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Goddard, Zoë Rachael 
ORCID: https://orcid.org/0000-0002-7900-1553, Marin, Maria J. ORCID: https://orcid.org/0000-0001-8021-5498, Russell, David A. and Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949
(2020)
Active targeting of gold nanoparticles as cancer therapeutics.
Chemical Society Reviews, 49 (23).
pp. 8774-8789.
ISSN 0306-0012
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Abstract
Gold nanoparticles (AuNPs) are of increasing interest for their unique properties and their biocompatability, minimal toxicity, multivalency and size tunability makes them exciting drug carriers. The functionalisaton of AuNPs with targeting moieties allows for their selective delivery to cancers, with antibodies, proteins, peptides, aptamers, carbohydrates and small molecules all exploited. Here, we review the recent advances in targeted-AuNPs for the treatment of cancer, with a particular focus on these classes of targeting ligands. We highlight the benefits and potential drawbacks of each ligand class and propose directions in which the field could grow.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being |
| Faculty \ School: | Faculty of Science > School of Pharmacy Faculty of Science > School of Chemistry |
| UEA Research Groups: | Faculty of Medicine and Health Sciences > Research Centres > Norwich Institute for Healthy Aging Faculty of Science > Research Groups > Chemical Biology and Medicinal Chemistry (former - to 2021) |
| Related URLs: | |
| Depositing User: | LivePure Connector |
| Date Deposited: | 20 Oct 2020 23:57 |
| Last Modified: | 21 Apr 2023 00:49 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/77372 |
| DOI: | 10.1039/d0cs01121e |
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