Items where Research Group is "Synthetic and Medicinal Chemistry

A

Arbaoui, Abdessamad, Redshaw, Carl, Homden, Damien M., Wright, Joseph A. and Elsegood, Mark R. J. (2009) Vanadium-based imido-alkoxide pro-catalysts bearing bisphenolate ligands for ethylene and ε-caprolactone polymerisation. Dalton Transactions (41). pp. 8911-8922. ISSN 1477-9226

B

Bernlind, Christian, Homans, Steven W. and Field, Robert A. (2009) Synthesis of prospective disaccharide ligands for Escherichia coli O157 verotoxin. Tetrahedron Letters, 50 (26). pp. 3397-3399. ISSN 0040-4039

Bew, S. P., Fairhurst, S., Hughes, D. L., Legentil, L., Liddle, J., Pesce, P., Nigudkar, S. and Wilson, M. A. (2009) Fluoronium Organocatalysis. Synfacts, 2009 (12). p. 1406. ISSN 1861-1958

Bew, S.P., Fairhurst, S.A., Hughes, David, Legentil, L., Liddle, J., Pesce, P., Nigudkar, S. and Wilson, M.A. (2009) Organocatalytic aziridine synthesis using F salts. Organic Letters, 11 (20). pp. 4552-4555. ISSN 1523-7052

Bew, SP and Pesce, P (2009) Organocatalytic synthesis of aziridines. In: 238th ACS National Meeting, 2009-08-16 - 2009-08-20.

Bew, SP and Sharma, S (2009) Synthesis of tyrosine based calix[4]arenes. In: 238th ACS National Meeting, 2009-08-16 - 2009-08-20.

Bew, Sean P., Brimage, Rebecca A., Hiatt-Gipson, Glyn, Sharma, Sunil V. and Thurston, Sean (2009) Hybrid calix[4]arenes via ionic hydrogenation and transition-metal-mediated processes. Organic Letters, 11 (12). pp. 2483-2486. ISSN 1523-7052

Bew, Sean P., Carrington, Rachel, Hughes, David L., Liddle, John and Pesce, Paolo (2009) An organocatalytic synthesis of cis-N-alkyl- and N-arylaziridine carboxylates. Advanced Synthesis & Catalysis, 351 (16). pp. 2579-2588. ISSN 1615-4150

Bew, Sean P., Cheesman, Myles R. and Sharma, Sunil V. (2009) Ferrocenium salts mediate para-tert-butylcalixarene synthesis. ChemInform, 40 (13). ISSN 1522-2667

Broomfield, Lewis M., Boschert, David, Wright, Joseph A., Hughes, David L. and Bochmann, Manfred (2009) Synthesis of neutral and zwitterionic phosphinomethylpyrrolato complexes of nickel. Journal of Organometallic Chemistry, 694 (25). pp. 4084-4089.

Broomfield, Lewis M., Wright, Joseph A. and Bochmann, Manfred (2009) Synthesis, structures and reactivity of 2-phosphorylmethyl-1H-pyrrolato complexes of titanium, yttrium and zinc. Dalton Transactions (39). pp. 8269-8279. ISSN 1477-9234

C

Cammidge, Andrew N., Chausson, Céline, Gopee, Hemant, Li, Juanjuan and Hughes, David L. (2009) Probing the structural factors influencing columnar mesophase formation and stability in triphenylene discotics. Chemical Communications (47). pp. 7375-7377. ISSN 1359-7345

Cammidge, Andrew N., Goddard, Victoria H. M., Will, Geoffrey, Arnold, Dennis P. and Cook, Michael J. (2009) Mixed cyclisations giving phthalocyanine–naphthalocyanine hybrids. Tetrahedron Letters, 50 (25). pp. 3013-3016.

Cammidge, Andrew N. and Gopee, Hemant (2009) Synthesis and properties of macrodiscotic triphenylenophthalocyanines. Journal of Porphyrins and Phthalocyanines, 13 (2). pp. 235-246. ISSN 1088-4246

Cammidge, Andrew N. and Gopee, Hemant (2009) Synthesis and properties of mixed alkynyl-alkoxy-triphenylenes. Liquid Crystals, 36 (7). pp. 809-816. ISSN 0267-8292

Cammidge, Andrew N., Gopee, Hemant and Patel, Hitesh (2009) Synthesis and characterisation of novel hexaalkoxytriphenylenes bearing an additional alkyl chain in the α-position. Tetrahedron Letters, 50 (26). pp. 3513-3515.

Cammidge, Andrew N., Tseng, Chiung-Hui, Chambrier, Isabelle, Hughes, David L. and Cook, Michael J. (2009) Phthalocyanines bearing bulky cycloalkylmethyl substituents on non-peripheral sites. Tetrahedron Letters, 50 (37). pp. 5254-5256.

Caravano, Audrey, Field, Robert A., Percy, Jonathan M., Rinaudo, Giuseppe, Roig, Ricard and Singh, Kuldip (2009) Developing an asymmetric, stereodivergent route to selected 6-deoxy-6-fluoro-hexoses. Organic and Biomolecular Chemistry, 7 (5). pp. 996-1008. ISSN 1477-0520

Chessa, Simona, Clayden, Nigel J., Bochmann, Manfred and Wright, Joseph A. (2009) α-Zirconium phosphonates: versatile supports for N-heterocyclic carbenes. Chemical Communications (7). pp. 797-799. ISSN 1364-548X

Clark, Ryan C., Lee, Sang Yeul, Hwang, Inkyu, Searcey, Mark and Boger, Dale L. (2009) Evaluation of chlorofusin, its seven chromophore diastereomers, and key analogues. Tetrahedron Letters, 50 (26). pp. 3151-3153.

Clark, Ryan C., Lee, Sang Yeul, Searcey, Mark and Boger, Dale L. (2009) The isolation, total synthesis and structure elucidation of chlorofusin, a natural product inhibitor of the p53–MDM2 protein–protein interaction. Natural Product Reports, 26 (4). pp. 465-477. ISSN 1460-4752

Collingwood, S., Lock, R. and Searcey, Mark (2009) Optimizing drugs for local delivery. Drug News & Perspectives, 22 (10). pp. 627-634. ISSN 0214-0934

D

Dawson, S., Searcey, M., Hampshire, A., Fox, K. and Malkinson, J. (2009) Solid-phase-based synthesis and biological evaluation of novel chromophore analogues of the bis-intercalator TANDEM. Biopolymers, 92 (4). p. 367. ISSN 0006-3525

E

Errey, James C., Mann, Maretta C., Fairhurst, Shirley A., Hill, Lionel, McNeil, Michael R., Naismith, James H., Percy, Jonathan M., Whitfield, Chris and Field, Robert A. (2009) Sugar nucleotide recognition by Klebsiella pneumoniae UDP-d-galactopyranose mutase:Fluorinated substrates, kinetics and equilibria. Organic and Biomolecular Chemistry, 7 (5). pp. 1009-1016. ISSN 1477-0520

F

Field, Robert A. (2009) Oligosaccharide signalling molecules. In: Plant-derived Natural Products. Springer, pp. 349-359. ISBN 9780387854977

G

Ghosh, Nandita, Sheldrake, Helen M., Searcey, Mark and Pors, Klaus (2009) Chemical and biological explorations of the family of CC-1065 and the duocarmycin natural products. Current Topics in Medicinal Chemistry, 9 (16). pp. 1494-1524. ISSN 1568-0266

Gibson, Darren, Homans, Steven W. and Field, Robert A. (2009) A sugar aminoacid for the development of multivalent ligands for Escherichia coli 0157 verotoxin. Tetrahedron Asymmetry, 20 (6-8). pp. 730-732. ISSN 0957-4166

H

Homden, Damien, Redshaw, Carl, Warford, Lee, Hughes, David L., Wright, Joseph A, Dale, Sophie H. and Elsegood, Mark R. J. (2009) Synthesis, structure and ethylene polymerisation behaviour of vanadium(IV and V) complexes bearing chelating aryloxides. Dalton Transactions (41). pp. 8900-8910. ISSN 1477-9234

Howard, Ruth H., Alonso-Moreno, Carlos, Broomfield, Lewis M., Hughes, David L., Wright, Joseph A. and Bochmann, Manfred (2009) Synthesis and structures of complexes with axially chiral isoquinolinyl-naphtholate ligands. Dalton Transactions (40). pp. 8667-8682. ISSN 1477-9234

Howell, L. A. and Searcey, Mark (2009) Targeting the Holliday junction: Design and synthesis of acridine-3/4-carboxamide analogs using click chemistry. Abstracts of Papers of the American Chemical Society, 238. 210-ORGN. ISSN 0065-7727

Howell, Lesley, Howman, Aaron, O'Connell, Maria, Mueller, Anja and Searcey, Mark (2009) Synthesis and evaluation of 9-aminoacridines derived from benzyne click chemistry. Bioorganic & Medicinal Chemistry Letters, 19 (20). pp. 5880-5883. ISSN 1464-3405

Howell, Lesley and Searcey, Mark (2009) Targeting higher-order DNA: Beyond the G-quadruplex. ChemBioChem, 10 (13). pp. 2139-2143. ISSN 1439-7633

M

Mikhailova, L. R., Baltina, L. A., Baltina, L. A., Kondratenko, R. M., Nepogodiev, S. A., Field, R. A., Kunert, O. and Yin, M. C. (2009) A simple method of synthesis of triterpene glycosides similar to glycyrrhizic acid and their hepatoprotective activity in vitro. Bioorganicheskaia khimiia, 35 (5). pp. 686-695. ISSN 0132-3423

Mukhopadhyay, Balaram, Martins, Maristela B., Karamanska, Rositsa, Russell, David A. and Field, Robert A. (2009) Bacterial detection using carbohydrate-functionalised CdS quantum dots: a model study exploiting E. coli recognition of mannosides. Tetrahedron Letters, 50 (8). pp. 886-889.

N

Newton, Gerald L., Rawat, Mamta, La Clair, James J., Jothivasan, Vishnu Karthik, Budiarto, Tanya, Hamilton, Chris J., Claiborne, Al, Helmann, John D. and Fahey, Robert C. (2009) Bacillithiol is an antioxidant thiol produced in Bacilli. Nature Chemical Biology, 5 (9). pp. 625-627. ISSN 1552-4450

O

Oganesyan, V. S., Kuprusevicius, E., Gopee, H., Cammidge, A. N. and Wilson, M. R. (2009) Electron paramagnetic resonance spectra simulation directly from molecular dynamics trajectories of a liquid crystal with a doped paramagnetic spin probe. Physical Review Letters, 102 (1). ISSN 0031-9007

R

Redshaw, Carl, Homden, Damien, Hughes, David L., Wright, Joseph A. and Elsegood, Mark R. J. (2009) New structural motifs in chromium(III) calix[4 and 6]arene chemistry. Dalton Transactions (7). pp. 1231-1242. ISSN 1477-9234

Rejzek, Martin, Kannathasan, Velupillai Sri, Wing, Corin, Preston, Andrew, Westman, Erin L., Lam, Joseph S., Naismith, James H., Maskell, Duncan J. and Field, Robert A. (2009) Chemical synthesis of UDP-Glc-2,3-diNAcA, a key intermediate in cell surface polysaccharide biosynthesis in the human respiratory pathogens B. pertussis and P. aeruginosa. Organic and Biomolecular Chemistry, 7 (6). pp. 1203-1210. ISSN 1477-0520

Rowan, Andrew S., Nicely, Nathan I., Cochrane, Nicola, Wlassoff, Wjatschesslaw A., Claiborne, Al and Hamilton, Chris J. (2009) Nucleoside triphosphate mimicry: a sugar triazolyl nucleoside as an ATP-competitive inhibitor of B. anthracis pantothenate kinase. Organic & Biomolecular Chemistry, 7 (19). pp. 4029-4036. ISSN 1477-0520

Roy, Bimalendu, Field, Robert A. and Mukhopadhyay, Balaram (2009) Synthesis of a tetrasaccharide related to the repeating unit of the O-antigen from Escherichia coli K-12. Carbohydrate Research, 344 (17). pp. 2311-2316. ISSN 0008-6215

S

Shaginian, Alex, Whitby, Landon R., Hong, Sukwon, Hwang, Inkyu, Farooqi, Bilal, Searcey, Mark, Chen, Jiandong, Vogt, Peter K. and Boger, Dale L. (2009) Design, synthesis, and evaluation of an a-helix mimetic library targeting protein-protein interactions. Journal of the American Chemical Society, 131 (15). pp. 5564-5572. ISSN 1520-5126

Sharma, S. and Bew, S. P. (2009) Capsule formation using upper-rim appended bis-1,3-urea calix[4]arenes. In: 238th ACS National Meeting, 2009-08-16 - 2009-08-20.

Stewart, Matthew J. G., Jothivasan, Vishnu Karthik, Rowan, Andrew S., Wagg, Jennifer and Hamilton, Chris J. (2009) Mycothiol disulfide reductase: solid phase synthesis and evaluation of alternative substrate analogues. Organic & Biomolecular Chemistry, 6 (2). pp. 385-390. ISSN 1477-0520

T

Tomlinson, Mark L., Guan, Pingping, Morris, Richard J., Fidock, Mark D., Rejzek, Martin, Garcia Morales, Carla, Field, Robert A. and Wheeler, Grant N. (2009) A chemical genomic approach identifies matrix metalloptroteinases as playing an essential and specific role in Xenopus melanophore migration. Chemistry and Biology, 16 (1). pp. 93-104. ISSN 1879-1301

Tomlinson, Matthew L., Rejzek, Martin, Fidock, Mark, Field, Robert A. and Wheeler, Grant N. (2009) Chemical genomics identifies compounds affecting Xenopus laevis pigment cell development. Molecular BioSystems, 5 (4). pp. 376-384.

W

Wagner, Gerd K., Pesnot, Thomas and Field, Robert A. (2009) A survey of chemical methods for sugar-nucleotide synthesis. Natural Product Reports, 26 (9). pp. 1172-1194. ISSN 0265-0568

Watanabe, Kenji, Hotta, Kinya, Praseuth, Alex P., Searcey, Mark, Wang, Clay C. C., Oguri, Hiroki and Oikawa, Hideaki (2009) Rationally engineered total biosynthesis of a synthetic analogue of a natural quinomycin depsipeptide in Escherichia coli. ChemBioChem, 10 (12). pp. 1965-1968. ISSN 1439-7633

Westman, Erin L., McNally, David J., Charchoglyan, Armen, Brewer, Dyanne, Field, Robert A. and Lam, Joseph S. (2009) Characterization of WbpB, WbpE, and WbpD and reconstitution of a pathway for the biosynthesis of UDP-2,3-diacetamido-2,3-dideoxy-D-mannuronic acid in Pseudomonas aeruginosa. Journal of Biological Chemistry, 284 (18). pp. 11854-11862. ISSN 0021-9258

Wright, Joseph A and Pickett, Christopher J (2009) Protonation of a subsite analogue of [FeFe]-hydrogenase: mechanism of a deceptively simple reaction revealed by time-resolved IR spectroscopy. Chemical Communications (38). pp. 5719-5721. ISSN 1364-548X

Z

Zhao, Zhixin, Cammidge, Andrew N. and Cook, Michael J. (2009) Towards black chromophores: mu-oxo linked phthalocyanine-porphyrin dyads and phthalocyanine-subphthalocyanine dyad and triad arrays. Chemical Communications (48). pp. 7530-7532. ISSN 1364-548X