Items where Research Group is "Cancer Studies

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Number of items: 40.


Bao, Y ORCID: (2005) Bioactivities of dietary isothiocyanates. Agro Food Industry Hi Tech, 16 (3). pp. 24-26.

Bao, Y ORCID: (2005) Phytochemicals and Human Health - Bioactivity of dietary isothiocyanates. In: SMI Nutraceuticals and Functional Foods Conference, London, UK, 2005-01-01.

Bao, Y ORCID:, Jakubikova, J and Sedlák, J (2005) MAPK and P13K signalling pathways in isothiocyanate-induced gene expression, G2 /M arrest and cell death. In: American Association of Cancer Research meeting, 2005-01-01.

Bao, Y ORCID:, Jakubikova, J, Sedlák, J, Bacon, J and Mithen, R (2005) MAPK and P13K signaling pathways in isothiocyanates-induced gene expression, G2/M arrest and apoptosis. Proceedings of the American Association of Cancer Research, 46 (1). p. 565.


Carrivick, L., Rogers, S., Clark, J., Campbell, C., Girolami, M. and Cooper, C. ORCID: (2005) Identification of prognostic signatures in breast cancer microarray data using Bayesian techniques. Journal of The Royal Society Interface, 3 (8). pp. 367-381. ISSN 1742-5689

Chen, Keli, Plumb, Geoff W., Bennett, Richard N. and Bao, Yongping ORCID: (2005) Antioxidant activities of extracts from five anti-viral medicinal plants. Journal of Ethnopharmacology, 96 (1-2). pp. 201-205.


Davies, Helen, Hunter, Chris, Smith, Raffaella, Stephens, Philip, Greenman, Christopher, Bignell, Graham, Teague, Jon, Butler, Adam, Edkins, Sarah, Stevens, Claire, Parker, Adrian, O'Meara, Sarah, Avis, Tim, Barthorpe, Syd, Brackenbury, Lisa, Buck, Gemma, Clements, Jody, Cole, Jennifer, Dicks, Ed, Edwards, Ken, Forbes, Simon, Gorton, Matthew, Gray, Kristian, Halliday, Kelly, Harrison, Rachel, Hills, Katy, Hinton, Jonathon, Jones, David, Kosmidou, Vivienne, Laman, Ross, Lugg, Richard, Menzies, Andrew, Perry, Janet, Petty, Robert, Raine, Keiran, Shepherd, Rebecca, Small, Alexandra, Solomon, Helen, Stephens, Yvonne, Tofts, Calli, Varian, Jennifer, Webb, Anthony, West, Sofie, Widaa, Sara, Yates, Andrew, Brasseur, Francis, Cooper, Colin S ORCID:, Flanagan, Adrienne M, Green, Anthony, Knowles, Maggie, Leung, Suet Y, Looijenga, Leendert H J, Malkowicz, Bruce, Pierotti, Marco A, Teh, Bin T, Yuen, Siu T, Lakhani, Sunil R, Easton, Douglas F, Weber, Barbara L, Goldstraw, Peter, Nicholson, Andrew G, Wooster, Richard, Stratton, Michael R and Futreal, P Andrew (2005) Somatic mutations of the protein kinase gene family in human lung cancer. Cancer Research, 65 (17). pp. 7591-5. ISSN 0008-5472

Denton, Christopher P., Lindahl, Gisela E., Khan, Korsa, Xu, Shiwen, Ong, Voon H., Gaspar, Nicholas J., Lazaridis, Konstantinos, Edwards, Dylan R. ORCID:, Leask, Andrew, Eastwood, Mark, Leoni, Patricia, Renzoni, Elisabetta A., Gharios, George Bou, Abraham, David J. and Black, Carol M. (2005) Activation of key profibrotic mechanisms in transgenic fibroblasts expressing kinase-deficient type II transforming growth factor-beta receptor (T beta RII Delta k). Journal of Biological Chemistry, 280. pp. 16053-16065. ISSN 1083-351X


Elkington, Paul T. G., Nuttall, Robert K., Boyle, Joseph J., O'Kane, Cecilia M., Horncastle, Donna E., Edwards, Dylan R. ORCID: and Friedland, Jon S. (2005) Mycobacterium tuberculosis, but not vaccine BCG, specifically upregulates matrix metalloproteinase-1. American Journal of Respiratory and Critical Care Medicine, 172 (12). pp. 1596-1604. ISSN 1535-4970


Ge, Yulin, Law, Meng, Johnson, Glyn, Herbert, Joseph, Babb, James S., Mannon, Lois J. and Grossman, Robert I. (2005) Dynamic susceptibility contrast perfusion MR imaging of multiple sclerosis lesions: characterizing hemodynamic impairment and inflammatory activity. American Journal of Neuroradiology, 26 (6). pp. 1539-1547. ISSN 1936-959X

Gukas, Isaac D., Jennings, Barbara A. ORCID:, Leinster, Samuel J. and Harvey, Ian (2005) A theme issue by, for, and about Africa: Collaborative work between Nigeria and UK on breast cancer has been successful. British Medical Journal, 331 (7519). ISSN 0959-8138


Handsley, M.M. ORCID: and Edwards, D.R. ORCID: (2005) Metalloproteinases and their inhibitors in tumour angiogenesis. International Journal of Cancer, 115. pp. 849-860.


Inglese, Matilde, Makani, Sachin, Johnson, Glyn, Cohen, Benjamin A., Silver, Jonathan A., Gonen, Oded and Grossman, Robert I. (2005) Diffuse axonal injury in mild traumatic brain injury: a diffusion tensor imaging study. Journal of Neurosurgery, 103 (2). 298-303.. ISSN 0022-3085


Jakubikova, Jana, Bao, Yongping ORCID: and Sedlák, Jan (2005) Isothiocyanates induce cell cycle arrest, apoptosis and mitochondrial potential depolarization in HL-60 and multidrug-resistant cell lines. Anticancer Research, 25 (5). pp. 3375-3386. ISSN 1791-7530

Jakubikova, Jana, Sedlák, Ján, Bacon, James, Goldson, Andrew and Bao, Yongping ORCID: (2005) Effects of MEK1 and PI3K inhibitors on allyl-, benzyl- and phenylethyl-isothiocyanate-induced G2/M arrest and cell death in Caco-2 cells. International Journal of Oncology, 27 (5). pp. 1449-1458.

Jakubíková, Jana, Sedlák, Ján, Mithen, Richard and Bao, Yongping ORCID: (2005) Role of PI3K/Akt and MEK/ERK signaling pathways in sulforaphane - and erucin- induced phase II enzymes and MRP2 transcription, G2/M arrest and cell death in Caco-2 cells. Biochemical Pharmacology, 69 (11). pp. 1543-1552.

Jennings, BA ORCID:, Bardsley, V, Lonsdale, R, Fellows, I, Wimperis, J, Willis, G, Bingham, SA and Khaw, KT (2005) The penetrance of HFE C282Y mutations with respect to hepatocellular carcinoma is low in a UK population. American Journal of Ooentgenology American Journal of Roentgenology, 131. p. 342.

Jhavar, S., Corbishley, C. M., Dearnaley, D., Fisher, C., Falconer, A., Parker, C., Eeles, R. and Cooper, C. S. ORCID: (2005) Construction of tissue microarrays from prostate needle biopsy specimens. British Journal of Cancer, 93 (4). pp. 478-482. ISSN 0007-0920


Kassiri, Zamaneh, Oudit, Gavin Y., Sanchez, Otto, Dawood, Fayez, Mohammed, Fazilat F., Nuttall, Robert K., Edwards, Dylan R. ORCID:, Liu, Peter P., Backx, Peter H. and Khokha, Rama (2005) Combination of tumor necrosis factor-α ablation and matrix metalloproteinase inhibition prevents heart failure after pressure overload in tissue inhibitor of metalloproteinase-3 knock-out mice. Circulation Research, 97. pp. 380-390.


Lu, Hanzhang, Law, Meng, Johnson, Glyn, Ge, Yulin, van Zijl, Peter C. M. and Helpern, Joseph A. (2005) Novel approach to the measurement of absolute cerebral blood volume using vascular-space-occupancy magnetic resonance imaging. Magnetic Resonance in Medicine, 54 (6). pp. 1403-1411. ISSN 0740-3194

Lui, Yvonne W., Nusbaum, Annette O., Barr, William B., Johnson, Glyn, Babb, James S., Orbach, Darren, Kim, Alice, Laliotis, Georgia and Devinsky, Orrin (2005) Correlation of apparent diffusion coefficient with neuropsychological testing in temporal lobe epilepsy. American Journal of Neuroradiology, 26 (7). pp. 1832-1839. ISSN 1936-959X


McIntyre, Alan, Summersgill, Brenda, Grygalewicz, Beata, Gillis, Ad J. M., Stoop, J., van Gurp, Ruud J. H. L. M., Dennis, Nening, Fisher, Cyril, Huddart, Robert, Cooper, Colin ORCID:, Clark, Jeremy, Oosterhuis, J. Wolter, Looijenga, Leendert H. J. and Shipley, Janet (2005) Amplification and overexpression of the KIT gene is associated with progression in the seminoma subtype of testicular germ cell tumors of adolescents and adults. Cancer Research, 65 (18). pp. 8085-8089. ISSN 0008-5472

Mohammed, Fazilat F., Pennington, Caroline J., Kassiri, Zamaneh, Rubin, Jeffrey S., Soloway, Paul D., Ruther, Ulrich, Edwards, Dylan R. ORCID: and Khokha, Rama (2005) Metalloproteinase inhibitor TIMP-1 affects hepatocyte cell cycle via HGF activation in murine liver regeneration. Hepatology, 41 (4). pp. 857-867. ISSN 1527-3350


O'Connell, Maria ORCID:, Ogborne, Richard M., Rushworth, Stuart, Harvey, Glynn and Schipper, J (2005) Effect of dietary antioxidants on glutamate cysteine ligse modulator sub-unit gene expression in human THP-1 cells. In: Proceedings of the Nutrition Society. UNSPECIFIED, 67A.

Ogborne, R. M., Rushworth, S. A. and O'Connell, M. A. ORCID: (2005) alpha-lipoic acid-induced heme oxygenase-1 expression is mediated by nuclear factor erythroid 2-related factor 2 and p38 mitogen-activated protein kinase in human monocytic cells. Arteriosclerosis, Thrombosis, and Vascular Biology, 25 (10). pp. 2100-2105. ISSN 1079-5642

Olsson, A Yvonne and Cooper, Colin S ORCID: (2005) The molecular basis of prostate cancer. British Journal of Hospital Medicine, 66 (11). pp. 612-6. ISSN 1750-8460


Pedersen, Tanja Xenia, Pennington, Caroline J., Almhold, Kasper, Christensen, Ib Jarle, Nielsen, Boye Schnack, Edwards, Dylan R. ORCID:, Rømer, John, Danø, Keld and Johnsen, Morten (2005) Extracellular protease mRNAs are predominantly expressed in the stromal areas of microdissected mouse breast carcinomas. Carcinogenesis, 26. pp. 1233-1240. ISSN 1460-2180

Perani, Michela, Antonson, Per, Hamoudi, Rifat, Ingram, Catherine J E, Cooper, Colin S ORCID:, Garrett, Michelle D and Goodwin, Graham H (2005) The proto-oncoprotein SYT interacts with SYT-interacting protein/co-activator activator (SIP/CoAA), a human nuclear receptor co-activator with similarity to EWS and TLS/FUS family of proteins. Journal of Biological Chemistry, 280 (52). pp. 42863-76. ISSN 0021-9258

Porter, Sarah, Clark, Ian M., Kevorkian, Lara and Edwards, Dylan R. ORCID: (2005) The ADAMTS metalloproteinases. Biochemical Journal, 386 (1). pp. 15-27.


Riddick, A.C., Shukla, C.J., Pennington, C.J., Bass, R., Nuttall, R.K., Hogan, A., Sethia, K.K., Ellis, V., Collins, A.T., Maitland, N.J., Ball, R.Y. and Edwards, D.R. ORCID: (2005) Identification of degradome components associated with prostate cancer progression by expression analysis of human prostatic tissues. British Journal of Cancer, 92 (12). pp. 2171-2180. ISSN 0007-0920

Rushworth, Stuart A., Chen, Xi-Lin, Mackman, Nigel, Ogborne, Richard M. and O'Connell, Maria A. ORCID: (2005) Lipopolysaccharide-induced heme oxygenase-1 expression in human monocytic cells is mediated via Nrf2 and protein kinase C. Journal of Immunology, 175 (7). pp. 4408-4415. ISSN 0022-1767


Singh, Robert J. R., Mason, Justin C., Lidington, Elaine A., Edwards, Dylan R. ORCID:, Nuttall, Robert K., Khokha, Rama, Knauper, Vera, Murphy, Gillian and Gavrilovic, Jelena ORCID: (2005) Cytokine stimulated vascular cell adhesion molecule-1 (VCAM-1) ectodomain release is regulated by TIMP-3. Cardiovascular Research, 67 (1). pp. 39-49. ISSN 0008-6363

Stephens, Philip, Edkins, Sarah, Davies, Helen, Greenman, Christopher, Cox, Charles, Hunter, Chris, Bignell, Graham, Teague, Jon, Smith, Raffaella, Stevens, Claire, O'Meara, Sarah, Parker, Adrian, Tarpey, Patrick, Avis, Tim, Barthorpe, Andy, Brackenbury, Lisa, Buck, Gemma, Butler, Adam, Clements, Jody, Cole, Jennifer, Dicks, Ed, Edwards, Ken, Forbes, Simon, Gorton, Matthew, Gray, Kristian, Halliday, Kelly, Harrison, Rachel, Hills, Katy, Hinton, Jonathon, Jones, David, Kosmidou, Vivienne, Laman, Ross, Lugg, Richard, Menzies, Andrew, Perry, Janet, Petty, Robert, Raine, Keiran, Shepherd, Rebecca, Small, Alexandra, Solomon, Helen, Stephens, Yvonne, Tofts, Calli, Varian, Jennifer, Webb, Anthony, West, Sofie, Widaa, Sara, Yates, Andrew, Brasseur, Francis, Cooper, Colin S ORCID:, Flanagan, Adrienne M, Green, Anthony, Knowles, Maggie, Leung, Suet Y, Looijenga, Leendert H J, Malkowicz, Bruce, Pierotti, Marco A, Teh, Bin, Yuen, Siu T, Nicholson, Andrew G, Lakhani, Sunil, Easton, Douglas F, Weber, Barbara L, Stratton, Michael R, Futreal, P Andrew and Wooster, Richard (2005) A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer. Nature Genetics, 37 (6). pp. 590-592. ISSN 1061-4036


Traka, Maria, Gasper, Amy V., Smith, Julie A., Hawkey, Chris J., Bao, Yongping ORCID: and Mithen, Richard F. (2005) Transcriptome analysis of human colon Caco-2 cells exposed to sulforaphane. Journal of Nutrition, 135 (8). pp. 1865-1872. ISSN 1541-6100


Wang, Wei, Wang, Shuran A., Howie, A. Forbes, Beckett, Geoffrey J., Mithen, Richard and Bao, Yongping ORCID: (2005) Sulforaphane, erucin and iberin up-regulate thioredoxin reductase 1 expression in human MCF-7 cells. Journal of Agricultural and Food Chemistry, 53 (5). pp. 1417-1421. ISSN 1520-5118

Weaver, Andrew, Goncalves da Silva, Angelika, Nuttall, Robert K., Edwards, Dylan R. ORCID:, Shapiro, Steven D., Rivest, Serge and Young, V. Wee (2005) An elevated matrix metalloproteinase (MMP) in an animal model of multiple sclerosis is protective by affecting Th1/Th2 polarization. FASEB Journal, 19 (12). pp. 1668-1670.

Willis, G, Uddin, M, Finglas, P, Wright, A, Clarke, S, Smilth, K, Heron, D and Jennings, BA ORCID: (2005) A study of multiple polymorphisms of folate-dependent one-carbon metabolism in a northern European population. European Journal of Human Genetics, 13 (1). p. 348. ISSN 1476-5438

Willis, Gavin, Bardsley, Vicky, Fellows, Ian W., Lonsdale, Roy, Wimperis, Jennie Z. and Jennings, Barbara A. ORCID: (2005) Hepatocellular carcinoma and the penetrance of HFE C282Y mutations: a cross sectional study. BMC Gastroenterology, 5. ISSN 1471-230X


Young, David A., Billingham, Olivia, Sampieri, Clara L., Edwards, Dylan R. ORCID: and Clark, Ian M. (2005) Differential effects of histone deacetylase inhibitors on phorbol ester- and TGF-beta 1 induced murine tissue inhibitor of metalloproteinases-1 gene expression. FEBS Journal, 272 (8). pp. 1912-1926. ISSN 1742-4658

Young, David A., Lakey, Rachel L., Pennington, Caroline J., Jones, Debra, Kevorkian, Lara, Edwards, Dylan R. ORCID:, Cawston, Timothy E. and Clark, Ian M. (2005) Histone deacetylase inhibitors modulate metalloproteinase gene expression in chondrocytes and block cartilage resorption. Arthritis Research & Therapy, 7 (3). pp. 503-512. ISSN 1478-6354

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