The case for strategic international alliances to harness nutritional genomics for public and personal health

Kaput, Jim, Ordovas, Jose M, Ferguson, Lynnette, van Ommen, Ben, Rodriguez, Raymond L, Allen, Lindsay, Ames, Bruce N, Dawson, Kevin, German, Bruce, Krauss, Ronald, Malyj, Wasyl, Archer, Michael C, Barnes, Stephen, Bartholomew, Amelia, Birk, Ruth, van Bladeren, Peter, Bradford, Kent J, Brown, Kenneth H, Caetano, Rosane, Castle, David, Chadwick, Ruth, Clarke, Stephen, Clément, Karine, Cooney, Craig A, Corella, Dolores, Manica da Cruz, Ivana Beatrice, Daniel, Hannelore, Duster, Troy, Ebbesson, Sven O E, Elliott, Ruan, Fairweather-Tait, Susan ORCID: https://orcid.org/0000-0002-1413-5569, Felton, Jim, Fenech, Michael, Finley, John W, Fogg-Johnson, Nancy, Gill-Garrison, Rosalynn, Gibney, Michael J, Gillies, Peter J, Gustafsson, Jan-Ake, Hartman, John L, He, Lin, Hwang, Jae-Kwan, Jais, Jean-Philippe, Jang, Yangsoo, Joost, Hans, Junien, Claudine, Kanter, Mitchell, Kibbe, Warren A, Koletzko, Berthold, Korf, Bruce R, Kornman, Kenneth, Krempin, David W, Langin, Dominique, Lauren, Denis R, Ho Lee, Jong, Leveille, Gilbert A, Lin, Su-Ju, Mathers, John, Mayne, Michael, McNabb, Warren, Milner, John A, Morgan, Peter, Muller, Michael ORCID: https://orcid.org/0000-0002-5930-9905, Nikolsky, Yuri, van der Ouderaa, Frans, Park, Taesun, Pensel, Norma, Perez-Jimenez, Francisco, Poutanen, Kaisa, Roberts, Matthew, Saris, Wim H M, Schuster, Gertrud, Shelling, Andrew N, Simopoulos, Artemis P, Southon, Sue, Tai, E Shyong, Towne, Bradford, Trayhurn, Paul, Uauy, Ricardo, Visek, Willard J, Warden, Craig, Weiss, Rick, Wiencke, John, Winkler, Jack, Wolff, George L, Zhao-Wilson, Xi and Zucker, Jean-Daniel (2005) The case for strategic international alliances to harness nutritional genomics for public and personal health. British Journal of Nutrition, 94 (5). pp. 623-632. ISSN 0007-1145

Full text not available from this repository. (Request a copy)

Abstract

Nutrigenomics is the study of how constituents of the diet interact with genes, and their products, to alter phenotype and, conversely, how genes and their products metabolise these constituents into nutrients, antinutrients, and bioactive compounds. Results from molecular and genetic epidemiological studies indicate that dietary unbalance can alter gene-nutrient interactions in ways that increase the risk of developing chronic disease. The interplay of human genetic variation and environmental factors will make identifying causative genes and nutrients a formidable, but not intractable, challenge. We provide specific recommendations for how to best meet this challenge and discuss the need for new methodologies and the use of comprehensive analyses of nutrient-genotype interactions involving large and diverse populations. The objective of the present paper is to stimulate discourse and collaboration among nutrigenomic researchers and stakeholders, a process that will lead to an increase in global health and wellness by reducing health disparities in developed and developing countries.

Item Type:	Article
Uncontrolled Keywords:	animals,disease models, animal,eating,environment,genetic variation,genome, human,genomics,humans,international cooperation,nutritional physiological phenomena,phenotype,research,sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School Faculty of Social Sciences > School of Education and Lifelong Learning Faculty of Science > School of Biological Sciences
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Nutrition and Preventive Medicine Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology Faculty of Medicine and Health Sciences > Research Groups > Musculoskeletal Medicine
Depositing User:	Rhiannon Harvey
Date Deposited:	04 Jul 2011 15:56
Last Modified:	01 Mar 2023 16:30
URI:	https://ueaeprints.uea.ac.uk/id/eprint/33318
DOI:	10.1079/BJN20051585

Actions (login required)

View Item