Items where Author is "Hellmich, Charlotte"

Moreno-Gonzalez, Mar, Hampton, Katherine, Ruiz, Paula, Beasy, Gemma, Nagies, Falk S. P., Parker, Aimee, Lazenby, James, Bone, Caitlin, Alava-Arteaga, Ane, Patel, Meha, Hellmich, Charlotte, Luri-Martin, Pablo, Silan, Ece, Philo, Mark, Baker, David, Rushbrook, Simon M., Hildebrand, Falk, Rushworth, Stuart A. and Beraza, Naiara (2024) Regulation of intestinal senescence during cholestatic liver disease modulates barrier function and liver disease progression. JHEP Reports, 6 (10). ISSN 2589-5559

Wojtowicz, Edyta E., Hampton, Katherine, Moreno-Gonzalez, Mar, Utting, Charlotte L., Lan, Yuxuan, Ruiz, Paula, Beasy, Gemma, Bone, Caitlin, Hellmich, Charlotte, Maynard, Rebecca, Acton, Luke, Markham, Matthew, Troeberg, Linda ORCID: https://orcid.org/0000-0003-0939-4651, Telatin, Andrea, Kingsley, Robert A. ORCID: https://orcid.org/0000-0002-0194-6485, Macaulay, Iain C., Rushworth, Stuart A. and Beraza, Naiara (2024) Low protein diet protects the liver from Salmonella Typhimurium-mediated injury by modulating the mTOR/autophagy axis in macrophages. Communications Biology, 7. ISSN 2399-3642

Fowler-Shorten, Dominic J., Maynard, Rebecca S., Hampton, Katherine, Altera, Annalisa, Markham, Matthew, Ehikioya, Martha, Wojtowicz, Edyta E., Bowles, Kristian M. ORCID: https://orcid.org/0000-0003-1334-4526, Rushworth, Stuart A. and Hellmich, Charlotte (2024) Acute myeloid leukemia driven IL-3-dependent upregulation of BCL2 in non-malignant hematopoietic stem and progenitor cells increases venetoclax-induced cytopenias. Haematologica, 109 (5). pp. 1576-1581. ISSN 0390-6078

Wojtowicz, Edyta E., Mistry, Jayna J., Uzun, Vladimir, Hellmich, Charlotte, Scoones, Anita, Chin, Desmond W., Kettyle, Laura M., Grasso, Francesca, Lord, Allegra M., Wright, David J., Etherington, Graham J., Woll, Petter S., Belderbos, Mirjam E., Bowles, Kristian M. ORCID: https://orcid.org/0000-0003-1334-4526, Nerlov, Claus, Haerty, Wilfried ORCID: https://orcid.org/0000-0003-0111-191X, Bystrykh, Leonid V., Jacobsen, Sten Eirik W., Rushworth, Stuart A. and Macaulay, Iain C. (2023) Panhematopoietic RNA barcoding enables kinetic measurements of nucleate and anucleate lineages and the activation of myeloid clones following acute platelet depletion. Genome Biology, 24. ISSN 1474-760X

Jibril, Aisha, Hellmich, Charlotte, Wojtowicz, Edyta E., Hampton, Katherine, Maynard, Rebecca, De Silva, Ravindu ORCID: https://orcid.org/0009-0003-5184-5978, Fowler-Shorten, Dominic J., Mistry, Jayna J., Moore, Jamie A., Bowles, Kristian M. ORCID: https://orcid.org/0000-0003-1334-4526 and Rushworth, Stuart A. (2023) Plasma cell derived mtDAMPs activate macrophage STING pathway which promotes myeloma progression. Blood, 141 (25). 3065–3077. ISSN 0006-4971

Hellmich, Charlotte, Wojtowicz, Edyta, Moore, Jamie A., Mistry, Jayna J., Jibril, Aisha, Johnson, Benjamin B., Smith, James G.W. ORCID: https://orcid.org/0000-0003-0427-8678, Beraza, Naiara, Bowles, Kristian M. ORCID: https://orcid.org/0000-0003-1334-4526 and Rushworth, Stuart A. (2023) p16INK4A-dependent senescence in the bone marrow niche drives age-related metabolic changes of hematopoietic progenitors. Blood Advances, 7 (2). pp. 256-268. ISSN 2473-9529

Kumar, Prakrit R., Saad, Mona, Hellmich, Charlotte, Mistry, Jayna J., Moore, Jamie A., Conway, Shannon, Morris, Christopher J. ORCID: https://orcid.org/0000-0002-7703-4474, Bowles, Kristian M. ORCID: https://orcid.org/0000-0003-1334-4526, Moncrieff, Marc D. and Rushworth, Stuart A. (2022) PGC-1α induced mitochondrial biogenesis in stromal cells underpins mitochondrial transfer to melanoma. British Journal of Cancer, 127. 69–78. ISSN 0007-0920

Moore, Jamie A., Mistry, Jayna J., Hellmich, Charlotte, Horton, Rebecca H., Wojtowicz, Edyta E., Jibril, Aisha, Jefferson, Matthew, Wileman, Thomas, Beraza, Naiara, Bowles, Kristian M. ORCID: https://orcid.org/0000-0003-1334-4526 and Rushworth, Stuart A. (2022) LC3-associated phagocytosis in bone marrow macrophages suppresses acute myeloid leukemia progression through STING activation. Journal of Clinical Investigation, 132 (5). ISSN 0021-9738

Isaacs-Ten, Anna, Moreno-Gonzalez, Mar, Bone, Caitlin, Martens, Andre, Bernuzzi, Federico, Ludwig, Tobias, Hellmich, Charlotte, Hiller, Karsten, Rushworth, Stuart A. and Beraza, Naiara (2022) Metabolic regulation of macrophages by SIRT1 determines activation during cholestatic liver disease in mice. Cellular and Molecular Gastroenterology and Hepatology, 13 (4). pp. 1019-1039. ISSN 2352-345X

Mistry, Jayna J., Hellmich, Charlotte, Moore, Jamie A., Jibril, Aisha, Macaulay, Iain, Moreno-Gonzalez, Mar, Di Palma, Federica, Beraza, Naiara, Bowles, Kristian M. ORCID: https://orcid.org/0000-0003-1334-4526 and Rushworth, Stuart A. (2021) Free fatty-acid transport via CD36 drives β-oxidation-mediated hematopoietic stem cell response to infection. Nature Communications, 12 (1). ISSN 2041-1723

Jibril, Aisha, Hellmich, Charlotte, Moore, Jamie A., Mistry, Jayna, Rushworth, Stuart, Bowles, Kristian ORCID: https://orcid.org/0000-0003-1334-4526 and Willimott, Victoria (2021) Multiple myeloma derived mitochondrial damps induce inflammation in the bone marrow adipose tissue which promotes tumour development. In: UNSPECIFIED.

Lamprinaki, Dimitra, Garcia-Vello, Pilar, Marchetti, Roberta, Hellmich, Charlotte, McCord, Kelli A., Bowles, Kristian M. ORCID: https://orcid.org/0000-0003-1334-4526, Macauley, Matthew S., Silipo, Alba, De Castro, Cristina, Crocker, Paul R. and Juge, Nathalie (2021) Siglec-7 mediates immunomodulation by colorectal cancer-associated Fusobacterium nucleatum ssp. animalis. Frontiers in Immunology, 12. ISSN 1664-3224

Mistry, Jayna J, Hellmich, Charlotte, Lambert, Amelia, Moore, Jamie A, Jibril, Aisha, Collins, Angela, Bowles, Kristian M ORCID: https://orcid.org/0000-0003-1334-4526 and Rushworth, Stuart A (2021) Venetoclax and Daratumumab combination treatment demonstrates pre-clinical efficacy in mouse models of Acute Myeloid Leukemia. Biomarker Research, 9 (1). ISSN 2050-7771

Mistry, Jayna J., Moore, Jamie A., Kumar, Prakritt, Marlein, Christopher R., Hellmich, Charlotte, Pillinger, Genevra, Jibril, Aisha, Di Palma, Federica, Collins, Angela, Bowles, Kristian M. ORCID: https://orcid.org/0000-0003-1334-4526 and Rushworth, Stuart A. (2021) Daratumumab inhibits acute myeloid leukemia metabolic capacity by blocking mitochondrial transfer from mesenchymal stromal cells. Haematologica, 106 (2). pp. 589-592. ISSN 0390-6078

Hellmich, Charlotte, Bowles, Kristian ORCID: https://orcid.org/0000-0003-1334-4526 and Rushworth, Stuart (2020) ARQ531: The therapy that targets multiple pathways in acute myeloid leukemia. Haematologica, 105 (10). pp. 2350-2352. ISSN 0390-6078

Hellmich, Charlotte, Moore, Jamie A., Bowles, Kristian M. ORCID: https://orcid.org/0000-0003-1334-4526 and Rushworth, Stuart A. (2020) Bone marrow senescence and the microenvironment of hematological malignancies. Frontiers in Oncology, 10. ISSN 2234-943X

Mistry, Jayna J., Marlein, Christopher R., Moore, Jamie A., Hellmich, Charlotte, Wojtowicz, Edyta E., Smith, James G. W. ORCID: https://orcid.org/0000-0003-0427-8678, Macaulay, Iain, Sun, Yu, Morfakis, Adam, Patterson, Angela, Horton, Rebecca H., Divekar, Devina, Morris, Christopher J. ORCID: https://orcid.org/0000-0002-7703-4474, Haestier, Anna, Di Palma, Federica, Beraza, Naiara, Bowles, Kristian M. ORCID: https://orcid.org/0000-0003-1334-4526 and Rushworth, Stuart A. (2019) ROS-mediated PI3K activation drives mitochondrial transfer from stromal cells to hematopoietic stem cells in response to infection. Proceedings of the National Academy of Sciences of the United States of America, 116 (49). pp. 24610-24619. ISSN 1091-6490

Marlein, Christopher, Piddock, Rachel E., Mistry, Jayna J., Zaitseva, Lyubov, Hellmich, Charlotte, Horton, Rebecca H., Zhou, Zhigang, Auger, Martin J., Bowles, Kristian M. ORCID: https://orcid.org/0000-0003-1334-4526 and Rushworth, Stuart A. (2019) CD38-driven mitochondrial trafficking promotes bioenergetic plasticity in multiple myeloma. Cancer Research, 79 (9). pp. 2285-2297. ISSN 0008-5472

Abdul-Aziz, Amina M, Sun, Yu, Hellmich, Charlotte, Marlein, Christopher R, Mistry, Jayna, Forde, Eoghan, Piddock, Rachel E, Shafat, Manar S, Morfakis, Adam, Mehta, Tarang, Di Palma, Federica, Macaulay, Iain, Ingham, Christopher J, Haestier, Anna, Collins, Angela, Campisi, Judith, Bowles, Kristian M. ORCID: https://orcid.org/0000-0003-1334-4526 and Rushworth, Stuart A (2019) Acute myeloid leukemia induces pro-tumoral p16INK4a driven senescence in the bone marrow microenvironment. Blood, 133 (5). pp. 446-456. ISSN 0006-4971

Nimmagadda, S C, Frey, S, Edelmann, B, Hellmich, C, Zaitseva, L, König, G M, Kostenis, E, Bowles, K M ORCID: https://orcid.org/0000-0003-1334-4526 and Fischer, T (2018) Bruton’s tyrosine kinase and RAC1 promote cell survival in MLL-rearranged acute myeloid leukemia. Leukemia, 32. 846–849. ISSN 0887-6924