Items where Research Group is "Pharmacology and Biological Chemistry

Published

Bebawy, George, Sanderson, Julie and Qi, Sheng (2025) Nanoelectrospray fabrication of pH-responsive double-layered drug-eluting contact lenses for ocular drug delivery. International Journal of Pharmaceutics, 686. ISSN 0378-5173

Bidula, Stefan, Piyasirananda, Waraporn, Bielecka, Hanna, Bibič, Lučka, Beekman, Andrew and Stokes, Leanne (2025) Screening herbal and natural product libraries to aid discovery of novel allosteric modulators of human P2X7. Purinergic Signalling, 21 (2). 365–379. ISSN 1573-9538

Bradley, Justin M., Bugg, Zinnia, Moore, Geoffrey R., Hemmings, Andrew M. and Le Brun, Nick E. (2025) Observation of the assembly of the nascent mineral core at the nucleation site of human mitochondrial ferritin. Journal of the American Chemical Society, 147 (16). 13699–13710. ISSN 0002-7863

Bradley, Justin M., Bugg, Zinnia, Pullin, Jacob, Moore, Geoffrey R., Svistunenko, Dimitri A. and Le Brun, Nick E. (2025) Human mitochondrial ferritin exhibits highly unusual iron-O2 chemistry distinct from that of cytosolic ferritins. Nature Communications, 16. ISSN 2041-1723

Bradley, Justin M., Carter, Aiden M., Bugg, Zinnia, Andrews, Simon C. and Le Brun, Nick E. (2025) The iron-sulfur cluster of bacterioferritin-associated ferredoxin (Bfd): A "biological fuse" that prevents oxidative damage to cells? Angewandte Chemie International Edition, 64 (34). ISSN 1433-7851

Braymer, Joseph, Knauer, Lukas, Crack, Jason, Oltmanns, Jonathan, Heghmanns, Melanie, Soares, Jessica, Le Brun, Nick, Schunemann, Volker and Kasanmascheff, Muge (2025) Yeast [FeFe]-hydrogenase-like protein Nar1 binds a [2Fe-2S] cluster. Chemical Science. ISSN 2041-6520

Collins, Kyle, Williamson, David, Marin, Maria J., Jones, Adam and Kemsley, E. Kate (2025) Quantitative NMR Estimation of Primary Metabolites in Turmeric Spice. In: Experimental Nuclear Magnetic Resonance Conference 2025, 2025-04-06 - 2025-04-10, Asilomar Conference Center, Pacific Grove, California.

Crack, Jason C., Harvey, Lauren R., Johnson, Katie E. and Le Brun, Nick E. (2025) ArnR binds a [4Fe-4S] cluster and indirectly senses anaerobicity in Corynebacteria. Metallomics, 17 (8). ISSN 1756-5901

Crack, Jason C. and Le Brun, Nick E. (2025) Synergy of native mass spectrometry and other biophysical techniques in studies of iron sulfur cluster proteins and their assembly. Biochimica Et Biophysica Acta-Molecular Cell Research, 1872 (1). ISSN 0167-4889

Golubova, Daria, Salmon, Melissa, Su, Honghao, Tansley, Connor, Kaithakottil, Gemy George, Linsmith, Gareth, Schudoma, Christian, Swarbreck, David, O'Connell, Maria A. and Patron, Nicola J. (2025) Biosynthesis and bioactivity of anti-inflammatory triterpenoids in Calendula officinalis. Nature Communications, 16. ISSN 2041-1723

Gray, Elizabeth, Gao, Miaomiao, Bradley, Justin, Crack, Jason C. and Le Brun, Nick E. (2025) Cluster occupancy- and oxidation state-dependence of Yersinia enterocolitica IscR DNA binding. Journal of Inorganic Biochemistry, 272. ISSN 0162-0134

Hofmann, Benjamin J., Aljohani, Enas T., Cicovacki, Natalia, Lee, Ivan, Warren, Derek T., Sobolewski, Anastasia, Stringer, Tameryn and Lord, Rianne M. (2025) Ferrocenyl β-diketonate compounds: Extended ring systems for improved anticancer activity. ChemBioChem, 26 (3). ISSN 1439-4227

Middleton, Georgie, Mahamud, Fuad O., Storer, Isabelle S. R., Williams-Gunn, Abigail, Wostear, Finn, Abdolrasouli, Alireza, Barclay, Elaine, Bradford, Alice, Steward, Oliver, Schelenz, Silke, McColl, James, Lézé, Bertrand, van Rhijn, Norman, da Silva Dantas, Alessandra, Furukawa, Takanori, Warren, Derek, Waller, Zoë A. E. and Bidula, Stefan (2025) Evidence that G-quadruplexes form in pathogenic fungi and represent promising antifungal targets. EMBO Molecular Medicine, 17. 3636–3656. ISSN 1757-4676

Monaco, Serena, Browne, Jacob, Wallace, Matthew, Angulo, Jesús and Stokes, Leanne (2025) On-cell saturation transfer difference NMR spectroscopy on ion channels: Characterizing negative allosteric modulator binding interactions of P2X7. Journal of the American Chemical Society, 147 (36). 32400–32411. ISSN 0002-7863

Niyadurupola, Nuwan, Sidaway, Peter, Broadway, David C. and Sanderson, Julie (2025) The P2X7 receptor regulates IL-1β secretion in the human retina. International Journal of Molecular Medicine, 26 (21). ISSN 1107-3756

Pullin, Jacob, Rodríguez-Celma, Jorge, Franceschetti, Marina, Mundy, Julia E. A., Svistunenko, Dimitri A., Bradley, Justin M., Le Brun, Nick E. and Balk, Janneke (2025) Iron-sensing and redox properties of the hemerythrin-like domains of Arabidopsis BRUTUS and BRUTUS-LIKE2 proteins. Nature Communications, 16. ISSN 2041-1723

Tammam, Mohamed A., Pereira, Florbela, Skellam, Elizabeth, Bidula, Stefan, Ganesan, A. and El-Demerdash, Amr (2025) The cytochalasans: Potent fungal natural products with application from bench to bedside. Natural Product Reports, 42 (5). pp. 788-841. ISSN 0265-0568

Tolchard, James, Chambers, Vicki S., Boutemy, Laurence S., Banfield, Mark J. and Blumenschein, Tharin M. A. (2025) Dynamics in the Phytophthora capsici effector AVR3a11 confirm the core WY domain fold. Biochemistry, 64 (5). 1146–1156. ISSN 0006-2960

Warner, E. F., Guneri, D., O'Connell, M. A., Macdonald, C. J. and Waller, Z. A. E. (2025) Modulation of Nrf2 expression by targeting i-motif DNA. Communications Chemistry, 8. ISSN 2399-3669