Items where Author is "Wheeler, Grant"

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Alrefaei, Abdulmajeed Fahad, Münsterberg, Andrea E. and Wheeler, Grant N. (2021) Expression analysis of chick Frizzled receptors during spinal cord development. Gene Expression Patterns, 39. ISSN 1567-133X

Mok, Gi Fay, Folkes, Leighton, Weldon, Shannon A., Maniou, Eirini, Martinez-Heredia, Victor, Godden, Alice M., Williams, Ruth M., Sauka-Spengler, Tatjana, Wheeler, Grant N., Moxon, Simon and Münsterberg, Andrea E. (2021) Characterising open chromatin in chick embryos identifies cis-regulatory elements important for paraxial mesoderm formation and axis extension. Nature Communications, 12 (1). ISSN 2041-1723

Saide, Katy and Wheeler, Grant N (2020) In Vivo Assessment of Drug-Induced Hepatotoxicity Using Xenopus Embryos. Cold Spring Harbor Protocols. pp. 470-477. ISSN 1559-6095

Alrefaei, Abdulmajeed, Munsterberg, Andrea and Wheeler, Grant (2020) FZD10 regulates cell proliferation and mediates Wnt1 induced neurogenesis in the developing spinal cord. PLoS One, 15 (6). ISSN 1932-6203

Herrera-Úbeda, Carlos, Marín-Barba, Marta, Navas-Pérez, Enrique, Gravemeyer, Jan, Albuixech-Crespo, Beatriz, Wheeler, Grant N. and Garcia-Fernàndez, Jordi (2019) Microsyntenic Clusters Reveal Conservation of lncRNAs in Chordates Despite Absence of Sequence Conservation. Biology, 8. ISSN 2079-7737

Rivero, M., Marín-Barba, M., Gutierrez, L., Lozano Velasco, E., Wheeler, G. N., Sánchez-Marcos, J., Muñoz-Bonilla, A., Morris, Christopher and Ruiz, A. (2019) Toxicity and biodegradation of zinc ferrite nanoparticles in Xenopus laevis. Journal of Nanoparticle Research, 21. ISSN 1388-0764

Saide, Katy, Sherwood, Victoria and Wheeler, Grant N. (2019) Paracetamol-induced liver injury modelled in Xenopus laevis embryos. Toxicology Letters, 302. pp. 83-91. ISSN 0378-4274

Gonzalez-Paredes, Ana, Sitia, Leopoldo, Ruyra, Angels, Morris, Christopher, Wheeler, Grant N., McArthur, Michael and Gasco, Paolo (2019) Solid lipid nanoparticles for the delivery of anti-microbial oligonucleotides. European Journal of Pharmaceutics and Biopharmaceutics, 134. pp. 166-177. ISSN 0939-6411

Desanlis, Ines, Felstead, Hannah L., Edwards, Dylan R. and Wheeler, Grant N. (2018) ADAMTS9, a member of the ADAMTS family, in Xenopus development. Gene Expression Patterns, 29. pp. 72-81. ISSN 1567-133X

Mok, Gi Fay, Lozano-Velasco, Estefania, Maniou, Eirini, Viaut, Camille, Moxon, Simon, Wheeler, Grant and Münsterberg, Andrea (2018) miR-133-mediated regulation of the Hedgehog pathway orchestrates embryo myogenesis. Development, 145 (12). ISSN 0950-1991

Ward, Nicole, Green, Darrell, Higgins, Janet, Dalmay, Tamas, Munsterberg, Andrea, Moxon, Simon and Wheeler, Grant (2018) microRNAs associated with early neural crest development in Xenopus laevis. BMC Genomics, 19. ISSN 1471-2164

Marin-Barba, Marta, Gavilán, Helena, Gutierrez, Lucia, Lozano Velasco, Estefania, Rodriguez Ramiro, Ildefonso, Wheeler, Grant, Morris, Christopher J., Morales, M. Puerto and Ruiz, Amalia (2018) Unravelling the mechanisms that determine the uptake and metabolism of magnetic single and multicore nanoparticles in a Xenopus laevis model. Nanoscale, 10 (2). pp. 690-704. ISSN 2040-3364

Hanson, Kimberley, Robinson, Stephen, Al-Yousuf, Karamallah, Hendry, Adam, Sexton, Darren, Sherwood, Victoria and Wheeler, Grant (2018) The anti-rheumatic drug, leflunomide, synergizes with MEK inhibition to suppress melanoma growth. Oncotarget, 9. pp. 3815-3829. ISSN 1949-2553

Abu-Elmagd, Muhammad, Mulvaney, Joanna and Wheeler, Grant N. (2017) Frizzled-7 is required for Xenopus heart development. Biology Open, 6 (12). pp. 1861-1868. ISSN 2046-6390

Mamusa, Marianna, Sitia, Leopoldo, Barbero, Francesco, Ruyra, Angels, Díaz Calvo, Teresa, Montis, Costanza, Gonzalez-Paredes, Ana, Wheeler, Grant N., Morris, Christopher J., McArthur, Michael and Berti, Debora (2017) Cationic liposomal vectors incorporating a bolaamphiphile for oligonucleotide antimicrobials. Biochimica et Biophysica Acta (BBA) - Biomembranes, 1859 (10). 1767–1777. ISSN 0005-2736

Al-Yousuf, Karamallah, Webster, Carl A., Wheeler, Grant N., Baldelli Bombelli, Francesca and Sherwood, Victoria (2017) Combining cytotoxicity assessment and Xenopus laevis phenotypic abnormality assay as a predictor of nanomaterial safety. Current Protocols in Toxicology, 73 (1). 20.13.1–20.13.33.

Williams, Ruth, Winkfein, Robert, Ginger, Rebecca, Green, Martin, Schnetkamp, Paul and Wheeler, Grant (2017) A functional approach to understanding the role of NCKX5 in Xenopus pigmentation. PLoS One, 12 (7). ISSN 1932-6203

Hatch, Victoria, Marin Barba, Marta, Moxon, Simon, Ford, Christopher, Ward, Nicole, Tomlinson, Matthew, Desanlis, Ines, Hendry, Adam, Hontelez, Saartje, van Krujsbergen, Ila, Veenstra, Gert Jan, Munsterberg, Andrea and Wheeler, Grant (2016) The positive transcriptional elongation factor (P-TEFb) is required for neural crest specification. Developmental Biology, 416 (2). 361–372. ISSN 0012-1606

Webster, Carl, Di Silvio, Desire, Devarajan, Aarthi, Bigini, Paolo, Micotti, Eduardo, Giudice, Chiari, Salmona, Mario, Wheeler, Grant, Sherwood, Victoria and Baldelli Bombelli, Francesca (2016) An early developmental vertebrate model for nanomaterial safety:bridging cell-based and mammalian toxicity assessment. Nanomedicine, 11 (6). pp. 643-656. ISSN 1743-5889

Ahmed, Ayisha, Ward, Nicole J., Moxon, Simon, Lopez-Gomollon, Sara, Viaut, Camille, Tomlinson, Matthew L., Patrushev, Ilya, Gilchrist, Michael J., Dalmay, Tamas, Dotlic, Dario, Munsterberg, Andrea E. and Wheeler, Grant N. (2015) A database of microRNA expression patterns in Xenopus laevis. PLoS One, 10 (10). ISSN 1932-6203

Abou-Elhamd, Alaa, Alrefaei, Abdulmajeed, Mok, Gi Fay (Geoffrey), Garcia-Morales, Carla, Abu-Elmagd, Muhammad, Wheeler, Grant and Munsterberg, Andrea (2015) Klhl31 attenuates β-catenin dependent Wnt signaling and regulates embryo myogenesis. Developmental Biology, 402 (1). pp. 61-71. ISSN 0012-1606

Kelwick, Richard, Desanlis, Ines, Wheeler, Grant N and Edwards, Dylan R (2015) The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) family. Genome Biology, 16. ISSN 1465-6906

Abu-Elmagd, Muhammad, Goljanek-Whysall, Katarzyna, Wheeler, Grant and Munsterberg, Andrea (2015) Sprouty2 mediated tuning of signalling is essential for somite myogenesis. BMC Medical Genomics, 8 (Suppl 1). ISSN 1755-8794

Hoppler, S. and Wheeler, Grant (2015) It's about time for neural crest. Science, 348 (6241). pp. 1316-1317. ISSN 0036-8075

Goljanek-Whysall, Katarzyna, Mok, Gi Fay (Geoffrey), Alrefaei, Abdulmajeed, Kennerley, Niki, Wheeler, Grant and Munsterberg, Andrea (2014) myomiR-dependent switching of BAF60 variant incorporation into Brg1 chromatin remodeling complexes during embryo myogenesis. Development, 141. pp. 3378-3387. ISSN 0950-1991

Song, Junfang, Mccoll, James, Camp Navarro, Ester, Kennerley, Nicola, Mok, Geoffrey, Mccormick, Dominique, Grocott, Timothy, Wheeler, Grant and Munsterberg, Andrea (2014) Smad1 transcription factor integrates BMP2 and Wnt3a signals in migrating cardiac progenitor cells. Proceedings of the National Academy of Sciences, 111 (20). pp. 7337-7342. ISSN 0027-8424

Drakakis, Georgios, Hendry, Adam, Hanson, Kimberley, Brewerton, Suzanne, Bodkin, Michael, Evans, David, Wheeler, Grant and Bender, Andreas (2014) Bioactivity Profile Analysis from Automated Phenotype Detection in Xenopus laevis Using Image Processing. MedChemComm, 5 (3). pp. 386-396. ISSN 2040-2511

Liggi, Sonia, Drakakis, Georgios, Hendry, Adam, Hanson, Kimberley, Brewerton, Suzanne, Wheeler, Grant, Bodkin, Michael, Evans, David and Bender, Andreas (2013) Extensions to In Silico Bioactivity Predictions Using Pathway Annotations and Differential Pharmacology Analysis: Application to Xenopus laevis Phenotypic Readouts. Molecular Informatics, 32. pp. 1009-1024. ISSN 1868-1751

Wheeler, Grant N. and Liu, Karen J. (2012) Xenopus: An ideal system for chemical genetics. genesis, 50 (3). pp. 207-218.

Tomlinson, Matthew, Henry, Adam and Wheeler, Grant (2012) Chemical genetics and drug discovery in Xenopus. Methods in Molecular Biology, 917. pp. 155-166. ISSN 1940-6029

White, Richard Mark, Cech, Jennifer, Ratanasirintrawoot, Sutheera, Lin, Charles Y., Rahl, Peter B., Burke, Christopher J., Langdon, Erin, Tomlinson, Matthew L., Mosher, Jack, Kaufman, Charles, Chen, Frank, Long, Hannah K., Kramer, Martin, Datta, Sumon, Neuberg, Donna, Granter, Scott, Young, Richard A., Morrison, Sean, Wheeler, Grant N. and Zon, Leonard I. (2011) DHODH modulates transcriptional elongation in the neural crest and melanoma. Nature, 471 (7339). pp. 518-522. ISSN 0028-0836

Tomlinson, Mark L., Guan, Pingping, Morris, Richard J., Fidock, Mark D., Rejzek, Martin, Garcia Morales, Carla, Field, Robert A. and Wheeler, Grant N. (2009) A chemical genomic approach identifies matrix metalloptroteinases as playing an essential and specific role in Xenopus melanophore migration. Chemistry and Biology, 16 (1). pp. 93-104. ISSN 1879-1301

Garcia-Morales, Carla, Liu, Chiung-Hui, Abu-Elmagd, Muhammad, Hajihosseini, Mohammad K. and Wheeler, Grant N. (2009) Frizzled-10 promotes sensory neuron development in Xenopus embryos. Developmental Biology, 335 (1). pp. 143-155. ISSN 1095-564X

Tomlinson, Matthew L., Rejzek, Martin, Fidock, Mark, Field, Robert A. and Wheeler, Grant N. (2009) Chemical genomics identifies compounds affecting Xenopus laevis pigment cell development. Molecular BioSystems, 5 (4). pp. 376-384.

Wheeler, Grant N. and Brändli, André W. (2009) Simple vertebrate models for chemical genetics and drug discovery screens: Lessons from zebrafish and Xenopus. Developmental Dynamics, 238 (6). pp. 1287-1308. ISSN 1097-0177

Lavery, Danielle L., Davenport, Ian R., Turnbull, Yvonne D., Wheeler, Grant N. and Hoppler, Stefan (2008) Wnt6 expression in epidermis and epithelial tissues during Xenopus organogenesis. Developmental Dynamics, 237 (3). pp. 768-779. ISSN 1097-0177

Tomlinson, M, Abu-Elmagd, M, Garcia-Morales, C and Wheeler, GN (2008) Three matrix metalloproteinases are required in vivo for macrophage migration during embryonic development. Mechanisms of Development, 125. pp. 1059-1070. ISSN 1872-6356

Wheeler, G.N., Lavery, D. and Hoppler, S. (2008) Inducible gene expression in transient transgenic Xenopus embryos. Methods in Molecular Biology, 469. pp. 431-449. ISSN 1940-6029

Grocott, Timothy, Frost, Victoria, Maillard, Marjorie, Johansen, Terje, Wheeler, Grant N., Dawes, Lucy J., Wormstone, I. Michael and Chantry, Andrew (2007) The MH1 domain of Smad3 interacts with Pax6 and represses autoregulation of the Pax6 P1 promoter. Nucleic Acids Research, 35 (3). pp. 890-901. ISSN 0305-1048

Sweetman, Dylan, Rathjen, Tina, Jefferson, Matthew, Wheeler, Guy, Smith, Terence G, Wheeler, Grant N, Münsterberg, Andrea and Dalmay, Tamas (2006) FGF-4 signaling is involved in mir-206 expression in developing somites of chicken embryos. Developmental Dynamics, 235 (8). pp. 2185-2191. ISSN 1097-0177

Abu-Elmagd, Muhammad, Garcia-Morales, Carla and Wheeler, Grant N. (2006) Frizzled7 mediates canonical Wnt signaling in neural crest induction. Developmental Biology, 298 (1). pp. 285-298. ISSN 0012-1606

Tomlinson, Matthew L., Field, Robert A. and Wheeler, Grant N. (2005) Xenopus as a model organism in Developmental chemical genetic screens. Molecular BioSystems, 1 (3). pp. 223-228. ISSN 1742-206X

Harrison, Michael, Abu-elmagd, Muhammad, Grocott, Timothy, Yates, Clara, Gavrilovic, Jelena and Wheeler, Grant N. (2004) Matrix metalloproteinase genes inXenopus development. Developmental Dynamics, 231 (1). pp. 214-220. ISSN 1058-8388

Munsterburg, A., Yue, Q., Abu-Elmagd, M., Wagstaff, L. and Wheeler, G.N (2004) The molecular mechanisms controlling cardiac precursor cell specification and movements. The BSCR Bulletin, 17. pp. 5-10.

Hamilton, F.S., Wheeler, G.N. and Hoppler, S. (2001) Difference in XTcf-3 dependency accounts for change in response to b-catenin-mediated Wnt signalling in Xenopus blastula. Development, 128. pp. 2063-2073. ISSN 1477-9129

Wheeler, Grant N. and Hynes, Richard O. (2001) The cloning, genomic organization and expression of the focal contact protein paxillin in Drosophila. Gene, 262 (1-2). pp. 291-299. ISSN 0378-1119

Wheeler, Grant N., Hamilton, Fiona S and Hoppler, Stefan (2000) Inducible gene expression in transgenic Xenopus embryos. Current Biology, 10 (14). pp. 849-852. ISSN 0960-9822

Geerts, Dirk, Fontao, Lionel, Nievers, Mirjam G., Schaapveld, Roel Q., Purkis, Patricia E., Wheeler, Grant N, Lane, E. Birgitte, Leigh, Irene M. and Sonnenberg, Arnoud (1999) Binding of integrin alpha6beta4 to plectin prevents plectin association with F-actin but does not interfere with intermediate filament binding. Journal of Cell Biology, 147 (2). pp. 417-434. ISSN 0021-9525

Wheeler, G N and Hoppler, S (1999) Two novel Xenopus frizzled genes expressed in developing heart and brain. Mechanisms of Development, 86 (1-2). pp. 203-207. ISSN 0925-4773

Buxton, Roger S., Wheeler, Grant N., Pidsley, Sara C., Marsden, Mark D., Adams, Michael J., Jenkins, Nancy A., Gilbert, Debra J. and Copeland, Neal G. (1994) Mouse desmocollin (Dsc3) and desmoglein (Dsg1) genes are closely linked in the proximal region of chromosome 18. Genomics, 21 (3). pp. 510-6. ISSN 0888-7543

Wheeler, Grant N., Buxton, Roger S., Parker, Andrew E., Arnemann, Joachim, Rees, David A., King, Ian A. and Magee, Anthony I. (1991) Desmosomal glycoproteins I, II and III:novel members of the cadherin superfamily. Biochemical Society Transactions, 19 (4). pp. 1060-1064. ISSN 0300-5127

Arnemann, Joachim, Spurr, Nigel K, Wheeler, Grant N., Parker, Andrew E. and Buxton, Roger S. (1991) Chromosomal assignment of the human genes coding for the major proteins of the desmosome junction, desmoglein DGI (DSG), desmocollins DGII/III (DSC), desmoplakins DPI/II (DSP), and plakoglobin DPIII (JUP). Genomics, 10 (3). pp. 640-645. ISSN 1089-8646

Parker, A E, Wheeler, G N, Arnemann, J, Pidsley, S C, Ataliotis, P, Thomas, C L, Rees, D A, Magee, A I and Buxton, R S (1991) Desmosomal glycoproteins II and III. Cadherin-like junctional molecules generated by alternative splicing. Journal of Biological Chemistry, 266 (16). pp. 10438-10445. ISSN 0021-9258

Wheeler, G N, Parker, A E, Thomas, C L, Ataliotis, P, Poynter, D, Arnemann, J, Rutman, A J, Pidsley, S C, Watt, F M and Rees, D A (1991) Desmosomal glycoprotein DGI, a component of intercellular desmosome junctions, is related to the cadherin family of cell adhesion molecules. Proceedings of the National Academy of Sciences, 88 (11). pp. 4796-4800. ISSN 0027-8424

Brown, J C, Spragg, J H, Wheeler, G N and Taylor, P W (1990) Identification of the B1 and B2 subunits of human placental laminin and rat parietal-yolk-sac laminin using antisera specific for murine laminin-beta-galactosidase fusion proteins. Biochemical Journal, 270 (2). pp. 463-468. ISSN 0264-6021

Book Section

Wheeler, GN, Field, RA and Tomlinson, ML (2012) Phenotypic screens with model organisms. In: Chemical Genomics. Cambridge University Press, New York, pp. 121-136. ISBN 978-0521889483

Munsterberg, A. and Wheeler, G.N (2005) Cell movements during early vertebrate morphogenesis. In: Cell Signalling and Growth Factors in Development. Wiley, pp. 107-140. ISBN 3-527-31034-7

This list was generated on Tue Oct 19 16:13:20 2021 BST.