Nutrition, diet and immunosenescence

Maijó, Mònica, Clements, Sarah J., Ivory, Kamal, Nicoletti, Claudio and Carding, Simon (2014) Nutrition, diet and immunosenescence. Mechanisms of Ageing and Development, 136-137. pp. 116-128. ISSN 0047-6374

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Ageing is characterized by immunosenescence and the progressive decline in immunity in association with an increased frequency of infections and chronic disease. This complex process affects both the innate and adaptive immune systems with a progressive decline in most immune cell populations and defects in activation resulting in loss of function. Although host genetics and environmental factors, such as stress, exercise and diet can impact on the onset or course of immunosenescence, the mechanisms involved are largely unknown. This review focusses on identifying the most significant aspects of immunosenescence and on the evidence that nutritional intervention might delay this process, and consequently improve the quality of life of the elderly.

Item Type: Article
Uncontrolled Keywords: immunosenescence,ageing,nutrition
Faculty \ School: Faculty of Science > School of Biological Sciences
Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Pure Connector
Date Deposited: 01 Apr 2016 14:00
Last Modified: 22 Jul 2020 00:46
DOI: 10.1016/j.mad.2013.12.003

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