Items where Research Group is "Gastroenterology and Gut Biology

A

Abubakar, I. I., Myhill, D. J., Lake, I. R. ORCID: https://orcid.org/0000-0003-4407-5357, Harvey, I. M., Hunter, P. R. ORCID: https://orcid.org/0000-0002-5608-6144 and Hart, A. R. (2005) Crohn's disease: single or multiple pathology? Epidemiological evidence of different phenotypic risk factors. In: 13th United European Gastroenterology Week, 2005-01-01.

Abubakar, I. I., Myhill, D. J., Lake, I. R. ORCID: https://orcid.org/0000-0003-4407-5357, Harvey, I. M., Hunter, P. R. ORCID: https://orcid.org/0000-0002-5608-6144 and Hart, A. R. (2005) Johne's Disease and Admission Rates for Patients Newly Diagnosed with Crohn's Disease in English Counties: An Ecological Study. In: Standing Conference on Water and Health, Health Protection Agency, London, 2005-01-01.

Akashi, Yoshihiro J., Springer, Jochen and Anker, Stefan D. (2005) Cachexia in chronic heart failure: Prognostic implications and novel therapeutic approaches. Current Heart Failure Reports, 2 (4). pp. 198-203. ISSN 1546-9530

Andrew, Elizabeth M and Carding, Simon R (2005) Murine gammadelta T cells in infections: beneficial or deleterious? Microbes and Infection, 7 (3). pp. 529-536. ISSN 1286-4579

Andrew, Elizabeth M., Newton, Darren J., Dalton, Jane E., Egan, Charlotte E., Goodwin, Stewart J., Tramonti, Daniela, Scott, Philip and Carding, Simon R. (2005) Delineation of the function of a major gamma delta T cell subset during infection. Journal of Immunology, 175 (3). pp. 1741-1750. ISSN 0022-1767

Aumailley, Monique, Bruckner-Tuderman, Leena, Carter, William G., Deutzmann, Rainer, Edgar, David, Ekblom, Peter, Engel, Jurgen, Engvall, Eva, Hohenester, Erhard, Jones, Jonathan C. R., Kleinman, Hynda K., Marinkovich, M. Peter, Martin, George R., Mayer, Ulrike ORCID: https://orcid.org/0000-0003-2328-0052, Meneguzzi, Guerrino, Miner, Jeffrey H., Miyazaki, Kaoru, Patarroyo, Manuel, Paulsson, Mats, Quaranta, Vito, Sanes, Joshua R., Sasaki, Takako, Sekiguchi, Kiyotoshi, Sorokin, Lydia M., Talts, Jan F., Tryggvason, Karl, Uitto, Jouni, Virtanen, Ismo, von der Mark, Klaus, Wewer, Ulla M., Yamada, Yoshihiko and Yurchenco, Peter D. (2005) A simplified laminin nomenclature. Matrix Biology, 24 (5). pp. 326-332. ISSN 1569-1802

B

Barratt, H S, Kalantzis, C, Polymeros, D and Forbes, A ORCID: https://orcid.org/0000-0001-7416-9843 (2005) Functional symptoms in inflammatory bowel disease and their potential influence in misclassification of clinical status. Alimentary Pharmacology and Therapeutics, 21 (2). pp. 141-7. ISSN 0269-2813

Beales, I. L. P. (2005) Effects of adiponectin on colonic epithelial cells. In: British Society of Gastroenterology, Birmingham, UK, 2005-01-01.

Beales, I. L. P. (2005) Leptin promotes proliferation and cell survival in colonic epithelial cells. In: British Society of Gastroenterology, Birmingham UK, 2005-01-01.

Beales, I. L. P. and Ogunwobi, O. O. (2005) Glycine-extended gastin stimulates proliferation of oesophageal adenocarcinoma cells via cyclo-oxygenese-2 dependent pathways. Gut, 54 (A100). ISSN 1468-3288

C

Corthésy-Theulaz, Irène, den Dunnen, Johan T, Ferré, Pascal, Geurts, Jan M W, Müller, Michael ORCID: https://orcid.org/0000-0002-5930-9905, van Belzen, Nico and van Ommen, Ben (2005) Nutrigenomics:the impact of biomics technology on nutrition research. Annals of Nutrition & Metabolism, 49 (6). pp. 355-65. ISSN 0250-6807

Croxford, J. Ludovic, Wang, Kegiang, Miller, Stephen D., Engman, David M. and Tyler, Kevin M. ORCID: https://orcid.org/0000-0002-0647-8158 (2005) Effects of cannabinoid treatment on Chagas disease pathogenesis: balancing inhibition of parasite invasion and immunosuppression. Cellular Microbiology, 7 (11). pp. 1592-1602. ISSN 1462-5822

Cruickshank, Sheena M., English, Nicholas R., Felsburg, Peter J. and Carding, Simon R. (2005) Characterization of colonic dendritic cells in normal and colitic mice. World Journal of Gastroenterology, 11 (40). pp. 6338-6347. ISSN 1007-9327

D

Daly, Mark J, Pearce, Alexandra V, Farwell, Lisa, Fisher, Sheila A, Latiano, Anna, Prescott, Natalie J, Forbes, Alastair ORCID: https://orcid.org/0000-0001-7416-9843, Mansfield, John, Sanderson, Jeremy, Langelier, Diane, Cohen, Albert, Bitton, Alain, Wild, Gary, Lewis, Cathryn M, Annese, Vito, Mathew, Christopher G and Rioux, John D (2005) Association of DLG5 R30Q variant with inflammatory bowel disease. European Journal of Human Genetics, 13 (7). pp. 835-9. ISSN 1018-4813

Day, Richard M, Maquet, Véronique, Boccaccini, Aldo R, Jérôme, Robert and Forbes, Alastair ORCID: https://orcid.org/0000-0001-7416-9843 (2005) In vitro and in vivo analysis of macroporous biodegradable poly(D,L-lactide-co-glycolide) scaffolds containing bioactive glass. Journal of Biomedical Materials Research Part A, 75 (4). pp. 778-87. ISSN 1549-3296

Deterding, Alexander, Dungey, Fiona A., Thompson, Katy-Anne and Steverding, Dietmar (2005) Anti-trypanosomal activities of DNA topoisomerase inhibitors. Acta Tropica, 93 (3). pp. 311-316.

Dinh, Q. T., Cryer, A., Dinh, S., Peiser, C., Wu, S., Springer, J., Hamelmann, E., Klapp, B. F., Heppt, W. and Fischer, A. (2005) Transcriptional up-regulation of histamine receptor-1 in epithelial, mucus and inflammatory cells in perennial allergic rhinitis. Clinical & Experimental Allergy, 35 (11). pp. 1443-1448. ISSN 0954-7894

Dong, Changjiang, Flecks, Silvana, Unversucht, Susanne, Haupt, Caroline, van Pée, Karl-Heinz and Naismith, James H (2005) Tryptophan 7-halogenase (PrnA) structure suggests a mechanism for regioselective chlorination. Science, 309 (5744). pp. 2216-9. ISSN 0036-8075

E

Egan, Charlotte E., Dalton, Jane E., Andrew, Elizabeth M., Smith, Judith E., Gubbels, Marc-Jan, Striepen, Boris and Carding, Simon R. (2005) A requirement for the Vgamma1+ subset of peripheral gammadelta T cells in the control of the systemic growth of Toxoplasma gondii and infection-induced pathology. Journal of Immunology, 175 (12). pp. 8191-8199. ISSN 0022-1767

F

Farrar, M.D., Whitehead, T.R., Lan, J., Dilger, P., Thorpe, R., Holland, K.T. and Carding, S.R. (2005) Engineering of the gut commensal bacterium Bacteroides ovatus to produce and secrete biologically active murine interleukin-2 in response to xylan. Journal of Applied Microbiology, 98 (5). pp. 1191-1197. ISSN 1364-5072

Forbes, A ORCID: https://orcid.org/0000-0001-7416-9843, Al-Damluji, A, Ashworth, S, Bramble, M, Herbert, K, Ho, J, Kang, J-Y, Przemioslo, R and Shetty, A (2005) Multicentre randomized-controlled clinical trial of Ipocol, a new enteric-coated form of mesalazine, in comparison with Asacol in the treatment of ulcerative colitis. Alimentary Pharmacology and Therapeutics, 21 (9). pp. 1099-1104. ISSN 0269-2813

Forbes, Alastair ORCID: https://orcid.org/0000-0001-7416-9843, Jackson, Sue, Walter, Clare, Quraishi, Shafi, Jacyna, Meron and Pitcher, Max (2005) Acupuncture for irritable bowel syndrome: A blinded placebo-controlled trial. World Journal of Gastroenterology, 11 (26). pp. 4040-4044. ISSN 1007-9327

Forester, Nerys D., Cruickshank, Sheena M., Scott, D. Julian A. and Carding, Simon R (2005) Functional characterization of T cells in abdominal aortic aneurysms. Immunology, 115 (2). pp. 262-270. ISSN 0019-2805

G

Gardiner, Natalie J., Fernyhough, Paul, Tomlinson, David R., Mayer, Ulrike ORCID: https://orcid.org/0000-0003-2328-0052, von der Mark, Helga and Streuli, Charles H. (2005) alpha7 integrin mediates axon regeneration of distinct populations of adult sensory neurons. Molecular and Cellular Neuroscience, 28 (2). pp. 229-240.

Ginger, Michael L., Ngazoa, E. Solange, Pereira, Claudio A., Pullen, Timothy J., Kabiri, Mostafa, Becker, Katja, Gull, Keith and Steverding, Dietmar (2005) Intracellular positioning of isoforms explains an unusually large adenylate kinase gene family in the parasite Trypanosoma brucei. Journal of Biological Chemistry, 280 (12). pp. 11781-11789. ISSN 1083-351X

H

Halfter, Willi, Willem, Michael and Mayer, Ulrike ORCID: https://orcid.org/0000-0003-2328-0052 (2005) Basement membrane-dependent survival of retinal ganglion cells. Investigative Ophthalmology and Visual Science, 46. pp. 1000-1009. ISSN 1552-5783

J

Jansen, Guus H E, Arts, Ilja C W, Nielen, Michel W F, Müller, Michael ORCID: https://orcid.org/0000-0002-5930-9905, Hollman, Peter C H and Keijer, Jaap (2005) Uptake and metabolism of enterolactone and enterodiol by human colon epithelial cells. Archives of Biochemistry and Biophysics, 435 (1). pp. 74-82. ISSN 0003-9861

Jewell, Derek P., Satsangi, Jack, Lobo, Alan, Probert, Christopher, Forbes, Alastair ORCID: https://orcid.org/0000-0001-7416-9843, Ghosh, Subrata, Shaffer, Jon, Frenz, Markus, Drummond, Hazel, Troy, Gill, Turner, Sue, Younge, Lisa, Evans, Lyn, Moosa, Mark, Rodgers-Gray, Barry and Buchan, Scot (2005) Infliximab use in Crohn's disease: Impact on health care resources in the UK. European Journal of Gastroenterology & Hepatology, 17 (10). pp. 1047-52. ISSN 0954-691X

Jouvenet, Nolween and Wileman, Thomas (2005) African swine fever virus infection disrupts centrosome assembly and function. Journal of General Virology, 86 (3). pp. 589-594. ISSN 1465-2099

K

Kaput, Jim, Ordovas, Jose M, Ferguson, Lynnette, van Ommen, Ben, Rodriguez, Raymond L, Allen, Lindsay, Ames, Bruce N, Dawson, Kevin, German, Bruce, Krauss, Ronald, Malyj, Wasyl, Archer, Michael C, Barnes, Stephen, Bartholomew, Amelia, Birk, Ruth, van Bladeren, Peter, Bradford, Kent J, Brown, Kenneth H, Caetano, Rosane, Castle, David, Chadwick, Ruth, Clarke, Stephen, Clément, Karine, Cooney, Craig A, Corella, Dolores, Manica da Cruz, Ivana Beatrice, Daniel, Hannelore, Duster, Troy, Ebbesson, Sven O E, Elliott, Ruan, Fairweather-Tait, Susan ORCID: https://orcid.org/0000-0002-1413-5569, Felton, Jim, Fenech, Michael, Finley, John W, Fogg-Johnson, Nancy, Gill-Garrison, Rosalynn, Gibney, Michael J, Gillies, Peter J, Gustafsson, Jan-Ake, Hartman, John L, He, Lin, Hwang, Jae-Kwan, Jais, Jean-Philippe, Jang, Yangsoo, Joost, Hans, Junien, Claudine, Kanter, Mitchell, Kibbe, Warren A, Koletzko, Berthold, Korf, Bruce R, Kornman, Kenneth, Krempin, David W, Langin, Dominique, Lauren, Denis R, Ho Lee, Jong, Leveille, Gilbert A, Lin, Su-Ju, Mathers, John, Mayne, Michael, McNabb, Warren, Milner, John A, Morgan, Peter, Muller, Michael ORCID: https://orcid.org/0000-0002-5930-9905, Nikolsky, Yuri, van der Ouderaa, Frans, Park, Taesun, Pensel, Norma, Perez-Jimenez, Francisco, Poutanen, Kaisa, Roberts, Matthew, Saris, Wim H M, Schuster, Gertrud, Shelling, Andrew N, Simopoulos, Artemis P, Southon, Sue, Tai, E Shyong, Towne, Bradford, Trayhurn, Paul, Uauy, Ricardo, Visek, Willard J, Warden, Craig, Weiss, Rick, Wiencke, John, Winkler, Jack, Wolff, George L, Zhao-Wilson, Xi and Zucker, Jean-Daniel (2005) The case for strategic international alliances to harness nutritional genomics for public and personal health. British Journal of Nutrition, 94 (5). pp. 623-632. ISSN 0007-1145

Keshaw, Hussila, Forbes, Alastair ORCID: https://orcid.org/0000-0001-7416-9843 and Day, Richard M (2005) Release of angiogenic growth factors from cells encapsulated in alginate beads with bioactive glass. Biomaterials, 26 (19). pp. 4171-9. ISSN 0142-9612

Kitchen, Paul A., Goodlad, Robert A., FitzGerald, Anthony J., Mandir, Nikki, Ghatei, Mohammed A., Bloom, Stephen R., Berlanga-Acosta, Jorge, Playford, Raymond J., Forbes, Alastair ORCID: https://orcid.org/0000-0001-7416-9843 and Walters, Julian R. F. (2005) Intestinal growth in parenterally-fed rats induced by the combined effects of glucagon-like peptide 2 and epidermal growth factor. Journal of Parenteral and Enteral Nutrition, 29 (4). pp. 248-254. ISSN 0148-6071

Klein, Christian, Wüstefeld, Torsten, Assmus, Ulrike, Roskams, Tania, Rose-John, Stefan, Müller, Michael ORCID: https://orcid.org/0000-0002-5930-9905, Manns, Michael P, Ernst, Mattias and Trautwein, Christian (2005) The IL-6-gp130-STAT3 pathway in hepatocytes triggers liver protection in T cell-mediated liver injury. Journal of Clinical Investigation, 115 (4). pp. 860-9. ISSN 0021-9738

Knox, Caroline, Moffat, Katy, Ali, Shireen, Ryan, Martin and Wileman, Thomas (2005) Foot-and-mouth disease virus replication sites form next to the nucleus and close to the Golgi apparatus, but exclude marker proteins associated with host membrane compartments. Journal of General Virology, 86 (3). pp. 687-696. ISSN 1465-2099

L

La Rocca, S. Anna, Herbert, Rebecca J., Crooke, Helen, Drew, Trevor W., Wileman, Thomas E. and Powell, Penny P. ORCID: https://orcid.org/0000-0002-5347-0490 (2005) Loss of interferon regulatory factor 3 in cells infected with classical swine fever virus involves the N-terminal protease, Npro. Journal of Virology, 79 (11). pp. 7239-7247.

Lopez, M.A., Mayer, U. ORCID: https://orcid.org/0000-0003-2328-0052, Hwang, W., Taylor, T., Hashmi, M.A., Jannapureddy, S.R. and Boriek, A.M. (2005) Force transmission, compliance, and viscoelasticity are altered in the alpha7-integrin-null mouse diaphragm. American Journal of Physiology - Cell Physiology, 288 (2). C282-C289. ISSN 0363-6143

M

Marches, Olivier, Wiles, Siouxsie, Dziva, Francis, La Ragione, Roberto M., Schuller, Stephanie ORCID: https://orcid.org/0000-0003-3260-9112, Best, Angus, Phillips, Alan D., Hartland, Elizabeth L., Woodward, Martin J., Stevens, Mark P. and Frankel, Gad (2005) Characterization of two non-locus of enterocyte effacement-encoded type III-translocated effectors, NleC and NleD, in attaching and effacing pathogens. Infection and Immunity, 73 (12). pp. 8411-8417. ISSN 0019-9567

Moffat, Katy, Howell, Gareth, Knox, Caroline, Belsham, Graham J., Monaghan, Paul, Ryan, Martin D. and Wileman, Thomas (2005) Effects of foot-and-mouth disease virus nonstructural proteins on the structure and function of the early secretory pathway: 2BC but not 3A blocks endoplasmic reticulum-to-Golgi transport. Journal of Virology, 79 (7). pp. 4382-4395.

Myhill, D. J., Abubakar, I. I., Lake, I. R. ORCID: https://orcid.org/0000-0003-4407-5357, Harvey, I. M., Hunter, P. R. ORCID: https://orcid.org/0000-0002-5608-6144 and Hart, A. R. (2005) Drinking Water & Dairy Products in the Etiology of Crohn's Disease - A Possible Role for Mycobacterium avium paratuberculosis. In: World Congress of Gastroenterology, 2005-01-01.

O

Ogunwobi, O. O. and Beales, I. L. P. (2005) Adiponectin stimulates proliferation and interleukin-8 secretion by colonic epithelial cells. Gut, 54 (2). ISSN 1468-3288

Ogunwobi, O. O. and Beales, I. L. P. (2005) Glycine-extended gastin stimulates proliferation of oesophageal adenocarcinoma cells via cyclo-oxygenase-2 dependent pathways. In: Gut, 2005-01-01.

Ogunwobi, O. O. and Beales, I. L. P. (2005) Glycine-extended gastrin stimulates proliferation and inhibits apoptosis in colon cancer cells via multiple pathways. Gut, 54 (2). p. 216. ISSN 1468-3288

Ogunwobi, O. O. and Beales, I. L. P. (2005) Leptin enhances the cell proliferative and anti-apoptotic actions of acid in Barrett's adencocarcinoma. Gut, 54 (7). p. 70. ISSN 1468-3288

Ogunwobi, O. O. and Beales, I. L. P. (2005) Statins inhibit proliferation oesophageal adenocarcinoma cells. Gut, 54 (7). p. 35. ISSN 1468-3288

P

Prescott, N J, Fisher, S A, Onnie, C, Pattni, R, Steer, S, Sanderson, J, Forbes, A ORCID: https://orcid.org/0000-0001-7416-9843, Lewis, C M and Mathew, C G (2005) A general autoimmunity gene (PTPN22) is not associated with inflammatory bowel disease in a British population. Tissue Antigens, 66 (4). pp. 318-320. ISSN 0001-2815

S

Shen, Lin-nan, Liu, Huanting, Dong, Changjiang, Xirodimas, Dimitris, Naismith, James H and Hay, Ronald T (2005) Structural basis of NEDD8 ubiquitin discrimination by the deNEDDylating enzyme NEDP1. The EMBO Journal, 24 (7). pp. 1341-51. ISSN 0261-4189

Springer, Jochen, Groneberg, David A., Pregla, Reinhard and Fischer, Axel (2005) Inflammatory cells as source of tachykinin-induced mucus secretion in chronic bronchitis. Regulatory Peptides, 124 (1-3). pp. 195-201. ISSN 1873-1686

Springer, Jochen, Pleimes, Dirk, Scholz, Frank R. and Fischer, Axel (2005) Substance P mediates AP-1 induction in A549 cells via reactive oxygen species. Regulatory Peptides, 124 (1-3). pp. 99-103. ISSN 1873-1686

Springer, Jochen, Ruth, Peter, Beuerlein, Knut, Palus, Sandra, Schipp, Rudolf and Westermann, Bettina (2005) Distribution and function of biogenic amines in the heart of Nautilus pompilius L. (Cephalopoda, Tetrabranchiata). Journal of Molecular Histology, 36 (5). pp. 345-353. ISSN 1567-2379

Stefanovic, Sandra, Windsor, Miriam, Nagata, Koh-ici, Inagaki, Masaki and Wileman, Thomas (2005) Vimentin rearrangement during African swine fever virus infection involves retrograde transport along microtubules and phosphorylation of vimentin by calcium calmodulin kinase II. Journal of Virology, 79 (18). pp. 11766-11775.

Steverding, Dietmar, Morgan, Edward, Tkaczynski, Patrick, Walder, Foster and Tinsley, Richard (2005) Effect of Australian tea tree oil on Gyrodactylus spp. infection of the three-spined stickleback Gasterosteus aculeatus. Diseases of Aquatic Organisms, 66 (1). pp. 29-32. ISSN 0177-5103

Steverding, Dietmar, Spackman, Robert W, Royle, Howard J and Glenn, Robert J (2005) Trypanocidal activities of trileucine methyl vinyl sulfone proteasome inhibitors. Parasitology Research, 95 (1). pp. 73-76. ISSN 0932-0113

Steverding, Dietmar and Tyler, Kevin M. ORCID: https://orcid.org/0000-0002-0647-8158 (2005) Novel antitrypanosomal agents. Expert Opinion on Investigational Drugs, 14 (8). pp. 939-955. ISSN 1354-3784

Stirling, Catrina M., Charleston, Bryan, Takamatsu, Haru, Claypool, Steven, Lencer, Wayne, Blumberg, Richard S. and Wileman, Thomas E. (2005) Characterization of the porcine neonatal Fc receptor--potential use for trans-epithelial protein delivery. Immunology, 114 (4). pp. 542-553. ISSN 1365-2567

Strassburg, Sabine, Springer, Jochen and Anker, Stefan D. (2005) Muscle wasting in cardiac cachexia. International Journal of Biochemistry & Cell Biology, 37 (10). pp. 1938-1947. ISSN 1878-5875

T

Tyler, Kevin M. ORCID: https://orcid.org/0000-0002-0647-8158, Luxton, George W. G., Applewhite, Derek A., Murphy, Sean C. and Engman, David M. (2005) Responsive microtubule dynamics promote cell invasion by Trypanosoma cruzi. Cellular Microbiology, 7 (11). pp. 1579-1591. ISSN 1462-5822

V

van Heel, D A, Ghosh, S, Hunt, K A, Mathew, C G, Forbes, A ORCID: https://orcid.org/0000-0001-7416-9843, Jewell, D P and Playford, R J (2005) Synergy between TLR9 and NOD2 innate immune responses is lost in genetic Crohn's disease. Gut, 54 (11). pp. 1553-7. ISSN 0017-5749

van Heel, David A, Ghosh, Subrata, Butler, Matt, Hunt, Karen A, Lundberg, Anna M C, Ahmad, Tariq, McGovern, Dermot P B, Onnie, Clive, Negoro, Kenichi, Goldthorpe, Sue, Foxwell, Brian M J, Mathew, Christopher G, Forbes, Alastair ORCID: https://orcid.org/0000-0001-7416-9843, Jewell, Derek P and Playford, Raymond J (2005) Muramyl dipeptide and toll-like receptor sensitivity in NOD2-associated Crohn's disease. Lancet, 365 (9473). pp. 1794-1796. ISSN 0140-6736

W

Watson, Alastair J M ORCID: https://orcid.org/0000-0003-3326-0426, Chu, Shaoyou, Sieck, Leah, Gerasimenko, Oleg, Bullen, Tim, Campbell, Fiona, McKenna, Michael, Rose, Tracy and Montrose, Marshall H. (2005) Epithelial barrier function in vivo is sustained despite gaps in epithelial layers. Gastroenterology, 129 (3). pp. 902-912. ISSN 1528-0012

Wilkinson, M., Rodrigues, V. C. ORCID: https://orcid.org/0000-0002-4942-5646, Beales, I. L. P. and Jamieson, C. (2005) Teaching students to use medical notes. In: UNSPECIFIED.

Y

Yang, Huaizhi, Parkhouse, R. Michael E. and Wileman, Thomas (2005) Monoclonal antibodies that identify the CD3 molecules expressed specifically at the surface of porcine gammadelta-T cells. Immunology, 115 (2). pp. 189-196. ISSN 1365-2567

Z

Zandbergen, Fokko, Mandard, Stéphane, Escher, Pascal, Tan, Nguan Soon, Patsouris, David, Jatkoe, Tim, Rojas-Caro, Sandra, Madore, Steve, Wahli, Walter, Tafuri, Sherrie, Müller, Michael ORCID: https://orcid.org/0000-0002-5930-9905 and Kersten, Sander (2005) The G0/G1 switch gene 2 is a novel PPAR target gene. Biochemical Journal, 392 (Pt 2). pp. 313-24. ISSN 0264-6021