Items where Research Group is "Norwich Clinical Trials Unit

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Number of items: 77.


Akowuah, E, Gray, C, Francis, S, Gunn, J, Bettinger, T, Brisken, A, Crossman, D and Newman, C (2003) Adjunctive ultrasound exposure enhances gene delivery to vascular smooth muscle cells in vitro and to ex vivo and in vivo porcine saphenous vein grafts. In: 15th Annual Transcatheter Cardiovascular Therapeutics Symposium, 2003-09-15 - 2003-09-19.

Al-Rabia, MW, Blaylock, MG, Sexton, DW, Thomson, L and Walsh, GM (2003) Granule protein changes and membrane receptor phenotype in maturing human eosinophils cultured from CD34+ progenitors. Clinical and Experimental Allergy, 33 (5). pp. 640-648. ISSN 1365-2222

Ashworth, Mark, Godfrey, Emma, Harvey, Kate and Darbishire, Lucy ORCID: (2003) Perceptions of psychological content in the GP consultation—the role of practice, personal and prescribing attributes. Family Practice, 20 (4). pp. 373-375. ISSN 0263-2136


Bakhai, Ameet, Flather, Marcus D., Collinson, Julian R., Stevens, Warren, Normand, Charles, Alemao, Evo, Itzler, Robbin and Ben-Joseph, Rami (2003) National economic impact of tirofiban for unstable angina and myocardial infarction without ST elevation; example from the United Kingdom. International Journal of Cardiology, 91 (2-3). pp. 163-172. ISSN 0167-5273

Barton, Garry R., Bloor, Karen E., Marshall, David H. and Summerfield, A. Quentin (2003) Paediatric cochlear implantation: multi-centre retrospective cost analysis. International Journal of Pediatric Otorhinolaryngology, 67 (2). pp. 141-149. ISSN 1872-8464

Barton, Garry R., Davis, Adrian C., Parving, Agnete, Roine, Risto, Sorri, Martti and Stilven, Staffan (2003) Cross-sectional survey of adult hearing aid services in Denmark, Finland & the UK. Audiological Medicine, 1 (2). pp. 107-114. ISSN 1651-3835

Blyth, Annie, Musgrave, Stan, Price, David and Harvey, Ian (2003) Pragmatic research tales: The ELEVATE study as an illustration of the issues involved in implementing pragmatic research. Primary Care Respiratory Journal, 12 (3). p. 95. ISSN 1475-1534

Budaj, Andrzej, Brieger, David, Steg, Ph Gabriel, Goodman, Shaun G, Dabbous, Omar H, Fox, Keith A A, Avezum, Alvaro, Cannon, Christopher P, Mazurek, Tomasz, Flather, Marcus D and Van De Werf, Frans and GRACE Investigators (2003) Global patterns of use of antithrombotic and antiplatelet therapies in patients with acute coronary syndromes:insights from the Global Registry of Acute Coronary Events (GRACE). American Heart Journal, 146 (6). pp. 999-1006. ISSN 0002-8703


Cha, Soonmee, Johnson, Glyn, Wadghiri, Youssef Zaim, Jin, Olivier, Babb, Jim, Zagzag, David and Turnbull, Daniel H. (2003) Dynamic, contrast-enhanced perfusion MRI in mouse gliomas: correlation with histopathology. Magnetic Resonance in Medicine, 49 (5). pp. 848-855. ISSN 0740-3194

Chester, R. ORCID:, Costa, M. L., Shepstone, L. and Donell, S. T. (2003) Reliability of computer dynamometry in assessing functional recovery of Achilles tendon ruptures. Foot and Ankle International, 24 (12). pp. 909-915. ISSN 1944-7876

Chester, Rachel ORCID:, Costa, Matthew L., Shepstone, Lee and Donell, Simon T. (2003) Reliability of isokinetic dynamometry in assessing plantarflexion torque following Achilles tendon rupture. Foot & Ankle International, 24 (12). pp. 909-915. ISSN 1071-1007

Clark, AB ORCID: and Lawson, A (2003) A directional derivative approach to spatio-temporal monitoring of disease. In: American Statistical Association Annual Meeting, 2003-01-01.

Coats, Andrew J S, Henein, Michael, Flather, Marcus, Sigwart, Ulrich, Seggewiss, Hubert, Wang, Duolao, Yousufuddin, Mohammed and Shamim, Waqar (2003) Retraction:Shamim et Al. Nonsurgical reduction of the interventricular septum in patients with hypertrophic cardiomyopathy. N Engl J Med 2002;347:1326-33. New England Journal of Medicine, 348 (10). p. 951. ISSN 0028-4793

Cooper, Nicola J., Abrams, Keith R., Sutton, Alex J., Turner, David ORCID: and Lambert, Paul C. (2003) A Bayesian approach to Markov modelling in cost-effectiveness analyses: application to taxane use in advanced breast cancer. Journal of the Royal Statistical Society: Series A, 166 (3). pp. 389-405. ISSN 0964-1998

Cooper, Nicola J., Sutton, Alexander J., Abrams, Keith R., Wailoo, Allan, Turner, David ORCID: and Nicholson, Karl G. (2003) Effectiveness of neuraminidase inhibitors in treatment and prevention of influenza A and B: systematic review and meta-analyses of randomised controlled trials. British Medical Journal (BMJ), 326 (7401). p. 1235. ISSN 0959-8138

Costa, M. L., Shepstone, L, Darrah, C., Marshall, A. T. and Donell, S. T. (2003) Immediate full-weight-bearing mobilisation for repaired Achilles tendon ruptures: a pilot study. Injury, 34 (11). pp. 874-876.

Currie, GP, Haggart, K, Lee, DK, Fowler, SJ, Wilson, AM, Brannan, JD, Anderson, SD and Lipworth, BJ (2003) Effects of histamine and leukotriene antagonism on mannitol and adenosine monophosphate challenges. Clinical and Experimental Allergy, 33 (6). pp. 783-788. ISSN 1365-2222


Danvers, Lesley, Freshwater, Dawn, Cheater, Francine and Wilson, Andrew (2003) Providing a seamless service for children with life-limiting illness: Experiences and recommendations of professional staff at the Diana Princess of Wales Children's Community Service. Journal of Clinical Nursing, 12 (3). pp. 351-359. ISSN 0962-1067

Darbishire, L. ORCID:, Ridsdale, L. and Seed, P. T. (2003) Distinguishing patients with chronic fatigue from those with chronic fatigue syndrome:A diagnostic study in UK primary care. British Journal of General Practice, 53 (491). pp. 441-445. ISSN 0960-1643

Dewberry, Rachael M., Crossman, David C. and Francis, Sheila E. (2003) Interleukin-1 receptor antagonist (IL-1RN) genotype modulates the replicative capacity of human endothelial cells. Circulation Research, 92 (12). pp. 1285-1287. ISSN 0009-7330


Flather, Marcus D and Mallick, Umair (2003) Women responded to an early invasive strategy as well as men in the acute coronary syndrome. ACP Journal Club, 139 (1). p. 3. ISSN 1056-8751

Fox, Keith A. A., Goodman, Shaun G., Anderson, Frederick A., Granger, Christopher B., Moscucci, Mauro, Flather, Marcus D., Spencer, Frederick, Budaj, Andrzej, Dabbous, Omar H. and Gore, Joel M. and GRACE Investigators (2003) From guidelines to clinical practice: The impact of hospital and geographical characteristics on temporal trends in the management of acute coronary syndromes. The Global Registry of Acute Coronary Events (GRACE). European Heart Journal, 24 (15). pp. 1414-1424. ISSN 0195-668X

Furness, Peter N., Philpott, Carl M. ORCID:, Chorbadjian, Mary T., Nicholson, Michael L., Bosmans, Jean-Louis, Corthouts, Bob L., Bogers, Johannes J. P. M., Schwarz, Anke, Gwinner, Wilfried, Haller, Hermann, Mengel, Michael, Seron, Daniel, Moreso, Francesc and Cañas, Conception (2003) Protocol biopsy of the stable renal transplant: a multicenter study of methods and complication rates. Transplantation, 76 (6). pp. 969-973. ISSN 0041-1337


Granger, Christopher B., Goldberg, Robert J., Dabbous, Omar, Pieper, Karen S., Eagle, Kim A., Cannon, Christopher P., van de Werf, Frans, Avezum, Alvaro, Goodman, Shaun G., Flather, Marcus D and Fox, Keith A. A. and Global Registry of Acute Coronary Events Investigators (2003) Predictors of hospital mortality in the global registry of acute coronary events. Archives of Internal Medicine, 163 (19). pp. 2345-2353. ISSN 0003-9926

Gunn, J, Morton, A C, Wales, C, Newman, C M H, Crossman, DC and Cumberland, D C (2003) Drug eluting stents: maximising benefit and minimising cost. Heart, 89 (2). pp. 127-131. ISSN 1355-6037

Gunn, Julian, Crossman, David, Grech, Ever D. and Cumberland, David (2003) New developments in percutaneous coronary intervention. British Medical Journal (BMJ), 327 (7407). pp. 150-153. ISSN 0959-8138


Hand, C, Shepstone, L and Dawson, H (2003) Judging the quality of senior house officer training: The work of the Hospital Recognition Committee of the Royal College of General Practitioners in England and Northern Ireland. Education for Primary Care, 14 (1). pp. 18-24. ISSN 1475-990X

Hauser, Elizabeth R., Mooser, Vincent, Crossman, David C., Haines, Jonathan L., Jones, Christopher H., Winkelmann, Bernhard R., Schmidt, Silke, Scott, William K., Roses, Allen D., Pericak-Vance, Margaret A., Granger, Christopher B. and Kraus, William E. (2003) Design of the Genetics of Early Onset Cardiovascular Disease (GENECARD) study. American Heart Journal, 145 (4). pp. 602-613. ISSN 0002-8703

Hay, Alastair D., Wilson, Andrew, Fahey, Tom and Peters, Tim J. (2003) The duration of acute cough in pre-school children presenting to primary care: a prospective cohort study. Family Practice, 20 (6). pp. 696-705. ISSN 0263-2136


Jones, Matthew, Tallis, Raymond and Pomeroy, Valerie ORCID: (2003) Physiotherapists may not practice what is implied from treatment 'labels'. Age and Ageing, 32 (2). pp. 229-230. ISSN 1468-2834

Joyner, Campbell D and Flather, Marcus (2003) Statistical versus clinical significance of the CURE study in acute coronary syndromes. Journal of the American College of Cardiology, 41 (7). 1233-4; author reply 1234-5. ISSN 0735-1097


King, Andrea R., Francis, Sheila E., Bridgeman, Collette J., Bird, Helen, Whyte, Moira K. B. and Crossman, David C. (2003) A role for caspase-1 in serum withdrawal-induced apoptosis of endothelial cells. Laboratory Investigation, 83 (10). pp. 1497-1508. ISSN 0023-6837


Law, Meng, Yang, Stanley, Wang, Hao, Babb, James S., Johnson, Glyn, Cha, Soonmee, Knopp, Edmond A. and Zagzag, David (2003) Glioma grading: sensitivity, specificity, and predictive values of perfusion MR imaging and proton MR spectroscopic imaging compared with conventional MR imaging. American Journal of Neuroradiology, 24 (10). pp. 1989-1998. ISSN 1936-959X

Lawrie, Allan, Brisken, Axel F, Francis, Sheila E, Wyllie, David, Kiss-Toth, Endre, Qwarnstrom, Eva E, Dower, Stephen K, Crossman, David C. and Newman, Christopher M (2003) Ultrasound-enhanced transgene expression in vascular cells is not dependent upon cavitation-induced free radicals. Ultrasound in Medicine & Biology, 29 (10). pp. 1453-1461. ISSN 0301-5629

Lawson, A and Clark, AB ORCID: (2003) Bayesian Spatial Health Surveillance (Invited Oral Presentation). In: DIMACS Tutorial on Statistical and Other Analytic Health Surveillance Methods, 2003-01-01.

Lawson, A, Vidal-Rodeiro, CL and Clark, AB ORCID: (2003) New statistical methodologies for syndromic surveillance. In: 2nd National syndromic surveillance conference (Poster presentation), New York, 2003-01-01.

Lee, Daniel K. C., Robb, Fiona M., Sims, Erika J. ORCID:, Currie, Graeme P., McFarlane, Lesley C. and Lipworth, Brian J. (2003) Systemic bioactivity of intranasal triamcinolone and mometasone in perennial allergic rhinitis. British Journal of Clinical Pharmacology, 55 (3). pp. 310-313. ISSN 1365-2125

Liew, L, Philpott, C ORCID:, Kendall, C, Pringle, J and Banerjee, AR (2003) Benzopyrene-diol epoxide DNA adducts in laryngeal tissue. Journal of Laryngology & Otology, S29 (117). p. 45. ISSN 1748-5460

Lindqvist, SM ORCID:, Duncan, A, Shepstone, L, Watts, AF and Pearce, S (2003) Working together - from the start. Lifelong Learning Building the continuum of professional and interprofessional learning for health and social care'. In: Royal College of Obstetricians and Gynaecologists, London, 2003-01-01.

Lindqvist, SM ORCID:, Duncan, A, Shepstone, L, Watts, AF and Pearce, S (2003) Working together a message from our students. In: Nordic interprofesional network conference, Oulu, Finland, 2003-01-01.

Lu, Stanley, Ahn, Daniel, Johnson, Glyn and Cha, Soonmee (2003) Peritumoral diffusion tensor imaging of high-grade gliomas and metastatic brain tumors. American Journal of Neuroradiology, 24 (5). pp. 937-941. ISSN 1936-959X


Manning, C. D. and Pomeroy, V. M. ORCID: (2003) The effectiveness of treadmill retraining on the gait of hemiparetic stroke patients: a systematic review of current evidence. Physiotherapy, 89 (6). pp. 337-349. ISSN 1873-1465

McCrone, P., Darbishire, L. ORCID:, Ridsdale, L. and Seed, P. (2003) The economic cost of chronic fatigue and chronic syndrome in UK primary care. Psychological Medicine, 33 (2). pp. 253-261. ISSN 0033-2917

McCrone, Paul, Darbishire, Lucy ORCID:, Ridsdale, Leone and Seed, Paul T (2003) Chronic fatigue has high, but mainly hidden, costs. Evidence-based Healthcare. pp. 196-197.

Morton, Allison, Papadopoulos, Thomas, Wales, Clare, Bowes, Robert, Campbell, Stephen, Oakley, David, Wheeldon, Nigel, Newman, Christopher, Crossman, David C., Cumberland, David and Gunn, Julian (2003) Real world small vessel coronary artery stenting: an analysis. British Journal Cardiology. (Acute & Intervent), 10 (28). pp. 28-32.

Morton, A, Varcoe, R, Beacock, D, Crossman, D and Gunn, J (2003) Same-session discharge after PCI. In: Annual Scientific Conference of the British-Cardiac-Society, 2003-04-28 - 2003-05-01.


Pannett, A. A. J., Kennedy, A. M., Turner, J. J. O., Forbes, S. A., Cavaco, B. M., Bassett, J. H. D., Cianferotti, L., Harding, B., Shine, B., Flinter, F., Maidment, C. G. H., Trembath, R. and Thakker, R. V. (2003) Multiple endocrine neoplasia type 1 (MEN1) germline mutations in familial isolated primary hyperparathyroidism. Clinical Endocrinology, 58 (5). pp. 639-646. ISSN 0300-0664

Pollard, S D, Munks, K, Wales, C, Crossman, DC, Cumberland, D C, Oakley, G D G and Gunn, J (2003) Position and Mobilisation Post-Angiography Study (PAMPAS): a comparison of 4.5 hours and 2.5 hours bed rest. Heart, 89 (4). pp. 447-448. ISSN 1355-6037

Pollock, Alex, Baer, Gillian, Pomeroy, Valerie M. ORCID: and Langhorne, Peter (2003) Physiotherapy treatment approaches for the recovery of postural control and lower limb function following stroke. Cochrane Database of Systematic Reviews, 4 CD001920. ISSN 1465-1858

Pomeroy, V. M. ORCID:, Mickelborough, J., Hill, E., Rodgers, P. and Giakas, G. (2003) A hypothesis: self-propulsion in a wheelchair early post-stroke might not be harmful. Clinical Rehabilitation, 17 (2). pp. 174-180.

Pomeroy, V. M. ORCID:, Pramanik, A., Sykes, L., Richards, J. and Hill, E. (2003) Agreement between physiotherapists on quality of movement rated via videotape. Clinical Rehabilitation, 17 (3). pp. 264-272.


Richards, J. D., Pramanik, A., Sykes, L. and Pomeroy, V. M. ORCID: (2003) A comparison of knee kinematic characteristics of stroke patients and age-matched healthy volunteers. Clinical Rehabilitation, 17 (5). pp. 565-571.

Richardson, B, Shepstone, L, Poland, F ORCID:, Mugford, M, Cox, H, Mohseni-Bandpei, MA, Finlayson, B, Knights, C, Christie, S, Clemence, N and Francis, R (2003) A Randomised Controlled Trial Comparing Initial Physiotherapy Assessment and Management with Routine Practice For Selected Patients in an A&E department of an Acute Hospital. In: UNSPECIFIED.


Saw, N. L., Jones, S., Shepstone, L., Meyer, M., Chapman, P. G. and Logan, A. M. (2003) Early outcome and cost-effectiveness of endoscopic versus open carpal tunnel release: a randomized prospective trial. Journal of Hand Surgery-British, 28 (5). pp. 444-449.

Sexton, DW (2003) Comparsion of phagocytosis of apoptotic granulocytes by airway epithelial cell and monocyte-derived macrophages. In: 13th Annual Congress of the European Respiratory Society (ERS), 2003-01-01.

Shepstone, L (2003) Statistical Properties of OARSI type Responder definitions. In: Osteoarthritis and Research Society, Berlin 2003, 2003-01-01.

Shepstone, L and Cline, GA (2003) Statistical properties of OARSI type responder definitions. In: 67th Annual Scientific Meeting of the American College of Rheumatology/38th Annual Scientific Meeting of the Association of Rheumatology Health Professionals, 2003-10-23 - 2003-10-28.

Sheridan, Paul J and Crossman, DC (2003) Diagnosing chronic stable angina. The Practitioner, 247 (1644). pp. 208-215. ISSN 0032-6518

Sims, Erika J. ORCID:, Jackson, Catherine M. and Lipworth, Brian J. (2003) Add-on therapy with montelukast or formoterol in patients with the glycine-16 beta2-receptor genotype. British Journal of Clinical Pharmacology, 56 (1). pp. 104-111. ISSN 1365-2125

Stacey, Joanna M., Turner, Jeremy J. O., Harding, Brian, Nesbit, M. Andrew, Kotanko, Peter, Lhotta, Karl, Puig, Juan G., Torres, Rosa J. and Thakker, Rajesh V. (2003) Genetic mapping studies of familial juvenile hyperuricemic nephropathy on chromosome 16p11-p13. Journal of Clinical Endocrinology & Metabolism, 88 (1). pp. 464-470. ISSN 1945-7197

Stevens, CA, Turner, D ORCID:, Kuehni, CE, Couriel, JM and Silverman, M (2003) The economic impact of preschool asthma and wheeze. European Respiratory Journal, 21 (6). pp. 1000-1006. ISSN 0903-1936

Summerfield, A. Quentin, Stacey, Paula C., Roberts, Katherine L., Fortnum, Heather M. and Barton, Garry R. (2003) Economic prioritisation of cochlear implantation. International Congress Series, 1254. pp. 313-319.

Swart, Ann Marie ORCID:, Trimbos, J.B., Parmar, M., Guthrie, D., Vergote, I., Bolis, G., Colombo, N., Vermorken, J.B., Torri, V., Mangioni, C. and Pecorelli, S. (2003) International collaborative ovarian neoplasm trial 1 and adjuvant chemotherapy in ovarian neoplasm trial:Two parallel randomized phase III trials of adjuvant chemotherapy in patients with early-stage ovarian carcinoma. Journal of the National Cancer Institute, 95 (2). pp. 105-112. ISSN 0027-8874

Swart, Ann Marie and Guthrie, David (2003) Adjuvant chemotherapy in "Early" stage ovarian cancer. American Journal of Oncology Review. pp. 122-126.


Turner, David ORCID:, Wailoo, A, Nicholson, K, Cooper, N, Sutton, A and Abrams, K (2003) Systematic review and economic decision modelling for the prevention and treatment of influenza A and B. Health Technology Assessment, 7 (35). ISSN 2046-4924

Turner, J. J. O., Stacey, J. M., Harding, B., Kotanko, P., Lhotta, K., Puig, J. G., Roberts, I., Torres, R. J. and Thakker, R. V. (2003) UROMODULIN mutations cause familial juvenile hyperuricemic nephropathy. Journal of Clinical Endocrinology & Metabolism, 88 (3). pp. 1398-1401. ISSN 1945-7197


Walsh, GM, Sexton, DW and Blaylock, MG (2003) Corticosteroids, eosinophils and bronchial epithelial cells: new insights into the resolution of inflammation in asthma. Journal of Endocrinology, 178 (1). pp. 37-43. ISSN 1479-6805

Wetzel, Stephan G., Law, Meng, Lee, Vivian S., Cha, Soonmee, Johnson, Glyn and Nelson, Kim (2003) Imaging of the intracranial venous system with a contrast-enhanced volumetric interpolated examination. European Radiology, 13 (5). pp. 1010-1018. ISSN 0938-7994

Wilson, AM (2003) Are Antihistamines Useful in Managing Asthma? In: World Allergy Organisation Congress, 2003-01-01.

Wilson, AM (2003) Objective measurement of airways inflammation. In: The Scientific meeting of the Association of Allergists and Clinical Immunologists of Quebec, Quebec, 2003-01-01.

Wilson, Andrew D. H., Hart, Andrew, Brannstrom, Thomas, Wiberg, Mikael and Terenghi, Giorgio (2003) Primary sensory neuronal rescue with systemic acetyl-L-carnitine following peripheral axotomy. A dose-response analysis. British Journal of Plastic Surgery, 56 (8). pp. 732-739. ISSN 0007-1226

Wilson, Andrew M., Coutie, Wendy J. R., Sims, Erika J. ORCID: and Lipworth, Brian J. (2003) The skin vasoconstrictor assay does not correlate significantly to airway or systemic responsiveness to inhaled budesonide in asthmatic patients. European Journal of Clinical Pharmacology, 58 (10). pp. 643-647.

Wilson, Andrew M., Orr, Linda C., Robb, Fiona, Sims, Erika J. ORCID: and Lipworth, Brian J. (2003) Reproducibilty of nasal function measurements with histamine and adenosine monophosphate nasal challenge testing in patients with allergic rhinitis. Allergology International, 52 (3). pp. 155-160. ISSN 1440-1592

Wilson, Andrew M., Sims, Erika J. ORCID:, Orr, Linda C., Robb, Fiona and Lipworth, Brian J. (2003) An evaluation of short-term corticosteroid response in perennial allergic rhinitis using histamine and adenosine monophosphate nasal challenge. British Journal of Clinical Pharmacology, 55 (4). pp. 354-359. ISSN 1365-2125

Wilson, Andrew M., Sims, Erika J. ORCID:, Robb, Fiona, Cockburn, Wendy and Lipworth, Brian J. (2003) Peak inspiratory flow rate is more sensitive than acoustic rhinometry or rhinomanometry in detecting corticosteroid response with nasal histamine challenge. Rhinology, 41 (1). pp. 16-20.

Wilson, Andrew M., Thabane, Lehana and Holbrook, Anne (2003) Application of data mining techniques in pharmacovigilance. British Journal of Clinical Pharmacology, 57 (2). pp. 127-134. ISSN 1365-2125


Yang, Stanley, Law, Meng, Zagzag, David, Wu, Hope H., Cha, Soonmee, Golfinos, John G., Knopp, Edmond A. and Johnson, Glyn (2003) Dynamic contrast-enhanced perfusion MR imaging measurements of endothelial permeability: differentiation between atypical and typical meningiomas. American Journal of Neuroradiology, 24 (8). pp. 1554-1559. ISSN 1936-959X

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