Items where Research Group is "Medicinal Chemistry

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Number of items: 21.

C

Cecioni, Samy, Lalor, Ruth, Blanchard, Bertrand, Praly, Jean-Pierre, Imberty, Anne, Matthews, Susan E. ORCID: https://orcid.org/0000-0001-8821-0851 and Vidal, Sebastien (2009) Achieving high affinity towards a bacterial lectin through multivalent topological isomers of calix[4]arene glycoconjugates. Chemistry - A European Journal, 15 (47). pp. 13232-13240. ISSN 0947-6539

Clark, Ryan C., Lee, Sang Yeul, Hwang, Inkyu, Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949 and Boger, Dale L. (2009) Evaluation of chlorofusin, its seven chromophore diastereomers, and key analogues. Tetrahedron Letters, 50 (26). pp. 3151-3153.

Clark, Ryan C., Lee, Sang Yeul, Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949 and Boger, Dale L. (2009) The isolation, total synthesis and structure elucidation of chlorofusin, a natural product inhibitor of the p53–MDM2 protein–protein interaction. Natural Product Reports, 26 (4). pp. 465-477. ISSN 1460-4752

Collingwood, S., Lock, R. and Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949 (2009) Optimizing drugs for local delivery. Drug News & Perspectives, 22 (10). pp. 627-634. ISSN 0214-0934

D

Dawson, S., Searcey, M. ORCID: https://orcid.org/0000-0003-2273-8949, Hampshire, A., Fox, K. and Malkinson, J. (2009) Solid-phase-based synthesis and biological evaluation of novel chromophore analogues of the bis-intercalator TANDEM. Biopolymers, 92 (4). p. 367. ISSN 0006-3525

G

Ganesan, A ORCID: https://orcid.org/0000-0003-4862-7999, Nolan, L, Crabb, SJ and Packham, G (2009) Epigenetic Therapy: Histone Acetylation, DNA Methylation and Anti-Cancer Drug Discovery. Current Cancer Drug Targets, 9 (8). pp. 963-981. ISSN 1568-0096

Ghosh, N., Sheldrake, H. M., Searcey, M. ORCID: https://orcid.org/0000-0003-2273-8949 and Pors, K. (2009) Chemical and Biological Explorations of the Family of CC-1065 and the Duocarmycin Natural Products. Current Topics in Medicinal Chemistry, 9 (16). pp. 1494-1524. ISSN 1568-0266

H

Howell, L. A. and Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949 (2009) Targeting the Holliday junction: Design and synthesis of acridine-3/4-carboxamide analogs using click chemistry. Abstracts of Papers of the American Chemical Society, 238. 210-ORGN. ISSN 0065-7727

Howell, Lesley, Howman, Aaron, O'Connell, Maria ORCID: https://orcid.org/0000-0002-0267-0951, Mueller, Anja ORCID: https://orcid.org/0000-0003-0774-0434 and Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949 (2009) Synthesis and evaluation of 9-aminoacridines derived from benzyne click chemistry. Bioorganic & Medicinal Chemistry Letters, 19 (20). pp. 5880-5883. ISSN 1464-3405

Howell, Lesley and Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949 (2009) Targeting Higher-Order DNA: Beyond the G-Quadruplex. ChemBioChem, 10 (13). pp. 2139-2143. ISSN 1439-7633

I

Iijima, Yusuke, Munakata, Asami, Shin-ya, Kazuo, Ganesan, A. ORCID: https://orcid.org/0000-0003-4862-7999, Doi, Takayuki and Takahashi, Takashi (2009) A solid-phase total synthesis of the cyclic depsipeptide HDAC inhibitor spiruchostatin A. Tetrahedron Letters, 50 (24). pp. 2970-2972.

M

Moore, Deborah and Matthews, Susan E. ORCID: https://orcid.org/0000-0001-8821-0851 (2009) O-alkyl resorcarenes: where are we now? Journal of Inclusion Phenomena and Macrocyclic Chemistry, 65 (1-2). pp. 137-155. ISSN 0923-0750

N

Naylor, Edmund, Arredouani, Abdelilah, Vasudevan, Sridhar R., Lewis, Alexander M., Parkesh, Raman, Mizote, Akiko, Rosen, Daniel, Thomas, Justyn M., Izumi, Minoru, Ganesan, A. ORCID: https://orcid.org/0000-0003-4862-7999, Galione, Antony and Churchill, Grant C. (2009) Identification of a chemical probe for NAADP by virtual screening. Nature Chemical Biology, 5 (4). pp. 220-226. ISSN 1552-4450

Newton, Gerald L., Rawat, Mamta, La Clair, James J., Jothivasan, Vishnu Karthik, Budiarto, Tanya, Hamilton, Chris J., Claiborne, Al, Helmann, John D. and Fahey, Robert C. (2009) Bacillithiol is an antioxidant thiol produced in Bacilli. Nature Chemical Biology, 5 (9). pp. 625-627. ISSN 1552-4450

R

Rosen, Daniel, Lewis, Alexander M., Mizote, Akiko, Thomas, Justyn M., Aley, Parvinder K., Vasudevan, Sridhar R., Parkesh, Raman, Galione, Antony, Izumi, Minoru, Ganesan, A. ORCID: https://orcid.org/0000-0003-4862-7999 and Churchill, Grant C. (2009) Analogues of the Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) Antagonist Ned-19 Indicate Two Binding Sites on the NAADP Receptor. Journal of Biological Chemistry, 284 (50). pp. 34930-34934. ISSN 0021-9258

Rowan, Andrew S., Nicely, Nathan I., Cochrane, Nicola, Wlassoff, Wjatschesslaw A., Claiborne, Al and Hamilton, Chris J. (2009) Nucleoside triphosphate mimicry: a sugar triazolyl nucleoside as an ATP-competitive inhibitor of B. anthracis pantothenate kinase. Organic & Biomolecular Chemistry, 7 (19). pp. 4029-4036. ISSN 1477-0520

S

Shaginian, Alex, Whitby, Landon R., Hong, Sukwon, Hwang, Inkyu, Farooqi, Bilal, Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949, Chen, Jiandong, Vogt, Peter K. and Boger, Dale L. (2009) Design, synthesis, and evaluation of an a-helix mimetic library targeting protein-protein interactions. Journal of the American Chemical Society, 131 (15). pp. 5564-5572.

Sharp, Adam, Crabb, Simon J., Johnson, Peter W. M., Hague, Angela, Cutress, Ramsey, Townsend, Paul A., Ganesan, A. ORCID: https://orcid.org/0000-0003-4862-7999 and Packham, Graham (2009) Thioflavin S (NSC71948) Interferes with Bcl-2-Associated Athanogene (BAG-1)-Mediated Protein-Protein Interactions. Journal of Pharmacology and Experimental Therapeutics, 331 (2). pp. 680-689. ISSN 0022-3565

Stewart, Matthew J. G., Jothivasan, Vishnu Karthik, Rowan, Andrew S., Wagg, Jennifer and Hamilton, Chris J. (2009) Mycothiol disulfide reductase: solid phase synthesis and evaluation of alternative substrate analogues. Organic & Biomolecular Chemistry, 6 (2). pp. 385-390. ISSN 1477-0520

W

Waller, Zoë A. E., Sewitz, Sven A., Hsu, Shang-Te Danny and Balasubramanian, Shankar (2009) A small molecule that disrupts G-quadruplex DNA structure and enhances gene expression. Journal of the American Chemical Society, 131 (35). pp. 12628-12633.

Watanabe, Kenji, Hotta, Kinya, Praseuth, Alex P., Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949, Wang, Clay C. C., Oguri, Hiroki and Oikawa, Hideaki (2009) Rationally engineered total biosynthesis of a synthetic analogue of a natural quinomycin depsipeptide in Escherichia coli. ChemBioChem, 10 (12). pp. 1965-1968. ISSN 1439-7633

This list was generated on Sat Feb 4 12:05:23 2023 UTC.