Items where Research Group is "Synthetic and Medicinal Chemistry

A

Andriotis, Vasilios M. E., Rejzek, Martin, Barclay, Elaine, Rugen, Michael D., Field, Robert A. ORCID: https://orcid.org/0000-0001-8574-0275 and Smith, Alison M. (2016) Cell wall degradation is required for normal starch mobilisation in barley endosperm. Scientific Reports, 6. ISSN 2045-2322

Andriotis, Vasilios M. E., Rejzek, Martin, Rugen, Michael D., Svensson, Birte, Smith, Alison M. and Field, Robert A. ORCID: https://orcid.org/0000-0001-8574-0275 (2016) Iminosugar inhibitors of carbohydrate-active enzymes that underpin cereal grain germination and endosperm metabolism. Biochemical Society Transactions, 44 (1). pp. 159-165. ISSN 0300-5127

Andriotis, Vasilios M. E., Saalbach, Gerhard, Waugh, Robbie, Field, Robert A. ORCID: https://orcid.org/0000-0001-8574-0275 and Smith, Alison M. (2016) The maltase involved in starch metabolism in barley endosperm is encoded by a single gene. PLoS One, 11 (3). ISSN 1932-6203

Angulo, Jesus ORCID: https://orcid.org/0000-0001-7250-5639, Goffin, Sarah, Gandhi, Daivik, Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949 and Howell, Lesley (2016) Unveiling the "three finger pharmacophore" required for p53-MDM2 inhibition by saturation transfer difference NMR initial growth rates approach. Chemistry - A European Journal, 22 (17). pp. 5858-5862. ISSN 0947-6539

Anwar, Awais, Gould, Emma, Tinson, Ryan, Groom, Murree and Hamilton, Chris J. (2016) Think yellow and keep green—Role of sulfanes from garlic in agriculture. Antioxidants, 6 (1). ISSN 2076-3921

Austin, Michael J., Hearnshaw, Stephen J., Mitchenall, Lesley A., McDermott, Paul J., Howell, Lesley A., Maxwell, Anthony and Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949 (2016) A natural product inspired fragment-based approach towards the development of novel anti-bacterial agents. MedChemComm, 7 (7). pp. 1387-1391. ISSN 2040-2503

B

Beekman, Andrew M. ORCID: https://orcid.org/0000-0002-3056-6406, O'Connell, Maria A. ORCID: https://orcid.org/0000-0002-0267-0951 and Howell, Lesley A. (2016) Identification of small-molecule inhibitors of the antiapoptotic protein myeloid cell leukaemia-1 (Mcl-1). ChemMedChem, 11 (8). 840–844. ISSN 1860-7179

Bew, Sean ORCID: https://orcid.org/0000-0002-9087-9463, Hiatt-Gipson, Glyn D., Mills, Graham P. and Reeves, Claire ORCID: https://orcid.org/0000-0003-4071-1926 (2016) Efficient syntheses of climate relevant isoprene nitrates and (1R,5S)-(−)-myrtenol nitrate. Beilstein Journal of Organic Chemistry, 12. pp. 1081-1095. ISSN 1860-5397

Bew, Sean P. ORCID: https://orcid.org/0000-0002-9087-9463, Bachera, Dominika U., Coles, Simon J., Hiatt-Gipson, Glyn D., Pesce, Paolo, Pitak, Mateusz, Thurston, Sean M. and Zdorichenko, Victor (2016) “Dial Up and Lock In”: Asymmetric organo-Brønsted acid catalysis incorporating stable isotopes. Chem, 1 (6). 921–945. ISSN 2451-9294

F

Fritzsch, Robby, Brady, Owen, Adair, Elaine, Wright, Joseph A. ORCID: https://orcid.org/0000-0001-9603-1001, Pickett, Christopher J. and Hunt, Neil T. (2016) Encapsulating subsite analogues of the [FeFe]-hydrogenases in micelles enables direct water interactions. The Journal of Physical Chemistry Letters, 7 (14). pp. 2838-2843. ISSN 1948-7185

G

Goetz, Stephan, Rejzek, Martin, Nepogodiev, Sergey A. and Field, Robert A. ORCID: https://orcid.org/0000-0001-8574-0275 (2016) The impact of aminopyrene trisulfonate (APTS) label in acceptor glycan substrates for profiling plant pectin β-galactosyltransferase activities. Carbohydrate Research, 433. pp. 97-105. ISSN 0008-6215

H

He, Xiao Peng, Zeng, Ya Li, Zang, Yi, Li, Jia, Field, Robert A. ORCID: https://orcid.org/0000-0001-8574-0275 and Chen, Guo Rong (2016) Carbohydrate CuAAC click chemistry for therapy and diagnosis. Carbohydrate Research, 429. pp. 1-22. ISSN 0008-6215

Howell, Lesley and Beekman, Andrew ORCID: https://orcid.org/0000-0002-3056-6406 (2016) Small molecule and peptide inhibitors of the pro-survival protein Mcl-1. ChemMedChem, 11 (8). 802–813. ISSN 1860-7179

Hunt, Neil T., Wright, Joseph A. ORCID: https://orcid.org/0000-0001-9603-1001 and Pickett, Christopher (2016) Detection of transient intermediates generated from subsite analogues of [FeFe]-hydrogenases. Inorganic Chemistry, 55 (2). pp. 399-410. ISSN 0020-1669

K

Kay, Kristine L., Hamilton, Chris J. and Le Brun, Nick E. ORCID: https://orcid.org/0000-0001-9780-4061 (2016) Mass spectrometry of B. subtilis CopZ: Cu(I)-binding and interactions with bacillithiol. Metallomics, 8 (7). pp. 709-719. ISSN 1756-591X

L

Lall, Namrita, Kumar, Vivek, Meyer, Debra, Gasa, Nomasomi, Hamilton, Chris, Matsabisa, Motlalepula and Oosthuizen, Carel (2016) In vitro and In vivo antimycobacterial, hepatoprotective and immunomodulatory activity of Euclea natalensis and its mode of action. Journal of Ethnopharmacology, 194. 740–748. ISSN 0378-8741

M

Managa, Muthumuni, Mack, John, Gonzalez Lucas, Daniel, Remiro Buenamanana, Sonia, Tshangana, Charmaine, Cammidge, Andrew ORCID: https://orcid.org/0000-0001-7912-4310 and Nyokong, Tebello (2016) Photophysical properties of tetraphenylporphyrinsubphthalocyanine conjugates. Journal of Porphyrins and Phthalocyanines, 20 (01n04). pp. 1-20. ISSN 1088-4246

Mills, Graham P., Hiatt-Gipson, Glyn D., Bew, Sean P. ORCID: https://orcid.org/0000-0002-9087-9463 and Reeves, Claire E. ORCID: https://orcid.org/0000-0003-4071-1926 (2016) Measurement of isoprene nitrates by GCMS. Atmospheric Measurement Techniques, 9 (9). pp. 4533-4545. ISSN 1867-1381

Myrtle, Jonathan D., Beekman, Andrew M. ORCID: https://orcid.org/0000-0002-3056-6406 and Barrow, Russell A. (2016) Ravynic acid, an antibiotic polyeneyne tetramic acid from Penicillium sp. elucidated through synthesis. Organic & Biomolecular Chemistry, 14 (35). pp. 8253-8260. ISSN 1477-0520

O

O'Neill, E. C., Saalbach, G. and Field, R. A. ORCID: https://orcid.org/0000-0001-8574-0275 (2016) Gene Discovery for Synthetic Biology:Exploring the Novel Natural Product Biosynthetic Capacity of Eukaryotic Microalgae. In: Methods in Enzymology. Methods in Enzymology . Academic Press Inc., pp. 99-120.

P

Prior, Christopher, Webster, Lee R., Ibrahim, Saad K., Wright, Joseph A. ORCID: https://orcid.org/0000-0001-9603-1001, Alghamdi, Ali F., Oganesyan, Vasily S. ORCID: https://orcid.org/0000-0002-8738-1146 and Pickett, Christopher J. (2016) EPR detection and characterisation of a paramagnetic Mo(III) dihydride intermediate involved in electrocatalytic hydrogen evolution. Dalton Transactions, 45 (6). pp. 2399-2403. ISSN 1477-9226

S

Schofield, Claire L., Marin, Maria J. ORCID: https://orcid.org/0000-0001-8021-5498, Rejzek, Martin, Crocker, Paul Richard, Field, Robert A. ORCID: https://orcid.org/0000-0001-8574-0275 and Russell, David A. (2016) Detection of mSiglec-E, in solution and expressed on the surface of Chinese hamster ovary cells, using sialic acid functionalised gold nanoparticles. The Analyst, 141 (20). pp. 5799-5809. ISSN 0003-2654

Sharma, Sunil V, Van Laer, Koen, Messens, Joris and Hamilton, Chris James (2016) Thiol redox and pKa properties of mycothiol, the predomiant low molecular weight thiol cofactor in the Actinomycetes. ChemBioChem, 17 (18). 1689–1692. ISSN 1439-4227

Stegmayr, John, Lepur, Adriana, Kahl-Knutson, Barbro, Aguilar-Moncayo, Matilde, Klyosov, Anatole A., Field, Robert A. ORCID: https://orcid.org/0000-0001-8574-0275, Oredsson, Stina, Nilsson, Ulf J. and Leffler, Hakon (2016) Low or no inhibitory potency of the canonical galectin carbohydrate-binding site by pectins and galactomannans. Journal of Biological Chemistry, 291 (25). pp. 13318-13334. ISSN 0021-9258

W

Wright, Joseph A. ORCID: https://orcid.org/0000-0001-9603-1001, Peck, Jamie N. T., Cottrell, Stephen P., Jablonskyte, Ausra, Oganesyan, Vasily S. ORCID: https://orcid.org/0000-0002-8738-1146, Pickett, Christopher J. and Jayasooriya, Upali A. (2016) Muonium chemistry at diiron subsite analogues of [FeFe]-hydrogenase. Angewandte Chemie-International Edition, 55 (47). 14580–14583. ISSN 1433-7851

Wright, Mark and Wright, Joseph ORCID: https://orcid.org/0000-0001-9603-1001 (2016) PhotoCORMs: CO release moves into the visible. Dalton Transactions, 45 (16). pp. 6801-6811. ISSN 1477-9226

Z

Zamoner, Luís Otávio B., Aragão-Leoneti, Valquíria, Mantoani, Susimaire P., Rugen, Michael D., Nepogodiev, Sergey A., Field, Robert A. ORCID: https://orcid.org/0000-0001-8574-0275 and Carvalho, Ivone (2016) CuAAC click chemistry with N-propargyl 1,5-dideoxy-1,5-imino-D-gulitol and N-propargyl 1,6-dideoxy-1,6-imino-D-mannitol provides access to triazole-linked piperidine and azepane pseudo-disaccharide iminosugars displaying glycosidase inhibitory properties. Carbohydrate Research, 429. pp. 29-37. ISSN 0008-6215