Items where Author is "Hamilton, Christopher"

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Article

Chi, Bui Khanh, Huyen, Nguyen Thi Thu, Loi, Vu Van, Gruhlke, Martin, Schaffer, Marc, Mäder, Ulrike, Maaß, Sandra, Becher, Dorte, Bernhardt, Jorg, Arbach, Miriam, Hamilton, Chris J., Slusarenko, Alan J. and Antelmann, Haike (2019) The Disulfide Stress Response and Protein S-thioallylation Caused by Allicin and Diallyl Polysulfanes in Bacillus subtilis as Revealed by Transcriptomics and Proteomics. Antioxidants, 8 (12). ISSN 2076-3921

Linzner, Nico, Loi, Vu Van, Fritsch, Verena Nadin, Tung, Quach Ngoc, Stenzel, Saskia, Wirtz, Markus, Hell, Rüdiger, Hamilton, Chris J., Tedin, Karsten, Fulde, Marcus and Antelmann, Haike (2019) Staphylococcus aureus Uses the Bacilliredoxin (BrxAB)/Bacillithiol Disulfide Reductase (YpdA) Redox Pathway to Defend Against Oxidative Stress Under Infections. Frontiers in Microbiology, 10. ISSN 1664-302X

Arbach, Miriam, Santana, Taris M., Moxham, Hazel, Tinson, Ryan, Anwar, Awais, Groom, Murree and Hamilton, Christopher (2019) Antimicrobial garlic-derived diallyl polysulfanes:Interactions with biological thiols in Bacillus subtilis. Biochimica et Biophysica Acta - General Subjects, 1863 (6). pp. 1050-1058. ISSN 0304-4165

Kay, Kristine L., Hamilton, Chris J. and Le Brun, Nick E. (2019) Mass spectrometric studies of Cu(I)-binding to the N-terminal domains of B. subtilis CopA and influence of bacillithiol. Journal of Inorganic Biochemistry, 190. pp. 24-30. ISSN 0162-0134

Hiras, Jennifer, Sharma, Sunil V., Raman, Vidhyavathi, Tinson, Ryan A. J., Arbach, Miriam, Rodrigues, Dominic F., Norambuena, Javiera, Hamilton, Chris J. and Hanson, Thomas E. (2018) Physiological Studies of Chlorobiaceae Suggest that Bacillithiol Derivatives Are the Most Widespread Thiols in Bacteria. mBIO, 9 (6). ISSN 2150-7511

Anwar, Awais, Gould, Emma, Tinson, Ryan, Iqbal, Javaid and Hamilton, Chris (2018) Redox Modulation at Work: Natural Phytoprotective Polysulfanes From Alliums Based on Redox-Active Sulfur. Current Pharmacology Reports, 4 (5). 397–407. ISSN 2198-641X

Crack, Jason C., Hamilton, Chris J. and Le Brun, Nick E. (2018) Mass spectrometric detection of iron nitrosyls, sulfide oxidation and mycothiolation during nitrosylation of the NO sensor [4Fe-4S] NsrR. Chemical Communications, 54 (47). pp. 5992-5995. ISSN 1359-7345

Imber, Marcel, Loi, Vu Van, Reznikov, Sylvia, Fritsch, Verena Nadin, Pietrzyk-Brzezinska, Agnieszka J., Prehn, Janek, Hamilton, Chris, Wahl, Markus C., Bronowska, Agnieszka K. and Antelmann, Haike (2018) The aldehyde dehydrogenase AldA contributes to the hypochlorite defense and is redox-controlled by protein S-bacillithiolation in Staphylococcus aureus. Redox Biology, 15. 557–568. ISSN 2213-2317

Imber, Marcel, Huyen, Nguyen Thi Thu, Pietrzyk-Brzezinska, Agnieszka J., Loi, Vu Van, Hillion, Melanie, Bernhardt, Jörg, Thärichen, Lena, Kolšek, Katra, Saleh, Malek, Hamilton, Chris J., Adrian, Lorenz, Gräter, Frauke, Wahl, Markus C. and Antelmann, Haike (2018) Protein S-Bacillithiolation Functions in Thiol Protection and Redox Regulation of the Glyceraldehyde-3-Phosphate Dehydrogenase Gap in Staphylococcus aureus Under Hypochlorite Stress. Antioxidants & Redox Signaling, 28 (6). pp. 410-430. ISSN 1523-0864

Bulman Page, Philip C., Goodyear, Ross L., Horton, Alexandra E., Chan, Yohan, Karim, Rehana, O'Connell, Maria A., Hamilton, Christopher, Slawin, Alexandra M. Z., Buckley, Benjamin R. and Allin, Steven M. (2017) Formal Total Synthesis of (+)-C9-Deoxyomuralide from l-Leucine Using a Double Sacrificial Chirality Transfer Approach. The Journal of Organic Chemistry, 82 (23). 12209–12223. ISSN 0022-3263

Oosthuizen, Carel, Arbach, Miriam, Meyer, Debra, Hamilton, Chris and Lall, Namrita (2017) Diallyl Polysulfides from Allium sativum as Immunomodulators, Hepatoprotectors, and Antimycobacterial Agents. Journal of Medicinal Food, 20 (7). pp. 685-690. ISSN 1096-620X

Loi, Vu Van, Harms, Manuela, Müller, Marret, Huyen, Nguyen Thi Thu, Hamilton, Christopher J., Hochgräfe, Falko, Pane-Farre, Jan and Antelmann, Haike (2017) Real-time imaging of the bacillithiol redox potential in the human pathogen Staphylococcus aureus using a genetically encoded bacilliredoxin-fused redox biosensor. Antioxidants & Redox Signaling, 26 (15). pp. 835-848. ISSN 1523-0864

Anwar, Awais, Gould, Emma, Tinson, Ryan, Groom, Murree and Hamilton, Chris J. (2016) Think Yellow and Keep Green—Role of Sulfanes from Garlic in Agriculture. Antioxidants, 6 (1). ISSN 2076-3921

Lall, Namrita, Kumar, Vivek, Meyer, Debra, Gasa, Nomasomi, Hamilton, Chris, Matsabisa, Motlalepula and Oosthuizen, Carel (2016) In vitro and In vivo antimycobacterial, hepatoprotective and immunomodulatory activity of Euclea natalensis and its mode of action. Journal of Ethnopharmacology, 194. 740–748. ISSN 0378-8741

Sharma, Sunil V, Van Laer, Koen, Messens, Joris and Hamilton, Chris James (2016) Thiol redox and pKa properties of mycothiol, the predomiant low molecular weight thiol cofactor in the Actinomycetes. ChemBioChem, 17 (18). 1689–1692. ISSN 1439-4227

Kay, Kristine L., Hamilton, Chris J. and Le Brun, Nick E. (2016) Mass spectrometry of B. subtilis CopZ: Cu(I)-binding and interactions with bacillithiol. Metallomics, 8 (7). pp. 709-719. ISSN 1756-591X

Wang, Wei, He, Yan, Yu, Guodong, Li, Baolong, Sexton, Darren W., Wileman, Thomas, Roberts, Alexandra A., Hamilton, Chris J., Liu, Ruoxi, Chao, Yimin, Shan, Yujuan and Bao, Yongping (2015) Sulforaphane protects the liver against CdSe quantum dot-induced cytotoxicity. PLoS One, 10 (9). ISSN 1932-6203

Crack, Jason, Munnoch, John Tyson, Dodd, Erin, Knowles, Felicity, Al-Bassam, Mahmoud, Kamali, Saeed, Holland, Ashley, Cramer, Stephen, Hamilton, Christopher, Johnson, Michael, Thomson, Andrew, Hutchings, Matthew and Le Brun, Nick (2015) NsrR from Streptomyces coelicolor is a nitric oxide-sensing [4Fe-4S] cluster protein with a specialized regulatory function. The Journal of Biological Chemistry, 290. pp. 12689-12704. ISSN 1083-351X

O'neill, Ellis C., Trick, Martin, Hill, Lionel, Rejzek, Martin, Dusi, Renata G., Hamilton, Chris J., Zimba, Paul V., Henrissat, Bernard and Field, Robert A. (2015) The transcriptome of Euglena gracilis reveals unexpected metabolic capabilities for carbohydrate and natural product biochemistry. Molecular BioSystems, 11 (10). pp. 2808-2820. ISSN 1742-206X

Gaballa, Ahmed, Chi, Bui Khanh, Roberts, Alexandra A., Becher, Dörte, Hamilton, Christopher, Antelmann, Haike and Helmann, John D. (2014) Redox Regulation in Bacillus subtilis: The Bacilliredoxins BrxA(YphP) and BrxB(YqiW) Function in De-bacillithiolation of S-Bacillithiolated OhrR and MetE. Antioxidants & Redox Signaling, 21 (3). pp. 357-367. ISSN 1523-0864

Chandrangsu, Pete, Dusi, Renata, Hamilton, Chris J. and Helmann, John D. (2014) Methylglyoxal resistance in Bacillus subtilis: contributions of bacillithiol-dependent and independent pathways. Molecular Microbiology, 91 (4). pp. 706-715. ISSN 0950-382X

Luan, Hemi, Meng, Nan, Fu, Jin, Chen, Xiaomin, Xu, Xun, Feng, Qiang, Jiang, Hui, Dai, Jun, Yuan, Xune, Lu, Yanping, Roberts, Alexandra A., Luo, Xiao, Chen, Maoshan, Xu, Shengtao, Li, Jun, Hamilton, Christopher, Fang, Chengxiang and Wang, Jun (2014) Genome-Wide Transcriptome and Antioxidant Analyses on Gamma-Irradiated Phases of Deinococcus radiodurans R1. PLoS One, 9 (1). ISSN 1932-6203

Posada, Ana C., Kolar, Stacey L., Dusi, Renata G., Francois, Patrice, Roberts, Alexandra A., Hamilton, Chris J., Liu, George Y. and Cheung, Ambrose (2014) The Importance of Bacillithiol in the Oxidative Stress Response of Staphylococcus aureus. Infection and Immunity, 82 (1). pp. 316-332. ISSN 0019-9567

Sharma, Sunil V., Arbach, Miriam, Roberts, Alexandra A., Macdonald, Colin J., Groom, Murree and Hamilton, Chris J. (2013) Biophysical Features of Bacillithiol, the Glutathione Surrogate of Bacillus subtilis and other Firmicutes. ChemBioChem, 14 (16). pp. 2160-2168. ISSN 1439-4227

Gaballa, A., Antelmann, H., Hamilton, C. J. and Helmann, J. D. (2013) Regulation of Bacillus subtilis bacillithiol biosynthesis operons by Spx. Microbiology, 159 (Pt_10). pp. 2025-2035. ISSN 1350-0872

Iqbal, Amjid, Chibli, Hicham and Hamilton, Christopher (2013) Stability of aminooxy glycosides to glycosidase catalysed hydrolysis. Carbohydrate Research, 377. pp. 1-3. ISSN 0008-6215

Rajkarnikar, Arishma, Strankman, Andrew, Duran, Shayla, Vargas, Derek, Roberts, Alexandra A., Barretto, Kathryn, Upton, Heather, Hamilton, Christopher J. and Rawat, Mamta (2013) Analysis of mutants disrupted in bacillithiol metabolism in Staphylococcus aureus. Biochemical and Biophysical Research Communications, 436 (2). pp. 128-133. ISSN 0006-291X

Chi, Bui Khanh, Roberts, Alexandra A., Huyen, Tran Thi Thanh, Bäsell, Katrin, Becher, Dörte, Albrecht, Dirk, Hamilton, Chris J. and Antelmann, Haike (2013) S-Bacillithiolation Protects Conserved and Essential Proteins Against Hypochlorite Stress in Firmicutes Bacteria. Antioxidants & Redox Signaling, 18 (11). pp. 1273-1295. ISSN 1523-0864

Pöther, Dierk-Christoph, Gierok, Philipp, Harms, Manuela, Mostertz, Jörg, Hochgräfe, Falko, Antelmann, Haike, Hamilton, Christopher, Borovok, Ilya, Lalk, Michael, Aharonowitz, Yair and Hecker, Michael (2013) Distribution and infection-related functions of bacillithiol in Staphylococcus aureus. International Journal of Medical Microbiology, 303 (3). pp. 114-123. ISSN 1438-4221

Roberts, Alexandra A., Sharma, Sunil V., Strankman, Andrew W., Duran, Shayla R., Rawat, Mamta and Hamilton, Chris J. (2013) Mechanistic studies of FosB: a divalent-metal-dependent bacillithiol-S-transferase that mediates fosfomycin resistance in Staphylococcus aureus. Biochemical Journal, 451 (1). pp. 69-79. ISSN 0264-6021

Fang, Zhong, Roberts, Alexandra A., Weidman, Karissa, Sharma, Sunil C., Claiborne, Al, Hamilton, Christopher and Dos Santos, Patricia C. (2013) Cross functionalities of Bacillus deacetylases involved in bacillithial biosynthesis and bacillitiol-S-conjugate detoxification pathways. Biochemistry Journal, 454 (2). pp. 239-247.

Antelmann, H and Hamilton, CJ (2012) Bacterial mechanisms of reversible protein S-thiolation: structural and mechanistic insights into mycoredoxins. Molecular Microbiology, 86 (4). pp. 759-764. ISSN 1365-2958

Banoz-Sanz, José Ignacio, Sanz-Aparicio, Julia, Whitfield, Hayley, Hamilton, Christopher, Brearley, Charles A. and Gonzalez, Beatriz (2012) Conformational Changes in Inositol 1,3,4,5,6-Pentakisphosphate 2-Kinase upon Substrate Binding:Role of N-terminal lobe and enantiomeric substrate preference. The Journal of Biological Chemistry, 287 (35). pp. 29237-29249. ISSN 1083-351X

Sharma, Sunil V., Jothivasan, Vishnu K., Newton, Gerald L., Upton, Heather, Wakabayashi, Judy I., Kane, Melissa G., Roberts, Alexandra A., Rawat, Mamta, La Clair, James J. and Hamilton, Chris J. (2011) Chemical and chemoenzymatic syntheses of bacillithiol, a unique low molecular weight thiol amongst low G + C Gram positive bacteria. Angewandte Chemie International Edition, 50 (31). pp. 7101-7104. ISSN 1433-7851

Williams, Paula M., Sheldrake, Gary N., Macdonald, Simon J. F. and Hamilton, Chris J. (2011) A chemoenzymatic synthesis of 5a-carba-α-d-mannose-6-phosphate. Carbohydrate Research, 346 (10). pp. 1257-1261. ISSN 1873-426X

Parsonage, Derek, Newton, Gerald L., Holder, Robert C., Wallace, Bret D., Paige, Carleitta, Hamilton, Christopher, Dos Santos, Patricia C., Redinbo, Matthew R., Reid, Sean D. and Claiborne, Al (2010) Characterization of the N-Acetyl-α-d-glucosaminyll-Malate Synthase and Deacetylase Functions for Bacillithiol Biosynthesis in Bacillus anthracis. Biochemistry, 49 (38). pp. 8398-8414.

Stewart, Matthew J. G., Jothivasan, Vishnu Karthik, Rowan, Andrew S., Wagg, Jennifer and Hamilton, Chris J. (2009) Mycothiol disulfide reductase: solid phase synthesis and evaluation of alternative substrate analogues. Organic & Biomolecular Chemistry, 6 (2). pp. 385-390. ISSN 1477-0520

Newton, Gerald L., Rawat, Mamta, La Clair, James J., Jothivasan, Vishnu Karthik, Budiarto, Tanya, Hamilton, Chris J., Claiborne, Al, Helmann, John D. and Fahey, Robert C. (2009) Bacillithiol is an antioxidant thiol produced in Bacilli. Nature Chemical Biology, 5 (9). pp. 625-627. ISSN 1552-4450

Rowan, Andrew S., Nicely, Nathan I., Cochrane, Nicola, Wlassoff, Wjatschesslaw A., Claiborne, Al and Hamilton, Chris J. (2009) Nucleoside triphosphate mimicry: a sugar triazolyl nucleoside as an ATP-competitive inhibitor of B. anthracis pantothenate kinase. Organic & Biomolecular Chemistry, 7 (19). p. 4029. ISSN 1477-0520

Mativandiela, Sannah Patience Nkami, Meyer, Jacob Jacobus Marion, Hussein, Ahmed A., Houghton, Peter J., Hamilton, Chris J. and Lall, Namrita (2008) Activity against Mycobacterium smegmatis and M. tuberculosis by extract of South African medicinal plants. Phytotherapy Research, 22 (6). pp. 841-845. ISSN 0951-418X

Hamilton, Chris J., Finlay, Richard M. J., Stewart, Matthew J. G. and Bonner, Alexandra (2008) Mycothiol disulfide reductase: A continuous assay for slow time-dependent inhibitors. Analytical Biochemistry, 388 (1). pp. 91-96. ISSN 1096-0309

Jothivasan, V. K. and Hamilton, C. J. (2008) Mycothiol: synthesis, biosynthesis and biological functions of the major low molecular weight thiol in actinomycetes. Natural Product Reports, 25 (6). pp. 1091-1117. ISSN 0265-0568

Mahapatra, Anita, Mativandlela, Sannah P. N., Binneman, B., Fourie, P. B., Hamilton, Chris J., Meyer, J. J. M., van der Kooy, F., Houghton, Peter and Lall, Namrita (2007) Activity of 7-methyljuglone derivatives against Mycobacterium tuberculosis and as subversive substrates for mycothiol disulfide reductase. Bioorganic & Medicinal Chemistry, 15 (24). pp. 7638-7646. ISSN 0968-0896

Wlassoff, W. A., Finlay, R. M. J. and Hamilton, C. J. (2007) Practical synthesis of sugar monophosphonucleotides. Synthetic Communications, 37 (17). pp. 2927-2934. ISSN 0039-7911

Hamilton, C. J., Saravanamuthu, A., Poupat, C., Fairlamb, A. H. and Eggleston, I. M. (2006) Time-dependent inhibitors of trypanothione reductase: Analogues of the spermidine alkaloid lunarine and related natural products. Bioorganic & Medicinal Chemistry, 14 (7). pp. 2266-2278. ISSN 0968-0896

Rowan, A. S. and Hamilton, C. J. (2006) Recent developments in preparative enzymatic syntheses of carbohydrates. Natural Product Reports, 23 (3). pp. 412-443. ISSN 0265-0568

Hamilton, C. J. (2004) Enzymes in preparative mono- and oligo-saccharide synthesis. Natural Product Reports, 21 (3). pp. 365-385. ISSN 0265-0568

Woods, Katherine, Hamilton, Chris J. and Field, Robert A. (2004) Enzymatic liberation of lycotetraose from the Solanum glycoalkaloid alpha-tomatine. Carbohydrate Research, 339 (13). pp. 2325-2328. ISSN 0008-6215

Hamilton, C. J., Saravanamuthu, A., Eggleston, I. M. and Fairlamb, A. H. (2003) Ellman's-reagent-mediated regeneration of trypanothione in situ: substrate economical microplate and time-dependent inhibition assays for trypanothione reductase. Biochemical Journal, 369. pp. 529-537. ISSN 0264-6021

Hamilton, C. J., Saravanamuthu, A., Fairlamb, A. H. and Eggleston, I. M. (2003) Benzofuranyl 3,5-bis-polyamine derivatives as time-dependent inhibitors of trypanothione reductase. Bioorganic & Medicinal Chemistry, 11 (17). pp. 3683-3693. ISSN 0968-0896

Sarkar, M., Hamilton, C. J. and Fairlamb, A. H. (2003) Properties of phosphoenolpyruvate mutase, the first enzyme in the aminoethylphosphonate biosynthetic pathway in Trypanosoma cruzi. Journal of Biological Chemistry, 278 (25). pp. 22703-22708. ISSN 0021-9258

Hamilton, Chris J., Fairlamb, Alan H. and Eggleston, Ian M. (2002) Regiocontrolled synthesis of the macrocyclic polyamine alkaloid (+/-)-lunarine, a time-dependent inhibitor of trypanothione reductase. Journal of the Chemical Society, Perkin Transactions 1, 1 (8). pp. 1115-1123. ISSN 1472-7781

Shipitsin, Alexander V., Victorova, Lyubov S., Shirokova, Elena A., Dyatkina, Natalya B., Goryunova, Lyudmila E., Beabealashvilli, Robert Sh., Hamilton, Chris J., Roberts, Stanley M. and Krayevsky, Alexander (1999) New modified nucleoside 5′-triphosphates: synthesis, properties towards DNA polymerases, stability in blood serum and antiviral activity. Journal of the Chemical Society, Perkin Transactions 1 (8). pp. 1039-1050. ISSN 1472-7781

Hamilton, Chris J. and Roberts, Stanley M. (1999) Synthesis of fluorinated phosphonoacetate derivatives of carbocyclic nucleoside monophosphonates and activity as inhibitors of HIV reverse transcriptase. Journal of the Chemical Society, Perkin Transactions 1 (8). pp. 1051-1056. ISSN 1472-7781

Hamilton, Chris J., Roberts, Stanley M. and Shipitsin, Alexander (1998) Synthesis of a potent inhibitor of HIV reverse transcriptase. Chemical Communications (10). pp. 1087-1088. ISSN 1359-7345

This list was generated on Sun Mar 29 20:10:11 2020 BST.