Synthesis of a tetrasaccharide related to the repeating unit of the O-antigen from Escherichia coli K-12

Roy, Bimalendu, Field, Robert A. ORCID: https://orcid.org/0000-0001-8574-0275 and Mukhopadhyay, Balaram (2009) Synthesis of a tetrasaccharide related to the repeating unit of the O-antigen from Escherichia coli K-12. Carbohydrate Research, 344 (17). pp. 2311-2316. ISSN 0008-6215

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Abstract

Synthesis of a tetrasaccharide related to the repeating unit of the O-antigen from Escherichia coli K-12 is reported in the form of its octyl glycoside. Syntheses of the 1,2-cis glycosidic linkages have been accomplished by using NIS in conjunction with H2SO4-silica, and it was found to be stereoselective and productive. The synthesized tetrasaccharide will be utilized as the substrate for galactofuranosyltransferase, WbbI.

Item Type: Article
Additional Information: Funding Information: B.R. is thankful to the Council of Scientific and Industrial Research (CSIR), New Delhi, India, for a fellowship. The work is funded by the Department of Science and Technology (DST), New Delhi, India through a SERC Fast-Track Grant SR/FTP/CS-110/2005.
Uncontrolled Keywords: 1,2-cis glycosylation,bacterial oligosaccharide,hso-silica,analytical chemistry,biochemistry,organic chemistry ,/dk/atira/pure/subjectarea/asjc/1600/1602
Faculty \ School:
Faculty of Science > School of Chemistry, Pharmacy and Pharmacology
Faculty of Science > School of Biological Sciences
Related URLs:
Depositing User: LivePure Connector
Date Deposited: 06 Sep 2024 13:34
Last Modified: 25 Sep 2024 18:07
URI: https://ueaeprints.uea.ac.uk/id/eprint/96595
DOI: 10.1016/j.carres.2009.09.026

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