Items where Research Group is "Chemical Biology and Medicinal Chemistry (former - to 2021)

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Number of items: 18.

Published

Abdelhamid, Mahmoud and Waller, Zoe (2020) Tricky topology: Persistence of folded human telomeric i-motif DNA at ambient temperature and neutral pH. Frontiers in Chemistry, 8. ISSN 2296-2646

Aldholmi, Mohammed, Wilkinson, Barrie and Ganesan, A ORCID: https://orcid.org/0000-0003-4862-7999 (2020) Epigenetic modulation of secondary metabolite profiles in Aspergillus calidoustus and Aspergillus westerdijkiae through histone deacetylase (HDAC) inhibition by vorinostat. Journal of Antibiotics, 73 (6). 410–413. ISSN 0021-8820

Amparo, Camille, Clark, Jarrod, Bedell, Victoria, Murata-Collins, Joyce L., Martella, Marianna, Pichiorri, Flavia, Warner, Emily F., Abdelhamid, Mahmoud A. S., Waller, Zoë A. E. and Smith, Steven S. (2020) Duplex DNA from sites of helicase-polymerase uncoupling links non-B DNA structure formation to replicative stress. Cancer Genomics & Proteomics, 17 (2). pp. 101-115. ISSN 1109-6535

Atli, Nursabah, Harvey, James, Kay, Colin, Draijer, Richard, Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949 and O'Connell, Maria ORCID: https://orcid.org/0000-0002-0267-0951 (2020) Synthetic analogues of ferulic acidexert anti-inflammatory and antioxidanteffects in human monocytic cells. British Journal of Pharmacology, 177 (11). p. 2572. ISSN 0007-1188

Cartwright, Oliver Charles, Beekman, Andrew Michael ORCID: https://orcid.org/0000-0002-3056-6406, Cominetti, Marco M. D., Russell, David A. and Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949 (2020) A peptide-duocarmycin conjugate targeting the Thomsen-Friedenreich antigen has potent and selective antitumour activity. Bioconjugate Chemistry, 31 (7). 1745–1749. ISSN 1043-1802

Coutinho Carneiro, Vitor, de Abreu da Silva, Isabel Caetano, Amaral, Murilo Sena, Pereira, Adriana S.A., Silveira, Gilbert Oliveira, Pires, David da Silva, Verjovski-Almeida, Sergio, Dekker, Frank J., Rotili, Dante, Mai, Antonello, Lopes-Torres, Eduardo José, Robaa, Dina, Sippl, Wolfgang, Pierce, Raymond J., Borrello, M. Teresa, Ganesan, A. ORCID: https://orcid.org/0000-0003-4862-7999, Lancelot, Julien, Thiengo, Silvana, Fernandez, Monica Ammon, Vicentino, Amanda Roberta Revoredo, Mourão, Marina Moraes, Coelho, Fernanda Sales and Fantappié, Marcelo Rosado (2020) Pharmacological inhibition of lysine-specific demethylase 1 (LSD1) induces global transcriptional deregulation and ultrastructural alterations that impair viability in Schistosoma mansoni. PLoS Neglected Tropical Diseases, 14 (7). ISSN 1935-2727

De Lera, Angel R. and Ganesan, A. ORCID: https://orcid.org/0000-0003-4862-7999 (2020) Two-hit wonders: The expanding universe of multitargeting epigenetic agents. Current Opinion in Chemical Biology, 57. pp. 135-154. ISSN 1367-5931

Ferreira, Glaucio Monteiro, de Magalhães, Juliana Gallottini, Maltarollo, Vinícius Gonçalves, Kronenberger, Thales, Ganesan, Arasu ORCID: https://orcid.org/0000-0003-4862-7999, Emery, Flávio Da Silva and Trossini, Gustavo Henrique Goulart (2020) QSAR studies on the human sirtuin 2 inhibition by non-covalent 7,5,2-anilinobenzamide derivatives. Journal of Biomolecular Structure and Dynamics, 38 (2). pp. 354-363. ISSN 0739-1102

Ganesan, A. ORCID: https://orcid.org/0000-0003-4862-7999 (2020) HDAC inhibitors in cancer therapy. In: Histone Modifications in Therapy. Elsevier, pp. 19-49. ISBN 9780128164228

Ganesan, A. ORCID: https://orcid.org/0000-0003-4862-7999 (2020) Targeting the Zinc-Dependent Histone Deacetylases (HDACs) for Drug Discovery. In: Topics in Medicinal Chemistry. Topics in Medicinal Chemistry . Springer, pp. 1-27. ISBN 978-3-030-42981-2

Goddard, Zoë Rachael ORCID: https://orcid.org/0000-0002-7900-1553, Marin, Maria J. ORCID: https://orcid.org/0000-0001-8021-5498, Russell, David A. and Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949 (2020) Active targeting of gold nanoparticles as cancer therapeutics. Chemical Society Reviews, 49 (23). pp. 8774-8789. ISSN 0306-0012

Ho, Terence C. S., Chan, Alex H. Y. and Ganesan, A. ORCID: https://orcid.org/0000-0003-4862-7999 (2020) Thirty years of HDAC inhibitors: 2020 hindsight. Journal of Medicinal Chemistry, 63 (21). 12460–12484. ISSN 0022-2623

Kawamura, Akane and Ganesan, A. ORCID: https://orcid.org/0000-0003-4862-7999 (2020) Editorial overview: Epigenetics equals chemical biology. Current Opinion in Chemical Biology, 57. A1-A4. ISSN 1367-5931

King, Jessica J., Irving, Kelly L., Evans, Cameron W., Chikhale, Rupesh ORCID: https://orcid.org/0000-0001-5622-3981, Becker, Rouven, Morris, Chris ORCID: https://orcid.org/0000-0002-7703-4474, Peña Martinez, Cristian D., Schofield, Peter, Christ, Daniel, Hurley, Laurence H., Waller, Zoe, Iyer, K. Swaminathan and Smith, Nicole M. (2020) DNA G-quadruplex and i-motif structure formation is interdependent in human cells. Journal of the American Chemical Society, 142 (49). 20600–20604. ISSN 0002-7863

Liang, Liyun, Wang, Haiwen, Du, Yongliang, Luo, Bingling, Meng, Ning, Cen, Meifeng, Huang, Peng, Ganesan, A. ORCID: https://orcid.org/0000-0003-4862-7999 and Wen, Shijun (2020) New tranylcypromine derivatives containing sulfonamide motif as potent LSD1 inhibitors to target acute myeloid leukemia: design, synthesis and biological evaluation. Bioorganic Chemistry, 99. ISSN 0045-2068

Ohsawa, Kosuke, Zhao, Hongbin, Tokunaga, Takuya, Thomas, Carys, Ganesan, A. ORCID: https://orcid.org/0000-0003-4862-7999, Masuda, Yuichi and Doi, Takayuki (2020) Stereoselective synthesis of protected l-allo-Enduracididine and l-Enduracididine via asymmetric nitroaldol reaction. Synthesis-Stuttgart, 52 (6). pp. 942-948. ISSN 0039-7881

Spence, Philip, Fielden, John ORCID: https://orcid.org/0000-0001-5963-7792 and Waller, Zoë. A. E. (2020) Beyond solvent exclusion: i-Motif detecting capability and an alternative DNA light-switching mechanism in a ruthenium(II) polypyridyl complex. Journal of the American Chemical Society, 142 (32). pp. 13856-13866. ISSN 0002-7863

Wright, Elisé P., Abdelhamid, Mahmoud A. S., Ehiabor, Michelle O., Grigg, Melanie C., Irving, Kelly, Smith, Nicole M. and Waller, Zoë A. E. (2020) Epigenetic modification of cytosines fine tunes the stability of i-motif DNA. Nucleic Acids Research, 48 (1). pp. 55-62. ISSN 0305-1048

This list was generated on Sat Nov 23 13:21:42 2024 UTC.