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ToolsHolmes, Neil A., Devine, Rebecca, Qin, Zhiwei, Seipke, Ryan F., Wilkinson, Barrie and Hutchings, Matthew I. (2018) Complete genome sequence of Streptomyces formicae KY5, the formicamycin producer. Journal of Biotechnology, 265. 116–118. ISSN 1873-4863
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Abstract
Here we report the complete genome of the new species Streptomyces formicae KY5 isolated from Tetraponera fungus growing ants. S. formicae was sequenced using the PacBio and 454 platforms to generate a single linear chromosome with terminal inverted repeats. Illumina MiSeq sequencing was used to correct base changes resulting from the high error rate associated with PacBio. The genome is 9.6 Mbps, has a GC content of 71.38% and contains 8162 protein coding sequences. Predictive analysis shows this strain encodes at least 45 gene clusters for the biosynthesis of secondary metabolites, including a type 2 polyketide synthase encoding cluster for the antibacterial formicamycins. Streptomyces formicae KY5 is a new, taxonomically distinct Streptomyces species and this complete genome sequence provides an important marker in the genus of Streptomyces.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | streptomyces formicae ky5,tetraponera penzigi,genome sequence,antibiotics,secondary metabolites |
| Faculty \ School: | Faculty of Science > School of Biological Sciences Faculty of Medicine and Health Sciences > Norwich Medical School Faculty of Science > School of Chemistry (former - to 2024) |
| UEA Research Groups: | Faculty of Science > Research Groups > Molecular Microbiology Faculty of Science > Research Groups > Organisms and the Environment |
| Depositing User: | Pure Connector |
| Date Deposited: | 29 Nov 2017 06:07 |
| Last Modified: | 18 Oct 2024 23:46 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/65596 |
| DOI: | 10.1016/j.jbiotec.2017.11.011 |
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