Items where Research Group is "Medicinal Chemistry (former - to 2017)

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Number of items: 16.

Article

Benelkebir, Hanae, Donlevy, Alison M., Packham, Graham and Ganesan, A. ORCID: https://orcid.org/0000-0003-4862-7999 (2011) Total synthesis and stereochemical assignment of burkholdac B, a depsipeptide HDAC inhibitor. Organic Letters, 13 (24). pp. 6334-6337. ISSN 1523-7060

Benelkebir, Hanae, Hodgkinson, Christopher, Duriez, Patrick J., Hayden, Annette L., Bulleid, Rosemary A., Crabb, Simon J., Packham, Graham and Ganesan, A ORCID: https://orcid.org/0000-0003-4862-7999 (2011) Enantioselective synthesis of tranylcypromine analogues as lysine demethylase (LSD1) inhibitors. Bioorganic & Medicinal Chemistry, 19 (12). pp. 3709-3716.

Benelkebir, Hanae, Marie, Sabrina, Hayden, Annette L., Lyle, Jason, Loadman, Paul M., Crabb, Simon J., Packham, Graham and Ganesan, A ORCID: https://orcid.org/0000-0003-4862-7999 (2011) Total synthesis of largazole and analogues: HDAC inhibition, antiproliferative activity and metabolic stability. Bioorganic & Medicinal Chemistry, 19 (12). pp. 3650-3658.

Bouthenet, Elise, Oh, Ki-Bong, Park, Seungil, Nagi, Navjeet K., Lee, Hyi-Seung and Matthews, Susan E. ORCID: https://orcid.org/0000-0001-8821-0851 (2011) Synthesis and antimicrobial activity of brominated resorcinol dimers. Bioorganic & Medicinal Chemistry Letters, 23 (23). pp. 7142-7145. ISSN 1464-3405

Dash, Jyotirmayee, Waller, Zoe A. E., Pantoş, G. Dan and Balasubramanian, Shankar (2011) Synthesis and binding studies of novel diethynyl-pyridine amides with genomic promoter DNA G-quadruplexes. Chemistry - A European Journal, 17 (16). 4571–4581. ISSN 0947-6539

Howe, J. D., Payerne, E., Woon, E. C. Y., Marfo, S. A., Searcey, M. ORCID: https://orcid.org/0000-0003-2273-8949 and Gavrilovic, J. (2011) Screening novel small molecules for effects on cancer cell migration. International Journal of Experimental Pathology, 92 (3). A27. ISSN 0959-9673

Howell, Lesley A., Waller, Zoe A. E., Bowater, Richard ORCID: https://orcid.org/0000-0002-2745-7807, O'Connell, Maria ORCID: https://orcid.org/0000-0002-0267-0951 and Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949 (2011) A small molecule that induces assembly of a four way DNA junction at low temperature. Chemical Communications, 47 (29). pp. 8262-8264. ISSN 1359-7345

Izumi, Minoru, Kido, Takeshi, Murakami, Miyu, Nakajima, Shuhei and Ganesan, A ORCID: https://orcid.org/0000-0003-4862-7999 (2011) Pictet-Spengler reaction using ion-exchange resin as a catalyst and support for ‘catch and release’ purification. Bioscience, Biotechnology, and Biochemistry, 75 (2). pp. 391-392. ISSN 0916-8451

McLuckie, Keith I. E., Waller, Z.A.E., Sanders, Deborah A., Alves, David, Rodriguez, Raphaël, Dash, Jyotirmayee, McKenzie, Grahame J., Venkitaraman, Ashok R. and Balasubramanian, Shankar (2011) G-Quadruplex-binding benzo[a]phenoxazines down-regulate c-KIT expression in human gastric carcinoma cells. Journal of the American Chemical Society, 133 (8). pp. 2658-2663.

Mueller, Anja ORCID: https://orcid.org/0000-0003-0774-0434, Lalor, Ruth, Moyano Cardaba, Clara and Matthews, Susan E. ORCID: https://orcid.org/0000-0001-8821-0851 (2011) Stable and sensitive probes for lysosomes: Cell-penetrating fluorescent calix[4]arenes accumulate in acidic vesicles. Cytometry Part A, 79A (2). pp. 126-136. ISSN 1552-4922

Pors, Klaus, Loadman, Paul M., Shnyder, Steven D., Sutherland, Mark, Sheldrake, Helen M., Guino, Meritxell, Kiakos, Konstantinos, Hartley, John A., Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949 and Patterson, Laurence H. (2011) Modification of the duocarmycin pharmacophore enables CYP1A1 targeting for biological activity. Chemical Communications, 47 (44). pp. 12062-12064. ISSN 1359-7345

Sharma, Sunil V., Jothivasan, Vishnu K., Newton, Gerald L., Upton, Heather, Wakabayashi, Judy I., Kane, Melissa G., Roberts, Alexandra A., Rawat, Mamta, La Clair, James J. and Hamilton, Chris J. (2011) Chemical and chemoenzymatic syntheses of bacillithiol, a unique low molecular weight thiol amongst low G + C Gram positive bacteria. Angewandte Chemie International Edition, 50 (31). pp. 7101-7104. ISSN 1433-7851

Sicard, Delphine, Cecioni, Samy, Iazykov, Maksym, Chevolot, Yann, Matthews, Susan E. ORCID: https://orcid.org/0000-0001-8821-0851, Praly, Jean-Pierre, Souteyrand, Eliane, Imberty, Anne, Vidal, Sébastien and Phaner-Goutorbe, Magali (2011) AFM investigation of Pseudomonas aeruginosa lectin LecA (PA-IL) filaments induced by multivalent glycoclusters. Chemical Communications, 47 (33). pp. 9483-9485. ISSN 1359-7345

Soomro, Zahid H., Cecioni, Samy, Blanchard, Helen, Praly, Jean-Pierre, Imberty, Anne, Vidal, Sébastien and Matthews, Susan E. ORCID: https://orcid.org/0000-0001-8821-0851 (2011) CuAAC synthesis of resorcin[4]arene-based glycoclusters as multivalent ligands of lectins. Organic & Biomolecular Chemistry, 9 (19). pp. 6587-6597. ISSN 1477-0520

Tiffon, C. E., Adams, J. E., van der Fits, L., Wen, S., Townsend, P. A., Ganesan, A. ORCID: https://orcid.org/0000-0003-4862-7999, Hodges, E., Vermeer, M. H. and Packham, G. (2011) The histone deacetylase inhibitors vorinostat and romidepsin downmodulate IL-10 expression in cutaneous T-cell lymphoma cells. British Journal of Pharmacology, 162 (7). pp. 1590-1602. ISSN 1476-5381

Williams, Paula M., Sheldrake, Gary N., Macdonald, Simon J. F. and Hamilton, Chris J. (2011) A chemoenzymatic synthesis of 5a-carba-α-d-mannose-6-phosphate. Carbohydrate Research, 346 (10). pp. 1257-1261. ISSN 1873-426X

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