Items where Author is "Horwood, Nicole"

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Regan-Komito, Daniel, Swann, James W., Demetriou, Philippos, Cohen, E. Suzanne, Horwood, Nicole J., Sansom, Stephen N. and Griseri, Thibault (2020) GM-CSF drives dysregulated hematopoietic stem cell activity and pathogenic extramedullary myelopoiesis in experimental spondyloarthritis. Nature Communications, 11 (1). ISSN 2041-1723

Lee, Geoffrey, Espirito Santo, Ana Isabel, Zwingenberger, Stefan, Cai, Lawrence, Vogl, Thomas, Feldmann, Marc, Horwood, Nicole J, Chan, James K and Nanchahal, Jagdeep (2018) Fully reduced HMGB1 accelerates the regeneration of multiple tissues by transitioning stem cells to G. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 115 (19). E4463-E4472. ISSN 1091-6490

Page, Theresa H, Urbaniak, Anna M, Espirito Santo, Ana I, Danks, Lynett, Smallie, Timothy, Williams, Lynn M and Horwood, Nicole J (2018) Bruton's tyrosine kinase regulates TLR7/8-induced TNF transcription via nuclear factor-κB recruitment. Biochemical and Biophysical Research Communications, 499 (2). pp. 260-266. ISSN 0006-291X

Ersek, Adel, Santo, Ana I. Espirito, Vattakuzhi, Youridies, George, Saumya, Clark, Andrew R. and Horwood, Nicole J. (2016) Strain dependent differences in glucocorticoid-induced bone loss between C57BL/6J and CD-1 mice. Scientific Reports, 6. ISSN 2045-2322

Horwood, Nicole J (2016) Macrophage Polarization and Bone Formation:A review. Clinical Reviews in Allergy & Immunology, 51 (1). pp. 79-86. ISSN 1080-0549

Santo, A. I. Espirito, Ersek, A., Freidin, A., Feldmann, M., Stoop, A. A. and Horwood, N. J. (2015) Selective inhibition of TNFR1 reduces osteoclast numbers and is differentiated from anti-TNF in a LPS-driven model of inflammatory bone loss. Biochemical and Biophysical Research Communications, 464 (4). pp. 1145-1150. ISSN 0006-291X

Ersek, Adel, Xu, Ke, Antonopoulos, Aristotelis, Butters, Terry D, Santo, Ana Espirito, Vattakuzhi, Youridies, Williams, Lynn M, Goudevenou, Katerina, Danks, Lynett, Freidin, Andrew, Spanoudakis, Emmanouil, Parry, Simon, Papaioannou, Maria, Hatjiharissi, Evdoxia, Chaidos, Aristeidis, Alonzi, Dominic S, Twigg, Gabriele, Hu, Ming, Dwek, Raymond A, Haslam, Stuart M, Roberts, Irene, Dell, Anne, Rahemtulla, Amin, Horwood, Nicole J and Karadimitris, Anastasios (2015) Glycosphingolipid synthesis inhibition limits osteoclast activation and myeloma bone disease. Journal of Clinical Investigation, 125 (6). pp. 2279-2292. ISSN 0021-9738

Chan, James K, Glass, Graeme E, Ersek, Adel, Freidin, Andrew, Williams, Garry A, Gowers, Kate, Espirito Santo, Ana I, Jeffery, Rosemary, Otto, William R, Poulsom, Richard, Feldmann, Marc, Rankin, Sara M, Horwood, Nicole J and Nanchahal, Jagdeep (2015) Low-dose TNF augments fracture healing in normal and osteoporotic bone by up-regulating the innate immune response. EMBO Molecular Medicine, 7 (5). pp. 547-561. ISSN 1757-4676

Newman, Simon D, Lotfibakhshaiesh, Nasrin, O'Donnell, Matthew, Walboomers, X Frank, Horwood, Nicole, Jansen, John A, Amis, Andrew A, Cobb, Justin P and Stevens, Molly M (2014) Enhanced osseous implant fixation with strontium-substituted bioactive glass coating. Tissue engineering. Part A, 20 (13-14). pp. 1850-1857. ISSN 1937-335X

Santo, A. I. Espirito, Chan, J. K., Glass, G. E., Ersek, A., Williams, G. A., Freidin, A., Gowers, K., Jeffery, R., Otto, W. R., Poulsom, R., Feldmann, M., Rankin, S. M., Horwood, N. J. and Nanchahal, J. (2014) Enhancement of fracture repair by upregulation of the innate immune response. European Journal of Clinical Investigation, 44. pp. 30-31. ISSN 0014-2972

Gwyer Findlay, Emily, Danks, Lynett, Madden, Jodie, Cavanagh, Mary M, McNamee, Kay, McCann, Fiona, Snelgrove, Robert J, Shaw, Stevan, Feldmann, Marc, Taylor, Peter Charles, Horwood, Nicole J and Hussell, Tracy (2014) OX40L blockade is therapeutic in arthritis, despite promoting osteoclastogenesis. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 111 (6). pp. 2289-2294. ISSN 1091-6490

Jones, Gemma N, Moschidou, Dafni, Abdulrazzak, Hassan, Kalirai, Bhalraj Singh, Vanleene, Maximilien, Osatis, Suchaya, Shefelbine, Sandra J, Horwood, Nicole J, Marenzana, Massimo, De Coppi, Paolo, Bassett, J H Duncan, Williams, Graham R, Fisk, Nicholas M and Guillot, Pascale V (2014) Potential of human fetal chorionic stem cells for the treatment of osteogenesis imperfecta. Stem Cells and Development, 23 (3). pp. 262-276. ISSN 1547-3287

Wythe, Sarah E, Nicolaidou, Vicky and Horwood, Nicole J (2014) Cells of the immune system orchestrate changes in bone cell function. Calcified Tissue International, 94 (1). pp. 98-111. ISSN 0171-967X

Horwood, Nicole J (2013) Immune cells and bone:coupling goes both ways. Immunological Investigations, 42 (7). pp. 532-543. ISSN 0882-0139

Chan, J. K., Glass, G. E., Ersek, A., Williams, G. A., Freidin, A., Gowers, K., Jeffery, R., Otto, W. R., Poulsom, R., Feldmann, M., Rankin, S. M., Horwood, N. J. and Nanchahal, J. (2013) Harnessing the innate immune system to accelerate fracture healing in osteoporotic mice. European Journal of Clinical Investigation, 43. p. 34. ISSN 0014-2972

Ersek, Adel, Karadimitris, Anastasios and Horwood, Nicole J (2012) Effect of glycosphingolipids on osteoclastogenesis and osteolytic bone diseases. Frontiers in Endocrinology, 3. pp. 1-7. ISSN 1664-2392

Chan, James K, Roth, Johannes, Oppenheim, Joost J, Tracey, Kevin J, Vogl, Thomas, Feldmann, Marc, Horwood, Nicole and Nanchahal, Jagdeep (2012) Alarmins:awaiting a clinical response. Journal of Clinical Investigation, 122 (8). pp. 2711-2719. ISSN 0021-9738

Nicolaidou, Vicky, Wong, Mei Mei, Redpath, Andia N, Ersek, Adel, Baban, Dilair F, Williams, Lynn M, Cope, Andrew P and Horwood, Nicole J (2012) Monocytes induce STAT3 activation in human mesenchymal stem cells to promote osteoblast formation. PLoS One, 7 (7). ISSN 1932-6203

Vattakuzhi, Youridies, Abraham, Sonya M, Freidin, Andrew, Clark, Andrew R and Horwood, Nicole J (2012) Dual-specificity phosphatase 1-null mice exhibit spontaneous osteolytic disease and enhanced inflammatory osteolysis in experimental arthritis. Arthritis and Rheumatism, 64 (7). pp. 2201-2210. ISSN 0004-3591

Horwood, Nicole J, Urbaniak, Ania M and Danks, Lynett (2012) Tec family kinases in inflammation and disease. Molecular Immunology, 31 (2). pp. 87-103. ISSN 0161-5890

Smolinska, Maria J, Page, Theresa H, Urbaniak, Ania M, Mutch, Brenda E and Horwood, Nicole J (2011) Hck tyrosine kinase regulates TLR4-induced TNF and IL-6 production via AP-1. Journal of Immunology, 187 (11). pp. 6043-6051. ISSN 0022-1767

Hu, Ming, Bassett, J H Duncan, Danks, Lynett, Howell, Peter G T, Xu, Ke, Spanoudakis, Emmanouil, Kotsianidis, Ioannis, Boyde, Alan, Williams, Graham R, Horwood, Nikki, Roberts, Irene A G and Karadimitris, Anastasios (2011) Activated invariant NKT cells regulate osteoclast development and function. Journal of Immunology, 186 (5). pp. 2910-2917. ISSN 0022-1767

Pöllinger, Bernadette, Junt, Tobias, Metzler, Barbara, Walker, Ulrich A, Tyndall, Alan, Allard, Cyril, Bay, Serkan, Keller, Roland, Raulf, Friedrich, Di Padova, Franco, O'Reilly, Terrence, Horwood, Nicole J, Patel, Dhavalkumar D and Littlewood-Evans, Amanda (2011) Th17 cells, not IL-17+ γδ T cells, drive arthritic bone destruction in mice and humans. Journal of Immunology, 186 (4). pp. 2602-2612. ISSN 0022-1767

Lymperi, Stefania, Ersek, Adel, Ferraro, Francesca, Dazzi, Francesco and Horwood, Nicole J (2011) Inhibition of osteoclast function reduces hematopoietic stem cell numbers in vivo. Blood, 117 (5). pp. 1540-1549. ISSN 0006-4971

Glass, Graeme E, Chan, James K, Freidin, Andrew, Feldmann, Marc, Horwood, Nicole J and Nanchahal, Jagdeep (2011) TNF-alpha promotes fracture repair by augmenting the recruitment and differentiation of muscle-derived stromal cells. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 108 (4). pp. 1585-1590. ISSN 1091-6490

Danks, Lynett, Workman, Sarita, Webster, David and Horwood, Nicole J (2011) Elevated cytokine production restores bone resorption by human Btk-deficient osteoclasts. Journal of Bone and Mineral Research, 26 (1). pp. 182-192. ISSN 0884-0431

Smallie, Tim, Ricchetti, Giuseppe, Horwood, Nicole J, Feldmann, Marc, Clark, Andrew R and Williams, Lynn M (2010) IL-10 inhibits transcription elongation of the human TNF gene in primary macrophages. Journal of Experimental Medicine, 207 (10). pp. 2081-2088. ISSN 0022-1007

Van den Eynden, Jimmy, Ali, Sheen Saheb, Horwood, Nikki, Carmans, Sofie, Brône, Bert, Hellings, Niels, Steels, Paul, Harvey, Robert J and Rigo, Jean-Michel (2009) Glycine and glycine receptor signalling in non-neuronal cells. Frontiers in Molecular Neuroscience, 2. pp. 1-12. ISSN 1662-5099

Gingery, Anne, Bradley, Elizabeth W, Pederson, Larry, Ruan, Ming, Horwood, Nikki J. and Oursler, Merry Jo (2008) TGF-β coordinately activates TAK1/MEK/AKT/NFkB and SMAD pathways to promote osteoclast survival. Experimental Cell Research, 314 (15). pp. 2725-2738. ISSN 0014-4827

Palmer, Christine D, Mutch, Brenda E, Page, Theresa H, Horwood, Nicole J and Foxwell, Brian M J (2008) Bmx regulates LPS-induced IL-6 and VEGF production via mRNA stability in rheumatoid synovial fibroblasts. Biochemical and Biophysical Research Communications, 370 (4). pp. 599-602. ISSN 0006-291X

Horwood, Nicole (2008) Lymphocyte-derived cytokines in inflammatory arthritis. Autoimmunity, 41 (3). pp. 230-238. ISSN 0891-6934

Palmer, Christine D, Mutch, Brenda E, Workman, Sarita, McDaid, John P, Horwood, Nicole J and Foxwell, Brian M J (2008) Bmx tyrosine kinase regulates TLR4-induced IL-6 production in human macrophages independently of p38 MAPK and NFkapp}B activity. Blood, 111 (4). pp. 1781-1788. ISSN 0006-4971

Lymperi, Stefania, Horwood, Nicole, Marley, Stephen, Gordon, Myrtle Y, Cope, Andrew P and Dazzi, Francesco (2008) Strontium can increase some osteoblasts without increasing hematopoietic stem cells. Blood, 111 (3). pp. 1173-1181. ISSN 0006-4971

Smolinska, Maria J, Horwood, Nicole J, Page, Theresa H, Smallie, Tim and Foxwell, Brian M J (2008) Chemical inhibition of Src family kinases affects major LPS-activated pathways in primary human macrophages. Molecular Immunology, 45 (4). pp. 990-1000. ISSN 0161-5890

Zaiss, Mario M, Axmann, Roland, Zwerina, Jochen, Polzer, Karin, Gückel, Eva, Skapenko, Alla, Schulze-Koops, Hendrik, Horwood, Nikki, Cope, Andrew and Schett, Georg (2007) Treg cells suppress osteoclast formation:a new link between the immune system and bone. Arthritis and Rheumatism, 56 (12). pp. 4104-4112. ISSN 0004-3591

Dazzi, Francesco and Horwood, Nicole J (2007) Potential of mesenchymal stem cell therapy. Current Opinion in Oncology, 19 (6). pp. 650-655. ISSN 1040-8746

Jones, Simon, Horwood, Nicole, Cope, Andrew and Dazzi, Francesco (2007) The antiproliferative effect of mesenchymal stem cells is a fundamental property shared by all stromal cells. Journal of Immunology, 179 (5). pp. 2824-2831. ISSN 0022-1767

Horwood, Nicole J, Page, Theresa H, McDaid, John P, Palmer, Christine D, Campbell, Jamie, Mahon, Tara, Brennan, Fionula M, Webster, David and Foxwell, Brian M J (2006) Bruton's tyrosine kinase is required for TLR2 and TLR4-induced TNF, but not IL-6, production. Journal of Immunology, 176 (6). pp. 3635-3641. ISSN 0022-1767

Campbell, Jamie, Ciesielski, Cathleen J, Hunt, Abigail E, Horwood, Nicole J, Beech, Jonathan T, Hayes, Louise A, Denys, Agnes, Feldmann, Marc, Brennan, Fionula M and Foxwell, Brian M J (2004) A novel mechanism for TNF-alpha regulation by p38 MAPK:involvement of NF-kappa B with implications for therapy in rheumatoid arthritis. Journal of Immunology, 173 (11). pp. 6928-6937. ISSN 0022-1767

Häusler, Karl D, Horwood, Nicole J, Chuman, Yoshiro, Fisher, Jane L, Ellis, Jennifer, Martin, T John, Rubin, Jeffrey S and Gillespie, Matthew T (2004) Secreted frizzled-related protein-1 inhibits RANKL-dependent osteoclast formation. Journal of Bone and Mineral Research, 19 (11). pp. 1873-1881. ISSN 0884-0431

Horwood, Nicole J, Mahon, Tara, McDaid, John P, Campbell, Jamie, Mano, Hiroyuki, Brennan, Fionula M, Webster, David and Foxwell, Brian M J (2003) Bruton's tyrosine kinase is required for lipopolysaccharide-induced tumor necrosis factor alpha production. Journal of Experimental Medicine, 197 (12). pp. 1603-1611. ISSN 0022-1007

Mirosavljevic, Danijela, Quinn, Julian M W, Elliott, Jan, Horwood, Nicole J, Martin, T John and Gillespie, Matthew T (2003) T-cells mediate an inhibitory effect of interleukin-4 on osteoclastogenesis. Journal of Bone and Mineral Research, 18 (6). pp. 984-993. ISSN 0884-0431

Cornish, J, Gillespie, M T, Callon, K E, Horwood, N J, Moseley, J M and Reid, I R (2003) Interleukin-18 is a novel mitogen of osteogenic and chondrogenic cells. Endocrinology, 144 (4). pp. 1194-1201. ISSN 0013-7227

Feldmann, M, Andreakos, E, Smith, C, Bondeson, J, Yoshimura, S, Kiriakidis, S, Monaco, C, Gasparini, C, Sacre, S, Lundberg, A, Paleolog, E, Horwood, N J, Brennan, F M and Foxwell, B M J (2002) Is NF-kappaB a useful therapeutic target in rheumatoid arthritis? Annals of the Rheumatic Diseases, 61 (Suppl 2). ii13-ii18. ISSN 0003-4967

Horwood, Nicole J, Smith, Clive, Andreakos, Evangelos, Quattrocchi, Emilia, Brennan, Fionula M, Feldmann, Marc and Foxwell, Brian M J (2002) High-efficiency gene transfer into nontransformed cells:utility for studying gene regulation and analysis of potential therapeutic targets. Arthritis Research, 4 (3). pp. 215-225. ISSN 1465-9905

Horwood, Nicole J., Elliott, Jan, Martin, T. John and Gillespie, Matthew T. (2001) IL-12 alone and in synergy with IL-18 inhibits osteoclast formation in vitro. Journal of Immunology, 166 (8). pp. 4915-4921. ISSN 0022-1767

Quinn, Julian M. W., Horwood, Nicole J., Elliott, Jan, Gillespie, Matthew T. and Martin, T. John (2000) Fibroblastic stromal cells express receptor activator of NF-kappa B ligand and support osteoclast differentiation. Journal of Bone and Mineral Research, 15 (8). pp. 1459-1466. ISSN 0884-0431

Horwood, Nicole J., Kartsogiannis, Vicky, Quinn, Julian M. W., Romas, Evangelos, Martin, T. John and Gillespie, Matthew T. (1999) Activated T lymphocytes support osteoclast formation in vitro. Biochemical and Biophysical Research Communications, 265 (1). pp. 144-150. ISSN 0006-291X

Kartsogiannis, V, Zhou, H, Horwood, N J, Thomas, R J, Hards, D K, Quinn, J M, Niforas, P, Ng, K W, Martin, T J and Gillespie, M T (1999) Localization of RANKL (receptor activator of NF kappa B ligand) mRNA and protein in skeletal and extraskeletal tissues. Bone, 25 (5). pp. 525-534. ISSN 8756-3282

Thomas, Rachel J., Guise, Theresa A., Yin, Juan Juan, Elliott, Jan, Horwood, Nicole J., Martin, T. John and Gillespie, Matthew T. (1999) Breast cancer cells interact with osteoblasts to support osteoclast formation. Endocrinology, 140 (10). pp. 4451-4458. ISSN 0013-7227

Horwood, N J, Elliott, Jan, Martin, T J and Gillespie, M T (1998) Osteotropic agents regulate the expression of osteoclast differentiation factor and osteoprotegerin in osteoblastic stromal cells. Endocrinology, 139 (11). pp. 4743-4746. ISSN 0013-7227

Gillespie, M T and Horwood, N J (1998) Interleukin-18:perspectives on the newest interleukin. Cytokine & Growth Factor Reviews, 9 (2). pp. 109-116. ISSN 1359-6101

Horwood, N J, Udagawa, N, Elliott, J, Grail, D, Okamura, H, Kurimoto, M, Dunn, A R, Martin, T and Gillespie, M T (1998) Interleukin 18 inhibits osteoclast formation via T cell production of granulocyte macrophage colony-stimulating factor. Journal of Clinical Investigation, 101 (3). pp. 595-603. ISSN 0021-9738

Udagawa, Nobuyuki, Horwood, Nicole J., Elliott, Jan, Mackay, Alan, Owens, Jane, Okamura, Haruki, Kurimoto, Masashi, Chambers, Timothy J., Martin, T. John and Gillespie, Matthew T. (1997) Interleukin-18 (interferon-gamma-inducing factor) is produced by osteoblasts and acts via granulocyte/macrophage colony-stimulating factor and not via interferon-gamma to inhibit osteoclast formation. Journal of Experimental Medicine, 185 (6). pp. 1005-1012. ISSN 0022-1007

Conference or Workshop Item

Nicolaidou, V., Afrough, S., Wong, M., Redpath, A. N., Ersek, A., Baban, D. F., Williams, L., Cope, A. and Horwood, N. (2012) Monocytes promote osteogenic differentiation of mesenchymal stem cells via PGE2 and Oncostatin M. In: European Congress of Immunology, 2012-09-05 - 2012-09-08.

Ersek, A., Lymperi, S., Dazzi, F. and Horwood, N. (2011) Osteoclast activity regulates the size of the haematopoietic stem cell pool. In: 3rd Joint Meeting of the European-Calcified-Tissue-Society/International-Bone-and-Mineral-Society, 2011-05-07 - 2011-05-11.

This list was generated on Sun Mar 29 22:53:56 2020 BST.