Tsoungas, Petros G. and Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949
(2001)
A convenient access to benzo-substituted phthalazines as potential precursors to DNA intercalators.
Tetrahedron Letters, 42 (37).
pp. 6589-6592.
ISSN 0040-4039
Abstract
2-Nitro-5-methoxybenzaldehyde is converted to amines 2 and 7 via two alternative routes. Upon diazotisation and Sandmeyer reaction, halides 4 and 9 are formed, which, through lithiation and formylation lead to the o-phthalaldehyde. Further cyclisation with hydrazine gives the 5-methoxy-substituted phthalazine. (C) 2001 Elsevier Science Ltd. All rights reserved.
Item Type: | Article |
---|---|
Uncontrolled Keywords: | agents,nitrite,conversion,aryl halides |
Faculty \ School: | Faculty of Science > School of Pharmacy |
Depositing User: | Rachel Smith |
Date Deposited: | 13 Jun 2011 14:31 |
Last Modified: | 24 Oct 2022 03:47 |
URI: | https://ueaeprints.uea.ac.uk/id/eprint/32128 |
DOI: | 10.1016/S0040-4039(01)01302-8 |
Actions (login required)
![]() |
View Item |