Items where Author is "Crichton, Paul"

Keipert, Susanne, Gaudry, Michael J., Kutschke, Maria, Keuper, Michaela, Dela Rosa, Margeoux A. S. ORCID: https://orcid.org/0000-0002-9586-763X, Cheng, Yiming, Monroy Kuhn, José M., Laterveer, Rutger, Cotrim, Camila A., Giere, Peter, Perocchi, Fabiana, Feederle, Regina, Crichton, Paul G. ORCID: https://orcid.org/0000-0003-3786-8359, Lutter, Dominik and Jastroch, Martin (2024) Two-stage evolution of mammalian adipose tissue thermogenesis. Science, 384 (6700). pp. 1111-1117. ISSN 0036-8075

Jones, Scott A., Ruprecht, Jonathan J., Crichton, Paul G. ORCID: https://orcid.org/0000-0003-3786-8359 and Kunji, Edmund R. S. (2024) Structural mechanisms of mitochondrial uncoupling protein 1 regulation in thermogenesis. Trends in Biochemical Sciences, 49 (6). pp. 506-519. ISSN 0968-0004

Gaudry, Michael J., Khudyakov, Jane, Pirard, Laura, Debier, Cathy, Crocker, Daniel, Crichton, Paul G. ORCID: https://orcid.org/0000-0003-3786-8359 and Jastroch, Martin (2024) Terrestrial birth and body size tune UCP1 functionality in seals. Molecular Biology and Evolution, 41 (4). ISSN 0737-4038

Jones, Scott A., Gogoi, Prerana, Ruprecht, Jonathan J., King, Martin S., Lee, Yang, Zögg, Thomas, Pardon, Els, Chand, Deepak, Steimle, Stefan, Copeman, Danielle M., Cotrim, Camila A., Steyaert, Jan, Crichton, Paul G. ORCID: https://orcid.org/0000-0003-3786-8359, Moiseenkova-Bell, Vera and Kunji, Edmund R. S. (2023) Structural basis of purine nucleotide inhibition of human uncoupling protein 1. Science Advances, 9 (22). ISSN 2375-2548

Cavalieri, Riccardo, Hazebroek, Marlou Klein, Cotrim, Camila A., Lee, Yang, Kunji, Edmund R. S., Jastroch, Martin, Keipert, Susanne and Crichton, Paul G. ORCID: https://orcid.org/0000-0003-3786-8359 (2022) Activating ligands of Uncoupling protein 1 identified by rapid membrane protein thermostability shift analysis. Molecular Metabolism, 62. ISSN 2212-8778

Ntessalen, Maria, Procter, Nathan E K, Feelisch, Martin, Crichton, Paul G ORCID: https://orcid.org/0000-0003-3786-8359 and Frenneaux, Michael P (2020) Reply to TA Schiffer et al. The American Journal of Clinical Nutrition, 111 (2). pp. 487-488. ISSN 0002-9165

Ntessalen, Maria, Procter, Nathan, Schwarz, Konstantin, Loudon, Brodie, Minnion, Magdalena, Fernandez, Bernadette, Vassiliou, Vassilios ORCID: https://orcid.org/0000-0002-4005-7752, Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756, Madhani, Melanie, Constantin‐Teodosiu, Dumitru, Horrowitz, John, Dawson, Dana, Crichton, Paul ORCID: https://orcid.org/0000-0003-3786-8359 and Frenneaux, Michael (2020) Inorganic nitrate and nitrite supplementation fails to improve skeletal muscle mitochondrial efficiency in mice and humans. The American Journal of Clinical Nutrition, 111 (1). pp. 79-89. ISSN 0002-9165

Ruprecht, Jonathan J., King, Martin S., Zögg, Thomas, Aleksandrova, Antoniya A., Pardon, Els, Crichton, Paul G. ORCID: https://orcid.org/0000-0003-3786-8359, Steyaert, Jan and Kunji, Edmund R. S. (2019) The molecular mechanism of transport by the mitochondrial ADP/ATP carrier. Cell, 176 (3). 435-447.e15. ISSN 0092-8674

King, Martin S., Crichton, Paul G. ORCID: https://orcid.org/0000-0003-3786-8359, Ruprecht, Jonathan J. and Kunji, Edmund R. S. (2018) Correspondence: Concerns with yeast mitochondrial ADP/ATP carrier’s integrity in DPC. Nature Structural & Molecular Biology, 25. 747–749. ISSN 1545-9993

Springett, Roger, King, Martin S, Crichton, Paul G ORCID: https://orcid.org/0000-0003-3786-8359 and Kunji, Edmund R S (2017) Modelling the free energy profile of the mitochondrial ADP/ATP carrier. Biochimica et Biophysica Acta, 1858 (11). pp. 906-914. ISSN 0006-3002

Harborne, Steven P D, King, Martin S, Crichton, Paul G ORCID: https://orcid.org/0000-0003-3786-8359 and Kunji, Edmund R S (2017) Calcium regulation of the human mitochondrial ATP-Mg/Pi carrier SLC25A24 uses a locking pin mechanism. Scientific Reports, 7. ISSN 2045-2322

Crichton, Paul G. ORCID: https://orcid.org/0000-0003-3786-8359, Lee, Yang and Kunji, Edmund R. S. (2017) The molecular features of uncoupling protein 1 support a conventional mitochondrial carrier-like mechanism. Biochimie, 134. 35–50. ISSN 0300-9084

Kunji, Edmund R.S., Aleksandrova, Antoniya, King, Martin S., Majd, Homa, Ashton, Valerie L., Cerson, Elizabeth, Springett, Roger, Kibalchenko, Mikhail, Tavoulari, Sotiria, Crichton, Paul G. ORCID: https://orcid.org/0000-0003-3786-8359 and Ruprecht, Jonathan J. (2016) The transport mechanism of the mitochondrial ADP/ATP carrier. Biochimica Et Biophysica Acta-Molecular Cell Research, 1863 (10). pp. 2379-2393. ISSN 0167-4889

King, Martin S., Kerr, Matthew, Crichton, Paul G. ORCID: https://orcid.org/0000-0003-3786-8359, Springett, Roger and Kunji, Edmund R.S. (2016) Formation of a cytoplasmic salt bridge network in the matrix state is a fundamental step in the transport mechanism of the mitochondrial ADP/ATP carrier. Biochimica Et Biophysica Acta-Bioenergetics, 1857 (1). pp. 14-22. ISSN 0005-2728

Lee, Yang, Willers, Chrissie, Kunji, Edmund R S and Crichton, Paul G. ORCID: https://orcid.org/0000-0003-3786-8359 (2015) Uncoupling protein 1 binds one nucleotide per monomer and is stabilized by tightly bound cardiolipin. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 112 (22). pp. 6973-6978. ISSN 0027-8424

Crichton, Paul G. ORCID: https://orcid.org/0000-0003-3786-8359, Lee, Yang, Ruprecht, Jonathan J., Cerson, Elizabeth, Thangaratnarajah, Chancievan, King, Martin S. and Kunji, Edmund R. S. (2015) Trends in thermostability provide information on the nature of substrate, inhibitor, and lipid interactions with mitochondrial carriers. Journal of Biological Chemistry, 290 (13). pp. 8206-8217. ISSN 0021-9258

Ruprecht, Jonathan J., Hellawell, Alex M., Harding, Marilyn, Crichton, Paul G. ORCID: https://orcid.org/0000-0003-3786-8359, McCoy, Airlie J. and Kunji, Edmund R. S. (2014) Structures of yeast mitochondrial ADP/ATP carriers support a domain-based alternating-access transport mechanism. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 111 (4). E426–E434. ISSN 0027-8424

Crichton, Paul G. ORCID: https://orcid.org/0000-0003-3786-8359, Harding, Marilyn, Ruprecht, Jonathan J., Lee, Yang and Kunji, Edmund R. S. (2013) Lipid, detergent, and coomassie blue G-250 affect the migration of small membrane proteins in blue native gels:Mitochondrial carriers migrate as monomers not dimers. Journal of Biological Chemistry, 288 (30). pp. 22163-22173. ISSN 0021-9258

Oelkrug, Rebecca, Goetze, Nadja, Exner, Cornelia, Lee, Yang, Ganjam, Goutham K., Kutschke, Maria, Müller, Saskia, Stöhr, Sigrid, Tschöp, Matthias H., Crichton, Paul G. ORCID: https://orcid.org/0000-0003-3786-8359, Heldmaier, Gerhard, Jastroch, Martin and Meyer, Carola W. (2013) Brown fat in a protoendothermic mammal fuels eutherian evolution. Nature Communications, 4. ISSN 2041-1723

Crichton, Paul G. ORCID: https://orcid.org/0000-0003-3786-8359, Parker, Nadeene, Vidal-Puig, Antonio J. and Brand, Martin D. (2010) Not all mitochondrial carrier proteins support permeability transition pore formation: no involvement of uncoupling protein 1. Bioscience Reports, 30 (3). pp. 187-192. ISSN 0144-8463

Crichton, Paul G. ORCID: https://orcid.org/0000-0003-3786-8359, Albury, Mary S., Affourtit, Charles and Moore, Anthony L. (2010) Mutagenesis of the Sauromatum guttatum alternative oxidase reveals features important for oxygen binding and catalysis. Biochimica Et Biophysica Acta-Bioenergetics, 1797 (6-7). pp. 732-737. ISSN 0005-2728

Kunji, Edmund R. S. and Crichton, Paul G. ORCID: https://orcid.org/0000-0003-3786-8359 (2010) Mitochondrial carriers function as monomers. Biochimica Et Biophysica Acta-Bioenergetics, 1797 (6-7). pp. 817-831. ISSN 0005-2728

Parker, Nadeene, Crichton, Paul G. ORCID: https://orcid.org/0000-0003-3786-8359, Vidal-Puig, Antonio J. and Brand, Martin D. (2009) Uncoupling protein-1 (UCP1) contributes to the basal proton conductance of brown adipose tissue mitochondria. Journal of Bioenergetics and Biomembranes, 41. ISSN 0145-479X

Moore, Anthony L., Carré, Jane E., Affourtit, Charles, Albury, Mary S., Crichton, Paul G. ORCID: https://orcid.org/0000-0003-3786-8359, Kita, Kiyoshi and Heathcote, Peter (2008) Compelling EPR evidence that the alternative oxidase is a diiron carboxylate protein. Biochimica Et Biophysica Acta-Bioenergetics, 1777 (4). pp. 327-330. ISSN 0005-2728

Affourtit, Charles, Crichton, Paul G. ORCID: https://orcid.org/0000-0003-3786-8359, Parker, Nadeene and Brand, Martin D. (2007) Novel Uncoupling Proteins. In: Mitochondrial Biology: New Perspectives. Novartis Foundation Symposia, 287 . Wiley, pp. 70-80. ISBN 9780470066577

Crichton, Paul G. ORCID: https://orcid.org/0000-0003-3786-8359, Affourtit, Charles and Moore, Anthony L. (2007) Identification of a mitochondrial alcohol dehydrogenase in Schizosaccharomyces pombe: new insights into energy metabolism. Biochemical Journal, 401 (2). pp. 459-464. ISSN 0264-6021

Moore, Anthony L., Albury, Mary S. and Crichton, Paul G. ORCID: https://orcid.org/0000-0003-3786-8359 (2006) ‘Green’ …yet wasting energy? - mitochondrial respiration in plants. The Biochemist, 28 (4). pp. 13-16. ISSN 0954-982X

Crichton, Paul G. ORCID: https://orcid.org/0000-0003-3786-8359, Affourtit, Charles, Albury, Mary S., Carré, Jane E. and Moore, Anthony L. (2005) Constitutive activity of Sauromatum guttatum alternative oxidase in Schizosaccharomyces pombe implicates residues in addition to conserved cysteines in α-keto acid activation. FEBS Letters, 579 (2). pp. 331-336. ISSN 0014-5793

Moore, Anthony L., Albury, Mary S., Crichton, Paul G. ORCID: https://orcid.org/0000-0003-3786-8359 and Affourtit, Charles (2002) Function of the alternative oxidase:Is it still a scavenger? Trends in Plant Science, 7 (11). pp. 478-481. ISSN 1360-1385

Affourtit, Charles, Albury, Mary S., Crichton, Paul G. ORCID: https://orcid.org/0000-0003-3786-8359 and Moore, Anthony L. (2002) Exploring the molecular nature of alternative oxidase regulation and catalysis. FEBS Letters, 510 (3). pp. 121-126. ISSN 0014-5793

Albury, Mary S., Affourtit, Charles, Crichton, Paul G. ORCID: https://orcid.org/0000-0003-3786-8359 and Moore, Anthony L. (2002) Structure of the plant alternative oxidase:Site-directed mutagenesis provides new information on the active site and membrane topology. Journal of Biological Chemistry, 277. pp. 1190-1194. ISSN 0021-9258