Items where Author is "Bidula, Stefan"

Article

Ahire, Jayshree, Wang, Qi, Bao, Yongping ORCID: https://orcid.org/0000-0002-6425-0370, Storer, Isabelle ORCID: https://orcid.org/0000-0001-8717-2574, Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138, Rowley, Gary ORCID: https://orcid.org/0000-0002-5421-4333 and Crack, Jason (2026) Heparin-Conjugated Silver Nanoparticles via Amide Chemistry for Selective Targeting of Triple-Negative Breast Cancer and Pathogenic Fungi. International Journal of Nanomedicine, 21 (21). ISSN 1176-9114

Middleton, Georgie, Mahamud, Fuad O., Storer, Isabelle S. R. ORCID: https://orcid.org/0000-0001-8717-2574, Williams-Gunn, Abigail, Wostear, Finn, Abdolrasouli, Alireza, Barclay, Elaine, Bradford, Alice, Steward, Oliver ORCID: https://orcid.org/0009-0002-2854-2787, Schelenz, Silke, McColl, James, Lézé, Bertrand, van Rhijn, Norman, da Silva Dantas, Alessandra, Furukawa, Takanori, Warren, Derek, Waller, Zoë A. E. and Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138 (2025) Evidence that G-quadruplexes form in pathogenic fungi and represent promising antifungal targets. EMBO Molecular Medicine, 17 (12). 3636–3656. ISSN 1757-4676

Tammam, Mohamed A., Pereira, Florbela, Skellam, Elizabeth, Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138, Ganesan, A. and El-Demerdash, Amr ORCID: https://orcid.org/0000-0001-6459-2955 (2025) The cytochalasans: Potent fungal natural products with application from bench to bedside. Natural Product Reports, 42 (5). pp. 788-841. ISSN 0265-0568

Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138, Piyasirananda, Waraporn, Bielecka, Hanna, Bibič, Lučka, Beekman, Andrew ORCID: https://orcid.org/0000-0002-3056-6406 and Stokes, Leanne ORCID: https://orcid.org/0000-0003-4013-6781 (2025) Screening herbal and natural product libraries to aid discovery of novel allosteric modulators of human P2X7. Purinergic Signalling, 21 (2). 365–379. ISSN 1573-9538

Johnson, Robert T., Wostear, Finn, Solanki, Reesha, Steward, Oliver, Bradford, Alice, Morris, Christopher, Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138 and Warren, Derek T. (2024) A microtubule stability switch alters isolated vascular smooth muscle Ca2+ flux in response to matrix rigidity. Journal of Cell Science, 137 (21). ISSN 0021-9533

Johnson, Robert T., Solanki, Reesha, Wostear, Finn, Ahmed, Sultan, Taylor, James C. K., Rees, Jasmine, Abel, Geraad, McColl, James, Jørgensen, Helle F., Morris, Chris J., Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138 and Warren, Derek T. (2024) Piezo1-mediated regulation of smooth muscle cell volume in response to enhanced extracellular matrix rigidity. British Journal of Pharmacology, 181 (11). pp. 1576-1595. ISSN 0007-1188

Porubiaková, Otília, Havlík, Jan, Indu, Šedý, Michal, Přepechalová, Veronika, Bartas, Martin, Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138, Šťastný, Jiří, Fojta, Miroslav and Brázda, Václav (2023) Variability of inverted repeats in all available genomes of bacteria. Microbiology Spectrum, 11 (4). ISSN 2165-0497

Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138 and Brázda, Václav (2023) Genomic analysis of non-B nucleic acids structures in SARS-CoV-2: Potential key roles for these structures in mutability, translation, and replication? Genes, 14 (1). ISSN 2073-4425

Dobrovolná, Michaela, Brázda, Václav, Warner, Emily F. and Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138 (2022) Inverted repeats in the monkeypox virus genome are hot spots for mutation. Journal of Medical Virology, 95 (1). ISSN 0146-6615

Bohálová, Natália, Dobrovolná, Michaela, Brázda, Václav and Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138 (2022) Conservation and over-representation of G-quadruplex sequences in regulatory regions of mitochondrial DNA across distinct taxonomic sub-groups. Biochimie, 194. pp. 28-34. ISSN 0300-9084

Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138, Nadzirin, Izzuddin Bin, Cominetti, Marco, Hickey, Harry, Cullum, Sean A., Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949, Schmid, Ralf and Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548 (2022) Structural basis of the negative allosteric modulation of 5-BDBD at human P2X4 receptors. Molecular Pharmacology, 101 (1). pp. 33-44. ISSN 1521-0111

Stokes, Leanne ORCID: https://orcid.org/0000-0003-4013-6781, Bielecka, Hanna, Felgate, Matthew, Beekman, Andrew ORCID: https://orcid.org/0000-0002-3056-6406, Ngameni, Bathelemy, Chi, Godloves Fru, Stephenson, Richard and Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138 (2021) Dioscin-related glycosides as positive allosteric modulators of P2X7 receptors. British Journal of Pharmacology, 178 (24). p. 4947. ISSN 0007-1188

Ghandhi, Laura H. D., Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138, Pask, Christopher M., Lord, Rianne M. ORCID: https://orcid.org/0000-0001-9981-129X and McGowan, Patrick C. (2021) Bis(N-picolinamido)cobalt(II) complexes display antifungal activity toward Candida albicans and Aspergillus fumigatus. ChemMedChem, 16 (20). pp. 3210-3221. ISSN 1860-7179

Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138 (2021) Analysis of putative G-quadruplex forming sequences in inflammatory mediators and their potential as targets for treating inflammatory disorders. Cytokine, 142. ISSN 1043-4666

Warner, Emily F., Bohálová, Natália, Brázda, Václav, Waller, Zoë A. E. and Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138 (2021) Analysis of putative quadruplex-forming sequences in fungal genomes: Novel antifungal targets? Microbial Genomics, 7 (5). ISSN 2057-5858

Piyasirananda, Waraporn, Beekman, Andrew ORCID: https://orcid.org/0000-0002-3056-6406, Ganesan, A., Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138 and Stokes, Leanne ORCID: https://orcid.org/0000-0003-4013-6781 (2021) Insights into the structure-activity relationship of glycosides as positive allosteric modulators acting on P2X7 receptors. Molecular Pharmacology, 99 (2). pp. 163-174. ISSN 0026-895X

Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138, Bibic, Lucka, Moulton, Adrienne, Zhang, Jiayi and Stokes, Leanne ORCID: https://orcid.org/0000-0003-4013-6781 (2020) Revisiting the past to enhance the future:Traditional medicinal plant extracts in the discovery of novel drug lead to target P2X7. British Journal of Pharmacology, 177 (11). pp. 2628-2629. ISSN 0007-1188

Stokes, Leanne ORCID: https://orcid.org/0000-0003-4013-6781, Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138, Bibič, Lučka and Allum, Elizabeth (2020) To inhibit or enhance? Is there a benefit to positive allosteric modulation of P2X receptors? Frontiers in Pharmacology, 11. ISSN 1663-9812

Bidula, S. ORCID: https://orcid.org/0000-0002-3790-7138, Dhuna, K., Helliwell, R., Stebbing, M. and Stokes, L. ORCID: https://orcid.org/0000-0003-4013-6781 (2019) Herbaceous homicide:The Panax ginseng metabolite compound K accelerates caspase-3/7 activation and enhances macrophage cell death in a P2X7-dependent manner. British Journal of Pharmacology, 176 (16). p. 3028. ISSN 0007-1188

Bidula, Stefan M. ORCID: https://orcid.org/0000-0002-3790-7138, Cromer, Brett A., Walpole, Samuel, Angulo, Jesus ORCID: https://orcid.org/0000-0001-7250-5639 and Stokes, Leanne ORCID: https://orcid.org/0000-0003-4013-6781 (2019) Mapping a novel positive allosteric modulator binding site in the central vestibule region of human P2X7. Scientific Reports, 9. ISSN 2045-2322

Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138, Sexton, Darren and Schelenz, Silke (2019) Ficolins and the recognition of pathogenic microorganisms: An overview of the innate immune response and contribution of single nucleotide polymorphisms. Journal of Immunology Research, 2019. ISSN 2314-7156

Dhuna, Kshitija, Felgate, Matthew, Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138, Walpole, Samuel, Bibic, Lucka, Cromer, Brett, Angulo, Jesus ORCID: https://orcid.org/0000-0001-7250-5639, Sanderson, Julie, Stebbing, Martin and Stokes, Leanne ORCID: https://orcid.org/0000-0003-4013-6781 (2019) Ginsenosides act as positive modulators of P2X4 receptors. Molecular Pharmacology, 95 (2). pp. 210-221. ISSN 0026-895X

Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138, Dhuna, Kshitija, Helliwell, Ray and Stokes, Leanne ORCID: https://orcid.org/0000-0003-4013-6781 (2019) Positive allosteric modulation of P2X7 promotes apoptotic cell death over lytic cell death responses in macrophages. Cell Death & Disease, 10. ISSN 2041-4889

Stappers, Mark H T, Clark, Alexandra E, Aimanianda, Vishukumar, Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138, Reid, Delyth M, Asamaphan, Patawee, Hardison, Sarah E, Dambuza, Ivy M, Valsecchi, Isabel, Kerscher, Bernhard, Plato, Anthony, Wallace, Carol A, Yuecel, Raif, Hebecker, Betty, da Glória Teixeira Sousa, Maria, Cunha, Cristina, Liu, Yan, Feizi, Ten, Brakhage, Axel A, Kwon-Chung, Kyung J, Gow, Neil A R, Zanda, Matteo, Piras, Monica, Zanato, Chiara, Jaeger, Martin, Netea, Mihai G, van de Veerdonk, Frank L, Lacerda, João F, Campos, António, Carvalho, Agostinho, Willment, Janet A, Latgé, Jean-Paul and Brown, Gordon D (2018) Recognition of DHN-melanin by a C-type lectin receptor is required for immunity to Aspergillus. Nature, 555. 382–386. ISSN 0028-0836

Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138 and Schelenz, Silke (2016) A sweet response to a sour situation: The role of soluble pattern recognition receptors in the innate immune response to invasive Aspergillus fumigatus infections. PLoS Pathogens, 12 (7). ISSN 1553-7374

Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138, Sexton, Darren W. and Schelenz, Silke (2016) Serum opsonin ficolin-A enhances host–fungal interactions and modulates cytokine expression from human monocyte-derived macrophages and neutrophils following Aspergillus fumigatus challenge. Medical Microbiology and Immunology, 205 (2). pp. 133-142. ISSN 0300-8584

Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138, Sexton, Darren W, Yates, Matthew, Abdolrasouli, Alireza, Shah, Anand, Wallis, Russell, Reed, Anna, Armstrong-James, Darius and Schelenz, Silke (2015) H-ficolin binds Aspergillus fumigatus leading to activation of the lectin complement pathway and modulation of lung epithelial immune responses. Immunology, 146 (2). pp. 281-291. ISSN 0019-2805

Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138, Sexton, Darren W., Abdolrasouli, Alireza, Shah, Anand, Reed, Anna, Armstrong-James, Darius and Schelenz, Silke (2015) The serum opsonin L-ficolin is detected in lungs of human transplant recipients following fungal infections and modulates inflammation and killing of Aspergillus fumigatus. Journal of Infectious Diseases, 212 (2). pp. 234-246. ISSN 0022-1899

Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138, Kenawy, Hany, Ali, Youssif M, Sexton, Darren, Schwaeble, Wilhelm J and Schelenz, Silke (2013) Role of ficolin-A and lectin complement pathway in the innate defense against pathogenic Aspergillus species. Infection and Immunity, 81 (5). pp. 1730-40. ISSN 0019-9567

Schelenz, Silke, Kirchhof, Nicole, Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138, Wallis, Russell and Sexton, Darren W. (2013) Opsonizing properties of rat ficolin-A in the defence against Cryptococcus neoformans. Immunobiology, 218 (4). pp. 477-83. ISSN 1878-3279

Sivaramakrishnan, V., Bidula, S. ORCID: https://orcid.org/0000-0002-3790-7138, Campwala, H., Katikaneni, D. and Fountain, S. J. ORCID: https://orcid.org/0000-0002-6028-0548 (2012) Constitutive lysosome exocytosis releases ATP and engages P2Y receptors in human monocytes. Journal of Cell Science, 125 (19). pp. 4567-4575. ISSN 0021-9533

Book Section

Middleton, Georgie and Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138 (2025) Immunology of Fungal Infections. In: Encyclopedia of Immunobiology. Elsevier, V4:6-V4:17. ISBN 9780123742797

Stokes, Leanne ORCID: https://orcid.org/0000-0003-4013-6781, Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138 and Sluyter, Ronald (2024) Purinergic P2X Receptors as Therapeutic Targets. In: Ion Channels as Targets in Drug Discovery. Springer, pp. 439-460. ISBN 9783031521966

Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138 and Brown, Gordon D. (2016) Immunology of Fungal Infections. In: Encyclopedia of Immunobiology. Elsevier, pp. 75-82. ISBN 978-0-08-092152-5