Items where Research Group is "Synthetic and Medicinal Chemistry

Article

Ahmadipour, Sanaz, Field, Robert A. ORCID: https://orcid.org/0000-0001-8574-0275 and Miller, Gavin J. (2021) Prospects for anti-Candida therapy through targeting the cell wall: A mini-review. The Cell Surface, 7. ISSN 2468-2330

Alkorbi, Faeza, Díaz-Moscoso, Alejandro, Gretton, Jacob, Chambrier, Isabelle, Tizzard, Graham J., Coles, Simon J., Hughes, David L. and Cammidge, Andrew N. ORCID: https://orcid.org/0000-0001-7912-4310 (2021) Complementary syntheses giving access to a full suite of differentially substituted phthalocyanine-porphyrin hybrids. Angewandte Chemie-International Edition, 60 (14). pp. 7632-7636. ISSN 1433-7851

Baker, Alexander N., Richards, Sarah-Jane, Pandey, Sarojini, Guy, Collette S., Ahmad, Ashfaq, Hasan, Muhammad, Biggs, Caroline I., Georgiou, Panagiotis G., Zwetsloot, Alexander J., Straube, Anne, Dedola, Simone, Field, Robert A. ORCID: https://orcid.org/0000-0001-8574-0275, Anderson, Neil R., Walker, Marc, Grammatopoulos, Dimitris and Gibson, Matthew I. (2021) Glycan-based flow-through device for the detection of SARS-COV-2. ACS Sensors, 6 (10). pp. 3696-3705. ISSN 2379-3694

Bergua, Fernando, Delso, Ignacio ORCID: https://orcid.org/0000-0001-8355-2289, Muñoz-Embid, José, Lafuente, Carlos and Artal, Manuela (2021) Structure and properties of two glucose-based deep eutectic systems. Food Chemistry, 336. ISSN 0308-8146

Bulmer, Gregory S., de Andrade, Peterson, Field, Robert A. ORCID: https://orcid.org/0000-0001-8574-0275 and van Munster, Jolanda M. (2021) Recent advances in enzymatic synthesis of β-glucan and cellulose. Carbohydrate Research, 508. ISSN 0008-6215

Charoenwongpaiboon, Thanapon, Wangpaiboon, Karan, Pichyangkura, Rath, Nepogodiev, Sergey A., Wonganan, Piyanuch, Mahalapbutr, Panupong and Field, Robert A. ORCID: https://orcid.org/0000-0001-8574-0275 (2021) Characterization of a nanoparticulate exopolysaccharide from Leuconostoc holzapfelii KM01 and its potential application in drug encapsulation. International Journal of Biological Macromolecules, 187. pp. 690-698. ISSN 0141-8130

Furze, Christopher M., Delso, Ignacio ORCID: https://orcid.org/0000-0001-8355-2289, Casal, Enriqueta, Guy, Collette S., Seddon, Chloe, Brown, Chelsea M., Parker, Hadyn L., Radhakrishnan, Anjana, Pacheco-Gomez, Raul, Stansfeld, Phillip J., Angulo, Jesus ORCID: https://orcid.org/0000-0001-7250-5639, Cameron, Alexander D. and Fullam, Elizabeth (2021) Structural basis of trehalose recognition by the mycobacterial LpqY-SugABC transporter. Journal of Biological Chemistry, 296. ISSN 0021-9258

Gabrielli, Valeria, Muñoz-García, Juan Carlos, Pergolizzi, Giulia, De Andrade, Peterson, Khimyak, Yaroslav ORCID: https://orcid.org/0000-0003-0424-4128, Field, Robert A ORCID: https://orcid.org/0000-0001-8574-0275 and Angulo, Jesus ORCID: https://orcid.org/0000-0001-7250-5639 (2021) Molecular recognition of natural and non‐natural substrates by cellodextrin phosphorylase from Ruminiclostridium thermocellum investigated by NMR spectroscopy. Chemistry – A European Journal, 27 (63). pp. 15688-15698. ISSN 0947-6539

García-García, Ana, Serna, Sonia, Yang, Zhang, Delso, Ignacio ORCID: https://orcid.org/0000-0001-8355-2289, Taleb, Víctor, Hicks, Thomas, Artschwager, Raik, Vakhrushev, Sergey Y., Clausen, Henrik, Angulo, Jesús ORCID: https://orcid.org/0000-0001-7250-5639, Corzana, Francisco, Reichardt, Niels C. and Hurtado-Guerrero, Ramon (2021) FUT8-directed core fucosylation of N-glycans is regulated by the glycan structure and protein environment. ACS Catalysis, 11 (15). pp. 9052-9065. ISSN 2155-5435

Goddard, Zoë Rachael ORCID: https://orcid.org/0000-0002-7900-1553, Beekman, Andrew Michael ORCID: https://orcid.org/0000-0002-3056-6406, Cominetti, Marco M. D., O'Connell, Maria A. ORCID: https://orcid.org/0000-0002-0267-0951, Chambrier, Isabelle, Cook, Michael J., Marin, Maria J. ORCID: https://orcid.org/0000-0001-8021-5498, Russell, David A. and Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949 (2021) Peptide directed phthalocyanine-gold nanoparticles for selective photodynamic therapy of EGFR overexpressing cancers. RSC Medicinal Chemistry, 12 (2). pp. 288-292. ISSN 2632-8682

Hernando, Pedro J., Dedola, Simone, Marin, Maria J. ORCID: https://orcid.org/0000-0001-8021-5498 and Field, Robert ORCID: https://orcid.org/0000-0001-8574-0275 (2021) Recent developments in the use of glyconanoparticles and related quantum dots for the detection of lectins, viruses, bacteria and cancer cells. Frontiers in Chemistry, 9. ISSN 2296-2646

Howell, Lesley Ann and Beekman, Andrew Michael ORCID: https://orcid.org/0000-0002-3056-6406 (2021) In silico peptide-directed ligand design complements experimental peptide-directed binding for protein–protein interaction modulator discovery. RSC Chemical Biology, 2 (1). pp. 215-219. ISSN 2633-0679

Latorre-Muro, Pedro, Baeza, Josue, Hurtado-Guerrero, Ramon, Hicks, Thomas, Delso, Ignacio ORCID: https://orcid.org/0000-0001-8355-2289, Hernández-Ruiz, Cristina, Velázquez-Campoy, Adrian, Lawton, Alexis J., Angulo, Jesús ORCID: https://orcid.org/0000-0001-7250-5639, Denu, John M. and Carrodeguas, José A. (2021) Self-acetylation at the active site of phosphoenolpyruvate carboxykinase (PCK1) controls enzyme activity. Journal of Biological Chemistry, 296. ISSN 0021-9258

M. M. D. Cominetti, Marco, Goddard, Zoë R. ORCID: https://orcid.org/0000-0002-7900-1553, Howman, Chloe E., O'Connell, Maria A. ORCID: https://orcid.org/0000-0002-0267-0951 and Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949 (2021) Amino DSA analogues as payloads for antibody-drug conjugates with multiple sites for conjugation. Initial studies and solid phase synthesis. Tetrahedron Letters, 72. ISSN 0040-4039

Nadzirin, Izzuddin Bin, Fortuny‐Gomez, Anna, Ngum, Neville, Richards, David, Ali, Seema, Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949 and Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548 (2021) Taspine is a natural product that suppresses P2X4 receptor activity via phosphoinositide 3‐kinase inhibition. British Journal of Pharmacology, 178 (24). pp. 4859-4872. ISSN 0007-1188

Nigmatullin, Rinat, de Andrade, Peterson, Harniman, Robert, Field, Robert A. ORCID: https://orcid.org/0000-0001-8574-0275 and Eichhorn, Stephen J. (2021) Postsynthesis self- and coassembly of enzymatically produced fluorinated cellodextrins and cellulose nanocrystals. Langmuir, 37 (30). pp. 9215-9221. ISSN 0743-7463

Ortuzar, Natalia, Karu, Kersti, Presa, Daniela, Morais, Goreti R., Sheldrake, Helen M., Shnyder, Steve D., Barnieh, Francis M., Loadman, Paul M., Patterson, Laurence H., Pors, Klaus and Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949 (2021) Probing cytochrome P450 (CYP) bioactivation with chloromethylindoline bioprecursors derived from the duocarmycin family of compounds. Bioorganic & Medicinal Chemistry, 40. ISSN 0968-0896

O’Sullivan, Michael J., Hatley, Richard J. D., Wellaway, Christopher R., Bew, Sean P. ORCID: https://orcid.org/0000-0002-9087-9463 and Richards, Christopher J. ORCID: https://orcid.org/0000-0001-7899-4082 (2021) Synthetic approaches to N- and 4-substituted 1,4-dihydro-3(2H)-isoquinolinone derivatives. Tetrahedron, 100. ISSN 0040-4020

Piyasirananda, Waraporn, Beekman, Andrew ORCID: https://orcid.org/0000-0002-3056-6406, Ganesan, A., Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138 and Stokes, Leanne ORCID: https://orcid.org/0000-0003-4013-6781 (2021) Insights into the structure-activity relationship of glycosides as positive allosteric modulators acting on P2X7 receptors. Molecular Pharmacology, 99 (2). pp. 163-174. ISSN 0026-895X

Roy, Palas, Bressan, Giovanni ORCID: https://orcid.org/0000-0001-7801-8495, Gretton, Jacob, Cammidge, Andrew N. ORCID: https://orcid.org/0000-0001-7912-4310 and Meech, Stephen R. ORCID: https://orcid.org/0000-0001-5561-2782 (2021) Ultrafast excimer formation and solvent controlled symmetry breaking charge separation in the excitonically coupled subphthalocyanine dimer. Angewandte Chemie-International Edition, 60 (19). pp. 10568-10572. ISSN 1433-7851

Stokes, Leanne ORCID: https://orcid.org/0000-0003-4013-6781, Bielecka, Hanna, Felgate, Matthew, Beekman, Andrew ORCID: https://orcid.org/0000-0002-3056-6406, Ngameni, Bathelemy, Chi, Godloves Fru, Stephenson, Richard and Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138 (2021) Dioscin-related glycosides as positive allosteric modulators of P2X7 receptors. British Journal of Pharmacology, 178 (24). p. 4947. ISSN 0007-1188

Wagstaff, Ben A., Pratscher, Jennifer, Rivera, Peter Paolo L., Hems, Edward S., Brooks, Elliot, Rejzek, Martin, Todd, Jonathan D., Murrell, J. Colin and Field, Robert A. ORCID: https://orcid.org/0000-0001-8574-0275 (2021) Assessing the toxicity and mitigating the impact of harmful Prymnesium blooms in eutrophic waters of the Norfolk Broads. Environmental Science & Technology, 55 (24). 16538–16551. ISSN 0013-936X

Wright, Mark A., O'Connell, Maria A. ORCID: https://orcid.org/0000-0002-0267-0951 and Wright, Joseph A. ORCID: https://orcid.org/0000-0001-9603-1001 (2021) Ruthenium carbamoyl complexes: coordination chemistry and CO release. Inorganica Chimica Acta, 520. ISSN 0020-1693

de Andrade, Peterson, Muñoz-García, Juan C., Pergolizzi, Giulia, Gabrielli, Valeria, Nepogodiev, Sergey, Iuga, Dinu, Fabian, Laszlo, Nigmatullin, Rinat, Johns, Marcus A., Harniman, Robert, Eichhorn, Stephen J., Angulo Alvarez, Jesus ORCID: https://orcid.org/0000-0001-7250-5639, Khimyak, Yaroslav ORCID: https://orcid.org/0000-0003-0424-4128 and Field, Robert ORCID: https://orcid.org/0000-0001-8574-0275 (2021) Chemoenzymatic synthesis of fluorinated cellodextrins identifies a new allomorph for cellulose‐like materials. Chemistry - A European Journal, 27 (4). pp. 1374-1382. ISSN 0947-6539