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Sicard, Delphine, Cecioni, Samy, Iazykov, Maksym, Chevolot, Yann, Matthews, Susan E. 
ORCID: https://orcid.org/0000-0001-8821-0851, Praly, Jean-Pierre, Souteyrand, Eliane, Imberty, Anne, Vidal, Sébastien and Phaner-Goutorbe, Magali
(2011)
AFM investigation of Pseudomonas aeruginosa lectin LecA (PA-IL) filaments induced by multivalent glycoclusters.
Chemical Communications, 47 (33).
pp. 9483-9485.
ISSN 1359-7345
Abstract
Atomic force microscopy reveals that Pseudomonas aeruginosa LecA (PA-IL) and a tetra-galactosylated 1,3-alternate calix[4]arene-based glycocluster self-assemble according to an aggregative chelate binding mode to create monodimensional filaments. Lectin oligomers are identified along the filaments and defects in chelate binding generate branches and bifurcations. A molecular model with alternate 90° orientation of LecA tetramers is proposed to describe the organisation of lectins and glycoclusters in the filaments.
| Item Type: | Article |
|---|---|
| Faculty \ School: | Faculty of Science > School of Pharmacy |
| Depositing User: | Users 2731 not found. |
| Date Deposited: | 12 Oct 2011 10:13 |
| Last Modified: | 23 Oct 2022 01:03 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/34990 |
| DOI: | 10.1039/C1CC13097H |
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