Items where Author is "Hutchings, Matthew"

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Number of items: 67.

Article

Vikeli, Eleni, Widdick, David, Batey, Sybil, Heine, Daniel, Holmes, Neil, Bibb, Mervyn, Martins, Dino, Pierce, Naomi, Hutchings, Matt and Wilkinson, Barrie (2020) In Situ Activation and Heterologous Production of a Cryptic Lantibiotic from an African Plant Ant-Derived Saccharopolyspora Species. Applied and Environmental Microbiology, 86 (3). pp. 1-14. ISSN 0099-2240

Hutchings, Matt, Truman, Andrew and Wilkinson, Barrie (2019) Antibiotics: past, present and future. Current Opinion in Microbiology, 51. pp. 72-80. ISSN 1369-5274

McLean, Thomas C., Lo, Rebecca, Tschowri, Natalia, Hoskisson, Paul, Al Bassam, Mahmoud, Hutchings, Matthew and Som, Nicolle (2019) Sensing and responding to diverse extracellular signals: An updated analysis of the sensor kinases and response regulators of Streptomyces spp. Microbiology, 165 (9). ISSN 1350-0872

Qin, Zhiwei, Devine, Rebecca, Hutchings, Matthew and Wilkinson, Barrie (2019) A role for antibiotic biosynthesis monooxygenase domain proteins in fidelity control during aromatic polyketide biosynthesis. Nature Communications, 10. ISSN 2041-1723

Tran, Ngat T., Huang, Xiaoluo, Hong, Hee-Jeon, Bush, Matthew, Chandra, Govind, Pinto, Daniela, Bibb, Maureen J., Hutchings, Matthew, Mascher, Thorsten and Buttner, Mark (2019) Defining the regulon of genes controlled by σE, a key regulator of the cell envelope stress response in Streptomyces coelicolor. Molecular Microbiology, 112 (2). pp. 461-481. ISSN 0950-382X

McLean, Thomas C, Wilkinson, Barrie, Hutchings, Matthew I and Devine, Rebecca (2019) Dissolution of the Disparate:Co-ordinate Regulation in Antibiotic Biosynthesis. Antibiotics, 8 (2). ISSN 2079-6382

Newitt, Jake, Prudence, Sam, Hutchings, Matthew and Worsley, Sarah (2019) Biocontrol of cereal crop diseases using streptomycetes. Pathogens, 8 (2). ISSN 2076-0817

Volbeda, Anne, Pellicer Martinez, Ma Teresa, Crack, Jason C, Amara, Patricia, Gigarel, Océane, Munnoch, John T, Hutchings, Matthew I, Darnault, Claudine, Le Brun, Nick E and Fontecilla-Camps, Juan C (2019) Crystal Structure of the Transcription Regulator RsrR Reveals a [2Fe-2S] Cluster Coordinated by Cys, Glu and His Residues. Journal of the American Chemical Society, 141 (6). 2367–2375. ISSN 0002-7863

Leftwich, Philip, Hutchings, Matthew and Chapman, Tracey (2018) Diet, Gut Microbes and Host Mate Choice:Understanding the significance of microbiome effects on host mate choice requires a case by case evaluation. BioEssays, 40 (12). ISSN 0265-9247

Heine, Daniel, Holmes, Neil A, Worsley, Sarah F, Santos, Ana Carolina A, Innocent, Tabitha M, Scherlach, Kirstin, Patrick, Elaine H, Yu, Douglas W, Murrell, J Colin, Viera, Paulo C, Boomsma, Jacobus J, Hertweck, Christian, Hutchings, Matthew I and Wilkinson, Barrie (2018) Chemical warfare between leafcutter ant symbionts and a co-evolved pathogen. Nature Communications, 9. ISSN 2041-1723

Leftwich, Philip T, Clarke, Naomi VE, Hutchings, Matthew I and Chapman, Tracey (2018) Reply to Obadia et al.: Effect of methyl paraben on host–microbiota interactions in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 115 (20). E4549-E4550. ISSN 1091-6490

Leftwich, Philip T, Clarke, Naomi VE, Hutchings, Matthew I and Chapman, Tracey (2018) Reply to Rosenberg et al: Diet, gut bacteria and assortative mating in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 115 (10). E2154-E2155.

Holmes, Neil A., Devine, Rebecca, Qin, Zhiwei, Seipke, Ryan F., Wilkinson, Barrie and Hutchings, Matthew I. (2018) Complete genome sequence of Streptomyces formicae KY5, the formicamycin producer. Journal of Biotechnology, 265. 116–118. ISSN 1873-4863

Leftwich, Philip, Clarke, Naomi, Hutchings, Matthew and Chapman, Tracey (2017) Gut microbiomes and reproductive isolation in Drosophila. Proceedings of the National Academy of Sciences of the United States of America, 114 (48). pp. 12767-12772. ISSN 1091-6490

Som, Nicolle F, Heine, Daniel, Holmes, Neil, Knowles, Felicity, Chandra, Govind, Seipke, Ryan F, Hoskisson, Paul A, Wilkinson, Barrie and Hutchings, Matthew I (2017) The MtrAB two-component system controls antibiotic production in Streptomyces coelicolor A3(2). Microbiology, 163 (10). pp. 1415-1419. ISSN 1350-0872

Som, Nicolle F., Heine, Daniel, Holmes, Neil A., Munnoch, John T., Chandra, Govind, Seipke, Ryan F., Hoskisson, Paul A., Wilkinson, Barrie and Hutchings, Matthew I. (2017) The conserved actinobacterial two-component system MtrAB coordinates chloramphenicol production with sporulation in Streptomyces venezuelae NRRL B-65442. Frontiers in Microbiology, 8. ISSN 1664-302X

Volbeda, Anne, Dodd, Erin L., Darnault, Claudine, Crack, Jason C., Renoux, Oriane, Hutchings, Matthew I., Le Brun, Nick E. and Fontecilla-Camps, Juan C. (2017) Crystal structures of the NO sensor NsrR reveal how its iron-sulfur cluster modulates DNA binding. Nature Communications, 8. ISSN 2041-1723

Qin, Zhiwei, Munnoch, John T, Devine, Rebecca, Holmes, Neil A, Seipke, Ryan F, Wilkinson, Karl A, Wilkinson, Barrie and Hutchings, Matthew I (2017) Formicamycins, antibacterial polyketides produced by Streptomyces formicae isolated from African Tetraponera plant-ants. Chemical Science, 8 (4). pp. 3218-3227. ISSN 2041-6520

van der Meij, Anne, Worsley, Sarah F., Hutchings, Matthew I. and van Wezel, Gilles P. (2017) Chemical ecology of antibiotic production by actinomycetes. FEMS Microbiology Reviews, 41 (3). pp. 392-416. ISSN 0168-6445

Holmes, Neil A., Innocent, Tabitha M., Heine, Daniel, Al-Bassam, Mahmoud, Worsley, Sarah F., Trottman, Felix, Patrick, Elaine H., Yu, Douglas W., Murrell, J. Colin, Schiott, Morten, Wilkinson, Barrie, Boomsma, Jacobus J. and Hutchings, Matthew I. (2016) Genome analysis of two Pseudonocardia phylotypes associated with Acromyrmex leafcutter ants reveals their biosynthetic potential. Frontiers in Microbiology, 7. ISSN 1664-302X

Serrano, Pauline N., Wang, Hongxin, Crack, Jason C., Prior, Christopher, Hutchings, Matthew I., Thomson, Andrew J., Kamali, Saeed, Yoda, Yoshitaka, Zhao, Jiyong, Hu, Michael Y., Alp, Ercan E., Oganesyan, Vasily S., Le Brun, Nick E. and Cramer, Stephen P. (2016) Nitrosylation of Nitric-Oxide-Sensing Regulatory Proteins Containing [4Fe-4S] Clusters Gives Rise to Multiple Iron-Nitrosyl Complexes. Angewandte Chemie International Edition, 55 (47). 14575–14579. ISSN 1433-7851

Munnoch, John T., Pellicer Martinez, Ma Teresa, Svistunenko, Dimitri A., Crack, Jason C., Le Brun, Nick E. and Hutchings, Matthew I. (2016) Characterization of a putative NsrR homologue in Streptomyces venezuelae reveals a new member of the Rrf2 superfamily. Scientific Reports, 6. ISSN 2045-2322

Munnoch, John T., Widdick, David A., Chandra, Govind, Sutcliffe, Iain C., Palmer, Tracy and Hutchings, Matthew I. (2016) Cosmid based mutagenesis causes genetic instability in Streptomyces coelicolor, as shown by targeting of the lipoprotein signal peptidase gene. Scientific Reports, 6. ISSN 2045-2322

Crack, Jason, Svistunenko, Dimitri A., Munnoch, John, Thomson, Andrew, Hutchings, Matthew and Le Brun, Nicolas (2016) Differentiated, promoter-specific response of [4Fe-4S] NsrR DNA-binding to reaction with nitric oxide. Journal of Biological Chemistry, 291. pp. 8663-8672. ISSN 0021-9258

Crack, Jason, Hutchings, Matthew, Thomson, Andrew and Le Brun, Nicolas (2016) Biochemical properties of Paracoccus denitrificans FnrP:Reactions with molecular oxygen and nitric oxide. JBIC Journal of Biological Inorganic Chemistry, 21 (1). pp. 71-82. ISSN 0949-8257

Crack, Jason, Munnoch, John Tyson, Dodd, Erin, Knowles, Felicity, Al-Bassam, Mahmoud, Kamali, Saeed, Holland, Ashley, Cramer, Stephen, Hamilton, Christopher, Johnson, Michael, Thomson, Andrew, Hutchings, Matthew and Le Brun, Nick (2015) NsrR from Streptomyces coelicolor is a nitric oxide-sensing [4Fe-4S] cluster protein with a specialized regulatory function. The Journal of Biological Chemistry, 290. pp. 12689-12704. ISSN 1083-351X

Gao, Hong, Grüschow, Sabine, Barke, Jörg, Seipke, Ryan F., Hill, Lionel M., Orivel, Jérôme, Yu, Douglas W., Hutchings, Matthew and Goss, Rebecca J. M. (2014) Filipins: the first antifungal “weed killers” identified from bacteria isolated from the trap-ant. RSC Advances, 4 (100). pp. 57267-57270. ISSN 2046-2069

Seipke, Ryan F., Patrick, Elaine and Hutchings, Matthew I. (2014) Regulation of antimycin biosynthesis by the orphan ECF RNA polymerase sigma factor σ (AntA.). PeerJ, 2. ISSN 2167-8359

Seipke, Ryan F and Hutchings, Matthew I (2013) The regulation and biosynthesis of antimycins. Beilstein Journal of Organic Chemistry, 9. pp. 2556-2563. ISSN 1860-5397

Seipke, Ryan F., Barke, Jörg, Heavens, Darren, Yu, Douglas W. and Hutchings, Matthew I. (2013) Analysis of the bacterial communities associated with two ant-plant symbioses. MicrobiologyOpen, 2 (2). pp. 276-283. ISSN 2045-8827

Clark, Laura C., Seipke, Ryan F., Prieto, Pilar, Willemse, Joost, van Wezel, Gilles P., Hutchings, Matthew I. and Hoskisson, Paul A. (2013) Mammalian cell entry genes in Streptomyces may provide clues to the evolution of bacterial virulence. Scientific Reports, 3. ISSN 2045-2322

Willemse, J., Ruban-osmialowska, B., Widdick, D., Celler, K., Hutchings, M. I., Van Wezel, G. P. and Palmer, T. (2012) Dynamic Localization of Tat Protein Transport Machinery Components in Streptomyces coelicolor. Journal of Bacteriology, 194 (22). pp. 6272-6281. ISSN 0021-9193

Sutcliffe, Iain C., Harrington, Dean J. and Hutchings, Matthew I. (2012) A phylum level analysis reveals lipoprotein biosynthesis to be a fundamental property of bacteria. Protein & Cell, 3 (3). pp. 163-170. ISSN 1674-800X

Crack, JC, Green, J, Hutchings, M, Thomson, AJ and Le Brun, NE (2012) Bacterial iron-sulfur regulatory proteins as biological sensor-switches. Antioxidants & Redox Signaling, 17. pp. 1215-1231. ISSN 1523-0864

Moore, Jane M., Bradshaw, Elizabeth, Seipke, Ryan F., Hutchings, Matthew I. and McArthur, Michael (2012) Use and discovery of chemical elicitors that stimulate biosynthetic gene clusters in Streptomyces bacteria. Methods in Enzymology, 517. pp. 367-385. ISSN 1557-7988

Seipke, RF, Barke, J, Ruiz-Gonzalez, MX, Orivel, J, Yu, DW and Hutchings, MI (2012) Fungus-growing Allomerus ants are associated with antibiotic-producing Actinobacteria. Antonie van Leeuwenhoek, 101. pp. 443-447.

Seipke, Ryan, Gruschow, Sabine, Goss, Rebecca and Hutchings, Matthew (2012) Isolating antifungals from fungus-growing ant symbionts using a genome-guided chemistry approach. Methods in Enzymology, 517. pp. 47-70. ISSN 1557-7988

Seipke, Ryan F., Barke, Jörg, Brearley, Charles, Hill, Lionel, Yu, Douglas W., Goss, Rebecca J. M. and Hutchings, Matthew I. (2011) A single Streptomyces symbiont makes multiple antifungals to support the fungus farming ant Acromyrmex octospinosus. PLoS One, 6 (8). ISSN 1932-6203

Seipke, RF, Crossman, L, Drou, N, Heavens, D, Bibb, MJ, Caccamo, M and Hutchings, MI (2011) Draft Genome Sequence of Streptomyces Strain S4, a Symbiont of the Leaf-Cutting Ant Acromyrmex octospinosus. Journal of Bacteriology, 193 (16). pp. 4270-4271. ISSN 0021-9193

Barke, J, Seipke, RF, Yu, DW and Hutchings, MI (2011) A mutualistic microbiome: How do fungus-growing ants select their antibiotic-producing bacteria? Communicative and Integrative Biology, 4. pp. 41-43. ISSN 1942-0889

Bellota-Antón, César, Munnoch, John, Robb, Kirsty, Adamczyk, Katrin, Candelaresi, Marco, Parker, Anthony W., Dixon, Ray, Hutchings, Matthew I., Hunt, Neil T. and Tucker, Nicholas P. (2011) Spectroscopic analysis of protein Fe-NO complexes. Biochemical Society Transactions, 39. pp. 1293-1298. ISSN 1470-8752

Seipke, Ryan F., Kaltenpoth, Martin and Hutchings, Matthew I. (2011) Streptomyces as symbionts: an emerging and widespread theme? FEMS Microbiology Reviews, 36. pp. 862-876. ISSN 1574-6976

Widdick, David A., Hicks, Matthew G., Thompson, Benjamin J., Tschumi, Andreas, Chandra, Govind, Sutcliffe, Iain C., Brülle, Julian K., Sander, Peter, Palmer, Tracy and Hutchings, Matthew I. (2011) Dissecting the complete lipoprotein biogenesis pathway in Streptomyces scabies. Molecular Microbiology, 80 (5). pp. 1395-1412. ISSN 1365-2958

Barke, Jörg, Seipke, Ryan F., Grüschow, Sabine, Heavens, Darren, Drou, Nizar, Bibb, Mervyn J., Goss, Rebecca J. M., Yu, Douglas and Hutchings, Matthew I. (2010) A mixed community of actinomycetes produce multiple antibiotics for the fungus farming ant Acromyrmex octospinosus. BMC Biology, 8. ISSN 1741-7007

Joshi, Madhumita V., Mann, Stefan G., Antelmann, Haike, Widdick, David A., Fyans, Joanna K., Chandra, Govind, Hutchings, Matthew I., Toth, Ian, Hecker, Michael, Loria, Rosemary and Palmer, Tracy (2010) The twin arginine protein transport pathway exports multiple virulence proteins in the plant pathogen Streptomyces scabies. Molecular Microbiology, 77 (1). pp. 252-271. ISSN 0950-382X

Tucker, NP, Le Brun, NE, Dixon, R and Hutchings, MI (2010) There's NO stopping NsrR, a global regulator of the bacterial NO stress response. Trends in Microbiology, 18 (4). pp. 149-156. ISSN 1878-4380

Thompson, Benjamin J., Widdick, David A., Hicks, Matthew G., Chandra, Govind, Sutcliffe, Iain C., Palmer, Tracy and Hutchings, Matthew I. (2010) Investigating lipoprotein biogenesis and function in the model Gram-positive bacterium Streptomyces coelicolor. Molecular Microbiology, 77 (4). pp. 943-957. ISSN 0950-382X

Hutchings, MI, Palmer, T, Harrington, DJ and Sutcliffe, IC (2009) Lipoprotein biogenesis in Gram-positive bacteria: knowing when to hold 'em, knowing when to fold 'em. Trends in Microbiology, 17 (1). pp. 13-21. ISSN 0966-842X

Tucker, Nicholas P., Hicks, Matthew G., Clarke, Thomas A., Crack, Jason C., Chandra, Govind, Le Brun, Nick E., Dixon, Ray and Hutchings, Matthew I. (2008) The transcriptional repressor protein NsrR senses nitric oxide directly via a [2Fe-2S] cluster. PLoS One, 3 (11). ISSN 1932-6203

Jordan, Sina, Hutchings, Matthew I. and Mascher, Thorsten (2008) Cell envelope stress response in Gram-positive bacteria. FEMS Microbiology Reviews, 32 (1). pp. 107-146. ISSN 1574-6976

Gaskell, Alisa A., Crack, Jason C., Kelemen, Gabriella K., Hutchings, Matthew I. and Le Brun, Nick E. (2007) RsmA, an anti-sigma factor from Streptomyces coelicolor, modulates its activity through a [2Fe-2s] cluster cofactor. Journal of Biological Chemistry, 282 (43). pp. 31812-31820. ISSN 0021-9258

Hutchings, M.I. (2007) Unusual Signal Transduction Pathways in the Actinobacteria. Advances in Applied Microbiology, 61. pp. 1-26.

Sutcliffe, I.C. and Hutchings, M.I. (2007) Putative lipoproteins identified by bioinformatic genome analysis of Leifsonia xyli spp xyli, the causative agent of sugarcane ratoon stunting disease. Molecular Plant Pathology, 8. pp. 121-128. ISSN 1364-3703

Hoskisson, Paul A. and Hutchings, Matthew I. (2006) MtrAB-LpqB: a conserved threecomponent system in actinobacteria? Trends in Microbiology, 14 (10). pp. 444-449. ISSN 1878-4380

Hutchings, M.I., Hong, H.J. and Buttner, M.J. (2006) The vancomycin resistance VanRS two-component signal transduction system of Streptomyces coelicolor. Molecular Microbiology, 59 (3). pp. 923-935. ISSN 0950-382X

Hutchings, Matthew I., Hong, Hee-Jeon, Leibovitz, Emmanuelle, Sutcliffe, Iain C. and Buttner, Mark J. (2006) The sigma(E) cell envelope stress response of Streptomyces coelicolor is influenced by a novel lipoprotein, CseA. Journal of Bacteriology, 188 (20). pp. 7222-7229.

Hutchings, M., Hong, H.-J., Hill, L. M. and Buttner, M. J. (2005) The role of the novel Fem protein VanK in vancomycin resistance in Streptomyces coelicolor. Journal of Biological Chemistry, 280 (13). pp. 13055-13061. ISSN 0021-9258

Hong, Hee-Jeon, Hutchings, Matthew I., Neu, John M., Wright, Gerard D., Paget, Mark S. B. and Buttner, Mark J. (2004) Characterisation of an inducible vancomycin resistance system in Streptomyces coelicolor reveals a novel gene (vanK) required for drug resistance. Molecular Microbiology, 52 (4). pp. 1107-1121. ISSN 1365-2958

Hutchings, Matthew I., Hoskisson, Paul A., Chandra, Govind and Buttner, Mark J. (2004) Sensing and responding to diverse extracellular signals? Analysis of the sensor kinases and response regulators of Streptomyces coelicolor A3(2). Microbiology, 150 (9). pp. 2795-2806. ISSN 1465-2080

Zhou, Xiaoying, Hovell, Christopher J., Pawley, Susannah, Hutchings, Matthew I., Arthur, Michael J. P., Iredale, John P. and Benyon, R. Christopher (2004) Expression of matrix metalloproteinase-2 and -14 persists during early resolution of experimental liver fibrosis and might contribute to fibrolysis. Liver International, 24 (5). pp. 492-501. ISSN 1478-3223

Hutchings, Matthew I., Crack, Jason C., Shearer, Neil, Thompson, Benjamin J., Thomson, Andrew J. and Spiro, Stephen (2002) Transcription factor FnrP from Paracoccus denitrificans contains an iron-sulfur cluster and is activated by anoxia: Identification of essential cysteine residues. Journal of Bacteriology, 184 (2). pp. 503-508. ISSN 0021-9193

Hutchings, Matthew I., Mandhana, Neeraj and Spiro, Stephen (2002) The NorR protein of Escherichia coli activates expression of the flavorubredoxin gene norV in response to reactive nitrogen species. Journal of Bacteriology, 184 (16). pp. 4640-4643. ISSN 0021-9193

Hutchings, Matthew I. and Drabble, William T. (2000) Regulation of the divergentguaBAandxseApromoters of Escherichia coliby the cyclic AMP receptor protein. FEMS Microbiology Letters, 187 (2). pp. 115-122. ISSN 1574-6968

Hutchings, MI and Spiro, S (2000) The nitric oxide regulated nor promoter of Paracoccus denitrificans. Microbiology, 146. pp. 2635-2641. ISSN 1465-2080

Hutchings, Matthew I., Shearer, Neil, Wastell, Sarah, van Spanning, Rob J. M. and Spiro, Stephen (2000) Heterologous NNR-Mediated Nitric Oxide Signaling in Escherichia coli. Journal of Bacteriology, 182 (22). pp. 6434-6439. ISSN 0021-9193

Book Section

Palmer, T and Hutchings, MI (2011) Protein secretion in Streptomyces. In: Streptomyces Molecular Biology and Biotechnology. Academic Press, Caister.

Hong, H-J., Hutchings, M.I. and Buttner, M.J. (2007) Vancomycin Resistance VanRS two-component systems. In: Bacterial Signal Transduction: Networks and Drug Targets. Landes Bioscience.

This list was generated on Wed Apr 8 16:19:12 2020 BST.