Items where Research Group is "Cancer Studies

A

Attard, G., Clark, J., Ambroisine, L., Fisher, G., Kovacs, G., Flohr, P., Berney, D., Foster, C. S., Fletcher, A., Gerald, W. L., Moller, H., Reuter, V., de Bono, J. S., Scardino, P., Cuzick, J. and Cooper, C. S. ORCID: https://orcid.org/0000-0003-2013-8042 and Transatlantic Prostate Group (2008) Duplication of the fusion of TMPRSS2 to ERG sequences identifies fatal human prostate cancer. Oncogene, 27 (3). pp. 253-263. ISSN 1476-5594

Attard, G., Clark, J., Ambroisine, L., Mills, I. G., Fisher, G., Flohr, P., Reid, A., Edwards, S., Kovacs, G., Berney, D., Foster, C., Massie, C. E., Fletcher, A., De Bono, J. S., Scardino, P., Cuzick, J. and Cooper, C. S. ORCID: https://orcid.org/0000-0003-2013-8042 (2008) Heterogeneity and clinical significance of ETV1 translocations in human prostate cancer. British Journal of Cancer, 99 (2). pp. 314-320. ISSN 0007-0920

Attard, G., Jameson, C., Moreira, J., Flohr, P., Parker, C., Dearnaley, D., Cooper, C. S. ORCID: https://orcid.org/0000-0003-2013-8042 and De Bono, J. S. (2008) Hormone-sensitive prostate cancer:A case of ETS gene fusion heterogeneity. Journal of Clinical Pathology, 62 (4). pp. 373-376. ISSN 0021-9746

Attard, Gerhardt, Reid, Alison H M, Yap, Timothy A, Raynaud, Florence, Dowsett, Mitch, Settatree, Sarah, Barrett, Mary, Parker, Christopher, Martins, Vanessa, Folkerd, Elizabeth, Clark, Jeremy, Cooper, Colin S ORCID: https://orcid.org/0000-0003-2013-8042, Kaye, Stan B, Dearnaley, David, Lee, Gloria and de Bono, Johann S (2008) Phase I clinical trial of a selective inhibitor of CYP17, abiraterone acetate, confirms that castration-resistant prostate cancer commonly remains hormone driven. Journal of Clinical Oncology, 26 (28). pp. 4563-71. ISSN 1527-7755

B

Brewer, Daniel ORCID: https://orcid.org/0000-0003-4753-9794, Barenco, Martino, Callard, Robin, Hubank, Michael and Stark, Jaroslav (2008) Fitting ordinary differential equations to short time course data. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 366 (1865). pp. 519-544. ISSN 1364-503X

C

Clark, Ian M., Swingler, Tracey E., Sampieri, Clara L. and Edwards, Dylan R. ORCID: https://orcid.org/0000-0002-3292-2064 (2008) The regulation of matrix metalloproteinases and their inhibitors. International Journal of Biochemistry & Cell Biology, 40 (6-7). pp. 1362-1378. ISSN 1878-5875

Clark, J., Attard, G., Jhavar, S., Flohr, P., Reid, A., De-Bono, J., Eeles, R., Scardino, P., Cuzick, J., Fisher, G., Parker, M. D., Foster, C. S., Berney, D., Kovacs, G. and Cooper, C. S. ORCID: https://orcid.org/0000-0003-2013-8042 (2008) Complex patterns of ETS gene alteration arise during cancer development in the human prostate. Oncogene, 27 (14). pp. 1993-2003. ISSN 1476-5594

Cooper, C. S. ORCID: https://orcid.org/0000-0003-2013-8042 and Foster, C. S. (2008) Concepts of epigenetics in prostate cancer development. British Journal of Cancer, 100 (2). pp. 240-245. ISSN 0007-0920

Cooper, Colin ORCID: https://orcid.org/0000-0003-2013-8042 (2008) Editorial comment on:ADAM9 expression is a significant and independent prognostic marker of PSA relapse in prostate cancer. European Urology, 54 (5). pp. 1107-8. ISSN 0302-2838

E

Edwards, Dylan R. ORCID: https://orcid.org/0000-0002-3292-2064, Handsley, Madeleine M. ORCID: https://orcid.org/0000-0001-8815-006X and Pennington, Caroline J. (2008) The ADAM Metalloproteinases. Molecular Aspects of Medicine, 29 (5). pp. 258-289. ISSN 1872-9452

Eeles, Rosalind A., Kote-Jarai, Zsofia, Giles, Graham G., Olama, Ali Amin Al, Guy, Michelle, Jugurnauth, Sarah K., Mulholland, Shani, Leongamornlert, Daniel A., Edwards, Stephen M., Morrison, Jonathan, Field, Helen I., Southey, Melissa C., Severi, Gianluca, Donovan, Jenny L., Hamdy, Freddie C., Dearnaley, David P., Muir, Kenneth R., Smith, Charmaine, Bagnato, Melisa, Ardern-Jones, Audrey T., Hall, Amanda L., O'Brien, Lynne T., Gehr-Swain, Beatrice N., Wilkinson, Rosemary A., Cox, Angie, Lewis, Sarah, Brown, Paul M., Jhavar, Sameer G., Tymrakiewicz, Malgorzata, Lophatananon, Artitaya, Bryant, Sarah L., Horwich, Alan, Huddart, Robert A., Khoo, Vincent S., Parker, Christopher C., Woodhouse, Christopher J., Thompson, Alan, Christmas, Tim, Ogden, Chris, Fisher, Cyril, Jamieson, Charles, Cooper, Colin S. ORCID: https://orcid.org/0000-0003-2013-8042, English, Dallas R., Hopper, John L., Neal, David E. and Easton, Douglas F. (2008) Multiple newly identified loci associated with prostate cancer susceptibility. Nature Genetics, 40 (3). pp. 316-321. ISSN 1546-1718

F

Folgueras, Alicia R., Fueyo, Antonio, Garcia-Suarez, Olivia, Cox, Jennifer, Astudillo, Aurora, Tortorella, Paolo, Campestre, Cristina, Gutierrez-Fernandez, Ana, Fanjul-Fernandez, Miriam, Pennington, Caroline J., Edwards, Dylan R. ORCID: https://orcid.org/0000-0002-3292-2064, Overall, Christopher M. and Lopez-Otin, Carlos (2008) Collagenase-2 deficiency or inhibition impairs experimental autoimmune encephalomyelitis in mice. Journal of Biological Chemistry, 283 (14). pp. 9465-9474. ISSN 0021-9258

G

Gerg, Michael, Kopitz, Charlotte, Schaten, Susanne, Tschukes, Alexander, Kahlert, Christoph, Stangl, Manfred, von Weyhern, Claus W. H., Brucher, Björn L. D. M., Edwards, Dylan R. ORCID: https://orcid.org/0000-0002-3292-2064, Brand, Karsten and Kruger, Achim (2008) Distinct functionality of tumour cell-derived gelatinases during formation of liver metastases. Molecular Cancer Research, 6 (3). pp. 341-351.

Gukas, Isaac D., Girling, Anne C., Mandong, Barnabas M., Prime, Wendy, Jennings, Barbara A. ORCID: https://orcid.org/0000-0003-3792-9182 and Leinster, Samuel J. (2008) A comparison of clinicopathological features and molecular markers in British and Nigerian women with breast cancer. Clinical Medicine: Oncology, 2. pp. 347-351. ISSN 1177-9314

Gutierrez-Fernandez, Ana, Fueyo, Antonio, Folgueras, Alicia R., Garabaya, Cecilia, Pennington, Caroline J., Pilgrim, Simon, Edwards, Dylan R. ORCID: https://orcid.org/0000-0002-3292-2064, Holliday, Deborah L., Jones, J. Louise, Span, Paul N., Sweep, Fred C. G. J., Puente, Xose S. and López-Otín, Carlos (2008) Matrix Metalloproteinase-8 functions as a metastasis suppressor through modulation of tumour cell adhesion and invasion. Cancer Research, 68 (8). pp. 2755-2763.

I

Inglese, Matilde, Adhya, Sumita, Johnson, Glyn, Babb, James S., Miles, Laura, Jaggi, Hina, Herbert, Joseph and Grossman, Robert I. (2008) Perfusion magnetic resonance imaging correlates of neuropsychological impairment in multiple sclerosis. Journal of Cerebral Blood Flow & Metabolism, 28 (1). pp. 164-171. ISSN 1559-7016

J

Jhavar, Sameer, Reid, Alison, Clark, Jeremy, Kote-Jarai, Zsofia, Christmas, Timothy, Thompson, Alan, Woodhouse, Christopher, Ogden, Christopher, Fisher, Cyril, Corbishley, Cathy, De-Bono, Johann, Eeles, Rosalind, Brewer, Daniel ORCID: https://orcid.org/0000-0003-4753-9794 and Cooper, Colin ORCID: https://orcid.org/0000-0003-2013-8042 (2008) Detection of TMPRSS2-ERG translocations in human prostate cancer by expression profiling using GeneChip Human Exon 1.0 ST arrays. Journal of Molecular Diagnostics, 10 (1). pp. 50-7. ISSN 1525-1578

K

Khandanpour, Nader, Armon, Matthew P., Jennings, Barbara ORCID: https://orcid.org/0000-0003-3792-9182, Clark, Allan ORCID: https://orcid.org/0000-0003-2965-8941 and Meyer, Felicity J. (2008) The association between ankle brachial pressure index and pulse wave velocity. Angiology, 60 (6). pp. 732-738.

Knight, J F, Shepherd, C J, Rizzo, S, Brewer, D ORCID: https://orcid.org/0000-0003-4753-9794, Jhavar, S, Dodson, A R, Cooper, C S ORCID: https://orcid.org/0000-0003-2013-8042, Eeles, R, Falconer, A, Kovacs, G, Garrett, M D, Norman, A R, Shipley, J and Hudson, D L (2008) TEAD1 and c-Cbl are novel prostate basal cell markers that correlate with poor clinical outcome in prostate cancer. British Journal of Cancer, 99 (11). pp. 1849-1858. ISSN 0007-0920

L

Law, Meng, Young, Robert J., Babb, James S., Peccerelli, Nicole, Chheang, Sophie, Gruber, Michael L., Miller, Douglas C., Golfinos, John G., Zagzag, David and Johnson, Glyn (2008) Gliomas: predicting time to progression or survival with cerebral blood volume measurements at dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging. Radiology, 247 (2). pp. 490-498. ISSN 1527-1315

Li, Dan, Wu, Kun, Howie, A. Forbes, Beckett, Geoffrey J., Wang, Wei and Bao, Yongping ORCID: https://orcid.org/0000-0002-6425-0370 (2008) Synergy between broccoli sprout extract and selenium in the upregulation of thioredoxin reductase in human hepatocytes. Food Chemistry, 110 (1). pp. 193-198. ISSN 1873-7072

Lu, H., Pollack, E., Young, R., Babb, J. S., Johnson, G., Zagzag, D., Carson, R., Jensen, J. H., Helpern, J. A. and Law, M. (2008) Predicting grade of cerebral glioma using vascular-space occupancy MR imaging. American Journal of Neuroradiology, 29 (2). pp. 373-8. ISSN 1936-959X

M

Mastrangelo, Lina, Cassidy, Aedin, Mulholland, Francis, Wang, Wei and Bao, Yongping ORCID: https://orcid.org/0000-0002-6425-0370 (2008) Serotonin receptors, novel targets of sulforaphane identified by proteomic analysis in Caco-2 cells. Cancer Research, 68 (13). pp. 5487-5491.

Miles, Laura, Grossman, Robert I., Johnson, Glyn, Babb, James S., Diller, Leonard and Inglese, Matilde (2008) Short-term DTI predictors of cognitive dysfunction in mild traumatic brain injury. Brain Injury, 22 (2). pp. 115-122. ISSN 0269-9052

N

Nielsen, Boye S., Egeblad, Mikala, Rank, Fritz, Askautrud, Hanne A., Pennington, Caroline J., Pedersen, Tanja X., Christensen, Ib J., Edwards, Dylan R. ORCID: https://orcid.org/0000-0002-3292-2064, Werb, Zena and Lund, Leif R. (2008) Matrix metalloproteinase 13 is induced in fibroblasts in polyomavirus middle T antigen-driven mammary carcinoma without influencing tumor progression. PLoS One, 3 (8). ISSN 1932-6203

O

O'Connell, Maria ORCID: https://orcid.org/0000-0002-0267-0951 and Rushworth, Stuart (2008) Curcumin: potential for hepatic fibrosis therapy? British Journal of Pharmacology, 153 (3). pp. 403-405. ISSN 1476-5381

Oddsdottir, C., Riley, S.C., Leask, R., Edwards, D.R. ORCID: https://orcid.org/0000-0002-3292-2064 and Watson, E.D. (2008) Activities of matrix metalloproteinases-9 and -2 in uterine fluid during induced equine endometritis. Pferdeheilkunde, 24. pp. 70-73.

Ogborne, Richard M., Rushworth, Stuart and O'Connell, Maria ORCID: https://orcid.org/0000-0002-0267-0951 (2008) Epigallocatechin activates haem oxygenase-1 expression via protein kinase Cδ and Nrf2. Biochemical and Biophysical Research Communications, 373 (4). pp. 584-588. ISSN 1090-2104

P

Pennington, Caroline J., Nuttall, Robert K., Sampieri-Ramirez, Clara L., Wallard, Matthew, Pilgrim, Simon and Edwards, Dylan R. ORCID: https://orcid.org/0000-0002-3292-2064 (2008) Quantitative real-time PCR analysis of Degradome gene expression. In: The Cancer Degradome: Proteases and Cancer Biology. Springer, pp. 49-65.

Pennington, Caroline J., Pilgrim, Simon, Span, Paul N., Sweep, Fred C. and Edwards, Dylan R. ORCID: https://orcid.org/0000-0002-3292-2064 (2008) Novel Degradome markers in breast cancer. In: The Cancer Degradome: Proteases and Cancer Biology. Springer, pp. 627-643. ISBN 978-0-387-69056-8

R

Rushworth, Stuart A. and MacEwan, David J. (2008) HO-1 underlies resistance of AML cells to TNF-induced apoptosis. Blood, 111 (7). pp. 3793-3801. ISSN 0006-4971

Rushworth, Stuart A., MacEwan, David J. and O'Connell, Maria A. ORCID: https://orcid.org/0000-0002-0267-0951 (2008) Lipopolysaccharide-induced expression of NAD(P)H:quinone oxidoreductase 1 and heme oxygenase-1 protects against excessive inflammatory responses in human monocytes. Journal of Immunology, 181 (10). pp. 6730-6737. ISSN 0022-1767

Rushworth, Stuart A., Taylor, Alison, Langa, Susana and MacEwan, David J. (2008) TNF signaling gets FLIPped off : TNF-induced regulation of FLIP. Cell Cycle, 7 (2). pp. 194-199. ISSN 1538-4101

S

Sampieri, Clara L., Nuttall, Robert K., Young, David A., Goldspink, Deborah, Clark, Ian M. and Edwards, Dylan R. ORCID: https://orcid.org/0000-0002-3292-2064 (2008) Activation of p38 and JNK MAPK pathways abrogates requirement for new protein synthesis for phorbol ester mediated induction of select MMP and TIMP genes. Matrix Biology, 27 (2). pp. 128-138. ISSN 1569-1802

Shepherd, Christopher J, Rizzo, Siân, Ledaki, Ioanna, Davies, Melissa, Brewer, Daniel ORCID: https://orcid.org/0000-0003-4753-9794, Attard, Gerhardt, de Bono, Johann and Hudson, David L (2008) Expression profiling of CD133+ and CD133- epithelial cells from human prostate. The Prostate, 68 (9). pp. 1007-24. ISSN 0270-4137

Shukla, Chitranjan J., Pennington, Caroline J., Riddick, Antony C. P., Sethia, Krishna K., Ball, Richard Y. and Edwards, Dylan R. ORCID: https://orcid.org/0000-0002-3292-2064 (2008) Laser capture microdissection in prostate cancer research: establishment and validation of a powerful tool for the assessment of tumour-stroma interactions. British Journal of Urology, 101 (6). pp. 765-774.

Stewart, G.D., Skipworth, R.J., Pennington, C.J., Lowrie, A.G., Deans, D.A., Edwards, D.R. ORCID: https://orcid.org/0000-0002-3292-2064, Habib, F.K., Riddick, A.C., Fearon, K.C. and Ross, J.A. (2008) Variation in dermcidin expression in a range of primary human tumours and in hypoxic/oxidatively stressed human cell lines. British Journal of Cancer, 99. pp. 126-132.

Stewart, Grant D., Gray, Kelly, Pennington, Caroline J., Edwards, Dylan R. ORCID: https://orcid.org/0000-0002-3292-2064, Riddick, Antony C. P., Ross, James A. and Habib, Fouad K. (2008) Analysis of hypoxia-associated gene expression in prostate cancer: lysyl oxidase and glucose transporter-1 expression correlate with Gleason score. Oncology Reports, 20 (6). pp. 1561-1567. ISSN 1791-2431

T

Tanabe, Jody, Crowley, Thomas, Hutchison, Kent, Miller, David, Johnson, Glyn, Du, Yiping P., Zerbe, Gary and Freedman, Robert (2008) Ventral striatal blood flow is altered by acute nicotine but not withdrawal from nicotine. Neuropsychopharmacology, 33 (3). pp. 627-633. ISSN 0893-133X

V

Vergis, Roy, Corbishley, Catherine M, Norman, Andrew R, Bartlett, Jaclyn, Jhavar, Sameer, Borre, Michael, Heeboll, Sara, Horwich, Alan, Huddart, Robert, Khoo, Vincent, Eeles, Ros, Cooper, Colin ORCID: https://orcid.org/0000-0003-2013-8042, Sydes, Matthew, Dearnaley, David and Parker, Chris (2008) Intrinsic markers of tumour hypoxia and angiogenesis in localised prostate cancer and outcome of radical treatment:a retrospective analysis of two randomised radiotherapy trials and one surgical cohort study. The Lancet Oncology, 9 (4). pp. 342-351. ISSN 1470-2045

Y

Yu, Xin, Zou, Jing, Babb, James S., Johnson, Glyn, Sanes, Dan H. and Turnbull, Daniel H. (2008) Statistical mapping of sound-evoked activity in the mouse auditory midbrain using Mn-enhanced MRI. NeuroImage, 39 (1). pp. 223-230. ISSN 1053-8119

Z

Zhong, Julia L., Poghosyan, Zaruhi, Pennington, Caroline J., Scott, Xanthe, Handsley, Madeleine M. ORCID: https://orcid.org/0000-0001-8815-006X, Warn, Alba, Gavrilovic, Jelena ORCID: https://orcid.org/0000-0002-5312-1784, Honert, Katja, Krüger, Achim, Span, Paul N., Sweep, Fred C. G. J. and Edwards, Dylan R. ORCID: https://orcid.org/0000-0002-3292-2064 (2008) Distinct functions of natural ADAM-15 cytoplasmic domain variants in human mammary carcinoma. Molecular Cancer Research, 6 (3). pp. 383-394.