Complete genome sequence of Streptomyces formicae KY5, the formicamycin producer

Holmes, Neil A., Devine, Rebecca, Qin, Zhiwei, Seipke, Ryan F., Wilkinson, Barrie and Hutchings, Matthew I. (2018) Complete genome sequence of Streptomyces formicae KY5, the formicamycin producer. Journal of Biotechnology, 265. 116–118. ISSN 1873-4863

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Abstract

Here we report the complete genome of the new species Streptomyces formicae KY5 isolated from Tetraponera fungus growing ants. S. formicae was sequenced using the PacBio and 454 platforms to generate a single linear chromosome with terminal inverted repeats. Illumina MiSeq sequencing was used to correct base changes resulting from the high error rate associated with PacBio. The genome is 9.6 Mbps, has a GC content of 71.38% and contains 8162 protein coding sequences. Predictive analysis shows this strain encodes at least 45 gene clusters for the biosynthesis of secondary metabolites, including a type 2 polyketide synthase encoding cluster for the antibacterial formicamycins. Streptomyces formicae KY5 is a new, taxonomically distinct Streptomyces species and this complete genome sequence provides an important marker in the genus of Streptomyces.

Item Type: Article
Uncontrolled Keywords: streptomyces formicae ky5,tetraponera penzigi,genome sequence,antibiotics,secondary metabolites
Faculty \ School: Faculty of Science > School of Biological Sciences
Faculty of Medicine and Health Sciences > Norwich Medical School
Faculty of Science > School of Chemistry
Depositing User: Pure Connector
Date Deposited: 29 Nov 2017 06:07
Last Modified: 22 Jul 2020 01:53
URI: https://ueaeprints.uea.ac.uk/id/eprint/65596
DOI: 10.1016/j.jbiotec.2017.11.011

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