocklehurst, Keith (1993) Catalytic antibody activity elicited by active immunisation. Evidence for natural variation involving preferential stabilization of the transition state. European Journal of Biochemistry, 214 (1). pp. 197-207. ISSN 0014-2956

Gallacher, G, Searcey, Mark, Jackson, C S and Brocklehurst, K (1992) Polyclonal antibody-catalysed amide hydrolysis. Biochemical Journal, 284 (3). pp. 675-860. ISSN 0264-6021

Gallacher, G, Jackson, C S, Searcey, Mark, Badman, G T, Goel, R, Topham, C M, Mellor, G W and Brocklehurst, K (1991) A polyclonal antibody preparation with Michaelian catalytic properties. Biochemical Journal, 279 (3). pp. 871-881. ISSN 0264-6021

Gallacher, Gerard, Jackson, Caroline S., Topham, Christopher M., Searcey, Mark, Turner, Benjamin C., Badman, Geoffrey T. and Brocklehurst, Keith (1990) Polyclonal-antibody-catalysed hydrolysis of an aryl nitrophenyl carbonate. Biochemical Society Transactions, 18 (4). pp. 600-601. ISSN 0300-5127

Book Section

Beekman, Andrew, Cominetti, Marco M D and Searcey, Mark (2019) Duocarmycins as Antibody–Drug Conjugate (ADC) Payloads. In: Cytotoxic Payloads for Antibody-Drug Conjugates. Royal Society of Chemistry. ISBN 978-1-78801-077-1

Casely-Hayford, Maxwell and Searcey, Mark (2002) The Azinomycins. Discovery, Synthesis and DNA-Binding Studies. In: DNA and RNA Binders. Wiley, pp. 676-696. ISBN 3527305955

This list was generated on Thu Aug 6 01:34:05 2020 BST.