Interleukin-18:perspectives on the newest interleukin

Gillespie, M T and Horwood, N J (1998) Interleukin-18:perspectives on the newest interleukin. Cytokine & Growth Factor Reviews, 9 (2). pp. 109-116. ISSN 1359-6101

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Abstract

Just over two years ago the newest member of the interleukin family of cytokines, IL-18, was molecularly cloned. IL-18 was originally identified as a result of its ability to induce interferon gamma production, however with the advent of its cloning and the production of recombinant protein a number of other biological actions have since been identified. Recently the receptor for IL-18 was also characterised. Due to the structural and biological properties shared between IL-18 and IL-1 and their respective receptors, questions relating to IL-18 activities are being answered at a rapid pace. This article addresses the biology of IL-18 in both disease and non-disease states.

Item Type: Article
Uncontrolled Keywords: amino acid sequence,animals,autoimmunity,immunology,gene expression,humans,genetics,genetics,interleukin-18 receptor alpha subunit,molecular sequence data,immunology,cytology,physiology,receptors, interleukin-18,immunology
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
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Depositing User: LivePure Connector
Date Deposited: 06 Mar 2019 09:30
Last Modified: 22 Apr 2020 07:34
URI: https://ueaeprints.uea.ac.uk/id/eprint/70114
DOI:

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