Items where Research Group is "Pharmacology and Biological Chemistry

A

Atkinson, Sarah H., Rockett, Kirk A., Morgan, Gareth, Bejon, Philip A., Sirugo, Giorgio, O'Connell, Maria, Hanchard, Neil, Kwiatkowski, Dominic P. and Prentice, Andrew M. (2008) Tumor necrosis factor SNP haplotypes are associated with iron deficiency anemia in West African children. Blood, 112 (10). pp. 4276-4283. ISSN 0006-4971

B

Basran, Jaswir, Rafice, Sara A., Chauhan, Nishma, Efimov, Igor, Cheesman, Myles R., Ghamsari, Lila and Raven, Emma Lloyd (2008) A kinetic, spectroscopic, and redox study of human tryptophan 2,3-dioxygenase. Biochemistry, 47 (16). pp. 4752-4760. ISSN 0006-2960

Bew, Sean P., Cheesman, Myles R. and Sharma, Sunil V. (2008) Ferrocenium salts mediate para-tert-butylcalixarene synthesis. Chemical Communications (44). pp. 5731-5733. ISSN 1359-7345

C

Clarke, Thomas A., Kemp, Gemma L., Van Wonderen, Jessica H., Doyle, Rosie-Marie A. S., Cole, Jeffrey A., Tovell, Nick, Cheesman, Myles R., Butt, Julea N., Richardson, David J. and Hemmings, Andrew M. (2008) Role of a conserved gluatmine residue in tuning the catalytic activity of Escherichia coli cytochrome c nitrite reductase. Biochemistry, 47 (12). pp. 3789-3799.

Clarke, Thomas A., Mills, Paul C., Poock, Susie R., Butt, Julea N., Cheesman, Myles R., Cole, Jeffrey A., Hinton, Jay C. D., Hemmings, Andrew M., Kemp, Gemma, Söderberg, Christopher A. G., Spiro, Stephen, van Wonderen, Jessica and Richardson, David J. (2008) Escherichia coli cytochrome c nitrite reductase NrfA. Methods in Enzymology, 437. pp. 63-77. ISSN 1557-7988

Crack, Jason C., Gaskell, Alisa A., Green, Jeffrey, Cheesman, Myles R., Le Brun, Nick E. and Thomson, Andrew J. (2008) Influence of the environment on the [4Fe−4S]2+ to [2Fe−2S]2+ cluster switch in the transcriptional regulator FNR. Journal of the American Chemical Society, 130 (5). pp. 1749-1758. ISSN 1520-5126

Crack, Jason C., Jervis, Adrian J., Gaskell, Alice, White, Gaye F., Green, Jeffrey, Thomson, Andrew J. and Le Brun, Nick E. (2008) Signal perception by FNR: the role of the iron–sulfur cluster. Biochemical Society Transactions, 36 (6). 1144–1148. ISSN 0300-5127

Crack, Jason C., Le Brun, Nick E., Thomson, Andrew J., Green, Jeffrey and Jervis, Adrian J. (2008) Reactions of nitric oxide and oxygen with the regulator of fumarate and nitrate reduction, a global transcriptional regulator, during anaerobic growth of Escherichia coli. Methods in Enzymology, 437. pp. 191-209. ISSN 1557-7988

H

Hodson, Christopher T. C., Lewin, Allison, Hederstedt, Lars and Le Brun, Nick E. (2008) The active-site cysteinyls and hydrophobic cavity residues of ResA are important for cytochrome c maturation in Bacillus subtilis. Journal of Bacteriology, 190 (13). pp. 4697-4705. ISSN 1098-5530

K

Kihlken, Margaret A., Singleton, Chloe and Le Brun, Nick E. (2008) Distinct characteristics of Ag+ and Cd2+ binding to CopZ from Bacillus subtilis. JBIC Journal of Biological Inorganic Chemistry, 13 (6). pp. 1011-1023. ISSN 0949-8257

L

Lalor, Ruth, Baillie-Johnson, Hugo, Redshaw, Carl, Matthews, Susan E. and Mueller, Anja (2008) Cellular uptake of a fluorescent calix[4]arene derivative. Journal of the American Chemical Society, 130 (10). pp. 2892-2893. ISSN 1520-5126

Lee, Hannah Y. Y., Morton, James D., Sanderson, Julie, Bickerstaffe, Roy and Robertson, Lucinda J. G. (2008) The involvement of calpains in opacification induced by Ca2+-overload in ovine lens culture. Veterinary Ophthalmology, 11 (6). pp. 347-355. ISSN 1463-5224

Lewin, Allison, Crow, Allister, Hodson, Christopher T. C., Hederstedt, Lars and Le Brun, Nick E. (2008) Effects of substitutions in the CXXC active-site motif of the extracytoplasmic thioredoxin ResA. Biochemical Journal, 414 (1). 81–91. ISSN 0264-6021

M

Marritt, Sophie J., Kemp, Gemma L., Xiaoe, Li, Durrant, James R., Cheesman, Myles R. and Butt, Julea N. (2008) Spectroelectrochemical characterization of a pentaheme cytochrome in solution and as electrocatalytically active films on nanocrystalline metal-oxide electrodes. Journal of the American Chemical Society, 130 (27). pp. 8588-8589. ISSN 1520-5126

McLean, Kirsty J., Carroll, Paul, Lewis, D. Geraint, Dunford, Adrian J., Seward, Harriet E., Neeli, Rajasekhar, Cheesman, Myles R., Marsollier, Laurent, Douglas, Philip, Smith, W. Ewen, Rosenkrands, Ida, Cole, Stewart T., Leys, David, Parish, Tanya and Munro, Andrew W. (2008) Characterization of active site structure in CYP121: A cytochrome P450 essential for viability of mycobacterium tuberculosis H37Rv. Journal of Biological Chemistry, 283 (48). pp. 33406-33416. ISSN 0021-9258

Meiser, Andrea, Mueller, Anja, Wise, Emma L., McDonagh, Ellen M., Petit, Sarah J., Saran, Namita, Clark, Peter C., Williams, Timothy J. and Pease, James E. (2008) The chemokine receptor CXCR3 is degraded following internalization and is replenished at the cell surface by de novo synthesis of receptor. Journal of Immunology, 180 (10). pp. 6713-6724. ISSN 0022-1767

Moyano Cardaba, Clara, Kerr, Jason S. and Mueller, Anja (2008) CCR5 internalisation and signalling have different dependence on membrane lipid raft integrity. Cellular Signalling, 20 (9). pp. 1687-1694.

Mueller, Anja, Meiser, Andrea, McDonagh, Ellen M., Fox, James M., Petit, Sarah J., Xanthou, Georgina, Williams, Timothy J. and Pease, James E. (2008) CXCL4-induced migration of activated T lymphocytes is mediated by the chemokine receptor CXCR3. Journal of Leukocyte Biology, 83 (4). pp. 875-882. ISSN 0741-5400

O

O'Connell, Maria and Rushworth, Stuart (2008) Curcumin: potential for hepatic fibrosis therapy? British Journal of Pharmacology, 153 (3). pp. 403-405. ISSN 1476-5381

Ogborne, Richard M., Rushworth, Stuart and O'Connell, Maria (2008) Epigallocatechin activates haem oxygenase-1 expression via protein kinase Cδ and Nrf2. Biochemical and Biophysical Research Communications, 373 (4). pp. 584-588. ISSN 1090-2104

R

Rushworth, Stuart A., MacEwan, David J. and O'Connell, Maria A. (2008) Lipopolysaccharide-induced expression of NAD(P)H:quinone oxidoreductase 1 and heme oxygenase-1 protects against excessive inflammatory responses in human monocytes. Journal of Immunology, 181 (10). pp. 6730-6737. ISSN 0022-1767

S

Singleton, Chloe, Banci, Lucia, Ciofi-Baffoni, Simone, Tenori, Leonardo, Kihlken, Margaret A., Boetzel, Ruth and Le Brun, Nick E. (2008) Structure and Cu(I)-binding properties of the N-terminal soluble domains of Bacillus subtilis CopA. Biochemical Journal, 411 (3). 571–579. ISSN 0264-6021

Sobolewski, Anastasia, Rudarakanchana, Nung, Upton, Paul D., Yang, Jun, Crilley, Trina K., Trembath, Richard C. and Morrell, Nicholas W. (2008) Failure of bone morphogenetic protein receptor trafficking in pulmonary arterial hypertension: potential for rescue. Human Molecular Genetics, 17 (20). pp. 3180-3190. ISSN 0964-6906

T

Tovell, Victoria and Sanderson, Julie (2008) Distinct P2Y receptor subtypes regulate calcium signaling in human retinal pigment epithelial cells. Investigative Ophthalmology & Visual Science, 49 (1). pp. 350-357. ISSN 0146-0404

Tucker, Nicholas P., Hicks, Matthew G., Clarke, Thomas A., Crack, Jason C., Chandra, Govind, Le Brun, Nick E., Dixon, Ray and Hutchings, Matthew I. (2008) The transcriptional repressor protein NsrR senses nitric oxide directly via a [2Fe-2S] cluster. PLoS One, 3 (11). ISSN 1932-6203

V

van Wonderen, Jessica H., Burlat, Bénédicte, Richardson, David J., Cheesman, Myles R. and Butt, Julea N. (2008) The nitric oxide reductase activity of cytochrome c nitrite reductase from Escherichia coli. Journal of Biological Chemistry, 283 (15). pp. 9587-9594. ISSN 1083-351X

Y

Yang, Jun, Davies, Rachel J., Southwood, Mark, Long, Lu, Yang, Xudong, Sobolewski, Anastasia, Upton, Paul D., Trembath, Richard C. and Morrell, Nicholas W. (2008) Mutations in bone morphogenetic protein Type II receptor cause dysregulation of Id gene expression in pulmonary artery smooth muscle cells: Implications for familial pulmonary arterial hypertension. Circulation Research, 102 (10). pp. 1212-1221. ISSN 0009-7330

Z

Zhou, Liang, Singleton, Chloe and Le Brun, Nick E. (2008) High Cu(I) and low proton affinities of the CXXC motif of Bacillus subtilis CopZ. Biochemical Journal, 413 (3). 459–465. ISSN 0264-6021