Items where Research Group is "Synthetic and Medicinal Chemistry

Published

Alhunayhin, Sultanah M. N., Bushby, Richard J., Cammidge, Andrew N. and Samman, Saeed S. (2024) Triphenylene discotic liquid crystals: Biphenyls, synthesis, and the search for nematic systems. Liquid Crystals, 51 (8-9). pp. 1333-1344. ISSN 0267-8292

Almatari, Altaf S., Saeed, Ali, Abdel-Ghani, Ghada E., Abdullah, Mahmood M. S., Al-Lohedan, Hamad A., Abdel-Latif, Ehab and El-Demerdash, Amr (2024) Synthesis of some novel thiophene analogues as potential anticancer agents. Chemistry and Biodiversity, 21 (7). ISSN 1612-1872

Almatari, Altaf S., Saeed, Ali, Abdel-Ghani, Ghada E., Abdullah, Mahmood M. S., El-Demerdash, Amr and Abdel-Latif, Ehab (2024) Employing acetoacetamide as a key synthon for synthesizing novel thiophene derivatives and assessing their potential as antioxidants and antimicrobial agents. Journal of Heterocyclic Chemistry, 61 (7). pp. 1075-1090. ISSN 0022-152X

Alshammari, Muteb H., Alhunayhin, Sultanah M. N., Hughes, David L., Chambrier, Isabelle and Cammidge, Andrew N. (2024) Scramble-free synthesis of unhindered trans-A2B2-mesoaryl porphyrins via bromophenyl dipyrromethanes. Organic Letters, 26 (8). pp. 1561-1565. ISSN 1523-7060

Aly, Omnia, Mekky, Reham Hassan, Pereira, Florbela, Diab, Yasser M., Tammam, Mohamed A. and El-Demerdash, Amr (2024) Deciphering the potential of Cymbopogon citratus (DC.) Stapf as an anti-obesity agent: phytochemical profiling, in vivo evaluations and molecular docking studies. Food & Function, 15 (24). pp. 12146-12168. ISSN 2042-6496

Bertolini, Marco, Mendive-Tapia, Lorena, Ghashghaei, Ouldouz, Reese, Abigail, Lochenie, Charles, Schoepf, Anna M., Sintes, Miquel, Tokarczyk, Karolina, Nare, Zandile, Scott, Andrew D., Knight, Stephen R., Aithal, Advait R., Sachdeva, Amit, Lavilla, Rodolfo and Vendrell, Marc (2024) Nonperturbative fluorogenic labeling of immunophilins enables the wash-free detection of immunosuppressants. ACS Central Science, 10 (5). 969–977. ISSN 2374-7943

Bew, Sean, Sue, Xiao-Song, Cai, Liu and Tan, Hao-Dong (2024) Halogen cation transfer in halogen bonding catalysis.

Carroll, Joseph J., Sprigg, Colleen, Chilvers, Graham, Delso, Ignacio, Barker, Megan, Cox, Filipa, Johnson, David and Brearley, Charles A. (2024) LC-ICP-MS analysis of inositol phosphate isomers in soil offers improved sensitivity and fine‐scale mapping of inositol phosphate distribution. Methods in Ecology and Evolution, 15 (3). pp. 530-543. ISSN 2041-210X

Cominetti, Marco M. D., Goddard, Zoë R., Hood, Bethany R., Beekman, Andrew M., O'Connell, Maria A. and Searcey, Mark (2024) Borylation via iridium catalysed C–H activation: a new concise route to duocarmycin derivatives. Organic & Biomolecular Chemistry, 22 (27). pp. 5603-5607. ISSN 1477-0520

Compañón, Ismael, Ballard, Collin J., Lira-Navarrete, Erandi, Santos, Tanausú, Monaco, Serena, Muñoz-García, Juan C., Delso, Ignacio, Angulo, Jesus, Gerken, Thomas A., Schjoldager, Katrine T., Clausen, Henrik, Tejero, Tomás, Merino, Pedro, Corzana, Francisco, Hurtado-Guerrero, Ramon and Ghirardello, Mattia (2024) Rational design of dual-domain binding inhibitors for N-acetylgalactosamine transferase 2 with improved selectivity over the T1 and T3 isoforms. JACS Au, 4 (9). pp. 3649-3656. ISSN 2691-3704

Dedola, Simone, Ahmadipour, Sanaz, de Andrade, Peterson, Baker, Alexander N., Boshra, Andrew N., Chessa, Simona, Gibson, Matthew I., Hernando, Pedro J., Ivanova, Irina M., Lloyd, Jessica E., Marin, Maria J., Munro-Clark, Alexandra J., Pergolizzi, Giulia, Richards, Sarah-Jane, Ttofi, Iakovia, Wagstaff, Ben A. and Field, Robert (2024) Sialic acids in infection and their potential use in detection and protection against pathogens. RSC Chemical Biology, 5 (3). pp. 167-188. ISSN 2633-0679

Delso, Ignacio (2024) Investigating hydrophobic eutectic systems from the NMR perspective. In: 20th European Magnetic Resonance Conference, 2024-06-30 - 2024-07-04.

Esfahani, Mohammadreza Haftbaradaran, Bergua, Fernando, Delso, Ignacio, Lafuente, Carlos and Artal, Manuela (2024) Geraniol and hydrophobic geraniol:thymol eutectic mixtures: Structure and thermophysical characterization. Industrial Crops & Products, 222 (Part 3). ISSN 0926-6690

Goddard, Zoë R., Searcey, Mark and Osbourn, Anne (2024) Advances in triterpene drug discovery. Trends in Pharmacological Sciences, 45 (11). pp. 964-968. ISSN 0165-6147

Hamshaw, Isabel, Cominetti, Marco, Nana-Akyin, Princess, Ho Yee Ho, Ernie, Searcey, Mark and Mueller, Anja (2024) IS4-FAM, a fluorescent tool to study CXCR4 affinity and competitive antagonism in native cancer cells. Pharmacology Research and Perspectives, 12 (5). ISSN 2052-1707

Hayward, Deanne and Beekman, Andrew M. (2024) Strategies for converting turn-motif and cyclic peptides to small molecules for targeting protein–protein interactions. RSC Chemical Biology, 5 (3). pp. 198-208. ISSN 2633-0679

Hayward, Deanne, Goddard, Zoë R., Cominetti, Marco M. D., Searcey, Mark and Beekman, Andrew M. (2024) Light-activated azobenzene peptide inhibitor of the PD-1/PD-L1 interaction. Chemical Communications, 60 (63). pp. 8228-8231. ISSN 1359-7345

Hodgson, Hannah, Stephenson, Michael J., Kikuchi, Shingo, Martin, Laetitia B. B., Liu, Jack C. T., Casson, Rebecca, Rejzek, Martin, Sattely, Elizabeth S. and Osbourn, Anne (2024) Plants utilize a protection/deprotection strategy in limonoid biosynthesis: A “missing link” carboxylesterase boosts yields and provides insights into furan formation. Journal of the American Chemical Society, 146 (43). pp. 29305-29310. ISSN 0002-7863

Ibrahim, Rana M., Fayez, Shaimaa, Eltanany, Basma M., Abu-Elghait, Mohammed, El-Demerdash, Amr, Badawy, Mona Shaban E. M., Pont, Laura, Benavente, Fernando and Saber, Fatema R. (2024) Agro-byproduct valorization of radish and turnip leaves and roots as new sources of antibacterial and antivirulence agents through metabolomics and molecular networking. Scientia Horticulturae, 328. ISSN 0304-4238

Kuperman, Ofir Aharon, de Andrade, Peterson, Sui, Xiao Meng, Maria, Raquel, Kaplan-Ashiri, Ifat, Jiang, Qixiang, Terlier, Tanguy, Kirkensgaard, Jacob Judas Kain, Field, Robert A. and Natalio, Filipe (2024) Harnessing precursor-directed biosynthesis with glucose derivatives to access cotton fibers with enhanced physical properties. Cell Reports Physical Science, 5 (5). ISSN 2666-3864

Kuperman, Ofir Aharon, de Andrade, Peterson, Terlier, Tanguy, Kirkensgaard, Jacob Judas Kain, Field, Robert A. and Natalio, Filipe (2024) The effect of a low degree of fluorine substitution on cotton fiber properties. Macromolecular Materials and Engineering, 309 (3). ISSN 1438-7492

Liu, Yuzhong, Zhao, Xixi, Gan, Fei, Chen, Xiaoyue, Deng, Kai, Crowe, Samantha A., Hudson, Graham A., Belcher, Michael S., Schmidt, Matthias, Astolfi, Maria C. T., Kosina, Suzanne M., Pang, Bo, Shao, Minglong, Yin, Jing, Sirirungruang, Sasilada, Iavarone, Anthony T., Reed, James, Martin, Laetitia B. B., El-Demerdash, Amr, Kikuchi, Shingo, Misra, Rajesh Chandra, Liang, Xiaomeng, Cronce, Michael J., Chen, Xiulai, Zhan, Chunjun, Kakumanu, Ramu, Baidoo, Edward E. K., Chen, Yan, Petzold, Christopher J., Northen, Trent R., Osbourn, Anne, Scheller, Henrik and Keasling, Jay D. (2024) Complete biosynthesis of QS-21 in engineered yeast. Nature, 629 (8013). pp. 937-944. ISSN 0028-0836

Lockwood, Colin W. J., Nash, Benjamin W., Newton-Payne, Simone E., van Wonderen, Jessica H., Whiting, Keir P. S., Connolly, Abigail, Sutton-Cook, Alexander L., Crook, Archie, Aithal, Advait R., Edwards, Marcus J., Clarke, Thomas A., Sachdeva, Amit and Butt, Julea N. (2024) Genetic code expansion in Shewanella oneidensis MR-1 allows site-specific incorporation of bioorthogonal functional groups into a c-type Cytochrome. ACS Synthetic Biology, 13 (9). pp. 2833-2843. ISSN 2161-5063

Martin, Laetitia B.B., Kikuchi, Shingo, Rejzek, Martin, Owen, Charlotte, Reed, James, Orme, Anastasia, Misra, Rajesh C., El-Demerdash, Amr, Hill, Lionel, Hodgson, Hannah, Liu, Yuzhong, Keasling, Jay D., Field, Robert A., Truman, Andrew W. and Osbourn, Anne (2024) Complete biosynthesis of the potent vaccine adjuvant QS-21. Nature Chemical Biology, 20 (4). pp. 493-502. ISSN 1552-4450

Padilla, Nuria, Delso, Ignacio, Bergua, Fernando and Lafuente, Carlos (2024) Characterization of camphor:thymol or dl-menthol eutectic mixtures; Structure, thermophysical properties and lidocaine solubility. Journal of Molecular Liquids, 405. ISSN 0167-7322

Reese, Abigail E., de Moliner, Fabio, Mendive-Tapia, Lorena, Benson, Sam, Kuru, Erkin, Bridge, Thomas, Richards, Josh, Rittichier, Jonathan, Kitamura, Takanori, Sachdeva, Amit, McSorley, Henry J. and Vendrell, Marc (2024) Inserting “OFF-to-ON” BODIPY tags into cytokines: A fluorogenic interleukin IL-33 for real-time imaging of immune cells. ACS Central Science, 10 (1). 143–154. ISSN 2374-7951

Saeed, Ali, Soliman, Ahbarah M., Abdullah, Mahmood M. S., Abdel-Latif, Ehab and El-Demerdash, Amr (2024) Synthesis and molecular docking of some new thiazolidinone and thiadiazole derivatives as anticancer agents. Chemistry and Biodiversity, 21 (7). ISSN 1612-1872

Steverding, Dietmar, Tinson, Ryan A. J., Piras, Monica, Wren, Stephen P., Rushworth, Stuart A., Searcey, Mark and Troeberg, Linda (2024) Suramin: Effectiveness of analogues reveals structural features that are important for the potent trypanocidal activity of the drug. Experimental Parasitology, 260. ISSN 0014-4894

Tammam, Mohamed A., Aly, Omnia, Pereira, Florbela, Mahdy, Aldoushy and El-Demerdash, Amr (2024) Unveiling the potential of marine-derived diterpenes from the order Alcyonacea as promising anti-obesity agents. Current Research in Biotechnology, 7. ISSN 2590-2628

Tammam, Mohamed A., Gamal El-Din, Mariam I., Aouidate, Adnane and El-Demerdash, Amr (2024) Cephalostatins and ritterazines: Distinctive dimeric marine-derived steroidal pyrazine alkaloids with intriguing anticancer activities. Bioorganic Chemistry, 151. ISSN 0045-2068

Wahart, Alice J. C., Beardmore, Liam N. D., Field, Robert A., Cosgrove, Sebastian C. and Miller, Gavin J. (2024) Tandem one-pot biocatalytic oxidation and Wittig reaction in water. Organic Letters, 26 (31). pp. 6642-6646. ISSN 1523-7060

Yeung, Andy Wai Kan, Solka, Magdalena, Jóźwik, Artur, Ksepka, Natalia, Matin, Maima, Wang, Dongdong, Zielińska, Aleksandra, Mohanasundaram, Arunsundar, Vejux, Anne, Zarrouk, Amira, Tewari, Devesh, Horbańczuk, Jarosław Olav, Lucarini, Massimo, Durazzo, Alessandra, Ghzaiel, Imen, Michalczuk, Monika, Rezig, Leila, Tzvetkov, Nikolay T., Matin, Farhan Bin, Lizard, Gérard, Bishayee, Anupam, Devkota, Hari Prasad, El-Demerdash, Amr, Brnčić, Mladen, Santini, Antonello, Mickael, Michel-Edwar, Horbańczuk, Olaf, Charuta, Anna, Szafrańska, Karina, Małachowska, Ewa, Wieczorek, Marek, Siddiquea, Bodrun Naher, Hrg, Dalibor, Frazzini, Sara, Rossi, Luciana, Singla, Rajeev K., Wieczorek, Anna, Łysek-Gładysinska, Małgorzata, Chandragiri, Siva Sai, Adamska, Olga, Stolarczyk, Artur, Klusek, Justyna, Szymańska-Czerwińska, Monika, Niemczuk, Krzysztof, Hejna, Monika, Sztandarski, Patryk, Jaszczyk, Aneta, Michnowska, Hanna, Tomasik, Cyprian, Zima-Kulisiewicz, Bogumila, Marchewka, Joanna, Ławiński, Michał and Atanasov, Atanas G. (2024) Anthocyanins-dietary natural products with a variety of bioactivities for the promotion of human and animal health. Animal Science Papers and Reports, 42 (1). pp. 5-33. ISSN 0860-4037

Zhang, Rui-Bin, Grunwald, Marco A., Zeng, Xiang-Bing, Laschat, Sabine, Cammidge, Andrew N. and Ungar, Goran (2024) Orientational transitions of discotic columnar liquid crystals in cylindrical pores. Soft Matter, 20 (31). pp. 6193-6203. ISSN 1744-683X