Howell, Lesley, Howman, Aaron, O'Connell, Maria ORCID: https://orcid.org/0000-0002-0267-0951, Mueller, Anja
ORCID: https://orcid.org/0000-0003-0774-0434 and Searcey, Mark
ORCID: https://orcid.org/0000-0003-2273-8949
(2009)
Synthesis and evaluation of 9-aminoacridines derived from benzyne click chemistry.
Bioorganic & Medicinal Chemistry Letters, 19 (20).
pp. 5880-5883.
ISSN 1464-3405
Abstract
A small set of 9-aminoacridine-3- and 4-carboxamides were synthesized efficiently using the benzyne/azide click chemistry. The products bind to duplex DNA but have different antitumour activity in the HL60 cell line.
Item Type: | Article |
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Faculty \ School: | Faculty of Science > School of Pharmacy |
Depositing User: | Rachel Smith |
Date Deposited: | 17 Mar 2011 10:58 |
Last Modified: | 12 Jan 2023 13:30 |
URI: | https://ueaeprints.uea.ac.uk/id/eprint/26453 |
DOI: | 10.1016/j.bmcl.2009.08.070 |
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