Items where Author is "Savva, George"

Article

Corrado, Marina, Koev, Todor T. ORCID: https://orcid.org/0000-0002-8218-9753, Savva, George M., Khimyak, Yaroslav Z. ORCID: https://orcid.org/0000-0003-0424-4128 and Hazard, Brittany A. (2024) Starch characteristics and baking quality of chilled ready-to-eat sandwich bread made with starch branching enzyme II mutant wheat flour. Food Hydrocolloids, 147 (Part B). ISSN 0268-005X

Coletto, Erika, Savva, George M., Latousakis, Dimitrios, Pontifex, Matthew ORCID: https://orcid.org/0000-0003-2174-2313, Crost, Emmanuelle H., Vaux, Laura, Telatin, Andrea, Bergstrom, Kirk, Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756 and Juge, Nathalie (2023) Role of mucin glycosylation in the gut microbiota-brain axis of core 3 O-glycan deficient mice. Scientific Reports, 13. ISSN 2045-2322

Phillips, Sarah, Watt, Rachel, Atkinson, Thomas, Rajan, Shelina, Hayhoe, Antonietta, Savva, George M., Hornberger, Michael ORCID: https://orcid.org/0000-0002-2214-3788, Burton, Ben J. L., Saada, Janak, Cambell-Kelly, Melissa, Rushbrook, Simon and Carding, Simon R. (2022) A protocol paper for the MOTION Study—A longitudinal study in a cohort aged 60 years and older to obtain mechanistic knowledge of the role of the gut microbiome during normal healthy ageing in order to develop strategies that will improve lifelong health and wellbeing. PLoS One, 17 (11). ISSN 1932-6203

Coletto, Erika, Latousakis, Dimitrios, Pontifex, Matthew G. ORCID: https://orcid.org/0000-0003-2174-2313, Crost, Emmanuelle H., Vaux, Laura, Perez Santamarina, Estella, Goldson, Andrew, Brion, Arlaine, Hajihosseini, Mohammad K., Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756, Savva, George M. and Juge, Nathalie (2022) The role of the mucin-glycan foraging Ruminococcus gnavus in the communication between the gut and the brain. Gut Microbes, 14 (1). ISSN 1949-0976

Parker, Aimée, Romano, Stefano, Ansorge, Rebecca, Aboelnour, Asmaa, Le Gall, Gwenaelle ORCID: https://orcid.org/0000-0002-1379-2196, Savva, George M., Pontifex, Matthew G. ORCID: https://orcid.org/0000-0003-2174-2313, Telatin, Andrea, Baker, David, Jones, Emily, Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756, Rudder, Steven, Blackshaw, L. Ashley, Jeffery, Glen and Carding, Simon R. (2022) Fecal microbiota transfer between young and aged mice reverses hallmarks of the aging gut, eye, and brain. Microbiome, 10. ISSN 2049-2618

Aggarwal, Dinesh, Page, Andrew J., Schaefer, Ulf, Savva, George M., Myers, Richard, Volz, Erik, Ellaby, Nicholas, Platt, Steven, Groves, Natalie, Gallagher, Eileen, Tumelty, Niamh M., Le Viet, Thanh, Hughes, Gareth J., Chen, Cong, Turner, Charlie, Logan, Sophie, Harrison, Abbie, Peacock, Sharon J., Chand, Meera and Harrison, Ewan M. and COVID-19 Genomics UK (COG-UK) Consortium (2022) Genomic assessment of quarantine measures to prevent SARS-CoV-2 importation and transmission. Nature Communications, 13. ISSN 2041-1723

Hsieh, Shen-Yuan, Tariq, Mohammad A., Telatin, Andrea, Ansorge, Rebecca, Adriaenssens, Evelien M., Savva, George M., Booth, Catherine, Wileman, Tom, Hoyles, Lesley and Carding, Simon R. (2021) Comparison of PCR versus PCR-Free DNA library preparation for characterising the human faecal virome. Viruses, 13 (10). ISSN 1999-4915

Jones, Emily, Stentz, Régis, Telatin, Andrea, Savva, George M., Booth, Catherine, Baker, David, Rudder, Steven, Knight, Stella C., Noble, Alistair and Carding, Simon R. (2021) The origin of plasma-derived bacterial extracellular vesicles in healthy individuals and patients with inflammatory bowel disease: A pilot study. Genes, 12 (10). ISSN 2073-4425

Phillips, Sarah, Watt, Rachel, Atkinson, Thomas, Savva, George M., Hayhoe, Antonietta and Hall, Lindsay J. ORCID: https://orcid.org/0000-0001-8938-5709 and PEARL study team (2021) The Pregnancy and EARly Life study (PEARL) - A longitudinal study to understand how gut microbes contribute to maintaining health during pregnancy and early life. BMC Pediatrics, 21 (1). ISSN 1471-2431

Moriarty, Frank, Savva, George, Grossi, Carlota M., Bennett, Kathleen, Fox, Chris ORCID: https://orcid.org/0000-0001-9480-5704, Maidment, Ian, Loke, Yoon K., Steel, Nicholas ORCID: https://orcid.org/0000-0003-1528-140X, Kenny, Rose Anne and Richardson, Kathryn ORCID: https://orcid.org/0000-0002-0741-8413 (2021) Cognitive decline associated with anticholinergics, benzodiazepines, and Z‐drugs: findings from The Irish Longitudinal Study on Ageing (TILDA). British Journal of Pharmacology, 87 (7). pp. 2818-2829. ISSN 0007-1188

Romano, Stefano, Savva, George M., Bedarf, Janis R., Charles, Ian G., Hildebrand, Falk and Narbad, Arjan (2021) Meta-analysis of the Parkinson’s disease gut microbiome suggests alterations linked to intestinal inflammation. npj Parkinson's Disease, 7 (1). ISSN 2373-8057

Hynen, Amelia L., Lazenby, James J., Savva, George M., McCaughey, Laura C., Turnbull, Lynne, Nolan, Laura M. and Whitchurch, Cynthia B. ORCID: https://orcid.org/0000-0003-2296-3791 (2021) Multiple holins contribute to extracellular DNA release in Pseudomonas aeruginosa biofilms. Microbiology, 167 (2). ISSN 1350-0872

Trampari, Eleftheria, Holden, Emma R, Wickham, Gregory J, Ravi, Anuradha, Martins, Leonardo de Oliveira, Savva, George M and Webber, Mark A (2021) Exposure of Salmonella biofilms to antibiotic concentrations rapidly selects resistance with collateral tradeoffs. npj Biofilms and Microbiomes, 7 (1). ISSN 2055-5008

Richardson, Kathryn ORCID: https://orcid.org/0000-0002-0741-8413, Savva, George, Boyd, Penelope, Aldus, Clare ORCID: https://orcid.org/0000-0002-0197-2755, Maidment, Ian, Pakpahan, Eduwin, Loke, Yoon, Arthur, Antony, Steel, Nicholas ORCID: https://orcid.org/0000-0003-1528-140X, Ballard, Clive, Howard, Robert and Fox, Chris ORCID: https://orcid.org/0000-0001-9480-5704 (2021) Non-benzodiazepine hypnotic use for sleep disturbance in people aged over 55 years living with dementia: a series of cohort studies. Health Technology Assessment, 25 (1). pp. 1-202. ISSN 1366-5278

Richardson, Kathryn ORCID: https://orcid.org/0000-0002-0741-8413, Loke, Yoon K., Fox, Chris ORCID: https://orcid.org/0000-0001-9480-5704, Maidment, Ian, Howard, Robert, Steel, Nicholas ORCID: https://orcid.org/0000-0003-1528-140X, Arthur, Antony, Boyd, Penelope J., Aldus, Clare ORCID: https://orcid.org/0000-0002-0197-2755, Ballard, Clive and Savva, George M. (2020) Adverse effects of Z-drugs for sleep disturbance in people living with dementia: a population-based cohort study. BMC Medicine, 18. ISSN 1741-7015

Pieper, Nina T., Grossi, Carlota M., Chan, Wei-Yee, Loke, Yoon K., Savva, George M., Haroulis, Clara, Steel, Nicholas ORCID: https://orcid.org/0000-0003-1528-140X, Fox, Chris ORCID: https://orcid.org/0000-0001-9480-5704, Maidment, Ian D., Arthur, Antony J., Myint, Phyo K., Smith, Toby O. ORCID: https://orcid.org/0000-0003-1673-2954, Robinson, Louise, Matthews, Fiona E., Brayne, Carol and Richardson, Kathryn ORCID: https://orcid.org/0000-0002-0741-8413 (2020) Anticholinergic drugs and incident dementia, mild cognitive impairment and cognitive decline: a meta-analysis. Age and Ageing, 49 (6). 939–947. ISSN 0002-0729

Grossi, Carlota M., Richardson, Kathryn ORCID: https://orcid.org/0000-0002-0741-8413, Savva, George M., Fox, Chris ORCID: https://orcid.org/0000-0001-9480-5704, Arthur, Antony, Loke, Yoon K., Steel, Nicholas ORCID: https://orcid.org/0000-0003-1528-140X, Brayne, Carol, Matthews, Fiona E., Robinson, Louise, Myint, Phyo K. and Maidment, Ian D. (2020) Increasing prevalence of anticholinergic medication use in older people in England over 20 years: Cognitive Function and Ageing Study I and II. BMC Geriatrics, 20. ISSN 1471-2318

Page, Andrew J., Bastkowski, Sarah, Yasir, Muhammad, Turner, A Keith, Le Viet, Thanh, Savva, George M, Webber, Mark A and Charles, Ian G (2020) AlbaTraDIS:Comparative analysis of large datasets from parallel transposon mutagenesis experiments. PLoS Computational Biology, 16 (7). ISSN 1553-734X

Robertson, Claire, Savva, George M., Clapuci, Raducu, Jones, Jacqueline, Maimouni, Hassan, Brown, Eleanor, Minocha, Ashish, Hall, Lindsay J. ORCID: https://orcid.org/0000-0001-8938-5709 and Clarke, Paul ORCID: https://orcid.org/0000-0001-6203-7632 (2020) Incidence of necrotising enterocolitis before and after introducing routine prophylactic Lactobacillus and Bifidobacterium probiotics. Archives of Disease in Childhood: Fetal and Neonatal Edition, 105 (4). pp. 380-386. ISSN 1359-2998

Aldus, Clare ORCID: https://orcid.org/0000-0002-0197-2755, Arthur, Antony, Dennington-Price, Abigail, Millac, Paul, Richmond, Peter, Dening, Tom, Fox, Chris ORCID: https://orcid.org/0000-0001-9480-5704, Matthews, Fiona, Robinson, Louise, Stephan, Blossom C M, Brayne, Carol and Savva, George (2020) Undiagnosed dementia in primary care: A record linkage study. Health Services and Delivery Research, 8 (20). ISSN 2050-4349

Richardson, Kathryn ORCID: https://orcid.org/0000-0002-0741-8413, Wharton, Stephen B., Grossi, Carlota M., Matthews, Fiona E., Fox, Chris ORCID: https://orcid.org/0000-0001-9480-5704, Maidment, Ian, Loke, Yoon K., Steel, Nicholas ORCID: https://orcid.org/0000-0003-1528-140X, Arthur, Antony, Myint, Phyo Kyaw, Boustani, Malaz, Campbell, Noll, Robinson, Louise, Brayne, Carol and Savva, George M. (2020) Neuropathological correlates of cumulative benzodiazepine and anticholinergic drug use. Journal of Alzheimer's Disease, 74 (3). pp. 999-1009. ISSN 1387-2877

Yasir, Muhammad, Turner, A. Keith, Bastkowski, Sarah, Baker, David, Page, Andrew J., Telatin, Andrea, Phan, Minh-Duy, Monahan, Leigh, Savva, George M., Darling, Aaron, Webber, Mark A. and Charles, Ian G. (2020) TraDIS-Xpress: a high-resolution whole-genome assay identifies novel mechanisms of triclosan action and resistance. Genome Research, 30 (2). pp. 239-249. ISSN 1088-9051

Arthur, Antony, Savva, George, Barnes, Linda E., Borjian-Boroojeny, Ayda, Dening, Tom, Jagger, Carol, Matthews, Fiona E., Robinson, Louise and Brayne, Carol and Cognitive Function and Ageing Studies (CFAS) Collaboration (2020) Changing prevalence and treatment of depression among older people over two decades. The British Journal of Psychiatry, 216 (1). pp. 49-54. ISSN 0007-1250

Grossi, Carlota M., Richardson, Kathryn ORCID: https://orcid.org/0000-0002-0741-8413, Fox, Chris ORCID: https://orcid.org/0000-0001-9480-5704, Maidment, Ian, Steel, Nicholas ORCID: https://orcid.org/0000-0003-1528-140X, Loke, Yoon K., Arthur, Antony, Myint, Phyo Kyaw, Campbell, Noll, Boustani, Malaz, Robinson, Louise, Brayne, Carol, Matthews, Fiona E. and Savva, George M. (2019) Anticholinergic and benzodiazepine medication use and risk of incident dementia: a UK cohort study. BMC Geriatrics, 19. ISSN 1471-2318

Ravi, Anuradha, Halstead, Fenella D, Bamford, Amy, Casey, Anna, Thomson, Nicholas M, van Schaik, Willem, Snelson, Catherine, Goulden, Robert, Foster-Nyarko, Ebenezer, Savva, George M, Whitehouse, Tony, Pallen, Mark J ORCID: https://orcid.org/0000-0003-1807-3657 and Oppenheim, Beryl A (2019) Loss of microbial diversity and pathogen domination of the gut microbiota in critically ill patients. Microbial Genomics, 5 (9). ISSN 2057-5858

Mattishent, Katharina, Richardson, Kathryn ORCID: https://orcid.org/0000-0002-0741-8413, Dhatariya, Ketan, Savva, George, Fox, Chris ORCID: https://orcid.org/0000-0001-9480-5704 and Loke, Yoon (2019) The effects of hypoglycemia and dementia on cardiovascular events, falls and fractures and all-cause mortality in older people:a retrospective cohort study. Diabetes, Obesity & Metabolism, 21 (9). pp. 2076-2085. ISSN 1462-8902

Fox, Chris ORCID: https://orcid.org/0000-0001-9480-5704, Richardson, Kathryn, Savva, George M., Robinson, Louise, Maidment, Ian D., Loke, Yoon, Brayne, Carol, Mathews, Fiona, Ince, Paul, Wharton, Stephen, Myint, Phyo, Grossi, Carlota, Arthur, Antony, Steel, Nick, Boustani, Malaz A. and Campbell, Noll L. (2019) What are the effects of benzodiazepine and anticholinergic drug use on the brain: a neuropathological study. Alzheimer's and Dementia, 15 (7). P1232. ISSN 1552-5260

Sackley, Catherine M., Mant, Jonathan, McManus, Richard J., Humphries, Glyn, Sharp, Leslie, Mares, Kathryn ORCID: https://orcid.org/0000-0003-3923-4472 and Savva, George M. (2019) Functional and emotional outcomes after transient ischaemic attack: A 12-month prospective controlled cohort study. International Journal of Stroke, 14 (5). pp. 522-529. ISSN 1747-4930

Richardson, Kathryn ORCID: https://orcid.org/0000-0002-0741-8413, Mattishent, Katharina, Loke, Yoon, Steel, Nicholas ORCID: https://orcid.org/0000-0003-1528-140X, Fox, Chris ORCID: https://orcid.org/0000-0001-9480-5704, Grossi Sampedro, Carlota, Bennett, Kathleen, Maidment, Ian, Boustani, Malaz, Matthews, Fiona, Myint, Phyo, Campbell, Noll, Brayne, Carol, Robinson, Louise and Savva, George (2019) History of benzodiazepine prescriptions and risk of dementia: Possible bias due to prevalent users and covariate measurement timing in a nested case-control study. American Journal of Epidemiology, 188 (7). pp. 1228-1236. ISSN 0002-9262

Porter, Bryony, Arthur, Antony and Savva, George M (2019) How do potentially inappropriate medications and polypharmacy affect mortality in frail and non-frail cognitively impaired older adults?:A cohort study. BMJ Open, 9 (5). e026171. ISSN 2044-6055

Traka, Maria H, Melchini, Antonietta, Coode-Bate, Jack, Al Kadhi, Omar, Saha, Shikha, Defernez, Marianne, Troncoso-Rey, Perla, Kibblewhite, Helen, O'Neill, Carmel M, Bernuzzi, Federico, Mythen, Laura, Hughes, Jackie, Needs, Paul W, Dainty, Jack R ORCID: https://orcid.org/0000-0002-0056-1233, Savva, George M, Mills, Robert D, Ball, Richard Y, Cooper, Colin S ORCID: https://orcid.org/0000-0003-2013-8042 and Mithen, Richard F (2019) Transcriptional changes in prostate of men on active surveillance after a 12-mo glucoraphanin-rich broccoli intervention—results from the Effect of Sulforaphane on prostate CAncer PrEvention (ESCAPE) randomized controlled trial. The American Journal of Clinical Nutrition, 109 (4). pp. 1133-1144. ISSN 0002-9165

Le Gall, Gwénaëlle ORCID: https://orcid.org/0000-0002-1379-2196, Guttula, Kiran, Kellingray, Lee, Tett, Adrian J, ten Hoopen, Rogier, Kemsley, Kate E ORCID: https://orcid.org/0000-0003-0669-3883, Savva, George M, Ibrahim, Ashraf and Narbad, Arjan (2018) Metabolite quantification of faecal extracts from colorectal cancer patients and healthy controls. Oncotarget, 9 (70). pp. 33278-33289. ISSN 1949-2553

Mousa, Andria, Savva, George, Mitnitski, Arnold, Rockwood, Kenneth, Jagger, Carol, Brayne, Carol and Matthews, Fiona E. (2018) Is frailty a stable predictor of mortality across time? Evidence from the Cognitive Function and Ageing Studies. Age and Ageing, 47 (5). 721–727. ISSN 0002-0729

O'Connell, Matthew D. L., Savva, George M., Finucane, Ciarán, Romero-Ortuno, Roman, Fan, Chie Wei and Kenny, Rose Anne (2018) Impairments in hemodynamic responses to orthostasis associated with frailty: Results from TILDA. Journal of the American Geriatrics Society, 66 (8). pp. 1475-1483. ISSN 0002-8614

Richardson, Kathryn ORCID: https://orcid.org/0000-0002-0741-8413, Fox, Chris ORCID: https://orcid.org/0000-0001-9480-5704, Maidment, Ian, Steel, Nicholas ORCID: https://orcid.org/0000-0003-1528-140X, Loke, Yoon K, Arthur, Antony, Myint, Phyo K, Grossi, Carlota M, Mattishent, Katharina, Bennett, Kathleen, Campbell, Noll L, Boustani, Malaz, Robinson, Louise, Brayne, Carol, Matthews, Fiona E and Savva, George M (2018) Anticholinergic drugs and risk of dementia: case-control study. British Medical Journal, 361. ISSN 0959-8138

Stephan, Blossom C. M., Richardson, Kathryn ORCID: https://orcid.org/0000-0002-0741-8413, Savva, George M., Matthews, Fiona E., Brayne, Carol and Hackinski, Vladimir (2017) Potential value of impaired cognition in stroke prediction: A U.K. population-based study. Journal of the American Geriatrics Society, 65 (8). 1756–1762. ISSN 0002-8614

Finucane, Ciarán, O’Connell, Matthew DL, Donoghue, Orna, Richardson, Kathryn ORCID: https://orcid.org/0000-0002-0741-8413, Savva, George M. and Kenny, Rose Anne (2017) Impaired orthostatic blood pressure recovery is associated with unexplained and injurious falls. Journal of the American Geriatrics Society, 65 (3). 474–482. ISSN 0002-8614

Finucane, Ciarán, Savva, George M. and Kenny, Roseanne A. (2017) Reliability of orthostatic beat-to-beat blood pressure tests: implications for population and clinical studies. Clinical Autonomic Research, 27 (1). pp. 31-39. ISSN 0959-9851

Feeney, Joanne, Savva, George, O'Regan, Claire, King-Kallimanis, Bellinda, Cronin, Hilary and Kenny, Rose Anne (2016) Measurement error, reliability and minimum detectable change in MMSE, MoCA and Color Trails Test among community living middle aged and older adults. Journal of Alzheimer's Disease, 53 (3). pp. 1107-1114. ISSN 1387-2877

Mavaddat, Nahal, Van Der Linde, Rianne, Parker, Richard, Savva, George, Kinmonth, Ann Louise, Brayne, Carol and Mant, Jonathan (2016) Relationship of self-rated health to stroke incidence and mortality in older individuals with and without a history of stroke: A longitudinal study of the MRC Cognitive Function and Ageing (CFAS) population. PLoS One, 11 (2). ISSN 1932-6203

Vorontsova, Maria S, Besnard, Guillaume, Forest, Félix, Malakasi, Panagiota, Moat, Justin, Clayton, W. Derek, Ficinski, Paweł, Savva, George M., Nanjarisoa, Olinirina P., Razanatsoa, Jacqueline, Randriatsara, Fetra O., Kimeu, John M., Luke, W. R. Quentin, Kayombo, Canisius and Linder, H. Peter (2016) Madagascar's grasses and grasslands: anthropogenic or natural? Proceedings of the Royal Society B: Biological Sciences, 283 (1823). ISSN 0962-8452

Setti, Annalisa, Loughman, James, Savva, George M. and Kenny, RoseAnne (2015) Trail Making Test performance contributes to subjective judgment of visual efficiency in older adults. PeerJ, 3. ISSN 2167-8359

Robertson, Deirdre, Savva, George, King-Kallimanis, Bellinda and Kenny, Rose Anne (2015) Negative perceptions of aging and decline in walking speed: A self-fulfilling prophecy. PLoS One, 10 (4). ISSN 1932-6203

Ekonomou, Antigoni, Savva, George M., Brayne, Carol, Forster, Gillian, Francis, Paul T., Johnson, Mary, Perry, Elaine K., Attems, Johannes, Somani, Alyma, Minger, Stephen L. and Ballard, Clive G. (2015) Stage-Specific Changes in Neurogenic and Glial Markers in Alzheimer's Disease. Biological Psychiatry, 77 (8). 711–719. ISSN 0006-3223

O'Connell, Matthew D. L., Savva, George M., Fan, Chie Wei and Kenny, Rose Anne (2015) Orthostatic hypotension, orthostatic intolerance and frailty: The Irish Longitudinal Study on Aging-TILDA. Archives of Gerontology and Geriatrics, 60 (3). pp. 507-513. ISSN 0167-4943

Savva, George and Arthur, Antony (2015) Who has undiagnosed dementia? A cross-sectional analysis of participants of the Aging, Demographics and Memory Study. Age and Ageing, 44 (4). pp. 642-647. ISSN 0002-0729

Finucane, Ciarán, O'Connell, Matthew D L, Fan, Chie Wei, Savva, George M, Soraghan, Christopher J, Nolan, Hugh, Cronin, Hilary and Kenny, Rose Anne (2014) Age-related normative changes in phasic orthostatic blood pressure in a large population study:findings from The Irish Longitudinal Study on Ageing (TILDA). Circulation, 130 (20). pp. 1780-9. ISSN 0009-7322

Killane, Isabelle, Donoghue, Orna A, Savva, George M, Cronin, Hilary, Kenny, Rose Anne and Reilly, Richard B (2014) Relative association of processing speed, short-term memory and sustained attention with task on gait speed:a study of community-dwelling people 50 years and older. The Journals of Gerontology, Series A, 69 (11). pp. 1407-14. ISSN 1758-535X

Robertson, Deirdre A, Savva, George M, Coen, Robert F and Kenny, Rose-Anne (2014) Cognitive function in the prefrailty and frailty syndrome. Journal of the American Geriatrics Society, 62 (11). pp. 2118-24. ISSN 0002-8614

Donoghue, Orna A, Ryan, Harriet, Duggan, Eoin, Finucane, Ciaran, Savva, George M, Cronin, Hilary, Loughman, James and Kenny, Rose Anne (2014) Relationship between fear of falling and mobility varies with visual function among older adults. Geriatrics & Gerontology International, 14 (4). 827–836. ISSN 1447-0594

Donoghue, Orna A., Savva, George M., Cronin, Hilary, Kenny, Rose Anne and Horgan, N. Frances (2014) Using timed up and go and usual gait speed to predict incident disability in daily activities among community-dwelling adults aged 65 and older. Archives of Physical Medicine and Rehabilitation, 95 (10). 1954–1961. ISSN 0003-9993

King-Kallimanis, B.L., Kenny, R.A. and Savva, G.M. (2014) Factor structure for the frailty syndrome was consistent across Europe. Journal of Clinical Epidemiology, 67 (9). 1008–1015. ISSN 0895-4356

Hanly, Mark J., Savva, George M., Clifford, Ian and Whelan, Brendan J. (2014) Variation in incentive effects across neighbourhoods: An example from the Irish Longitudinal Study of ageing. Survey Research Methods, 8 (1). pp. 19-30. ISSN 1864-3361

Frewen, J., Savva, G.M., Boyle, G., Finucane, C. and Kenny, R.A. (2014) Cognitive performance in orthostatic hypotension:Findings from a nationally representative sample. Journal of the American Geriatrics Society, 62 (1). pp. 117-122. ISSN 0002-8614

Frewen, John, Finucane, Ciaran, Savva, George M, Boyle, Gerard and Kenny, Rose Anne (2014) Orthostatic hypotension is associated with lower cognitive performance in adults aged 50 plus with supine hypertension. The Journals of Gerontology, Series A, 69 (7). pp. 878-885. ISSN 1758-535X

O'Halloran, Aisling M., Finucane, Ciaran, Savva, George M., Robertson, Ian H. and Kenny, Rose Anne (2014) Sustained attention and frailty in the older adult population. The Journals of Gerontology, Series B, 69 (2). pp. 147-156. ISSN 1758-5368

Frewen, John, Finucane, Ciaran, Savva, George M, Boyle, Gerard, Coen, Robert F and Kenny, Rose Anne (2013) Cognitive function is associated with impaired heart rate variability in ageing adults:the Irish longitudinal study on ageing wave one results. Clinical Autonomic Research, 23 (6). ISSN 1619-1560

Regan, Claire O, Kearney, Patricia M, Savva, George, Cronin, Hilary and Kenny, Rose Anne (2013) Age and sex differences in prevalence and clinical correlates of depression:first results from the Irish Longitudinal Study on Ageing. International Journal of Geriatric Psychiatry, 28 (12). pp. 1280-1287. ISSN 1099-1166

Feeney, Joanne, Finucane, Ciarán, Savva, George, Cronin, Hilary, Beatty, Stephen, Nolan, John M and Kenny, Rose Anne (2013) Low macular pigment optical density is associated with lower cognitive performance in a large, population-based sample of older adults. Neurobiology of Aging, 34 (11). pp. 2449-2456. ISSN 1558-1497

O Regan, Claire, Kearney, Patricia M., Cronin, Hilary, Savva, George M., Lawlor, Brian A. and Kenny, Roseanne (2013) Oscillometric measure of blood pressure detects association between orthostatic hypotension and depression in population based study of older adults. BMC Psychiatry, 13. ISSN 1471-244X

Robertson, Deirdre A, Savva, George and Kenny, Rose Anne (2013) Frailty and cognitive impairment-A review of the evidence and causal mechanisms. Ageing Research Reviews, 12 (4). pp. 840-851. ISSN 1872-9649

Mavaddat, Nahal, Van der Linde, Rianne, Savva, George M, Brayne, Carol and Mant, Jonathan (2013) What determines the self-rated health of older individuals with stroke compared to other older individuals?:A cross-sectional analysis of the Medical Research Council Cognitive Function and Aging Study. BMC Geriatrics, 13. ISSN 1471-2318

Mavaddat, Nahal, Savva, George, Lasserson, Daniel S, Giles, Matthew F, Brayne, Carol and Mant, Jonathan (2013) Transient neurological symptoms in the older population:report of a prospective cohort study--the Medical Research Council Cognitive Function and Ageing Study (CFAS). BMJ Open, 3 (7). ISSN 2044-6055

Killane, Isabelle, Donoghue, Orna A, Savva, George M, Cronin, Hilary, Kenny, Rose Anne and Reilly, Richard B (2013) Variance between walking speed and neuropsychological test scores during three gait tasks across the irish longitudinal study on aging (TILDA) dataset. 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2013. pp. 6921-6924. ISSN 1557-170X

van der Linde, Rianne M, Stephan, Blossom C M, Matthews, Fiona E, Brayne, Carol and Savva, George M and Medical Research Council Cognitive Function and Ageing Study (2013) The presence of behavioural and psychological symptoms and progression to dementia in the cognitively impaired older population. International Journal of Geriatric Psychiatry, 28 (7). pp. 700-709. ISSN 0885-6230

McDaid, Olga, Hanly, Mark J, Richardson, Kathryn ORCID: https://orcid.org/0000-0002-0741-8413, Kee, Frank, Kenny, Rose Anne and Savva, George (2013) The effect of multiple chronic conditions on self-rated health, disability and quality of life among the older populations of Northern Ireland and the Republic of Ireland:a comparison of two nationally representative cross-sectional surveys. BMJ Open, 3 (6). ISSN 2044-6055

Savva, George, Pachnio, Annette, Kaul, Baksho, Morgan, Kevin, Huppert, Felicia A, Brayne, Carol and Moss, Paul A H and Medical Research Council Cognitive Function and Ageing Study (2013) Cytomegalovirus infection is associated with increased mortality in the older population. Aging Cell, 12 (3). pp. 381-387. ISSN 1474-9726

Gallagher, Damien, Savva, George, Kenny, RoseAnne and Lawlor, Brian A. (2013) What predicts persistent depression in older adults across Europe?:Utility of clinical and neuropsychological predictors from the SHARE study. Journal of Affective Disorders, 147 (1-3). pp. 192-197. ISSN 0165-0327

Donoghue, Orna A, Cronin, Hilary, Savva, George, O'Regan, Claire and Kenny, Rose Anne (2013) Effects of fear of falling and activity restriction on normal and dual task walking in community dwelling older adults. Gait & Posture, 38 (1). pp. 120-124.

Kenny, Rose Anne, Coen, Robert F, Frewen, John, Donoghue, Orna A, Cronin, Hilary and Savva, George (2013) Normative values of cognitive and physical function in older adults:findings from the Irish Longitudinal Study on Ageing. Journal of the American Geriatrics Society, 61 (Suppl S2). S279-S290. ISSN 0002-8614

Layte, Richard, Sexton, Eithne and Savva, George (2013) Quality of life in older age:evidence from an Irish cohort study. Journal of the American Geriatrics Society, 61 (Suppl 2). S299-305. ISSN 0002-8614

Savva, George, Maty, Siobhan C, Setti, Annalisa and Feeney, Joanne (2013) Cognitive and physical health of the older populations of England, the United States, and Ireland:international comparability of the Irish Longitudinal Study on Ageing. Journal of the American Geriatrics Society, 61 (Suppl S2). S291-S298. ISSN 0002-8614

Whelan, Brendan J and Savva, George (2013) Design and methodology of the Irish Longitudinal Study on Ageing. Journal of the American Geriatrics Society, 61 (Suppl S2). S265-S268. ISSN 0002-8614

Savva, George M, Donoghue, Orna A, Horgan, Frances, O'Regan, Claire, Cronin, Hilary and Kenny, Rose Anne (2013) Using timed up-and-go to identify frail members of the older population. The Journals of Gerontology, Series A, 68 (4). pp. 441-446. ISSN 1758-535X

Köhler, Sebastian, Allardyce, Judith, Verhey, Frans R J, McKeith, Ian G, Matthews, Fiona, Brayne, Carol and Savva, George M and Medical Research Council Cognitive Function and Ageing Study (2013) Cognitive decline and dementia risk in older adults with psychotic symptoms:a prospective cohort study. The American Journal of Geriatric Psychiatry, 21 (2). pp. 119-28. ISSN 1545-7214

Brayne, Carol, Barker, Roger A, Harold, Denise, Ince, Paul G, Savva, George M, Williams, Julie, Williams-Gray, Caroline H and Wharton, Stephen B (2013) From molecule to clinic and community for neurodegeneration:research to bridge translational gaps. Journal of Alzheimer's Disease, 33 (1). S385-96. ISSN 1875-8908

Gallagher, Damien, O'Regan, Claire, Savva, George M., Cronin, Hillary, Lawlor, Brian A. and Kenny, Rose A. (2012) Depression, anxiety and cardiovascular disease: Which symptoms are associated with increased risk in community dwelling older adults? Journal of Affective Disorders, 142 (1-3). pp. 132-138. ISSN 0165-0327

Nolan, John M, Feeney, Joanne, Kenny, Rose Anne, Cronin, Hilary, O'Regan, Claire, Savva, George M, Loughman, James, Finucane, Ciaran, Connolly, Eithne, Meagher, Katie and Beatty, Stephen (2012) Education is positively associated with macular pigment:the Irish Longitudinal Study on Ageing (TILDA). Investigative Ophthalmology & Visual Science, 53 (12). pp. 7855-7861. ISSN 1552-5783

Donoghue, Orna A, Horgan, N Frances, Savva, George M, Cronin, Hilary, O'Regan, Claire and Kenny, Rose Anne (2012) Association between timed up-and-go and memory, executive function, and processing speed. Journal of the American Geriatrics Society, 60 (9). pp. 1681-6. ISSN 0002-8614

Fan, Chie W, Savva, George M, Finucane, Ciaran, Cronin, Hilary, O'Regan, Claire and Kenny, Rose A and Irish Longitudinal Study on Ageing (2012) Factors affecting continuous beat-to-beat orthostatic blood pressure response in community-dwelling older adults. Blood Pressure Monitoring, 17 (4). pp. 160-163. ISSN 1473-5725

van der Linde, Rianne M, Stephan, Blossom C.M., Savva, George M, Dening, Tom and Brayne, Carol (2012) Systematic reviews on behavioural and psychological symptoms in the older or demented population. Alzheimer's Research & Therapy, 4 (4). p. 28. ISSN 1758-9193

Stone, Carol A, Lawlor, Peter G, Savva, George M, Bennett, Kathleen and Kenny, Rose Anne (2012) Prospective study of falls and risk factors for falls in adults with advanced cancer. Journal of Clinical Oncology, 30 (17). pp. 2128-33. ISSN 1527-7755

Lace, G, Ince, P G, Brayne, C, Savva, G M, Matthews, F E, de Silva, R, Simpson, J E and Wharton, S B (2012) Mesial temporal astrocyte tau pathology in the MRC-CFAS ageing brain cohort. Dementia and Geriatric Cognitive Disorders, 34 (1). pp. 15-24. ISSN 1421-9824

Stephan, Blossom C M, Matthews, Fiona E, Hunter, Sally, Savva, George M, Bond, John, McKeith, Ian G, Ince, Paul and Brayne, Carol and Medical Research Council Cognitive Function and Ageing Study (2012) Neuropathological profile of mild cognitive impairment from a population perspective. Alzheimer Disease and Associated Disorders, 26 (3). pp. 205-212. ISSN 0893-0341

Viggars, Andrew P, Wharton, Stephen B, Simpson, Julie E, Matthews, Fiona E, Brayne, Carol, Savva, George M, Garwood, Claire, Drew, David, Shaw, Pamela J and Ince, Paul G (2011) Alterations in the blood brain barrier in ageing cerebral cortex in relationship to Alzheimer-type pathology:a study in the MRC-CFAS population neuropathology cohort. Neuroscience Letters, 505 (1). pp. 25-30. ISSN 0304-3940

Fox, Chris ORCID: https://orcid.org/0000-0001-9480-5704, Richardson, Kathryn, Maidment, Ian D., Savva, George M., Matthews, Fiona E., Smithard, David, Coulton, Simon, Katona, Cornelius, Boustani, Malaz A. and Brayne, Carol (2011) Anticholinergic medication use and cognitive impairment in the older population: The medical research council cognitive function and ageing study. Journal of the American Geriatrics Society, 59 (8). pp. 1477-1483. ISSN 0002-8614

Kearney, Patricia M, Cronin, Hilary, O'Regan, Claire, Kamiya, Yumiko, Savva, George M, Whelan, Brendan and Kenny, Roseanne (2011) Cohort profile:the Irish Longitudinal Study on Ageing. International Journal of Epidemiology, 40 (4). pp. 877-884. ISSN 0300-5771

Stephan, Blossom C M, Brayne, Carol, Savva, George M and Matthews, Fiona E and Medical Research Council Cognitive Function and Ageing Study (2011) Occurrence of medical co-morbidity in mild cognitive impairment:implications for generalisation of MCI research. Age and Ageing, 40 (4). pp. 501-7. ISSN 0002-0729

Nicoll, J A R, Savva, G M, Stewart, J, Matthews, F E, Brayne, C and Ince, P and Medical Research Council Cognitive Function and Ageing Study (2011) Association between APOE genotype, neuropathology and dementia in the older population of England and Wales. Neuropathology and Applied Neurobiology, 37 (3). pp. 285-294. ISSN 1365-2990

Gebril, Ola H, Kirby, Janine, Savva, George, Brayne, Carol and Ince, Paul G (2011) HFE H63D, C282Y and AGTR1 A1166C polymorphisms and brain white matter lesions in the aging brain. Journal of Neurogenetics, 25 (1-2). pp. 7-14. ISSN 1563-5260

Tsopelas, Christos, Stewart, Robert, Savva, George M, Brayne, Carol, Ince, Paul, Thomas, Alan and Matthews, Fiona E and Medical Research Council Cognitive Function and Ageing Study (2011) Neuropathological correlates of late-life depression in older people. The British Journal of Psychiatry, 198 (2). pp. 109-114. ISSN 0007-1250

Wharton, Stephen B, Brayne, Carol, Savva, George M, Matthews, Fiona E, Forster, Gill, Simpson, Julie, Lace, Gemma and Ince, Paul G and Medical Research Council Cognitive Function and Ageing Study (2011) Epidemiological neuropathology:the MRC Cognitive Function and Aging Study experience. Journal of Alzheimer's Disease, 25 (2). pp. 359-72. ISSN 1875-8908

van der Linde, Rianne, Stephan, Blossom C M, Matthews, Fiona E, Brayne, Carol and Savva, George M and Medical Research Council Cognitive Function and Ageing Study (2010) Behavioural and psychological symptoms in the older population without dementia - relationship with socio-demographics, health and cognition. BMC Geriatrics, 10. ISSN 1471-2318

Stephan, Blossom C. M., Savva, George M., Brayne, Carol, Bond, John, McKeith, Ian G. and Matthews, Fiona E. and Medical Research Council Cognitive Function and Ageing Study (2010) Optimizing mild cognitive impairment for discriminating dementia risk in the general older population. The American Journal of Geriatric Psychiatry, 18 (8). pp. 662-673. ISSN 1545-7214

Eeles, Eamonn M P, Hubbard, Ruth E, White, Susan V, O'Mahony, M Sinead, Savva, George M and Bayer, Antony J (2010) Hospital use, institutionalisation and mortality associated with delirium. Age and Ageing, 39 (4). pp. 470-475. ISSN 0002-0729

Mc Donald, Jessica M, Savva, George M, Brayne, Carol, Welzel, Alfred T, Forster, Gill, Shankar, Ganesh M, Selkoe, Dennis J, Ince, Paul G and Walsh, Dominic M and Medical Research Council Cognitive Function and Ageing Study (2010) The presence of sodium dodecyl sulphate-stable Abeta dimers is strongly associated with Alzheimer-type dementia. Brain, 133 (5). pp. 1328-1341. ISSN 1460-2156

Simpson, J E, Ince, P G, Haynes, L J, Theaker, R, Gelsthorpe, C, Baxter, L, Forster, G, Lace, G L, Shaw, P J, Matthews, F E, Savva, G M, Brayne, C and Wharton, S B and MRC Cognitive Function and Ageing Neuropathology Study Group (2010) Population variation in oxidative stress and astrocyte DNA damage in relation to Alzheimer-type pathology in the ageing brain. Neuropathology and Applied Neurobiology, 36 (1). pp. 25-40. ISSN 1365-2990

Savva, George M and Stephan, Blossom C M and Alzheimer's Society Vascular Dementia Systematic Review Group (2010) Epidemiological studies of the effect of stroke on incident dementia:a systematic review. Stroke, 41 (1). e41-46. ISSN 1524-4628

Savva, George M, Walker, Kate and Morris, Joan K (2010) The maternal age-specific live birth prevalence of trisomies 13 and 18 compared to trisomy 21 (Down syndrome). Prenatal Diagnosis, 30 (1). pp. 57-64. ISSN 1097-0223

Hubbard, Ruth E, O'Mahony, M Sinead, Savva, George M, Calver, Brian L and Woodhouse, Ken W (2009) Inflammation and frailty measures in older people. Journal of Cellular and Molecular Medicine, 13 (9B). pp. 3103-3109. ISSN 1582-4934

Savva, George M, Wharton, Stephen B, Ince, Paul G, Forster, Gillian, Matthews, Fiona E and Brayne, Carol and Medical Research Council Cognitive Function and Ageing Study (2009) Age, neuropathology, and dementia. New England Journal of Medicine, 360 (22). pp. 2302-2309. ISSN 0028-4793

Lace, G, Savva, G M, Forster, G, de Silva, R, Brayne, C, Matthews, F E, Barclay, J J, Dakin, L, Ince, P G and Wharton, S B (2009) Hippocampal tau pathology is related to neuroanatomical connections: an ageing population-based study. Brain, 132 (5). pp. 1324-1334. ISSN 1460-2156

Savva, George M, Zaccai, Julia, Matthews, Fiona E, Davidson, Julie E, McKeith, Ian and Brayne, Carol and Medical Research Council Cognitive Function and Ageing Study (2009) Prevalence, correlates and course of behavioural and psychological symptoms of dementia in the population. The British Journal of Psychiatry, 194 (3). pp. 212-219. ISSN 0007-1250

Wharton, S B, O'Callaghan, J P, Savva, G M, Nicoll, J A R, Matthews, F, Simpson, J E, Forster, G, Shaw, P J, Brayne, C and Ince, P G and MRC Cognitive Function and Ageing Neuropathology Study Group (2009) Population variation in glial fibrillary acidic protein levels in brain ageing:relationship to Alzheimer-type pathology and dementia. Dementia and Geriatric Cognitive Disorders, 27 (5). pp. 465-473. ISSN 1421-9824

Morris, Joan K and Savva, George M (2008) The risk of fetal loss following a prenatal diagnosis of trisomy 13 or trisomy 18. American Journal of Medical Genetics Part A, 146A (7). pp. 827-832. ISSN 1552-4833

Davey, Robert, Savva, George, Dicks, Jo and Roberts, Ian N. (2007) MPP: a microarray-to-phylogeny pipeline for analysis of gene and marker content datasets. Bioinformatics, 23 (8). pp. 1023-1025. ISSN 1460-2059

Savva, George M, Morris, Joan K, Mutton, David E and Alberman, Eva (2006) Maternal age-specific fetal loss rates in Down syndrome pregnancies. Prenatal Diagnosis, 26 (6). pp. 499-504. ISSN 0197-3851

Savva, George, Conn, Jenn and Dicks, Jo (2004) Drawing phylogenetic trees in LATEX and Microsoft Word. Bioinformatics, 20 (14). pp. 2322-3. ISSN 1367-4803

Book Section

Werner, Perla, Savva, George, Maidment (Aston Uni), Ian D, Thyrian (Germany), Jochen Rene and Fox, George (2016) Dementia: Introduction, Epidemiology and Economic Impact. In: Mental Health and Older People. Springer, pp. 197-209. ISBN 978-3-319-29490-2