Items where Research Group is "Synthetic and Medicinal Chemistry

Bew, Sean P., Hughes, David L., Palmer, Nicholas J., Savic, Vladimir, Soapi, Katy M. and Wilson, Martin A. (2006) Stereoselective synthesis of N-alkylaziridines from N-chloroamines. Chemical Communications (41). pp. 4338-4340. ISSN 1359-7345

Bew, Sean P., Hughes, David L., Savic, Vladimir, Soapi, Katy M. and Wilson, Martin A. (2006) Expedient synthesis of substituted (S)-N-(α-methylbenzyl)aziridines. Chemical Communications (33). pp. 3513-3515. ISSN 1359-7345

Bew, Sean P., Hughes, David L. and Sharma, Sunil (2006) Acid-catalyzed synthesis of methylene-bridged (S)-tyrosine−phenol dimers. Journal of Organic Chemistry, 71 (20). pp. 7881-7884. ISSN 0022-3263

Borner, Ruth C., Boden, N, Bushby, Richard J., Cammidge, Andrew N. and Jesudason, M. V. (2006) Ferric chloride/methanol in the preparation of triphenylene-based discotic liquid crystals:The synthesis of triphenylene‐based discotic mesogens New and improved routes. Liquid Crystals, 33 (11-12). pp. 1439-1448. ISSN 0267-8292

Cammidge, Andrew N. (2006) The effect of size and shape variation in discotic liquid crystals based on triphenylene cores. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 364 (1847). 2697–2708. ISSN 1364-503X

Cammidge, Andrew N., Goddard, Victoria H. M., Gopee, Hemant, Harrison, Nicola L., Hughes, David L., Schubert, Christopher J., Sutton, Benjamin M., Watts, Gary L. and Whitehead, Andrew J. (2006) Aryl trihydroxyborates: Easily isolated discrete species convenient for direct application in coupling reactions. Organic Letters, 8 (18). pp. 4071-4074. ISSN 1523-7052

Cammidge, Andrew N. and Gopee, Hemant (2006) Perylenophthalocyanines. Chemistry - A European Journal, 12. pp. 8609-8613. ISSN 0947-6539

Cammidge, Andrew N. and King, Amy S. H. (2006) Model studies towards liquid crystalline dendrimers with mesogenic repeat units throughout the structure. Tetrahedron Letters, 47 (31). pp. 5569-5572.

David-Cordonnier, Marie‐Hélène, Casely-Hayford, Maxwell, Kouach, Mostafa, Briand, Gilbert, Patterson, Laurence H., Bailly, Christian and Searcey, Mark (2006) Stereoselectivity, sequence specificity and mechanism of action of the azinomycin epoxide. ChemBioChem, 7 (11). 1658–1661. ISSN 1439-4227

Germain, A. R., Porco, J. A., Searcey, M. and Woon, E. (2006) Studies towards the synthesis of the p53-MDM2 inhibitor chlorofusin. Abstracts of Papers of the American Chemical Society, 231. 449-ORGN. ISSN 0065-7727

Guino, M., Patterson, L. H. and Searcey, M. (2006) ORGN 741-Total synthesis of duocarmycin prodrugs. Abstracts of Papers of the American Chemical Society, 232. 741-ORGN. ISSN 0065-7727

Hamilton, Chris J., Saravanamuthu, Ahilan, Poupat, Christiane, Fairlamb, Alan H. and Eggleston, Ian M. (2006) Time-dependent inhibitors of trypanothione reductase: Analogues of the spermidine alkaloid lunarine and related natural products. Bioorganic & Medicinal Chemistry, 14 (7). pp. 2266-2278. ISSN 0968-0896

Hannant, Mark H., Wright, Joseph A., Lancaster, Simon J., Hughes, David L., Horton, Peter N. and Bochmann, Manfred (2006) The synthesis of new weakly coordinating diborate anions: anion stability as a function of linker structure and steric bulk. Dalton Transactions (20). pp. 2415-2426. ISSN 1477-9234

Hopcroft, N. H., Brogden, A. L., Searcey, M. and Cardin, C. J. (2006) X-ray crystallographic study of DNA duplex cross-linking: simultaneous binding to two d(CGTACG)(2) molecules by a bis(9-aminoacridine-4-carboxamide) derivative. Nucleic Acids Research, 34 (22). pp. 6663-6672. ISSN 0305-1048

Howard, RH, Bochmann, M and Wright, JA (2006) {Bis(3,5-Di-tert-butyl-2-oxidobenzyl)[2-(N,N-dimethylamino)ethyl]amine-κ4N,N',O ,O'}zinc(II) and {bis(3-tert-butyl-5-methyl-2-oxidobenzyl)[2-(N ,N-dimethylamino)ethyl]amine-κ4N,N',O,O'}(tetrahdyrofuran)zinc(II). Acta Crystallographica Section C, 62 (7). m293-m296. ISSN 1600-5759

Moore, Michael J. B., Cuenca, Francisco, Searcey, Mark and Neidle, Stephen (2006) Synthesis of distamycin A polyamides targeting G-quadruplex DNA. Organic & Biomolecular Chemistry, 4 (18). pp. 3479-3488. ISSN 1477-0520

Paumier, D., Malkinson, J. P., Hampshire, A. J., Fox, K. R. and Searcey, M. (2006) ORGN 223-Solid phase-supported synthesis of a water-soluble TANDEM analog. Abstracts of Papers of the American Chemical Society, 232. ISSN 0065-7727

Pors, Klaus, Shnyder, Steven D., Teesdale-Spittle, Paul H., Hartley, John A., Zloh, Mire, Searcey, Mark and Patterson, Laurence H. (2006) Synthesis of DNA-directed pyrrolidinyl and piperidinyl confined alkylating chloroalkylaminoanthraquinones: Potential for development of tumor-selective N-oxides. Journal of Medicinal Chemistry, 49 (24). pp. 7013-7023. ISSN 0022-2623

Pugh, David, Wright, Joseph A., Freeman, Sandra and Danopoulos, Andreas A. (2006) ‘Pincer’ dicarbene complexes of some early transition metals and uranium. Dalton Transactions (6). pp. 775-782. ISSN 1477-9226

Rowan, Andrew S. and Hamilton, Chris J. (2006) Recent developments in preparative enzymatic syntheses of carbohydrates. Natural Product Reports, 23 (3). pp. 412-443. ISSN 0265-0568

Sarazin, Yann, Wright, Joseph A. and Bochmann, Manfred (2006) Synthesis and crystal structure of [C6H5Hg(H2NSiMe3)][H2N{B(C6F5)3}2], a phenyl–mercury(II) cation stabilised by a non-coordinating counter-anion. Journal of Organometallic Chemistry, 691 (26). pp. 5680-5687.

Tsoukala, G., Falconer, R. A. and Searcey, M. (2006) ORGN 731-Toward the total synthesis of Ipomoeassin B. Abstracts of Papers of the American Chemical Society, 232. 731-ORGN. ISSN 0065-7727

Williams, Robert, Searcey, Mark and Potter, Barry (2006) Cancer treatments for the new millennium. Drug News & Perspectives, 19 (4). pp. 229-232. ISSN 0214-0934

Wilson, Polly A., Hannant, Mark H., Wright, Joseph A., Cannon, Roderick D. and Bochmann, Manfred (2006) Anion influence in metallocene-based olefin polymerisation catalysts. Macromolecular Symposia, 236 (1). pp. 100-110. ISSN 1022-1360

Woon, E. C. Y. and Searcey, M. (2006) ORGN 224-Analogs of chlorofusin as potential inhibitors of p53/MDM2 interaction. Abstracts of Papers of the American Chemical Society, 232. 224-ORGN. ISSN 0065-7727

Wright, Joseph A., Danopoulos, Andreas A., Motherwell, William B., Carroll, Robert J. and Ellwood, Simon (2006) ‘Pincer’ pyridyl- and bipyridyl-N-heterocyclic carbene analogues of the Grubbs’ metathesis catalyst. Journal of Organometallic Chemistry, 691 (24-25). pp. 5204-5210.

Wright, Joseph A., Danopoulos, Andreas A., Motherwell, William B., Carroll, Robert J., Ellwood, Simon and Saßmannshausen, Jorg (2006) “Pincer” N-heterocyclic carbene complexes of rhodium functionalised with pyridyl and bipyridyl donors. European Journal of Inorganic Chemistry, 2006 (23). pp. 4857-4865. ISSN 1099-0682

Wright, Jospeh A., Gaunt, Matthew J. and Spencer, Jonathan B. (2006) Novel anti-Markovnikov regioselectivity in the Wacker reaction of styrenes. Chemistry - A European Journal, 12 (3). pp. 949-955. ISSN 0947-6539