Items where Author is "Bidula, Stefan"

Johnson, Robert T., Wostear, Finn, Solanki, Reesha, Steward, Oliver, Bradford, Alice, Morris, Christopher, Bidula, Stefan and Warren, Derek T. (2024) A microtubule stability switch alters isolated vascular smooth muscle Ca2+ flux in response to matrix rigidity. Journal of Cell Science, 137 (21). ISSN 0021-9533

Bidula, Stefan, Piyasirananda, Waraporn, Bielecka, Hanna, Bibič, Lučka, Beekman, Andrew and Stokes, Leanne (2024) Screening herbal and natural product libraries to aid discovery of novel allosteric modulators of human P2X7. Purinergic Signalling. ISSN 1573-9538

Johnson, Robert T., Solanki, Reesha, Wostear, Finn, Ahmed, Sultan, Taylor, James C. K., Rees, Jasmine, Abel, Geraad, McColl, James, Jørgensen, Helle F., Morris, Chris J., Bidula, Stefan and Warren, Derek T. (2024) Piezo1-mediated regulation of smooth muscle cell volume in response to enhanced extracellular matrix rigidity. British Journal of Pharmacology, 181 (11). pp. 1576-1595. ISSN 0007-1188

Stokes, Leanne, Bidula, Stefan and Sluyter, Ronald (2024) Purinergic P2X Receptors as Therapeutic Targets. In: Ion Channels as Targets in Drug Discovery. Springer, pp. 439-460. ISBN 9783031521966

Middleton, Georgie and Bidula, Stefan (2024) Immunology of Fungal Infections. In: Reference Module in Life Sciences. Elsevier. ISBN 9780128096338

Porubiaková, Otília, Havlík, Jan, Indu, Šedý, Michal, Přepechalová, Veronika, Bartas, Martin, Bidula, Stefan, Šťastný, Jiří, Fojta, Miroslav and Brázda, Václav (2023) Variability of inverted repeats in all available genomes of bacteria. Microbiology Spectrum, 11 (4). ISSN 2165-0497

Bidula, Stefan and Brázda, Václav (2023) Genomic analysis of non-B nucleic acids structures in SARS-CoV-2: Potential key roles for these structures in mutability, translation, and replication? Genes, 14 (1). ISSN 2073-4425

Dobrovolná, Michaela, Brázda, Václav, Warner, Emily F. and Bidula, Stefan (2022) Inverted repeats in the monkeypox virus genome are hot spots for mutation. Journal of Medical Virology, 95 (1). ISSN 0146-6615

Bohálová, Natália, Dobrovolná, Michaela, Brázda, Václav and Bidula, Stefan (2022) Conservation and over-representation of G-quadruplex sequences in regulatory regions of mitochondrial DNA across distinct taxonomic sub-groups. Biochimie, 194. pp. 28-34. ISSN 0300-9084

Bidula, Stefan, Nadzirin, Izzuddin Bin, Cominetti, Marco, Hickey, Harry, Cullum, Sean A., Searcey, Mark, Schmid, Ralf and Fountain, Samuel J. (2022) Structural basis of the negative allosteric modulation of 5-BDBD at human P2X4 receptors. Molecular Pharmacology, 101 (1). pp. 33-44. ISSN 1521-0111

Stokes, Leanne, Bielecka, Hanna, Felgate, Matthew, Beekman, Andrew, Ngameni, Bathelemy, Chi, Godloves Fru, Stephenson, Richard and Bidula, Stefan (2021) Dioscin-related glycosides as positive allosteric modulators of P2X7 receptors. British Journal of Pharmacology, 178 (24). p. 4947. ISSN 0007-1188

Ghandhi, Laura H. D., Bidula, Stefan, Pask, Christopher M., Lord, Rianne M. and McGowan, Patrick C. (2021) Bis(N-picolinamido)cobalt(II) complexes display antifungal activity toward Candida albicans and Aspergillus fumigatus. ChemMedChem, 16 (20). pp. 3210-3221. ISSN 1860-7179

Bidula, Stefan (2021) Analysis of putative G-quadruplex forming sequences in inflammatory mediators and their potential as targets for treating inflammatory disorders. Cytokine, 142. ISSN 1043-4666

Warner, Emily F., Bohálová, Natália, Brázda, Václav, Waller, Zoë A. E. and Bidula, Stefan (2021) Analysis of putative quadruplex-forming sequences in fungal genomes: Novel antifungal targets? Microbial Genomics, 7 (5). ISSN 2057-5858

Piyasirananda, Waraporn, Beekman, Andrew, Ganesan, A., Bidula, Stefan and Stokes, Leanne (2021) Insights into the structure-activity relationship of glycosides as positive allosteric modulators acting on P2X7 receptors. Molecular Pharmacology, 99 (2). pp. 163-174. ISSN 0026-895X

Bidula, Stefan, Bibic, Lucka, Moulton, Adrienne, Zhang, Jiayi and Stokes, Leanne (2020) Revisiting the past to enhance the future:Traditional medicinal plant extracts in the discovery of novel drug lead to target P2X7. British Journal of Pharmacology, 177 (11). pp. 2628-2629. ISSN 0007-1188

Stokes, Leanne, Bidula, Stefan, Bibič, Lučka and Allum, Elizabeth (2020) To inhibit or enhance? Is there a benefit to positive allosteric modulation of P2X receptors? Frontiers in Pharmacology, 11. ISSN 1663-9812

Bidula, S., Dhuna, K., Helliwell, R., Stebbing, M. and Stokes, L. (2019) Herbaceous homicide:The Panax ginseng metabolite compound K accelerates caspase-3/7 activation and enhances macrophage cell death in a P2X7-dependent manner. British Journal of Pharmacology, 176 (16). p. 3028. ISSN 0007-1188

Bidula, Stefan M., Cromer, Brett A., Walpole, Samuel, Angulo, Jesus and Stokes, Leanne (2019) Mapping a novel positive allosteric modulator binding site in the central vestibule region of human P2X7. Scientific Reports, 9. ISSN 2045-2322

Bidula, Stefan, Sexton, Darren and Schelenz, Silke (2019) Ficolins and the recognition of pathogenic microorganisms: An overview of the innate immune response and contribution of single nucleotide polymorphisms. Journal of Immunology Research, 2019. ISSN 2314-7156

Dhuna, Kshitija, Felgate, Matthew, Bidula, Stefan, Walpole, Samuel, Bibic, Lucka, Cromer, Brett, Angulo, Jesus, Sanderson, Julie, Stebbing, Martin and Stokes, Leanne (2019) Ginsenosides act as positive modulators of P2X4 receptors. Molecular Pharmacology, 95 (2). pp. 210-221. ISSN 0026-895X

Bidula, Stefan, Dhuna, Kshitija, Helliwell, Ray and Stokes, Leanne (2019) Positive allosteric modulation of P2X7 promotes apoptotic cell death over lytic cell death responses in macrophages. Cell Death & Disease, 10. ISSN 2041-4889

Stappers, Mark H T, Clark, Alexandra E, Aimanianda, Vishukumar, Bidula, Stefan, Reid, Delyth M, Asamaphan, Patawee, Hardison, Sarah E, Dambuza, Ivy M, Valsecchi, Isabel, Kerscher, Bernhard, Plato, Anthony, Wallace, Carol A, Yuecel, Raif, Hebecker, Betty, da Glória Teixeira Sousa, Maria, Cunha, Cristina, Liu, Yan, Feizi, Ten, Brakhage, Axel A, Kwon-Chung, Kyung J, Gow, Neil A R, Zanda, Matteo, Piras, Monica, Zanato, Chiara, Jaeger, Martin, Netea, Mihai G, van de Veerdonk, Frank L, Lacerda, João F, Campos, António, Carvalho, Agostinho, Willment, Janet A, Latgé, Jean-Paul and Brown, Gordon D (2018) Recognition of DHN-melanin by a C-type lectin receptor is required for immunity to Aspergillus. Nature, 555. 382–386. ISSN 0028-0836

Bidula, Stefan and Schelenz, Silke (2016) A sweet response to a sour situation: The role of soluble pattern recognition receptors in the innate immune response to invasive Aspergillus fumigatus infections. PLoS Pathogens, 12 (7). ISSN 1553-7374

Bidula, Stefan and Brown, Gordon D. (2016) Immunology of Fungal Infections. In: Encyclopedia of Immunobiology. Elsevier, pp. 75-82. ISBN 978-0-08-092152-5

Bidula, Stefan, Sexton, Darren W. and Schelenz, Silke (2016) Serum opsonin ficolin-A enhances host–fungal interactions and modulates cytokine expression from human monocyte-derived macrophages and neutrophils following Aspergillus fumigatus challenge. Medical Microbiology and Immunology, 205 (2). pp. 133-142. ISSN 0300-8584

Bidula, Stefan, Sexton, Darren W, Yates, Matthew, Abdolrasouli, Alireza, Shah, Anand, Wallis, Russell, Reed, Anna, Armstrong-James, Darius and Schelenz, Silke (2015) H-ficolin binds Aspergillus fumigatus leading to activation of the lectin complement pathway and modulation of lung epithelial immune responses. Immunology, 146 (2). pp. 281-291. ISSN 0019-2805

Bidula, Stefan, Sexton, Darren W., Abdolrasouli, Alireza, Shah, Anand, Reed, Anna, Armstrong-James, Darius and Schelenz, Silke (2015) The serum opsonin L-ficolin is detected in lungs of human transplant recipients following fungal infections and modulates inflammation and killing of Aspergillus fumigatus. Journal of Infectious Diseases, 212 (2). pp. 234-246. ISSN 0022-1899

Bidula, Stefan, Kenawy, Hany, Ali, Youssif M, Sexton, Darren, Schwaeble, Wilhelm J and Schelenz, Silke (2013) Role of ficolin-A and lectin complement pathway in the innate defense against pathogenic Aspergillus species. Infection and Immunity, 81 (5). pp. 1730-40. ISSN 0019-9567

Schelenz, Silke, Kirchhof, Nicole, Bidula, Stefan, Wallis, Russell and Sexton, Darren W. (2013) Opsonizing properties of rat ficolin-A in the defence against Cryptococcus neoformans. Immunobiology, 218 (4). pp. 477-83. ISSN 1878-3279

Sivaramakrishnan, V., Bidula, S., Campwala, H., Katikaneni, D. and Fountain, S. J. (2012) Constitutive lysosome exocytosis releases ATP and engages P2Y receptors in human monocytes. Journal of Cell Science, 125 (19). pp. 4567-4575. ISSN 0021-9533