Items where Research Group is "Synthetic and Medicinal Chemistry

A

Aljuhani, Ateyatallah, Said, Musa A., Hughes, David L. and Cammidge, Andrew N. (2018) Synthesis and crystal structure of 1,3-bis[(3,4-dicyano)phenoxy]-4,6-dinitro-benzene, C22H8N6O6. Zeitschrift für Kristallographie - New Crystal Structures, 233 (5). 853–855. ISSN 1433-7266

Anwar, Awais, Gould, Emma, Tinson, Ryan, Iqbal, Javaid and Hamilton, Chris (2018) Redox modulation at work: Natural phytoprotective polysulfanes from Alliums based on redox-active sulfur. Current Pharmacology Reports, 4 (5). 397–407. ISSN 2198-641X

B

Barad, Seema, Kreouzis, Theo, Cammidge, Andrew N., Cook, Michael J. and Ray, Asim K. (2018) Newly synthesised gadolinium bis-phthalocyanine sandwich complex: Ambipolar organic semiconductor. Semiconductor Science and Technology, 33. ISSN 0268-1242

C

Chaliha, Chayanika, Rugen, Michael D., Field, Robert A. and Kalita, Eeshan (2018) Glycans as modulators of plant defense against filamentous pathogens. Frontiers in Plant Science, 9. ISSN 1664-462X

Crack, Jason C., Hamilton, Chris J. and Le Brun, Nick E. (2018) Mass spectrometric detection of iron nitrosyls, sulfide oxidation and mycothiolation during nitrosylation of the NO sensor [4Fe-4S] NsrR. Chemical Communications, 54 (47). pp. 5992-5995. ISSN 1359-7345

Craggs, Peter D., Mouilleron, Stephane, Rejzek, Martin, de Chiara, Cesira, Young, Robert J., Field, Robert A., Argyrou, Argyrides and de Carvalho, Luiz Pedro S. (2018) The mechanism of acetyl transfer catalyzed by Mycobacterium tuberculosis GlmU. Biochemistry, 57 (24). pp. 3387-3401. ISSN 0006-2960

F

Figueredo, Andreza S., Zamoner, Luis O. B., Rejzek, Martin, Field, Robert A. and Carvalho, Ivone (2018) Cluster glycosides and heteroglycoclusters presented in alternative arrangements. Tetrahedron Letters, 59 (50). pp. 4405-4409. ISSN 0040-4039

G

García Calavia, Paula, Chambrier, Isabelle, Cook, Michael J., Haines, Alan H., Field, Robert A. and Russell, David A. (2018) Targeted photodynamic therapy of breast cancer cells using lactose-phthalocyanine functionalized gold nanoparticles. Journal of Colloid and Interface Science, 512. pp. 249-259. ISSN 0021-9797

Gardiner, William, Camilleri, Matthew, Martinez Lozano, Luis Angel, Bew, Sean and Stephenson, G. Richard (2018) Upper-rim monofunctionalisation in the synthesis of triazole- and disulfide-linked multicalix[4]- and -[6]arenes. Chemistry - A European Journal, 24 (71). pp. 19089-19097. ISSN 0947-6539

H

Hems, Edward S., Nepogodiev, Sergey A., Rejzek, Martin and Field, Robert A. (2018) Synthesis of glyceryl glycosides related to A-type prymnesin toxins. Carbohydrate Research, 463. pp. 14-23. ISSN 0008-6215

Hems, Edward S., Wagstaff, Ben A., Saalbach, Gerhard and Field, Robert A. (2018) CuAAC click chemistry for the enhanced detection of novel alkyne-based natural product toxins. Chemical Communications, 54 (86). pp. 12234-12237. ISSN 1359-7345

Hiras, Jennifer, Sharma, Sunil V., Raman, Vidhyavathi, Tinson, Ryan A. J., Arbach, Miriam, Rodrigues, Dominic F., Norambuena, Javiera, Hamilton, Chris J. and Hanson, Thomas E. (2018) Physiological studies of Chlorobiaceae suggest that bacillithiol derivatives are the most widespread thiols in bacteria. mBIO, 9 (6). ISSN 2150-7511

I

Imber, Marcel, Huyen, Nguyen Thi Thu, Pietrzyk-Brzezinska, Agnieszka J., Loi, Vu Van, Hillion, Melanie, Bernhardt, Jörg, Thärichen, Lena, Kolšek, Katra, Saleh, Malek, Hamilton, Chris J., Adrian, Lorenz, Gräter, Frauke, Wahl, Markus C. and Antelmann, Haike (2018) Protein S-bacillithiolation functions in thiol protection and redox regulation of the glyceraldehyde-3-phosphate dehydrogenase gap in Staphylococcus aureus under hypochlorite stress. Antioxidants & Redox Signaling, 28 (6). pp. 410-430. ISSN 1523-0864

Imber, Marcel, Loi, Vu Van, Reznikov, Sylvia, Fritsch, Verena Nadin, Pietrzyk-Brzezinska, Agnieszka J., Prehn, Janek, Hamilton, Chris, Wahl, Markus C., Bronowska, Agnieszka K. and Antelmann, Haike (2018) The aldehyde dehydrogenase AldA contributes to the hypochlorite defense and is redox-controlled by protein S-bacillithiolation in Staphylococcus aureus. Redox Biology, 15. 557–568. ISSN 2213-2317

J

Jiménez Tejada, Juan A., Lopez-Varo, Pilar, Chaure, Nandu B., Chambrier, Isabelle, Cammidge, Andrew N., Cook, Michael J., Jafari-Fini, Ali and Ray, Asim K. (2018) Organic thin film transistors using a liquid crystalline palladium phthalocyanine as active layer. Journal of Applied Physics, 123 (11). ISSN 0021-8979

K

Kuhaudomlarp, Sakonwan, Patron, Nicola J., Henrissat, Bernard, Rejzek, Martin, Saalbach, Gerhard and Field, Robert A. (2018) Identification of Euglena gracilis β-1,3-glucan phosphorylase and establishment of a new glycoside hydrolase (GH) family GH149. Journal of Biological Chemistry, 293 (8). pp. 2865-2876. ISSN 0021-9258

L

Louveau, Thomas, Orme, Anastasia, Pfalzgraf, Hans, Stephenson, Michael J., Melton, Rachel, Saalbach, Gerhard, Hemmings, Andrew M., Leveau, Aymeric, Rejzek, Martin, Vickerstaff, Robert, Langdon, Tim, Field, Robert and Osbourn, Anne (2018) Analysis of two new Arabinosyltransferases belonging to the carbohydrate-active enzyme (CAZY) Glycosyl Transferase Family1 provides insights into disease resistance and sugar donor specificity. Plant Cell, 30 (12). pp. 3038-3057. ISSN 1532-298X

M

Mills, Shirley, Howell, Lesley, Beekman, Andrew, Stokes, Leanne and Mueller, Anja (2018) Rac1 plays a role in CXCL12 but not CCL3-induced chemotaxis and Rac1 GEF inhibitor NSC23766 has off target effects on CXCR4. Cellular Signalling, 42. 88–96. ISSN 0898-6568

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Panpetch, Pawinee, Field, Robert A. and Limpaseni, Tipaporn (2018) Cloning of the full-length isoamylase3 gene from cassava Manihot esculenta Crantz ‘KU50’ and its heterologous expression in E. coli. Plant Physiology and Biochemistry, 132. pp. 281-286. ISSN 0981-9428

Panpetch, Pawinee, Field, Robert A. and Limpaseni, Tipaporn (2018) Heterologous co-expression in E. coli of isoamylase genes from cassava Manihot esculenta Crantz ‘KU50’ achieves enzyme-active heteromeric complex formation. Plant Molecular Biology, 96 (4-5). pp. 417-427. ISSN 0167-4412

R

Rugen, Michael D., Rejzek, Martin, Naested, Henrik, Svensson, Birte and Field, Robert A. (2018) High-throughput in vitro screening for inhibitors of cereal α-glucosidase. In: Methods in Molecular Biology. Methods in Molecular Biology . Humana Press Inc, pp. 101-115.

Rugen, Michael D., Vernet, Mathieu M. J. L., Hantouti, Laila, Soenens, Amalia, Andriotis, Vasilios M. E., Rejzek, Martin, Brett, Paul, van den Berg, Richard J. B. H. N., Aerts, Johannes M. F. G., Overkleeft, Hermen S. and Field, Robert A. (2018) A chemical genetic screen reveals that iminosugar inhibitors of plant glucosylceramide synthase inhibit root growth in Arabidopsis and cereals. Scientific Reports, 8 (1). ISSN 2045-2322

S

Salomone-Stagni, Marco, Bartho, Joseph D., Kalita, Eeshan, Rejzek, Martin, Field, Robert A., Bellini, Dom, Walsh, Martin A. and Benini, Stefano (2018) Structural and functional analysis of Erwinia amylovora SrlD. The first crystal structure of a sorbitol-6-phosphate 2-dehydrogenase. Journal of Structural Biology, 203 (2). pp. 109-119. ISSN 1047-8477

Steel, Richard J., O'Connell, Maria A. and Searcey, Mark (2018) Perfluoroarene-based peptide macrocycles that inhibit the Nrf2/Keap1 interaction. Bioorganic & Medicinal Chemistry Letters, 28 (16). pp. 2728-2731. ISSN 0960-894X

Stephenson, M.J., Reed, J., Brouwer, B. and Osbourn, A. (2018) Transient expression in nicotiana benthamiana leaves for triterpene production at a preparative scale. Journal of Visualized Experiments, 138. ISSN 1940-087X

W

Wagstaff, Ben A., Hems, Edward S., Rejzek, Martin, Pratscher, Jennifer, Brooks, Elliot, Kuhaudomlarp, Sakonwan, O'Neill, Ellis C., Donaldson, Matthew I., Lane, Steven, Currie, John, Hindes, Andrew M., Malin, Gill, Murrell, J. Colin and Field, Robert A. (2018) Insights into toxic Prymnesium parvum blooms: the role of sugars and algal viruses. Biochemical Society Transactions, 46 (2). pp. 413-421. ISSN 0300-5127

Wagstaff, Ben A., Rejzek, Martin and Field, Robert A. (2018) Identification of a Kdn biosynthesis pathway in the haptophyte Prymnesium parvum suggests widespread sialic acid biosynthesis among microalgae. Journal of Biological Chemistry, 293 (42). pp. 16277-16290. ISSN 0021-9258

Wangpaiboon, Karan, Padungros, Panuwat, Nakapong, Santhana, Charoenwongpaiboon, Thanapon, Rejzek, Martin, Field, Robert A. and Pichyangkura, Rath (2018) An α-1,6-and α-1,3-linked glucan produced by Leuconostoc citreum ABK-1 alternansucrase with nanoparticle and film-forming properties. Scientific Reports, 8 (1). ISSN 2045-2322

Williams, Morwen, Bertrand, Benoît, Hughes, David L., Waller, Zoe Ann Ella, Schmidt, Claudia, Ott, Ingo, O'Connell, Maria Anne, Searcey, Mark and Bochmann, Manfred (2018) Cyclometallated Au(III) dithiocarbamate complexes: synthesis, anticancer evaluation and mechanistic studies. Metallomics, 10 (11). pp. 1655-1666. ISSN 1756-5901

Williams, Morwen RM, Bertrand, Benoît, Fernandez-Cestau, Julio, Waller, Zoë AE, O'Connell, Maria A, Searcey, Mark and Bochmann, Manfred (2018) Acridine-decorated cyclometallated gold(III) complexes: synthesis and anti-tumour investigations. Dalton Transactions, 47 (38). pp. 13523-13534. ISSN 1477-9226

X

Xue, Zheyong, Tan, Zhengwei, Huang, Ancheng, Zhou, Yuan, Sun, Juncong, Wang, Xiaoning, Thimmappa, Ramesha B., Stephenson, Michael J., Osbourn, Anne and Qi, Xiaoquan (2018) Identification of key amino acid residues determining product specificity of 2,3-oxidosqualene cyclase in Oryza species. New Phytologist, 218 (3). pp. 1076-1088. ISSN 0028-646X