Items where Author is "Carding, Simon"

Published

Jones, Emily J., Skinner, Benjamin M., Parker, Aimee, Baldwin, Lydia R., Greenman, John, Carding, Simon R. and Funnell, Simon G. P. (2024) An in vitro multi-organ microphysiological system (MPS) to investigate the gut-to-brain translocation of neurotoxins. Biomicrofluidics, 18 (5). ISSN 1932-1058

Jones, Emily J., Stentz, Regis, Parker, Aimée and Carding, Simon R. (2024) Assessing In Vivo Bacterial Extracellular Vesicle (BEV) Biodistribution Using Fluorescent Lipophilic Membrane Stains. In: Bacterial Extracellular Vesicles: Methods and Protocols. Methods in Molecular Biology . Humana Press Inc, pp. 239-251. ISBN 978-1-0716-4057-9

Sommerfelt, Kristian, Schei, Trude, Seton, Katharine A. and Carding, Simon R. (2024) Assessing functional capacity in myalgic encephalopathy/chronic fatigue syndrome: A patient-informed questionnaire. Journal of Clinical Medicine, 13 (12). ISSN 2077-0383

Cook, Ryan, Telatin, Andrea, Hsieh, Shen Yuan, Newberry, Fiona, Tariq, Mohammad A., Baker, Dave J., Carding, Simon R. and Adriaenssens, Evelien M. (2024) Nanopore and Illumina sequencing reveal different viral populations from human gut samples. Microbial Genomics, 10 (4). ISSN 2057-5858

Juodeikis, Rokas, Martins, Carlo, Saalbach, Gerhard, Richardson, Jake, Koev, Todor ORCID: https://orcid.org/0000-0002-8218-9753, Baker, Dave J., Defernez, Marianne, Warren, Martin ORCID: https://orcid.org/0000-0002-6028-6456 and Carding, Simon R. (2024) Differential temporal release and lipoprotein loading in B. thetaiotaomicron bacterial extracellular vesicles. Journal of Extracellular Vesicles, 13 (1). ISSN 2001-3078

Hsieh, Shen Yuan, Savva, George M., Telatin, Andrea, Tiwari, Sumeet K., Tariq, Mohammad A., Newberry, Fiona, Seton, Katharine A., Booth, Catherine, Bansal, Amolak S., Wileman, Thomas, Adriaenssens, Evelien M. and Carding, Simon R. (2023) Investigating the human intestinal DNA virome and predicting disease-associated virus–host interactions in severe myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). International Journal of Molecular Sciences, 24 (24). ISSN 1661-6596

Seton, Katharine A., Defernez, Marianne, Telatin, Andrea, Tiwari, Sumeet K., Savva, George M., Hayhoe, Antonietta, Noble, Alistair, de Carvalho-KoK, Ana L. S., James, Steve A., Bansal, Amolak, Wileman, Thomas and Carding, Simon R. (2023) Investigating antibody reactivity to the intestinal microbiome in severe myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): A feasibility study. International Journal of Molecular Sciences, 24 (20). ISSN 1661-6596

Baldwin, Lydia, Jones, Emily J., Iles, Alexander, Carding, Simon R., Pamme, Nicole, Dyer, Charlotte E. and Greenman, John (2023) Development of a dual-flow tissue perfusion device for modeling the gastrointestinal tract-brain axis. Biomicrofluidics, 17 (5). ISSN 1932-1058

James, Steve A., Parker, Aimee, Purse, Catherine, Telatin, Andrea, Baker, David, Evans, Rhiannon, Holmes, Sandy, Funnell, Simon G. P. and Carding, Simon R. (2023) Draft genome sequence of a primate isolate of Kazachstania pintolopesii. Mycopathologia, 188 (5). pp. 821-823. ISSN 0301-486X

Stentz, Régis, Cheema, Jitender, Philo, Mark and Carding, Simon R. (2023) A possible aquatic origin of the Thiaminase TenA of the human gut symbiont Bacteroides thetaiotaomicron. Journal of Molecular Evolution, 91 (4). pp. 482-491. ISSN 0022-2844

James, Steve A., Telatin, Andrea, Baker, David, Evans, Rhiannon, Clarke, Paul ORCID: https://orcid.org/0000-0001-6203-7632, Hall, Lindsay J. ORCID: https://orcid.org/0000-0001-8938-5709 and Carding, Simon R. (2023) Draft genome sequence of a preterm infant-derived isolate of Candida parapsilosis. Microbiology Resource Announcements, 12 (3). ISSN 2576-098X

Phillips, Sarah, Watt, Rachel, Atkinson, Thomas, Rajan, Shelina, Hayhoe, Antonietta, Savva, George M., Hornberger, Michael ORCID: https://orcid.org/0000-0002-2214-3788, Burton, Ben J. L., Saada, Janak, Cambell-Kelly, Melissa, Rushbrook, Simon and Carding, Simon R. (2022) A protocol paper for the MOTION Study—A longitudinal study in a cohort aged 60 years and older to obtain mechanistic knowledge of the role of the gut microbiome during normal healthy ageing in order to develop strategies that will improve lifelong health and wellbeing. PLoS One, 17 (11). ISSN 1932-6203

Fonseca, Sonia, Carvalho, Ana L., Miquel-Clopés, Ariadna, Jones, Emily J., Juodeikis, Rokas, Stentz, Régis and Carding, Simon R. (2022) Extracellular vesicles produced by the human gut commensal bacterium Bacteroides thetaiotaomicron elicit anti-inflammatory responses from innate immune cells. Frontiers in Microbiology, 13. ISSN 1664-302X

Noble, Alistair, Pring, Edward T., Durant, Lydia, Man, Ripple, Dilke, Stella M., Hoyles, Lesley, James, Steve A., Carding, Simon R., Jenkins, John T. and Knight, Stella C. (2022) Altered immunity to microbiota, B cell activation and depleted γδ/resident memory T cells in colorectal cancer. Cancer Immunology, Immunotherapy, 71 (11). 2619–2629. ISSN 0340-7004

Wang, Yingxue, Ramos, Maria ORCID: https://orcid.org/0000-0002-6758-4069, Jefferson, Matthew, Zhang, Weijiao, Beraza, Naiara, Carding, Simon, Powell, Penny P. ORCID: https://orcid.org/0000-0002-5347-0490, Stewart, James P., Mayer, Ulrike ORCID: https://orcid.org/0000-0003-2328-0052 and Wileman, Thomas (2022) Control of infection by LC3-associated phagocytosis, CASM, and detection of raised vacuolar pH by the V-ATPase-ATG16L1 axis. Science Advances, 8 (43). ISSN 2375-2548

James, Steve A., Parker, Aimee, Purse, Catherine, Telatin, Andrea, Baker, David, Holmes, Sandy, Durham, James, Funnell, Simon G. P. and Carding, Simon R. (2022) The cynomolgus macaque intestinal mycobiome is dominated by the Kazachstania genus and K. pintolopesii species. Journal of Fungi, 8 (10). ISSN 2309-608X

Jordan, Anne, Carding, Simon R and Hall, Lindsay J ORCID: https://orcid.org/0000-0001-8938-5709 (2022) The early-life gut microbiome and vaccine efficacy. The Lancet Microbe, 3 (10). E787-E794. ISSN 2666-5247

Stentz, Régis, Jones, Emily, Juodeikis, Rokas, Wegmann, Udo, Guirro, Maria, Goldson, Andrew J., Brion, Arlaine, Booth, Catherine, Sudhakar, Padhmanand, Brown, Ian R., Korcsmáros, Tamás and Carding, Simon R. (2022) The proteome of extracellular vesicles produced by the human gut bacteria Bacteroides thetaiotaomicron in vivo is influenced by environmental and host-derived factors. Applied and Environmental Microbiology, 88 (16). ISSN 0099-2240

Parker, Aimée, James, Steve A., Purse, Catherine, Brion, Arlaine, Goldson, Andrew, Telatin, Andrea, Baker, David and Carding, Simon R. (2022) Absence of bacteria permits fungal gut-to-brain translocation and invasion in germfree mice but ageing alone does not drive pathobiont expansion in conventionally raised mice. Frontiers in Aging Neuroscience, 14. ISSN 1663-4365

Noble, Alistair, Durant, Lydia, Dilke, Stella M., Man, Ripple, Martin, Isabel, Patel, Roshani, Hoyles, Lesley, Pring, Edward T., Latchford, Andrew, Clark, Susan K., Carding, Simon R. and Knight, Stella C. (2022) Altered mucosal immune-microbiota interactions in familial adenomatous polyposis. Clinical and Translational Gastroenterology, 13 (7). ISSN 2155-384X

Parker, Aimée, Romano, Stefano, Ansorge, Rebecca, Aboelnour, Asmaa, Le Gall, Gwenaelle ORCID: https://orcid.org/0000-0002-1379-2196, Savva, George M., Pontifex, Matthew G. ORCID: https://orcid.org/0000-0003-2174-2313, Telatin, Andrea, Baker, David, Jones, Emily, Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756, Rudder, Steven, Blackshaw, L. Ashley, Jeffery, Glen and Carding, Simon R. (2022) Fecal microbiota transfer between young and aged mice reverses hallmarks of the aging gut, eye, and brain. Microbiome, 10. ISSN 2049-2618

Brooks-Warburton, Johanne, Modos, Dezso, Sudhakar, Padhmanand, Madgwick, Matthew, Thomas, John P., Bohar, Balazs, Fazekas, David, Zoufir, Azedine, Kapuy, Orsolya, Szalay-Beko, Mate, Verstockt, Bram, Hall, Lindsay J. ORCID: https://orcid.org/0000-0001-8938-5709, Watson, Alastair ORCID: https://orcid.org/0000-0003-3326-0426, Tremelling, Mark, Parkes, Miles, Vermeire, Severine, Bender, Andreas, Carding, Simon R. and Korcsmaros, Tamas (2022) A systems genomics approach to uncover patient-specific pathogenic pathways and proteins in ulcerative colitis. Nature Communications, 13 (1). ISSN 2041-1723

Gul, Lejla, Modos, Dezso, Fonseca, Sonia, Madgwick, Matthew, Thomas, John P., Sudhakar, Padhmanand, Booth, Catherine, Stentz, Régis, Carding, Simon R. and Korcsmaros, Tamas (2022) Extracellular vesicles produced by the human commensal gut bacterium Bacteroides thetaiotaomicron affect host immune pathways in a cell-type specific manner that are altered in inflammatory bowel disease. Journal of Extracellular Vesicles, 11 (1). ISSN 2001-3078

Hoyles, Lesley, Pontifex, Matthew G. ORCID: https://orcid.org/0000-0003-2174-2313, Rodriguez-Ramiro, Ildefonso, Anis-Alavi, M. Areeb, Jelane, Khadija S., Snelling, Tom, Solito, Egle, Fonseca, Sonia, Carvalho, Ana L., Carding, Simon R., Müller, Michael ORCID: https://orcid.org/0000-0002-5930-9905, Glen, Robert C., Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756 and McArthur, Simon (2021) Regulation of blood–brain barrier integrity by microbiome-associated methylamines and cognition by trimethylamine N-oxide. Microbiome, 9 (1). ISSN 2049-2618

Stentz, Régis, Miquel-Clopés, Ariadna and Carding, Simon R. (2021) Production, Isolation, and Characterization of Bioengineered Bacterial Extracellular Membrane Vesicles Derived from Bacteroides thetaiotaomicron and Their Use in Vaccine Development. In: Bacterial Vaccines: Methods and Protocols. Methods in Molecular Biology . Humana Press Inc, pp. 171-190. ISBN 978-1-0716-1902-5

Hsieh, Shen-Yuan, Tariq, Mohammad A., Telatin, Andrea, Ansorge, Rebecca, Adriaenssens, Evelien M., Savva, George M., Booth, Catherine, Wileman, Tom, Hoyles, Lesley and Carding, Simon R. (2021) Comparison of PCR versus PCR-Free DNA library preparation for characterising the human faecal virome. Viruses-Basel, 13 (10). ISSN 1999-4915

Jones, Emily, Stentz, Régis, Telatin, Andrea, Savva, George M., Booth, Catherine, Baker, David, Rudder, Steven, Knight, Stella C., Noble, Alistair and Carding, Simon R. (2021) The origin of plasma-derived bacterial extracellular vesicles in healthy individuals and patients with inflammatory bowel disease: A pilot study. Genes, 12 (10). ISSN 2073-4425

Tariq, Mohammad A. and Carding, Simon R. (2021) Complete genome sequence of a Bacteroides fragilis bacteriophage, vB_BfrS_NCTC. Microbiology Resource Announcements, 10 (29).

Wang, Yingxue, Sharma, Parul, Jefferson, Matthew, Zhang, Weijiao, Bone, Ben, Kipar, Anja, Bitto, David, Coombes, Janine L., Pearson, Timothy, Man, Angela, Zhekova, Alex, Bao, Yongping ORCID: https://orcid.org/0000-0002-6425-0370, Tripp, Ralph A., Carding, Simon R., Yamauchi, Yohei, Mayer, Ulrike ORCID: https://orcid.org/0000-0003-2328-0052, Powell, Penny P. ORCID: https://orcid.org/0000-0002-5347-0490, Stewart, James P. and Wileman, Thomas (2021) Non‐canonical autophagy functions of ATG16L1 in epithelial cells limit lethal infection by influenza A virus. The EMBO Journal, 40 (6). ISSN 0261-4189

Serramito-Gómez, Inmaculada, Boada-Romero, Emilio, Villamuera, Raquel, Fernández-Cabrera, Álvaro, Cedillo, José Luis, Martín-Regalado, Ángela, Carding, Simon, Mayer, Uli ORCID: https://orcid.org/0000-0003-2328-0052, Powell, Penny P. ORCID: https://orcid.org/0000-0002-5347-0490, Wileman, Thomas, García-Higuera, Irene and Pimentel-Muiños, Felipe X. (2020) Regulation of cytokine signaling through direct interaction between cytokine receptors and the ATG16L1 WD40 domain. Nature Communications, 11 (1). ISSN 2041-1723

James, Stephen A., Phillips, Sarah, Telatin, Andrea, Baker, David, Ansorge, Rebecca, Clarke, Paul ORCID: https://orcid.org/0000-0001-6203-7632, Hall, Lindsay J. ORCID: https://orcid.org/0000-0001-8938-5709 and Carding, Simon R. (2020) Preterm infants harbour a rapidly changing mycobiota that includes Candida pathobionts. Journal of Fungi, 6 (4). ISSN 2309-608X

Modasia, Amisha, Parker, Aimee, Jones, Emily, Stentz, Regis, Brion, Arlaine, Goldson, Andrew, Defernez, Marianne, Wileman, Tom, Blackshaw, L. Ashley and Carding, Simon R. (2020) Regulation of enteroendocrine cell networks by the major human gut symbiont Bacteroides thetaiotaomicron. Frontiers in Microbiology, 11. ISSN 1664-302X

Aktar, Rubina, Parkar, Nabil, Stentz, Regis, Baumard, Lucas, Parker, Aimee, Goldson, Andrew, Brion, Arlaine, Carding, Simon, Blackshaw, Ashley and Peiris, Madusha (2020) Human resident gut microbe Bacteroides thetaiotaomicron regulates colonic neuronal innervation and neurogenic function. Gut Microbes, 11 (6). pp. 1745-1757. ISSN 1949-0976

Tariq, Mohammad A., Newberry, Fiona, Haagmans, Rik, Booth, Catherine, Wileman, Tom, Hoyles, Lesley, Clokie, Martha R. J., Ebdon, James and Carding, Simon R. (2020) Genome characterization of a novel wastewater Bacteroides fragilis bacteriophage (vB_BfrS_23) and its host GB124. Frontiers in Microbiology, 11. ISSN 1664-302X

Heckmann, Bradlee L., Teubner, Brett J. W., Boada-Romero, Emilio, Tummers, Bart, Guy, Clifford, Fitzgerald, Patrick, Mayer, Ulrike ORCID: https://orcid.org/0000-0003-2328-0052, Carding, Simon, Zakharenko, Stanislav S., Wileman, Thomas and Green, Douglas R. (2020) Noncanonical function of an autophagy protein prevents spontaneous Alzheimer’s disease. Science Advances, 6 (33). eabb9036. ISSN 2375-2548

Durant, Lydia, Stentz, Régis, Noble, Alistair, Brooks, Johanne, Gicheva, Nadezhda, Reddi, Durga, O'Connor, Matthew J., Hoyles, Lesley, McCartney, Anne L., Man, Ripple, Pring, E. Tobias, Dilke, Stella, Hendy, Philip, Segal, Jonathan P., Lim, Dennis N.F., Misra, Ravi, Hart, Ailsa L., Arebi, Naila, Carding, Simon R. and Knight, Stella C. (2020) Bacteroides thetaiotaomicron-derived outer membrane vesicles promote regulatory dendritic cell responses in health but not in inflammatory bowel disease. Microbiome, 8 (1). ISSN 2049-2618

Noble, Alistair, Durant, Lydia, Hoyles, Lesley, McCartney, Anne L., Man, Ripple, Segal, Jonathan, Costello, Samuel P., Hendy, Philip, Reddi, Durga, Bouri, Sonia, Lim, Dennis N. F., Pring, Toby, O'Connor, Matthew J., Datt, Pooja, Wilson, Ana, Arebi, Naila, Akbar, Ayesha, Hart, Ailsa L., Carding, Simon R. and Knight, Stella C. (2020) Deficient resident memory T-cell and Cd8 T-cell response to commensals in inflammatory bowel disease. Journal of Crohn's & Colitis, 14 (4). 525–537. ISSN 1873-9946

Parker, Aimée, Fonseca, Sonia and Carding, Simon R. (2020) Gut microbes and metabolites as modulators of blood-brain barrier integrity and brain health. Gut Microbes, 11 (2). pp. 135-157. ISSN 1949-0976

Jones, Emily J., Booth, Catherine, Fonseca, Sonia, Parker, Aimee, Cross, Kathryn, Miquel-Clopés, Ariadna, Hautefort, Isabelle, Mayer, Ulrike ORCID: https://orcid.org/0000-0003-2328-0052, Wileman, Tom, Stentz, Régis and Carding, Simon R. (2020) The uptake, trafficking, and biodistribution of Bacteroides thetaiotaomicron generated outer membrane vesicles. Frontiers in Microbiology, 11. ISSN 1664-302X

Treveil, A, Sudhakar, P, Matthews, Z J, Wrzesiński, T, Jones, E J, Brooks, J, Ölbei, M, Hautefort, I, Hall, L J, Carding, S R, Mayer, U ORCID: https://orcid.org/0000-0003-2328-0052, Powell, P P ORCID: https://orcid.org/0000-0002-5347-0490, Wileman, T, Di Palma, F, Haerty, W and Korcsmáros, T (2020) Regulatory network analysis of Paneth cell and goblet cell enriched gut organoids using transcriptomics approaches. Molecular Omics, 16 (1). pp. 39-58. ISSN 2515-4184

Wang, Yingxue, Zhang, Weijiao, Jefferson, Matthew, Sharma, Parul, Bone, Benjamin, Kipar, Anja, Coombes, Janine L., Pearson, Tim, Man, Angela, Zhekova, Aleksandra, Bao, Yongping ORCID: https://orcid.org/0000-0002-6425-0370, Tripp, Ralph, Carding, Simon, Mayer, Ulrike ORCID: https://orcid.org/0000-0003-2328-0052, Powell, Penny ORCID: https://orcid.org/0000-0002-5347-0490, Stewart, James P. and Wileman, Tom (2020) The WD and linker domains of ATG16L1 required for non-canonical autophagy limit lethal influenza A virus infection at epithelial surfaces.

Carvalho, A L, Miquel-Clopés, A, Wegmann, U, Jones, E, Stentz, R, Telatin, A, Walker, N J, Butcher, W A, Brown, P J, Holmes, S, Dennis, M J, Williamson, E D, Funnell, S G P, Stock, M and Carding, S R (2019) Use of bioengineered human commensal gut bacteria-derived microvesicles for mucosal plague vaccine delivery and immunization. Clinical and Experimental Immunology, 196 (3). pp. 287-304. ISSN 0009-9104

Seton, Katharine and Carding, Simon (2019) The intestinal microbiota in health and disease. Microbiology Today. ISSN 1464-0570

Miquel-Clopés, A., Bentley, E. G., Stewart, J. P. and Carding, S. R. (2019) Mucosal vaccines and technology. Clinical and Experimental Immunology, 196 (2). pp. 205-214. ISSN 0009-9104

Sayers, Ellie, Dainty, Jack R. ORCID: https://orcid.org/0000-0002-0056-1233, Yates, Max ORCID: https://orcid.org/0000-0003-3977-8920, Verstappen, Suzanne M., Chipping, Jacqueline, Carding, Simon R., Luben, Robert N., Khaw, Kay-Tee, Wareham, Nick J. and Macgregor, Alexander J. ORCID: https://orcid.org/0000-0003-2163-2325 (2019) O14 Pro-inflammatory diets are associated with increased C-reactive protein and subsequent rheumatoid arthritis in the European Investigation of Cancer: Norfolk Arthritis Register cohort. Rheumatology, 58 (Supplement_3). ISSN 1462-0324

Rai, Shashank, Arasteh, Julia, Jefferson, Matthew, Pearson, Timothy, Wang, Yingxue, Zhang, Weijiao, Bicsak, Bertalan, Divekar, Devina, Powell, Penelope ORCID: https://orcid.org/0000-0002-5347-0490, Naumann, Ronald, Beraza, Naiara, Carding, Simon, Florey, Oliver, Mayer, Ulrike ORCID: https://orcid.org/0000-0003-2328-0052 and Wileman, Thomas (2019) The ATG5-binding and coiled coil domains of ATG16L1 maintain autophagy and tissue homeostasis in mice independently of the WD domain required for LC3 associated phagocytosis. Autophagy, 15 (4). pp. 599-612. ISSN 1554-8627

Jones, Emily J, Matthews, Zoe J, Gul, Lejla, Sudhakar, Padhmanand, Treveil, Agatha, Divekar, Devina, Buck, Jasmine, Wrzesinski, Tomasz, Jefferson, Matthew, Armstrong, Stuart D, Hall, Lindsay J ORCID: https://orcid.org/0000-0001-8938-5709, Watson, Alastair J M ORCID: https://orcid.org/0000-0003-3326-0426, Carding, Simon R, Haerty, Wilfried, Di Palma, Federica, Mayer, Ulrike ORCID: https://orcid.org/0000-0003-2328-0052, Powell, Penny P ORCID: https://orcid.org/0000-0002-5347-0490, Hautefort, Isabelle, Wileman, Tom and Korcsmaros, Tamas (2019) Integrative analysis of Paneth cell proteomic and transcriptomic data from intestinal organoids reveals functional processes dependent on autophagy. Disease Models & Mechanisms, 12 (3). ISSN 1754-8403

Carding, Simon (2019) Gut Health and Ageing. The Digest.

Carvalho, Ana L., Fonseca, Sonia, Miquel-Clopés, Ariadna, Cross, Kathryn, Kok, Khoon S., Wegmann, Udo, Gil-Cordoso, Katherine, Bentley, Eleanor G., Al Katy, Sanaria H.M., Coombes, Janine L., Kipar, Anja, Stentz, Regis, Stewart, James P. and Carding, Simon R. (2019) Bioengineering commensal bacteria-derived outer membrane vesicles for delivery of biologics to the gastrointestinal and respiratory tract. Journal of Extracellular Vesicles, 8 (1). ISSN 2001-3078

Mukhopadhya, Indrani, Segal, Jonathan P., Carding, Simon R., Hart, Ailsa L. and Hold, Georgina L. (2019) The gut virome:the ‘missing link’ between gut bacteria and host immunity? Therapeutic Advances in Gastroenterology, 12. ISSN 1756-283X

Sayers, Ellie, MacGregor, Alex ORCID: https://orcid.org/0000-0003-2163-2325 and R. Carding, Simon (2018) Drug-microbiota interactions and treatment response: Relevance to rheumatoid arthritis. AIMS Microbiology, 4 (4). pp. 642-654. ISSN 2471-1888

Stentz, Régis, Carvalho, Ana L., Jones, Emily J. and Carding, Simon R. (2018) Fantastic voyage: the journey of intestinal microbiota-derived microvesicles through the body. Biochemical Society Transactions, 46 (5). pp. 1021-1027. ISSN 0300-5127

Calder, P. C., Carding, S. R., Christopher, G., Kuh, D., Langley-Evans, S. C. and McNulty, H. (2018) A holistic approach to healthy ageing: how can people live longer, healthier lives? Journal of Human Nutrition and Dietetics, 31 (4). pp. 439-450. ISSN 0952-3871

Maijo, Monica, Ivory, Kamal, Clements, Sarah J, Dainty, Jack R ORCID: https://orcid.org/0000-0002-0056-1233, Jennings, Amy, Gillings, Rachel, Fairweather-Tait, Susan ORCID: https://orcid.org/0000-0002-1413-5569, Gulisano, Massimo, Santoro, Aurelia, Franceschi, Claudio, Carding, Simon R and Nicoletti, Claudio (2018) One-year consumption of a Mediterranean-like dietary pattern with vitamin D3 supplements induced small scale but extensive changes of immune cell phenotype, co-receptor expression and innate immune responses in healthy elderly subjects:Results from the United Kingdom arm of the NU-AGE trial. Frontiers in Physiology, 9. ISSN 1664-042X

Hoyles, Lesley, Snelling, Tom, Umlai, Umm-Kulthum, Nicholson, Jeremy K., Carding, Simon R., Glen, Robert C. and McArthur, Simon (2018) Microbiome–host systems interactions: protective effects of propionate upon the blood–brain barrier. Microbiome, 6. ISSN 2049-2618

Newberry, Fiona, Hsieh, Shen-Yuan, Wileman, Tom and Carding, Simon R. (2018) Does the microbiome and virome contribute to myalgic encephalomyelitis/chronic fatigue syndrome? Clinical Science, 132 (5). pp. 523-542. ISSN 0143-5221

Fletcher, Katherine, Ulferts, Rachel, Jacquin, Elise, Veith, Tabitha, Gammoh, Noor, Arasteh, Julia M, Mayer, Ulrike ORCID: https://orcid.org/0000-0003-2328-0052, Carding, Simon, Wileman, Thomas, Beale, Rupert and Florey, Oliver (2018) The WD40 domain of ATG16L1 is required for its non‐canonical role in lipidation of LC3 at single membranes. The EMBO Journal, 37 (4). ISSN 0261-4189

Clements, Sarah J. and R. Carding, Simon (2018) Diet, the intestinal microbiota, and immune health in aging. Critical Reviews in Food Science and Nutrition, 58 (4). pp. 651-661. ISSN 1040-8398

Clements, Sarah J., Maijo, Monica, Ivory, Kamal, Nicoletti, Claudio and Carding, Simon R. (2017) Age-associated decline in dendritic cell function and the impact of Mediterranean diet intervention in elderly subjects. Frontiers in Nutrition, 4. ISSN 2296-861X

Tomlinson, Matthew L., Butelli, Eugenio, Martin, Cathie and Carding, Simon R. (2017) Flavonoids from engineered tomatoes inhibit gut barrier pro-inflammatory cytokines and chemokines, via SAPK/JNK and p38 MAPK pathways. Frontiers in Nutrition, 4. ISSN 2296-861X

Bryant, William A., Stentz, Régis, Le Gall, Gwenaelle ORCID: https://orcid.org/0000-0002-1379-2196, Sternberg, Michael J. E., Carding, Simon R. and Wilhelm, Thomas (2017) In silico analysis of the small molecule content of outer membrane vesicles produced by Bacteroides thetaiotaomicron indicates an extensive metabolic link between microbe and host. Frontiers in Microbiology, 8. ISSN 1664-302X

Carding, S. R., Davis, N. and Hoyles, L. (2017) Review article: the human intestinal virome in health and disease. Alimentary Pharmacology and Therapeutics, 46 (9). 800–815. ISSN 0269-2813

Maclaren, Oliver J., Parker, Aimée, Pin, Carmen, Carding, Simon R., Watson, Alastair J. M. ORCID: https://orcid.org/0000-0003-3326-0426, Fletcher, Alexander G., Byrne, Helen M. and Maini, Phillip K. (2017) A hierarchical Bayesian model for understanding the spatiotemporal dynamics of the intestinal epithelium. PLoS Computational Biology, 13 (7). ISSN 1553-734X

Wegmann, Udo, Carvalho, Ana Lucia, Stocks, Martin and Carding, Simon R. (2017) Use of genetically modified bacteria for drug delivery in humans: Revisiting the safety aspect. Scientific Reports, 7. ISSN 2045-2322

Jones, Emily J., Korcsmaros, Tamas and Carding, Simon R. (2017) Mechanisms and pathways of Toxoplasma gondii transepithelial migration. Tissue Barriers, 5 (1). ISSN 2168-8370

Wegmann, Udo, Goesmann, Alexander and Carding, Simon R. (2016) Complete genome sequence of Bacteroides ovatus V975. Genome Announcements, 4 (6).

Horn, Nikki, Carvalho, Ana L., Overweg, Karin, Wegmann, Udo, Carding, Simon R. and Stentz, Régis (2016) A novel tightly regulated gene expression system for the human intestinal symbiont Bacteroides thetaiotaomicron. Frontiers in Microbiology, 7. ISSN 1664-302X

Navaneetharaja, Navena, Griffiths, Verity, Wileman, Tom and Carding, Simon (2016) A role for the intestinal microbiota and virome in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)? Journal of Clinical Medicine, 5 (6). ISSN 2077-0383

Clements, Sarah J. and Carding, Simon R. (2016) Can Nutritional Intervention Counteract Immunosenescence in the Elderly? In: Molecular Basis of Nutrition and Aging: A Volume in the Molecular Nutrition Series. Elsevier, pp. 375-391. ISBN 9780128018279

Huang, Yafei, Getahun, Andrew, Heiser, Ryan A., Detanico, Thiago O., Aviszus, Katja, Kirchenbaum, Greg A., Casper, Tamara L., Huang, Chunjian, Aydintug, M. Kemal, Carding, Simon R., Ikuta, Koichi, Huang, Hua, Wysocki, Lawrence J., Cambier, John C., O'Brien, Rebecca L. and Born, Willi K. (2016) γδ T cells shape preimmune peripheral B cell populations. Journal of Immunology, 196 (1). pp. 217-231. ISSN 0022-1767

Bernardo, David, Durant, Lydia, Mann, Elizabeth R., Bassity, Elizabeth, Montalvillo, Enrique, Man, Ripple, Vora, Rakesh, Reddi, Durga, Bayiroglu, Fahri, Fernández-Salazar, Luis, English, Nick. R., Peake, Simon T.C., Landy, Jon, Lee, Gui. H., Malietzis, George, Siaw, Yi Harn, Murugananthan, Aravinth U., Hendy, Phil, Sánchez-Recio, Eva, Phillips, Robin K.S., Garrote, Jose A., Scott, Paul, Parkhill, Julian, Paulsen, Malte, Hart, Ailsa L., Al-Hassi, Hafid O., Arranz, Eduardo, Walker, Alan W., Carding, Simon R. and Knight, Stella C. (2016) Chemokine (C-C Motif) Receptor 2 mediates dendritic cell recruitment to the human colon but is not responsible for differences observed in dendritic cell subsets, phenotype, and function between the proximal and distal colon. Cellular and Molecular Gastroenterology and Hepatology, 2 (1). 22-39.e5. ISSN 2352-345X

Weight, Caroline, Jones, Emily, Horn, Nikki, Wellner, Nikolaus and Carding, Simon (2015) Elucidating pathways of Toxoplasma gondii invasion in the gastrointestinal tract: involvement of the tight junction protein occludin. Microbes and Infection, 17 (10). pp. 698-709. ISSN 1286-4579

Stentz, Régis, Horn, Nikki, Cross, Kathryn, Salt, Louise, Brearley, Charles ORCID: https://orcid.org/0000-0001-6179-9109, Livermore, David M. ORCID: https://orcid.org/0000-0002-9856-3703 and Carding, Simon R. (2015) Cephalosporinases associated with outer membrane vesicles released by Bacteroides spp. protect gut pathogens and commensals against beta-lactam antibiotics. Journal of Antimicrobial Chemotherapy, 70 (3). pp. 701-709. ISSN 0305-7453

Carding, Simon, Verbeke, Kristin, Vipond, Daniel T., Corfe, Bernard M. and Owen, Lauren J. (2015) Dysbiosis of the gut microbiota in disease. Microbial Ecology, 26 (1). pp. 26191-26200. ISSN 0095-3628

Pin, Carmen, Parker, Aimee, Gunning, A. Patrick, Ohta, Yuki, Johnson, Ian T., Carding, Simon R. and Sato, Toshiro (2015) An individual based computational model of intestinal crypt fission and its application to predicting unrestrictive growth of the intestinal epithelium. Integrative Biology, 7. pp. 213-228. ISSN 1757-9694

Huang, Yafei, Heiser, Ryan A., Detanico, Thiago O., Getahun, Andrew, Kirchenbaum, Greg A., Casper, Tamara L., Aydintug, M. Kemal, Carding, Simon R., Ikuta, Koichi, Huang, Hua, Cambier, John C., Wysock, Lawrence J., O’Brien, Rebecca L. and Born, Willi K. (2015) γδ T cells affect IL-4 production and B-cell tolerance. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 112 (1). E39-E48. ISSN 1091-6490

Bowcutt, Rowann, Forman, Ruth, Glymenaki, Maria, Else, Kathryn Jane, Carding, Simon Richard and Cruickshank, Sheena Margaret (2014) Heterogeneity across the murine small and large intestine. World Journal of Gastroenterology, 20 (41). pp. 15216-15323. ISSN 1007-9327

Bowcutt, L., Bramhall, L., Longunova, L., Booth, C., Carding, S. R., Grencis, R. and Cruickshank, S. (2014) A role for the pattern recognition receptor Nod2 in promoting recruitment of CD103+ dendritic cells in the colon in response to Trichuis muris infection. Mucosal Immunology, 7 (5). pp. 1094-1105. ISSN 1933-0219

Kober, Olivia, Pin, Carmen, Holm, Lena, Carding, Simon and Juge, Nathalie (2014) γδ T-cell-deficient mice show alterations in mucin expression, glycosylation and goblet cells but maintain an intact mucus layer. American Journal of Physiology, 306. pp. 582-589. ISSN 0002-9513

Maijó, Mònica, Clements, Sarah J., Ivory, Kamal, Nicoletti, Claudio and Carding, Simon (2014) Nutrition, diet and immunosenescence. Mechanisms of Ageing and Development, 136-137. pp. 116-128. ISSN 0047-6374

Stentz, Régis, Osborne, Samantha, Horn, Nikki, Li, Arthur, Hautefort, Isabelle, Bongaerts, Roy, Rouyer, Marine, Bailey, Paul, Shears, Stephen B., Hemmings, Andrew ORCID: https://orcid.org/0000-0003-3053-3134, Brearley, Charles A. ORCID: https://orcid.org/0000-0001-6179-9109 and Carding, Simon (2014) A bacterial homolog of a eukaryotic inositol phosphate signaling enzyme mediates cross-kingdom dialog in the mammalian gut. Cell Reports, 6 (4). pp. 646-656. ISSN 2211-1247

Walker, Catherine R., Hautefort, Isabelle, Dalton, Jane E., Overweg, Karin, Egan, Charlotte E., Bongaerts, Roy J., Newton, Darren J., Cruickshank, Sheena M., Andrew, Elizabeth M. and Carding, Simon R. (2013) Intestinal intraepithelial lymphocyte-enterocyte crosstalk regulates production of bactericidal angiogenin 4 by Paneth cells upon microbial challenge. PLoS One, 8 (12). ISSN 1932-6203

Wegmann, Udo, Horn, Nikki and Carding, Simon R (2013) Defining the bacteroides ribosomal binding site. Applied and Environmental Microbiology, 79 (6). pp. 1980-9. ISSN 0099-2240

Meader, Emma, Mayer, Melinda J, Steverding, Dietmar, Carding, Simon R and Narbad, Arjan (2013) Evaluation of bacteriophage therapy to control Clostridium difficile and toxin production in an in vitro human colon model system. Anaerobe, 22. pp. 25-30. ISSN 1095-8274

Weight, Caroline M and Carding, Simon R (2012) The protozoan pathogen Toxoplasma gondii targets the paracellular pathway to invade the intestinal epithelium. Annals of the New York Academy of Sciences, 1258. pp. 135-42. ISSN 0077-8923

Pin, Carmen, Watson, Alastair J. M. ORCID: https://orcid.org/0000-0003-3326-0426 and Carding, Simon R. (2012) Modelling the spatio-temporal cell dynamics reveals novel insights on cell differentiation and proliferation in the small intestinal crypt. PLoS One, 7 (5). ISSN 1932-6203

Marsh, Lorraine, Coletta, P Louise, Hull, Mark A, Selby, Peter J and Carding, Simon R (2012) Altered intestinal epithelium-associated lymphocyte repertoires and function in ApcMin/+ mice. International Journal of Oncology, 40 (1). pp. 243-50. ISSN 1019-6439

Hamady, Zaed Z. R., Scott, Nigel, Farrar, Mark D., Wadhwa, Meenu, Dilger, Paula, Whitehead, Terence R., Thorpe, Robin, Holland, Keith T., Lodge, Peter J. A. and Carding, Simon R. (2011) Treatment of colitis with a commensal gut bacterium engineered to secrete human tgf-β1 under the control of dietary xylan 1. Inflammatory Bowel Diseases, 17 (9). pp. 1925-1935.

Stappenbeck, Thaddeus S., Rioux, John D., Mizoguchi, Atsushi, Saitoh, Tatsuya, Huett, Alan, Darfeuille-Michaud, Arlette, Wileman, Tom, Mizushima, Noboru, Carding, Simon, Akira, Shizuo, Parkes, Miles and Xavier, Ramnik J. (2011) Crohn disease: A current perspective on genetics, autophagy and immunity. Autophagy, 7 (4). pp. 355-374. ISSN 1554-8627

Meader, Emma, Mayer, Melinda J., Gasson, Michael J., Steverding, Dietmar, Carding, Simon R. and Narbad, Arjan (2010) Bacteriophage treatment significantly reduces viable Clostridium difficile and prevents toxin production in an in vitro model system. Anaerobe, 16 (6). pp. 549-554. ISSN 1095-8274

Hamady, Zaed Z. R., Scott, Nigel, Farrar, Mark D., Lodge, J. Peter A., Holland, Keith T., Whitehead, Terence R. and Carding, Simon R. (2010) Xylan-regulated delivery of human keratinocyte growth factor-2 to the inflamed colon by the anaerobic bacterium Bacteroides ovatus. Gut, 59 (4). pp. 461-469. ISSN 1468-3288

Cruickshank, Sheena M., Deschoolmeester, Matthew L., Svensson, Marcus, Howell, Gareth, Bazakou, Aikaterini, Logunova, Larisa, Little, Matthew C., English, Nicholas, Mack, Matthias, Grencis, Richard K., Else, Kathryn J. and Carding, Simon R. (2009) Rapid dendritic cell mobilization to the large intestinal epithelium is associated with resistance to Trichuris muris infection. Journal of Immunology, 182 (5). pp. 3055-3062. ISSN 1550-6606

Tramonti, D., Rhodes, K. A., Martin, N. G., Dalton, J. E., Andrew, E. and Carding, S. R. (2008) Gamma-delta T cell-mediated regulation of chemokine producing macrophages during Listeria monocytogenes infection-induced inflammation. The Journal of Pathology, 216 (2). pp. 262-270. ISSN 1096-9896

Rhodes, Katherine A, Andrew, Elizabeth M, Newton, Darren J, Tramonti, Daniela and Carding, Simon R (2008) A subset of IL-10-producing gammadelta T cells protect the liver from Listeria-elicited, CD8(+) T cell-mediated injury. European Journal of Immunology, 38 (8). pp. 2274-2283. ISSN 0014-2980

Patel, A., Jagadesham, V., Porter, K. E., Scott, D. and Carding, S. (2008) Characterisation of fractalkine/CX3CL1 and fractalkine receptor (CX3CR1) expression in abdominal aortic aneurysm disease. European Journal of Vascular and Endovascular Surgery, 36 (1). pp. 20-27. ISSN 1532-2165

Cruickshank, Sheena M., Wakenshaw, Louise, Cardone, John, Howdle, Peter D., Murray, Peter J. and Carding, Simon R. (2008) Evidence for the involvement of NOD2 in regulating colonic epithelial cell growth and survival. World Journal of Gastroenterology, 14 (38). pp. 5834-5841. ISSN 2219-2840

Hamady, Zaed Z. R., Farrar, Mark D., Whitehead, Terence R., Holland, Keith T., Lodge, J. Peter A. and Carding, Simon (2008) Identification and use of the putative Bacteroides ovatus xylanase promoter for the inducible production of recombinant human proteins. Microbiology, 154 (10). pp. 3165-3174. ISSN 1465-2080

Jagadesham, Vamshi P., Scott, D. Juilan A. and Carding, Simon R. (2008) Abdominal aortic aneurysms: An autoimmune disease? Trends in Molecular Medicine, 14 (12). pp. 522-529. ISSN 1471-499X

Kirby, Alun C., Newton, Darren J., Carding, Simon R. and Kaye, Paul M. (2007) Evidence for the involvement of lung-specific gamma delta T cell subsets in local responses to Streptococcus pneumoniae infection. European Journal of Immunology, 37 (12). pp. 3404-3413.

Baumgart, Daniel C and Carding, Simon R (2007) Inflammatory bowel disease: cause and immunobiology. The Lancet, 369 (9573). pp. 1627-1640. ISSN 1474-547X

Kirby, A. C., Newton, D. J., Carding, S. R. and Kaye, P. M. (2007) Pulmonary dendritic cells and alveolar macrophages are regulated by gamma delta T cells during the resolution of S. pneumoniae-induced inflammation. The Journal of Pathology, 212 (1). pp. 29-37. ISSN 1096-9896

Swerdlow, Mathew P., Kennedy, Douglas R., Kennedy, Jeffrey S., Washabau, Robert J., Henthorn, Paula S., Moore, Peter F., Carding, Simon R. and Felsburg, Peter J. (2006) Expression and function of TLR2, TLR4, and Nod2 in primary canine colonic epithelial cells. Veterinary Immunology and Immunopathology, 114 (3-4). pp. 313-319. ISSN 1873-2534

Dalton, Jane E, Cruickshank, Sheena M, Egan, Charlotte E, Mears, Rainy, Newton, Darren J, Andrew, Elizabeth M, Lawrence, Beth, Howell, Gareth, Else, Kathryn J, Gubbels, Marc-Jan, Striepen, Boris, Smith, Judith E, White, Stanley J and Carding, Simon R (2006) Intraepithelial γδ+ lymphocytes maintain the integrity of intestinal epithelial tight junctions in response to infection. Gastroenterology, 131 (3). pp. 818-829. ISSN 1528-0012

Tramonti, Daniela, Andrew, Elizabeth M, Rhodes, Kate, Newton, Darren J and Carding, Simon R (2006) Evidence for the opposing roles of different γδ T cell subsets in macrophage homeostasis. European Journal of Immunology, 36 (7). pp. 1729-1738. ISSN 0014-2980

Newton, Darren J, Andrew, Elizabeth M, Dalton, Jane E, Mears, Rainy and Carding, Simon R (2006) Identification of novel gammadelta T-cell subsets following bacterial infection in the absence of Vgamma1+ T cells:homeostatic control of gammadelta T-cell responses to pathogen infection by Vgamma1+ T cells. Infection and Immunity, 74 (2). pp. 1097-1105. ISSN 0019-9567

Forester, N. D., Cruickshank, S. M., Scott, D. J. A. and Carding, S. R. (2006) Increased natural killer cell activity in patients with an abdominal aortic aneurysm. British Journal of Surgery, 93 (1). pp. 46-54. ISSN 0007-1323

Egan, Charlotte E., Dalton, Jane E., Andrew, Elizabeth M., Smith, Judith E., Gubbels, Marc-Jan, Striepen, Boris and Carding, Simon R. (2005) A requirement for the Vgamma1+ subset of peripheral gammadelta T cells in the control of the systemic growth of Toxoplasma gondii and infection-induced pathology. Journal of Immunology, 175 (12). pp. 8191-8199. ISSN 0022-1767

Cruickshank, Sheena M., English, Nicholas R., Felsburg, Peter J. and Carding, Simon R. (2005) Characterization of colonic dendritic cells in normal and colitic mice. World Journal of Gastroenterology, 11 (40). pp. 6338-6347. ISSN 1007-9327

Andrew, Elizabeth M., Newton, Darren J., Dalton, Jane E., Egan, Charlotte E., Goodwin, Stewart J., Tramonti, Daniela, Scott, Philip and Carding, Simon R. (2005) Delineation of the function of a major gamma delta T cell subset during infection. Journal of Immunology, 175 (3). pp. 1741-1750. ISSN 0022-1767

Forester, Nerys D., Cruickshank, Sheena M., Scott, D. Julian A. and Carding, Simon R (2005) Functional characterization of T cells in abdominal aortic aneurysms. Immunology, 115 (2). pp. 262-270. ISSN 0019-2805

Andrew, Elizabeth M and Carding, Simon R (2005) Murine gammadelta T cells in infections: beneficial or deleterious? Microbes and Infection, 7 (3). pp. 529-536. ISSN 1286-4579

Farrar, M.D., Whitehead, T.R., Lan, J., Dilger, P., Thorpe, R., Holland, K.T. and Carding, S.R. (2005) Engineering of the gut commensal bacterium Bacteroides ovatus to produce and secrete biologically active murine interleukin-2 in response to xylan. Journal of Applied Microbiology, 98 (5). pp. 1191-1197. ISSN 1364-5072

Dalton, Jane E., Howell, Gareth, Pearson, Jayne, Scott, Phillip and Carding, Simon R. (2004) Fas-Fas ligand interactions are essential for the binding to and killing of activated macrophages by gamma delta T cells. Journal of Immunology, 173 (6). pp. 3660-3667. ISSN 0022-1767

Cruickshank, S M, McVay, LD, Baumgart, DC, Felsburg, PJ and Carding, SR (2004) Colonic epithelial cell mediated suppression of CD4 T cell activation. Gut, 53 (5). pp. 678-684. ISSN 0017-5749

Singh, Joy Carmelina Indira, Cruickshank, Sheena Margaret, Newton, Darren James, Wakenshaw, Louise, Graham, Anne, Lan, Jinggang, Lodge, Jeremy Peter Alan, Felsburg, Peter John and Carding, Simon Richard (2004) Toll-like receptor-mediated responses of primary intestinal epithelial cells during the development of colitis. AJP: Gastrointestinal and Liver Physiology, 288 (3). G514-G524. ISSN 0193-1857

Dalton, Jane E., Pearson, Jayne, Scott, Phillip and Carding, Simon R. (2003) The interaction of gamma delta T cells with activated macrophages is a property of the V gamma 1 subset. Journal of Immunology, 171 (12). pp. 6488-6494. ISSN 0022-1767

Ashcroft, A. J., Cruickshank, S. M., Croucher, P. I., Perry, M. J., Rollinson, S., Lippitt, J. M., Child, J. A., Dunstan, C., Felsburg, P. J., Morgan, G. J. and Carding, S. R. (2003) Colonic dendritic cells, intestinal inflammation, and T cell-mediated bone destruction are modulated by recombinant osteoprotegerin. Immunity, 19 (6). pp. 849-861. ISSN 1097-4180

Villegas, Eric N., Lieberman, Linda A., Carding, Simon R. and Hunter, Christopher A. (2002) Susceptibility of interleukin-2-deficient mice to Toxoplasma gondii is associated with a defect in the production of gamma interferon. Infection and Immunity, 70 (9). pp. 4757-4761. ISSN 0019-9567

Carding, Simon R and Egan, Paul J (2002) Gammadelta T cells: Functional plasticity and heterogeneity. Nature Reviews Immunology, 2 (5). pp. 336-345. ISSN 1474-1733