A sugar aminoacid for the development of multivalent ligands for Escherichia coli 0157 verotoxin

Gibson, Darren, Homans, Steven W. and Field, Robert A. ORCID: https://orcid.org/0000-0001-8574-0275 (2009) A sugar aminoacid for the development of multivalent ligands for Escherichia coli 0157 verotoxin. Tetrahedron Asymmetry, 20 (6-8). pp. 730-732. ISSN 0957-4166

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Abstract

Functionalised carbohydrates for incorporation into multivalent ligands for the Escherichia coli 0157 verotoxin are highly desirable. Here, we report the synthesis of a sugar aminoacid based on the known Gal-α-1,4-Gal ligand for verotoxin in eight steps and in ∼10% overall yield.

Item Type:	Article
Additional Information:	Funding Information: These studies were supported by the BBSRC. We thank the EPSRC National Mass Spectrometry Service Centre, Swansea, for invaluable support.
Uncontrolled Keywords:	catalysis,physical and theoretical chemistry,organic chemistry,inorganic chemistry ,/dk/atira/pure/subjectarea/asjc/1500/1503
Faculty \ School:	Faculty of Science > School of Chemistry, Pharmacy and Pharmacology Faculty of Science > School of Biological Sciences
UEA Research Groups:	Faculty of Science > Research Groups > Synthetic and Medicinal Chemistry
Related URLs:	https://www.scopus.com/pages/publication...
Depositing User:	LivePure Connector
Date Deposited:	06 Sep 2024 13:35
Last Modified:	18 Jun 2026 20:20
URI:	https://ueaeprints.uea.ac.uk/id/eprint/96598
DOI:	10.1016/j.tetasy.2009.02.021

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