Items where Research Group is "Synthetic and Medicinal Chemistry

A

Ahmadipour, Sanaz, Field, Robert A. ORCID: https://orcid.org/0000-0001-8574-0275 and Miller, Gavin J. (2021) Prospects for anti-Candida therapy through targeting the cell wall: A mini-review. The Cell Surface, 7. ISSN 2468-2330

Alkorbi, Faeza, Díaz-Moscoso, Alejandro, Gretton, Jacob, Chambrier, Isabelle, Tizzard, Graham J., Coles, Simon J., Hughes, David L. and Cammidge, Andrew N. ORCID: https://orcid.org/0000-0001-7912-4310 (2021) Complementary syntheses giving access to a full suite of differentially substituted phthalocyanine-porphyrin hybrids. Angewandte Chemie-International Edition, 60 (14). pp. 7632-7636. ISSN 1433-7851

B

Baker, Alexander N., Richards, Sarah-Jane, Pandey, Sarojini, Guy, Collette S., Ahmad, Ashfaq, Hasan, Muhammad, Biggs, Caroline I., Georgiou, Panagiotis G., Zwetsloot, Alexander J., Straube, Anne, Dedola, Simone, Field, Robert A. ORCID: https://orcid.org/0000-0001-8574-0275, Anderson, Neil R., Walker, Marc, Grammatopoulos, Dimitris and Gibson, Matthew I. (2021) Glycan-based flow-through device for the detection of SARS-COV-2. ACS Sensors, 6 (10). pp. 3696-3705. ISSN 2379-3694

Bergua, Fernando, Delso, Ignacio ORCID: https://orcid.org/0000-0001-8355-2289, Muñoz-Embid, José, Lafuente, Carlos and Artal, Manuela (2021) Structure and properties of two glucose-based deep eutectic systems. Food Chemistry, 336. ISSN 0308-8146

Bulmer, Gregory S., de Andrade, Peterson, Field, Robert A. ORCID: https://orcid.org/0000-0001-8574-0275 and van Munster, Jolanda M. (2021) Recent advances in enzymatic synthesis of β-glucan and cellulose. Carbohydrate Research, 508. ISSN 0008-6215

C

Charoenwongpaiboon, Thanapon, Wangpaiboon, Karan, Pichyangkura, Rath, Nepogodiev, Sergey A., Wonganan, Piyanuch, Mahalapbutr, Panupong and Field, Robert A. ORCID: https://orcid.org/0000-0001-8574-0275 (2021) Characterization of a nanoparticulate exopolysaccharide from Leuconostoc holzapfelii KM01 and its potential application in drug encapsulation. International Journal of Biological Macromolecules, 187. pp. 690-698. ISSN 0141-8130

D

de Andrade, Peterson, Muñoz-García, Juan C., Pergolizzi, Giulia, Gabrielli, Valeria, Nepogodiev, Sergey, Iuga, Dinu, Fabian, Laszlo, Nigmatullin, Rinat, Johns, Marcus A., Harniman, Robert, Eichhorn, Stephen J., Angulo Alvarez, Jesus ORCID: https://orcid.org/0000-0001-7250-5639, Khimyak, Yaroslav ORCID: https://orcid.org/0000-0003-0424-4128 and Field, Robert ORCID: https://orcid.org/0000-0001-8574-0275 (2021) Chemoenzymatic synthesis of fluorinated cellodextrins identifies a new allomorph for cellulose‐like materials. Chemistry - A European Journal, 27 (4). pp. 1374-1382. ISSN 0947-6539

F

Furze, Christopher M., Delso, Ignacio ORCID: https://orcid.org/0000-0001-8355-2289, Casal, Enriqueta, Guy, Collette S., Seddon, Chloe, Brown, Chelsea M., Parker, Hadyn L., Radhakrishnan, Anjana, Pacheco-Gomez, Raul, Stansfeld, Phillip J., Angulo, Jesus ORCID: https://orcid.org/0000-0001-7250-5639, Cameron, Alexander D. and Fullam, Elizabeth (2021) Structural basis of trehalose recognition by the mycobacterial LpqY-SugABC transporter. Journal of Biological Chemistry, 296. ISSN 0021-9258

G

Gabrielli, Valeria, Muñoz-García, Juan Carlos, Pergolizzi, Giulia, De Andrade, Peterson, Khimyak, Yaroslav ORCID: https://orcid.org/0000-0003-0424-4128, Field, Robert A ORCID: https://orcid.org/0000-0001-8574-0275 and Angulo, Jesus ORCID: https://orcid.org/0000-0001-7250-5639 (2021) Molecular recognition of natural and non‐natural substrates by cellodextrin phosphorylase from Ruminiclostridium thermocellum investigated by NMR spectroscopy. Chemistry – A European Journal, 27 (63). pp. 15688-15698. ISSN 0947-6539

García-García, Ana, Serna, Sonia, Yang, Zhang, Delso, Ignacio ORCID: https://orcid.org/0000-0001-8355-2289, Taleb, Víctor, Hicks, Thomas, Artschwager, Raik, Vakhrushev, Sergey Y., Clausen, Henrik, Angulo, Jesús ORCID: https://orcid.org/0000-0001-7250-5639, Corzana, Francisco, Reichardt, Niels C. and Hurtado-Guerrero, Ramon (2021) FUT8-directed core fucosylation of N-glycans is regulated by the glycan structure and protein environment. ACS Catalysis, 11 (15). pp. 9052-9065. ISSN 2155-5435

Goddard, Zoë Rachael ORCID: https://orcid.org/0000-0002-7900-1553, Beekman, Andrew Michael ORCID: https://orcid.org/0000-0002-3056-6406, Cominetti, Marco M. D., O'Connell, Maria A. ORCID: https://orcid.org/0000-0002-0267-0951, Chambrier, Isabelle, Cook, Michael J., Marin, Maria J. ORCID: https://orcid.org/0000-0001-8021-5498, Russell, David A. and Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949 (2021) Peptide directed phthalocyanine-gold nanoparticles for selective photodynamic therapy of EGFR overexpressing cancers. RSC Medicinal Chemistry, 12 (2). pp. 288-292. ISSN 2632-8682

H

Hernando, Pedro J., Dedola, Simone, Marin, Maria J. ORCID: https://orcid.org/0000-0001-8021-5498 and Field, Robert ORCID: https://orcid.org/0000-0001-8574-0275 (2021) Recent developments in the use of glyconanoparticles and related quantum dots for the detection of lectins, viruses, bacteria and cancer cells. Frontiers in Chemistry, 9. ISSN 2296-2646

Howell, Lesley Ann and Beekman, Andrew Michael ORCID: https://orcid.org/0000-0002-3056-6406 (2021) In silico peptide-directed ligand design complements experimental peptide-directed binding for protein–protein interaction modulator discovery. RSC Chemical Biology, 2 (1). pp. 215-219. ISSN 2633-0679

L

Latorre-Muro, Pedro, Baeza, Josue, Hurtado-Guerrero, Ramon, Hicks, Thomas, Delso, Ignacio ORCID: https://orcid.org/0000-0001-8355-2289, Hernández-Ruiz, Cristina, Velázquez-Campoy, Adrian, Lawton, Alexis J., Angulo, Jesús ORCID: https://orcid.org/0000-0001-7250-5639, Denu, John M. and Carrodeguas, José A. (2021) Self-acetylation at the active site of phosphoenolpyruvate carboxykinase (PCK1) controls enzyme activity. Journal of Biological Chemistry, 296. ISSN 0021-9258

M

M. M. D. Cominetti, Marco, Goddard, Zoë R. ORCID: https://orcid.org/0000-0002-7900-1553, Howman, Chloe E., O'Connell, Maria A. ORCID: https://orcid.org/0000-0002-0267-0951 and Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949 (2021) Amino DSA analogues as payloads for antibody-drug conjugates with multiple sites for conjugation. Initial studies and solid phase synthesis. Tetrahedron Letters, 72. ISSN 0040-4039

N

Nadzirin, Izzuddin Bin, Fortuny‐Gomez, Anna, Ngum, Neville, Richards, David, Ali, Seema, Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949 and Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548 (2021) Taspine is a natural product that suppresses P2X4 receptor activity via phosphoinositide 3‐kinase inhibition. British Journal of Pharmacology, 178 (24). pp. 4859-4872. ISSN 0007-1188

Nigmatullin, Rinat, de Andrade, Peterson, Harniman, Robert, Field, Robert A. ORCID: https://orcid.org/0000-0001-8574-0275 and Eichhorn, Stephen J. (2021) Postsynthesis self- and coassembly of enzymatically produced fluorinated cellodextrins and cellulose nanocrystals. Langmuir, 37 (30). pp. 9215-9221. ISSN 0743-7463

O

Ortuzar, Natalia, Karu, Kersti, Presa, Daniela, Morais, Goreti R., Sheldrake, Helen M., Shnyder, Steve D., Barnieh, Francis M., Loadman, Paul M., Patterson, Laurence H., Pors, Klaus and Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949 (2021) Probing cytochrome P450 (CYP) bioactivation with chloromethylindoline bioprecursors derived from the duocarmycin family of compounds. Bioorganic & Medicinal Chemistry, 40. ISSN 0968-0896

O’Sullivan, Michael J., Hatley, Richard J. D., Wellaway, Christopher R., Bew, Sean P. ORCID: https://orcid.org/0000-0002-9087-9463 and Richards, Christopher J. ORCID: https://orcid.org/0000-0001-7899-4082 (2021) Synthetic approaches to N- and 4-substituted 1,4-dihydro-3(2H)-isoquinolinone derivatives. Tetrahedron, 100. ISSN 0040-4020

P

Piyasirananda, Waraporn, Beekman, Andrew ORCID: https://orcid.org/0000-0002-3056-6406, Ganesan, A., Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138 and Stokes, Leanne ORCID: https://orcid.org/0000-0003-4013-6781 (2021) Insights into the structure-activity relationship of glycosides as positive allosteric modulators acting on P2X7 receptors. Molecular Pharmacology, 99 (2). pp. 163-174. ISSN 0026-895X

R

Roy, Palas, Bressan, Giovanni ORCID: https://orcid.org/0000-0001-7801-8495, Gretton, Jacob, Cammidge, Andrew N. ORCID: https://orcid.org/0000-0001-7912-4310 and Meech, Stephen R. ORCID: https://orcid.org/0000-0001-5561-2782 (2021) Ultrafast excimer formation and solvent controlled symmetry breaking charge separation in the excitonically coupled subphthalocyanine dimer. Angewandte Chemie-International Edition, 60 (19). pp. 10568-10572. ISSN 1433-7851

S

Stokes, Leanne ORCID: https://orcid.org/0000-0003-4013-6781, Bielecka, Hanna, Felgate, Matthew, Beekman, Andrew ORCID: https://orcid.org/0000-0002-3056-6406, Ngameni, Bathelemy, Chi, Godloves Fru, Stephenson, Richard and Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138 (2021) Dioscin-related glycosides as positive allosteric modulators of P2X7 receptors. British Journal of Pharmacology, 178 (24). p. 4947. ISSN 0007-1188

W

Wagstaff, Ben A., Pratscher, Jennifer, Rivera, Peter Paolo L., Hems, Edward S., Brooks, Elliot, Rejzek, Martin, Todd, Jonathan D., Murrell, J. Colin and Field, Robert A. ORCID: https://orcid.org/0000-0001-8574-0275 (2021) Assessing the toxicity and mitigating the impact of harmful Prymnesium blooms in eutrophic waters of the Norfolk Broads. Environmental Science & Technology, 55 (24). 16538–16551. ISSN 0013-936X

Wright, Mark A., O'Connell, Maria A. ORCID: https://orcid.org/0000-0002-0267-0951 and Wright, Joseph A. ORCID: https://orcid.org/0000-0001-9603-1001 (2021) Ruthenium carbamoyl complexes: coordination chemistry and CO release. Inorganica Chimica Acta, 520. ISSN 0020-1693