Items where Author is "Hutchings, Matthew"

Gray, Elizabeth, Stewart, Melissa Y. Y., Hanwell, Libby, Crack, Jason C., Devine, Rebecca, Stevenson, Clare E. M., Volbeda, Anne, Johnston, Andrew W. B., Fontecilla-Camps, Juan C., Hutchings, Matthew I., Todd, Jonathan D. and Le Brun, Nick E. ORCID: https://orcid.org/0000-0001-9780-4061 (2023) Stabilisation of the RirA [4Fe–4S] cluster results in loss of iron-sensing function. Chemical Science, 14 (36). pp. 9744-9758. ISSN 2041-6520

Worsley, Sarah F., Davies, Charli S., Mannarelli, Maria-Elena, Hutchings, Matthew I., Komdeur, Jan, Burke, Terry, Dugdale, Hannah L. and Richardson, David S. ORCID: https://orcid.org/0000-0001-7226-9074 (2021) Gut microbiome composition, not alpha diversity, is associated with survival in a natural vertebrate population. Animal Microbiome, 3 (1). ISSN 2524-4671

Prudence, Samuel M. M., Newitt, Jake T., Worsley, Sarah F., Macey, Michael C., Murrell, J. Colin, Lehtovirta-Morley, Laura E. and Hutchings, Matthew I. (2021) Soil, senescence and exudate utilisation: characterisation of the Paragon var. spring bread wheat root microbiome. Environmental Microbiome, 16 (1). ISSN 2524-6372

Darrington, Michael, Leftwich, Philip T. ORCID: https://orcid.org/0000-0001-9500-6592, Holmes, Neil A., Friend, Lucy A., Clarke, Naomi V. E., Worsley, Sarah F., Margaritopoulos, John T., Hogenhout, Saskia Adriane, Hutchings, Matthew I. and Chapman, Tracey (2021) Characterisation of the symbionts in the Mediterranean fruitfly gut. UNSPECIFIED.

Qin, Zhiwei, Devine, Rebecca, Booth, Thomas, Farrar, Elliot, Grayson, Matthew, Hutchings, Matt and Wilkinson, Barrie (2020) Formicamycin biosynthesis involves a unique reductive ring contraction. Chemical Science, 11 (31). pp. 8125-8131. ISSN 2041-6520

McLean, Thomas C., Lo, Rebecca, Tschowri, Natalia, Hoskisson, Paul, Al Bassam, Mahmoud, Hutchings, Matthew and Som, Nicolle (2019) Sensing and responding to diverse extracellular signals: An updated analysis of the sensor kinases and response regulators of Streptomyces spp. Microbiology, 165 (9). pp. 929-952. ISSN 1350-0872

Tran, Ngat T., Huang, Xiaoluo, Hong, Hee-Jeon, Bush, Matthew, Chandra, Govind, Pinto, Daniela, Bibb, Maureen J., Hutchings, Matthew, Mascher, Thorsten and Buttner, Mark (2019) Defining the regulon of genes controlled by σE, a key regulator of the cell envelope stress response in Streptomyces coelicolor. Molecular Microbiology, 112 (2). pp. 461-481. ISSN 0950-382X

Leftwich, Philip T ORCID: https://orcid.org/0000-0001-9500-6592, Clarke, Naomi VE, Hutchings, Matthew I and Chapman, Tracey (2018) Reply to Obadia et al.: Effect of methyl paraben on host–microbiota interactions in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 115 (20). E4549-E4550. ISSN 1091-6490

Leftwich, Philip T ORCID: https://orcid.org/0000-0001-9500-6592, Clarke, Naomi VE, Hutchings, Matthew I and Chapman, Tracey (2018) Reply to Rosenberg et al: Diet, gut bacteria and assortative mating in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 115 (10). E2154-E2155. ISSN 1091-6490

Leftwich, Philip ORCID: https://orcid.org/0000-0001-9500-6592, Clarke, Naomi, Hutchings, Matthew and Chapman, Tracey (2017) Gut microbiomes and reproductive isolation in Drosophila. Proceedings of the National Academy of Sciences of the United States of America, 114 (48). pp. 12767-12772. ISSN 1091-6490

Som, Nicolle F., Heine, Daniel, Holmes, Neil A., Munnoch, John T., Chandra, Govind, Seipke, Ryan F., Hoskisson, Paul A., Wilkinson, Barrie and Hutchings, Matthew I. (2017) The conserved actinobacterial two-component system MtrAB coordinates chloramphenicol production with sporulation in Streptomyces venezuelae NRRL B-65442. Frontiers in Microbiology, 8. ISSN 1664-302X

Qin, Zhiwei, Munnoch, John T, Devine, Rebecca, Holmes, Neil A, Seipke, Ryan F, Wilkinson, Karl A, Wilkinson, Barrie and Hutchings, Matthew I (2017) Formicamycins, antibacterial polyketides produced by Streptomyces formicae isolated from African Tetraponera plant-ants. Chemical Science, 8 (4). pp. 3218-3227. ISSN 2041-6520

Holmes, Neil A., Innocent, Tabitha M., Heine, Daniel, Al-Bassam, Mahmoud, Worsley, Sarah F., Trottman, Felix, Patrick, Elaine H., Yu, Douglas W., Murrell, J. Colin, Schiott, Morten, Wilkinson, Barrie, Boomsma, Jacobus J. and Hutchings, Matthew I. (2016) Genome analysis of two Pseudonocardia phylotypes associated with Acromyrmex leafcutter ants reveals their biosynthetic potential. Frontiers in Microbiology, 7. ISSN 1664-302X

Munnoch, John T., Pellicer Martinez, Ma Teresa, Svistunenko, Dimitri A., Crack, Jason C., Le Brun, Nick E. ORCID: https://orcid.org/0000-0001-9780-4061 and Hutchings, Matthew I. (2016) Characterization of a putative NsrR homologue in Streptomyces venezuelae reveals a new member of the Rrf2 superfamily. Scientific Reports, 6. ISSN 2045-2322

Munnoch, John T., Widdick, David A., Chandra, Govind, Sutcliffe, Iain C., Palmer, Tracy and Hutchings, Matthew I. (2016) Cosmid based mutagenesis causes genetic instability in Streptomyces coelicolor, as shown by targeting of the lipoprotein signal peptidase gene. Scientific Reports, 6. ISSN 2045-2322

Crack, Jason, Munnoch, John Tyson, Dodd, Erin, Knowles, Felicity, Al-Bassam, Mahmoud, Kamali, Saeed, Holland, Ashley, Cramer, Stephen, Hamilton, Christopher, Johnson, Michael, Thomson, Andrew, Hutchings, Matthew and Le Brun, Nick ORCID: https://orcid.org/0000-0001-9780-4061 (2015) NsrR from Streptomyces coelicolor is a nitric oxide-sensing [4Fe-4S] cluster protein with a specialized regulatory function. The Journal of Biological Chemistry, 290. pp. 12689-12704. ISSN 1083-351X

Gao, Hong, Grüschow, Sabine, Barke, Jörg, Seipke, Ryan F., Hill, Lionel M., Orivel, Jérôme, Yu, Douglas W., Hutchings, Matthew and Goss, Rebecca J. M. (2014) Filipins: the first antifungal “weed killers” identified from bacteria isolated from the trap-ant. RSC Advances, 4 (100). pp. 57267-57270. ISSN 2046-2069

Seipke, Ryan F., Patrick, Elaine and Hutchings, Matthew I. (2014) Regulation of antimycin biosynthesis by the orphan ECF RNA polymerase sigma factor σ (AntA.). PeerJ, 2. ISSN 2167-8359

Seipke, Ryan F and Hutchings, Matthew I (2013) The regulation and biosynthesis of antimycins. Beilstein Journal of Organic Chemistry, 9. pp. 2556-2563. ISSN 1860-5397

Seipke, Ryan F., Barke, Jörg, Heavens, Darren, Yu, Douglas W. and Hutchings, Matthew I. (2013) Analysis of the bacterial communities associated with two ant-plant symbioses. MicrobiologyOpen, 2 (2). pp. 276-283. ISSN 2045-8827

Willemse, Joost, Ruban-Osmialowska, Beata, Widdick, David, Celler, Katherine, Hutchings, Matthew I., van Wezel, Gilles P. and Palmer, Tracy (2012) Dynamic localization of Tat protein transport machinery components in Streptomyces coelicolor. Journal of Bacteriology, 194 (22). pp. 6272-6281. ISSN 0021-9193

Crack, Jason C., Green, Jeffrey, Hutchings, Matthew I., Thomson, Andrew J. and Le Brun, Nick E. ORCID: https://orcid.org/0000-0001-9780-4061 (2012) Bacterial iron-sulfur regulatory proteins as biological sensor-switches. Antioxidants & Redox Signaling, 17. pp. 1215-1231. ISSN 1523-0864

Sutcliffe, Iain C., Harrington, Dean J. and Hutchings, Matthew I. (2012) A phylum level analysis reveals lipoprotein biosynthesis to be a fundamental property of bacteria. Protein & Cell, 3 (3). pp. 163-170. ISSN 1674-800X

Moore, Jane M., Bradshaw, Elizabeth, Seipke, Ryan F., Hutchings, Matthew I. and McArthur, Michael (2012) Use and discovery of chemical elicitors that stimulate biosynthetic gene clusters in Streptomyces bacteria. Methods in Enzymology, 517. pp. 367-385. ISSN 1557-7988

Seipke, Ryan, Gruschow, Sabine, Goss, Rebecca and Hutchings, Matthew (2012) Isolating antifungals from fungus-growing ant symbionts using a genome-guided chemistry approach. Methods in Enzymology, 517. pp. 47-70. ISSN 1557-7988

Seipke, Ryan F., Barke, Jörg, Ruiz-Gonzalez, Mario X., Orivel, Jérôme, Yu, Douglas W. and Hutchings, Matthew I. (2012) Fungus-growing Allomerus ants are associated with antibiotic-producing Actinobacteria. Antonie van Leeuwenhoek, 101. pp. 443-447. ISSN 1572-9699

Seipke, Ryan F., Barke, Jörg, Brearley, Charles ORCID: https://orcid.org/0000-0001-6179-9109, Hill, Lionel, Yu, Douglas W., Goss, Rebecca J. M. and Hutchings, Matthew I. (2011) A single Streptomyces symbiont makes multiple antifungals to support the fungus farming ant Acromyrmex octospinosus. PLoS One, 6 (8). ISSN 1932-6203

Seipke, Ryan F., Crossman, Lisa, Drou, Nizar, Heavens, Darren, Bibb, Mervyn J., Caccamo, Mario and Hutchings, Matthew I. (2011) Draft genome sequence of Streptomyces strain S4, a symbiont of the leaf-cutting ant Acromyrmex octospinosus. Journal of Bacteriology, 193 (16). pp. 4270-4271. ISSN 0021-9193

Barke, J, Seipke, RF, Yu, DW and Hutchings, MI (2011) A mutualistic microbiome: How do fungus-growing ants select their antibiotic-producing bacteria? Communicative and Integrative Biology, 4. pp. 41-43. ISSN 1942-0889

Bellota-Antón, César, Munnoch, John, Robb, Kirsty, Adamczyk, Katrin, Candelaresi, Marco, Parker, Anthony W., Dixon, Ray, Hutchings, Matthew I., Hunt, Neil T. and Tucker, Nicholas P. (2011) Spectroscopic analysis of protein Fe-NO complexes. Biochemical Society Transactions, 39 (5). pp. 1293-1298. ISSN 1470-8752

Palmer, T. and Hutchings, M. I. (2011) Protein secretion in Streptomyces. In: Streptomyces Molecular Biology and Biotechnology. Academic Press, Caister.

Seipke, Ryan F., Kaltenpoth, Martin and Hutchings, Matthew I. (2011) Streptomyces as symbionts: an emerging and widespread theme? FEMS Microbiology Reviews, 36. pp. 862-876. ISSN 1574-6976

Widdick, David A., Hicks, Matthew G., Thompson, Benjamin J., Tschumi, Andreas, Chandra, Govind, Sutcliffe, Iain C., Brülle, Julian K., Sander, Peter, Palmer, Tracy and Hutchings, Matthew I. (2011) Dissecting the complete lipoprotein biogenesis pathway in Streptomyces scabies. Molecular Microbiology, 80 (5). pp. 1395-1412. ISSN 1365-2958

Joshi, Madhumita V., Mann, Stefan G., Antelmann, Haike, Widdick, David A., Fyans, Joanna K., Chandra, Govind, Hutchings, Matthew I., Toth, Ian, Hecker, Michael, Loria, Rosemary and Palmer, Tracy (2010) The twin arginine protein transport pathway exports multiple virulence proteins in the plant pathogen Streptomyces scabies. Molecular Microbiology, 77 (1). pp. 252-271. ISSN 0950-382X

Tucker, Nicholas P., Le Brun, Nick E. ORCID: https://orcid.org/0000-0001-9780-4061, Dixon, Ray and Hutchings, Matthew I. (2010) There's NO stopping NsrR, a global regulator of the bacterial NO stress response. Trends in Microbiology, 18 (4). pp. 149-156. ISSN 1878-4380

Thompson, Benjamin J., Widdick, David A., Hicks, Matthew G., Chandra, Govind, Sutcliffe, Iain C., Palmer, Tracy and Hutchings, Matthew I. (2010) Investigating lipoprotein biogenesis and function in the model Gram-positive bacterium Streptomyces coelicolor. Molecular Microbiology, 77 (4). pp. 943-957. ISSN 0950-382X

Hutchings, Matthew I., Palmer, Tracy, Harrington, Dean J. and Sutcliffe, Iain C. (2009) Lipoprotein biogenesis in Gram-positive bacteria: knowing when to hold 'em, knowing when to fold 'em. Trends in Microbiology, 17 (1). pp. 13-21. ISSN 0966-842X

Jordan, Sina, Hutchings, Matthew I. and Mascher, Thorsten (2008) Cell envelope stress response in Gram-positive bacteria. FEMS Microbiology Reviews, 32 (1). pp. 107-146. ISSN 1574-6976

Gaskell, Alisa A., Crack, Jason C., Kelemen, Gabriella K., Hutchings, Matthew I. and Le Brun, Nick E. ORCID: https://orcid.org/0000-0001-9780-4061 (2007) RsmA, an anti-sigma factor from Streptomyces coelicolor, modulates its activity through a [2Fe-2s] cluster cofactor. Journal of Biological Chemistry, 282 (43). pp. 31812-31820. ISSN 0021-9258

Hong, H-J., Hutchings, M.I. and Buttner, M.J. (2007) Vancomycin Resistance VanRS two-component systems. In: Bacterial Signal Transduction: Networks and Drug Targets. Landes Bioscience.

Hutchings, Matthew I. (2007) Unusual two-component signal transduction pathways in the actinobacteria. Advances in Applied Microbiology, 61. pp. 1-26.

Sutcliffe, Iain C. and Hutchings, Matthew I. (2007) Putative lipoproteins identified by bioinformatic genome analysis of Leifsonia xyli spp xyli, the causative agent of sugarcane ratoon stunting disease. Molecular Plant Pathology, 8 (1). pp. 121-128. ISSN 1364-3703

Hoskisson, Paul A. and Hutchings, Matthew I. (2006) MtrAB-LpqB: a conserved threecomponent system in actinobacteria? Trends in Microbiology, 14 (10). pp. 444-449. ISSN 1878-4380

Hutchings, Matthew I., Hong, Hee-Jeon and Buttner, Mark J. (2006) The vancomycin resistance VanRS two-component signal transduction system of Streptomyces coelicolor. Molecular Microbiology, 59 (3). pp. 923-935. ISSN 0950-382X

Hutchings, Matthew I., Hong, Hee-Jeon, Leibovitz, Emmanuelle, Sutcliffe, Iain C. and Buttner, Mark J. (2006) The sigma(E) cell envelope stress response of Streptomyces coelicolor is influenced by a novel lipoprotein, CseA. Journal of Bacteriology, 188 (20). pp. 7222-7229. ISSN 1098-5530

Hong, Hee-Jeon, Hutchings, Matthew I., Hill, Lionel M. and Buttner, Mark J. (2005) The role of the novel Fem protein VanK in vancomycin resistance in Streptomyces coelicolor. Journal of Biological Chemistry, 280 (13). pp. 13055-13061. ISSN 0021-9258

Hong, Hee-Jeon, Hutchings, Matthew I., Neu, John M., Wright, Gerard D., Paget, Mark S. B. and Buttner, Mark J. (2004) Characterisation of an inducible vancomycin resistance system in Streptomyces coelicolor reveals a novel gene (vanK) required for drug resistance. Molecular Microbiology, 52 (4). pp. 1107-1121. ISSN 1365-2958

Hutchings, Matthew I., Hoskisson, Paul A., Chandra, Govind and Buttner, Mark J. (2004) Sensing and responding to diverse extracellular signals? Analysis of the sensor kinases and response regulators of Streptomyces coelicolor A3(2). Microbiology, 150 (9). pp. 2795-2806. ISSN 1465-2080

Zhou, Xiaoying, Hovell, Christopher J., Pawley, Susannah, Hutchings, Matthew I., Arthur, Michael J. P., Iredale, John P. and Benyon, R. Christopher (2004) Expression of matrix metalloproteinase-2 and -14 persists during early resolution of experimental liver fibrosis and might contribute to fibrolysis. Liver International, 24 (5). pp. 492-501. ISSN 1478-3223

Hutchings, Matthew I., Crack, Jason C., Shearer, Neil, Thompson, Benjamin J., Thomson, Andrew J. and Spiro, Stephen (2002) Transcription factor FnrP from Paracoccus denitrificans contains an iron-sulfur cluster and is activated by anoxia: Identification of essential cysteine residues. Journal of Bacteriology, 184 (2). pp. 503-508. ISSN 0021-9193

Hutchings, Matthew I., Mandhana, Neeraj and Spiro, Stephen (2002) The NorR protein of Escherichia coli activates expression of the flavorubredoxin gene norV in response to reactive nitrogen species. Journal of Bacteriology, 184 (16). pp. 4640-4643. ISSN 0021-9193

Hutchings, Matthew I. and Drabble, William T. (2000) Regulation of the divergentguaBAandxseApromoters of Escherichia coliby the cyclic AMP receptor protein. FEMS Microbiology Letters, 187 (2). pp. 115-122. ISSN 1574-6968

Hutchings, Matthew I., Shearer, Neil, Wastell, Sarah, van Spanning, Rob J. M. and Spiro, Stephen (2000) Heterologous NNR-mediated nitric oxide signaling in Escherichia coli. Journal of Bacteriology, 182 (22). pp. 6434-6439. ISSN 0021-9193

Hutchings, Matthew I. and Spiro, Stephen (2000) The nitric oxide regulated nor promoter of Paracoccus denitrificans. Microbiology, 146 (10). pp. 2635-2641. ISSN 1465-2080