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Hernando, Pedro J., Dedola, Simone, Marin, Maria J. 
ORCID: https://orcid.org/0000-0001-8021-5498 and Field, Robert A.
(2021)
Recent developments in the use of glyconanoparticles and related quantum dots for the detection of lectins, viruses, bacteria and cancer cells.
Frontiers in Chemistry, 9.
ISSN 2296-2646
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Abstract
Carbohydrate-coated nanoparticles – glyconanoparticles – are finding increased interest as tools in biomedicine. This compilation, mainly covering the past five years, comprises the use of gold, silver and ferrite (magnetic) nanoparticles, silicon-based and cadmium-based quantum dots. Applications in the detection of lectins/protein toxins, viruses and bacteria are covered, as well as advances in detection of cancer cells. The role of the carbohydrate moieties in stabilising nanoparticles and providing selectivity in bioassays is discussed, the issue of cytotoxicity encountered in some systems, especially semiconductor quantum dots, is also considered. Efforts to overcome the latter problem by using other types of nanoparticles, based on gold or silicon, are also presented.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | cancer imaging,glycobiology,glyconanoparticles,gold nanoparticles,pathogen detection,rapid diagnostics,chemistry(all),sdg 3 - good health and well-being ,/dk/atira/pure/subjectarea/asjc/1600 |
| Faculty \ School: | Faculty of Science > School of Chemistry |
| UEA Research Groups: | Faculty of Science > Research Groups > Chemistry of Materials and Catalysis Faculty of Science > Research Groups > Chemistry of Light and Energy Faculty of Science > Research Groups > Chemistry of Life Processes |
| Related URLs: | |
| Depositing User: | LivePure Connector |
| Date Deposited: | 11 Jul 2021 00:14 |
| Last Modified: | 23 Oct 2022 02:36 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/80528 |
| DOI: | 10.3389/fchem.2021.668509 |
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