Matrix metalloproteinase genes in Xenopus development

Harrison, Michael, Abu-Elmagd, Muhammad, Grocott, Timothy ORCID:, Yates, Clara, Gavrilovic, Jelena ORCID: and Wheeler, Grant N. ORCID: (2004) Matrix metalloproteinase genes in Xenopus development. Developmental Dynamics, 231 (1). pp. 214-220. ISSN 1058-8388

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Matrix metalloproteinases (MMPs) are a large family of proteins in vertebrates, consisting of over 24 genes in humans, only a few of which have been identified in Xenopus. Three genes coding for MMPs in Xenopus have been identified and their expression studied during development. The membrane-bound XMMP-14 and -15 (XMT1-MMP and XMT2-MMP) both showed restricted expression patterns, the former principally localising to cranial neural crest tissues and the latter to the epidermis of the embryo. XMMP-7 codes for an MMP that lacks the hemopexin-like domain. It is expressed exclusively in macrophages or other myeloid cell types from early in development.

Item Type: Article
Additional Information: mid:13168 dc:ueastatus:post-print formatted dc:ueahesastaffidentifier:9411720000424 dc:uearesearchgroup:Pharmacy Practice
Faculty \ School:

Faculty of Science > School of Biological Sciences
Depositing User: Pure Connector
Date Deposited: 10 Jul 2013 08:46
Last Modified: 07 Mar 2023 12:30
DOI: 10.1002/dvdy.v231:1

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