Items where Research Group is "Synthetic and Medicinal Chemistry

A

Alonso-Moreno, Carlos, Lancaster, Simon J., Wright, Joseph A., Hughes, David L., Zuccaccia, Cristiano, Correa, Adriana, Macchioni, Alceo, Cavallo, Luigi and Bochmann, Manfred (2008) Ligand mobility and solution structures of the metallocenium ion pairs [Me2C(Cp)(fluorenyl)MCH2SiMe3+···X−] (M = Zr, Hf; X = MeB(C6F5)3, B(C6F5)4). Organometallics, 27 (21). pp. 5474-5487. ISSN 1520-6041

Armer, Richard E., Cowley, Phillip and Searcey, Mark (2008) Recent disclosures of clinical drug candidates. Drug News & Perspectives, 21 (3). pp. 183-188. ISSN 0214-0934

B

Bew, S. P. (2008) ORGN 258-Synthesis of tyrosine based calix 4 arenes. Abstracts of Papers of the American Chemical Society, 236. 258-ORGN. ISSN 0065-7727

Bew, S. P. (2008) Organocatalytic asymmetric synthesis of aziridines. Abstracts of Papers of the American Chemical Society, 236. 235-ORGN. ISSN 0065-7727

Bew, S. P. (2008) POLY 64-Synthesis and reactions of calixarenes using microwave irradiation. Abstracts of Papers of the American Chemical Society, 236. 64-POLY. ISSN 0065-7727

Bew, Sean P., Cheesman, Myles R. and Sharma, Sunil V. (2008) Ferrocenium salts mediate para-tert-butylcalixarene synthesis. Chemical Communications (44). pp. 5731-5733. ISSN 1359-7345

C

Cammidge, Andrew N. and Goddard, Victoria H. M. (2008) Synthesis and liquid crystal properties of some 2,6-disubstituted anthracenes. Liquid Crystals, 35 (9). pp. 1145-1150. ISSN 0267-8292

Clé, Carla, Gunning, A. Patrick, Syson, Karl, Bowater, Laura, Field, Robert A. and Bornemann, Stephen (2008) Detection of transglucosidase-catalyzed polysaccharide synthesis on a surface in real time using surface plasmon resonance spectroscopy. Journal of the American Chemical Society, 130 (46). pp. 15234-15235. ISSN 0002-7863

D

Danopoulos, Andreas A., Pugh, David and Wright, Joseph A. (2008) “Pincer” pyridine-dicarbene-iridium complexes: Facile C-H activation and unexpected η2-imidazol-2-ylidene coordination. Angewandte Chemie-International Edition, 47 (50). pp. 9765-9767. ISSN 1521-3773

Dawson, S. J., Malkinson, J. P., Searcey, M. and Gibbons, S. (2008) ORGN 96-Solid-phase-based synthesis and biological evaluation of quinoxaline antibiotics and structural analogs. Abstracts of Papers of the American Chemical Society, 235. 96-ORGN. ISSN 0065-7727

Dedola, Simone, Nepogodiev, Sergey A., Hughes, David L. and Field, Robert A. (2008) 2,3,4,6-Tetra-O-acetyl-α-D-glucopyranosyl azide. Acta Crystallographica Section C: Crystal Structure Communications, 64 (8). o445-o446. ISSN 0108-2701

de Oliveira, Marcelo T., Hughes, David L., Nepogodiev, Sergey A. and Field, Robert A. (2008) Indirect approach to C-3 branched 1,2-cis-glycofuranosides: synthesis of aceric acid glycoside analogues. Carbohydrate Research, 343 (2). pp. 211-220. ISSN 1873-426X

F

Field, Robert A. (2008) Glycoside Synthesis from 1-Sulfur/Selenium-Substituted Derivatives:Selenoglycosides. In: Handbook of Chemical Glycosylation. Wiley, pp. 361-379. ISBN 9783527317806

H

Hamilton, Chris J., Finlay, Richard M. J., Stewart, Matthew J. G. and Bonner, Alexandra (2008) Mycothiol disulfide reductase: A continuous assay for slow time-dependent inhibitors. Analytical Biochemistry, 388 (1). pp. 91-96. ISSN 1096-0309

Hampshire, Andrew J., Rusling, David A., Bryan, Stephanie, Paumier, David, Dawson, Simon J., Malkinson, John P., Searcey, Mark and Fox, Keith R. (2008) DNA binding by analogues of the bifunctional intercalator TANDEM. Biochemistry, 47 (30). pp. 7900-7906.

Homden, Damien, Redshaw, Carl, Wright, Joseph A., Hughes, David L. and Elsegood, Mark R. J. (2008) Early transition metal complexes bearing a C-capped tris(phenolate) ligand incorporating a pendant imine arm: Synthesis, structure, and ethylene polymerization behavior. Inorganic Chemistry, 47 (13). pp. 5799-5814.

J

Jothivasan, V. K. and Hamilton, C. J. (2008) Mycothiol: synthesis, biosynthesis and biological functions of the major low molecular weight thiol in actinomycetes. Natural Product Reports, 25 (6). pp. 1091-1117. ISSN 0265-0568

K

Karamanska, Rositsa, Clarke, Jonathan, Blixt, Ola, MacRae, James I., Zhang, Jiquan Q., Crocker, Paul R., Laurent, Nicolas, Wright, Adam, Flitsch, Sabine L., Russell, David A. and Field, Robert A. (2008) Surface plasmon resonance imaging for real-time, label-free analysis of protein interactions with carbohydrate microarrays. Glycoconjugate Journal, 25 (1). pp. 69-74. ISSN 0282-0080

Kärkkäinen, Tiina S., Kartha, K. P. Ravindranathan, MacMillan, Derek and Field, Robert A. (2008) Iodine-mediated glycosylation en route to mucin-related glyco-aminoacids and glycopeptides. Carbohydrate Research, 343 (10-11). pp. 1830-1834. ISSN 0008-6215

M

Mativandiela, Sannah Patience Nkami, Meyer, Jacob Jacobus Marion, Hussein, Ahmed A., Houghton, Peter J., Hamilton, Chris J. and Lall, Namrita (2008) Activity against Mycobacterium smegmatis and M. tuberculosis by extract of South African medicinal plants. Phytotherapy Research, 22 (6). pp. 841-845. ISSN 0951-418X

R

Race, A. D., Pors, K., Shnyder, S. D., Cooper, T. C., Sheldrake, H. M., Searcey, M., Patterson, L. H. and Loadman, P. M. (2008) CYP1A1 activation and pharmacokinetics of a novel chloromethylpyrrollolindoline with potential as a tumour selective prodrug. Ejc Supplements, 6 (12). p. 105. ISSN 1359-6349

S

Sarazin, Yann, Wright, Joseph A., Harding, Duncan A. J., Martin, Eddy, Woodman, Timothy J., Hughes, David L. and Bochmann, Manfred (2008) Synthesis and structures of new binuclear zinc alkyl, aryl and aryloxo complexes. Journal of Organometallic Chemistry, 693 (8-9). pp. 1494-1501.

Schofield, Claire L., Mukhopadhyay, Balaram, Hardy, Sinead M., McDonnell, Martin B., Field, Robert A. and Russell, David A. (2008) Colorimetric detection of Ricinus communis Agglutinin 120 using optimally presented carbohydrate-stabilised gold nanoparticles. The Analyst, 133 (5). pp. 626-634. ISSN 0003-2654

T

Tello, Mónica, Rejzek, Martin, Wilkinson, Barrie, Lawson, David M. and Field, Robert A. (2008) Tyl1a, a TDP-6-deoxy-D-xylo-4-hexulose 3, 4-isomerase from Streptomyces fradiae:Structure prediction, mutagenesis and solvent isotope incorporation experiments to investigate reaction mechanism. ChemBioChem, 9 (8). pp. 1295-1302. ISSN 1439-4227

V

Van Well, Renate M., Collet, Beatrice Y.M. and Field, Robert A. (2008) Synthesis of mucin glycans from the protozoon parasite Trypanosoma cruzi. Synlett (14). pp. 2175-2177. ISSN 0936-5214

W

Westman, Erin L., Preston, Andrew, Field, Robert A. and Lam, Joseph S. (2008) Biosynthesis of a rare di-N-acetylated sugar in the lipopolysaccharides of both Pseudomonas aeruginosa and Bordetella pertussis occurs via an identical scheme despite different gene clusters. Journal of Bacteriology, 190 (18). pp. 6060-6069. ISSN 0021-9193

Wilson, Polly A., Wright, Joseph A., Oganesyan, Vasily S., Lancaster, Simon J. and Bochmann, Manfred (2008) Structural characterization of a cationic zirconocene dimethylaniline complex and related catalytically relevant species. Organometallics, 27 (23). pp. 6371-6374. ISSN 1520-6041

Z

Zhi, Zheng-Liang, Laurent, Nicolas, Powell, Andrew K., Karamanska, Rositsa, Fais, Margherita, Voglmeir, Josef, Wright, Adam, Blackburn, Jonathan M., Crocker, Paul R., Russell, David A., Flitsch, Sabine, Field, Rob A. and Turnbull, Jeremy E. (2008) A versatile gold surface approach for fabrication and interrogation of glycoarrays. ChemBioChem, 9 (10). pp. 1568-1575. ISSN 1439-7633