Items where Author is "Pontifex, Matthew"

Article

Connell, Emily, Le Gall, Gwénaëlle ORCID: https://orcid.org/0000-0002-1379-2196, Mcarthur, Simon, Lang, Leonie, Breeze, Bernadette ORCID: https://orcid.org/0000-0002-2563-8823, Liaquat, Marrium ORCID: https://orcid.org/0000-0001-7290-2554, Pontifex, Matthew G. ORCID: https://orcid.org/0000-0003-2174-2313, Sami, Saber, Pourtau, Line, Gaudout, David, Müller, Michael ORCID: https://orcid.org/0000-0002-5930-9905 and Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756 (2026) A novel Mediterranean diet-inspired supplement reduces hippocampal amyloid deposits and microglial activation through the modulation of the microbiota gut-brain axis in 5xFAD mice. Gut Microbes, 18 (1). ISSN 1949-0976

Connell, Emily, Sami, Saber, Khondoker, Mizanur ORCID: https://orcid.org/0000-0002-1801-1635, Minihane, Anne marie ORCID: https://orcid.org/0000-0001-9042-4226, Pontifex, Matthew g. ORCID: https://orcid.org/0000-0003-2174-2313, Müller, Michael ORCID: https://orcid.org/0000-0002-5930-9905, Mcarthur, Simon, Le gall, Gwenaelle ORCID: https://orcid.org/0000-0002-1379-2196 and Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756 (2026) Circulatory dietary and gut-derived metabolites predict early cognitive decline. Gut Microbes, 18 (1). ISSN 1949-0976

Lang, Leonie, Ditton, Annabel, Stanescu, Andi, Jainani, Vernisse, McArthur, Simon, Pourtau, Line, Gaudout, David, Pontifex, Matthew G. ORCID: https://orcid.org/0000-0003-2174-2313, Tsigarides, Jordan ORCID: https://orcid.org/0000-0001-9893-8002, Steward, Taylor, Sami, Saber, Muller, Michael ORCID: https://orcid.org/0000-0002-5930-9905, Hornberger, Michael ORCID: https://orcid.org/0000-0002-2214-3788, Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756 and Lazar, Alpar S. (2025) A standardised saffron extract improves subjective and objective sleep quality in healthy older adults with sleep complaints: results from the Gut-Sleep-Brain Axis randomised, double-blind, placebo-controlled pilot study. Food & Function, 16 (17). pp. 6817-6832. ISSN 2042-6496

Wirkus, Joanna, Ead, Aya S., Krga, Irena, Wang, Yige, Pontifex, Matthew G. ORCID: https://orcid.org/0000-0003-2174-2313, Muller, Michael ORCID: https://orcid.org/0000-0002-5930-9905, Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756, Matsukuma, Karen E., Zhang, Guodong and Mackenzie, Gerardo G. (2025) Normalizing body weight with a dietary strategy mitigates obesity-accelerated pancreatic carcinogenesis in mice. The Journal of Nutrition, 155 (8). pp. 2668-2684. ISSN 0022-3166

Liaquat, Marrium ORCID: https://orcid.org/0000-0001-7290-2554, Le Gall, Gwenaelle ORCID: https://orcid.org/0000-0002-1379-2196, Scholey, Andrew, Pontifex, Matthew G. ORCID: https://orcid.org/0000-0003-2174-2313, Bastiaanssen, Thomaz F. S., Muller, Michael ORCID: https://orcid.org/0000-0002-5930-9905, Minihane, Anne Marie ORCID: https://orcid.org/0000-0001-9042-4226 and Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756 (2025) APOE4 genotype shapes the role of dietary fibers in cognitive health through gut microbiota changes. Gut Microbes, 17 (1). ISSN 1949-0976

Liaquat, Marrium ORCID: https://orcid.org/0000-0001-7290-2554, Minihane, Anne Marie ORCID: https://orcid.org/0000-0001-9042-4226, Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756 and Pontifex, Matthew G. ORCID: https://orcid.org/0000-0003-2174-2313 (2025) The gut microbiota in menopause: Is there a role for prebiotic and probiotic solutions? Post Reproductive Health, 31 (2). pp. 105-114. ISSN 2053-3691

Shah, Sita N., Knausenberger, Tobias B.-A., Pontifex, Matthew G. ORCID: https://orcid.org/0000-0003-2174-2313, Connell, Emily, Le Gall, Gwénaëlle ORCID: https://orcid.org/0000-0002-1379-2196, Hardy, Tom A. J., Randall, David W., McCafferty, Kieran, Yaqoob, Muhammad M., Solito, Egle, Müller, Michael ORCID: https://orcid.org/0000-0002-5930-9905, Stachulski, Andrew V., Glen, Robert C., Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756, Hoyles, Lesley and McArthur, Simon (2024) Cerebrovascular damage caused by the gut microbe/host co-metabolite p-cresol sulfate is prevented by blockade of the EGF receptor. Gut Microbes, 16 (1). ISSN 1949-0976

Breeze, Bernadette ORCID: https://orcid.org/0000-0002-2563-8823, Connell, Emily, Wileman, Tom, Muller, Michael ORCID: https://orcid.org/0000-0002-5930-9905, Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756 and Pontifex, Matthew G. ORCID: https://orcid.org/0000-0003-2174-2313 (2024) Menopause and Alzheimer’s disease susceptibility: Exploring the potential mechanisms. Brain Research, 1844. ISSN 1872-6240

Hunt, Thomas, Pontifex, Matthew G. ORCID: https://orcid.org/0000-0003-2174-2313 and Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756 (2024) (Poly)phenols and brain health – beyond their antioxidant capacity. FEBS Letters, 598 (24). pp. 2949-2962. ISSN 0014-5793

Connell, Emily, Le Gall, Gwénaëlle ORCID: https://orcid.org/0000-0002-1379-2196, McArthur, Simon, Lang, Leonie, Breeze, Bernadette ORCID: https://orcid.org/0000-0002-2563-8823, Pontifex, Matthew G. ORCID: https://orcid.org/0000-0003-2174-2313, Sami, Saber, Pourtau, Line, Gaudout, David, Müller, Michael ORCID: https://orcid.org/0000-0002-5930-9905 and Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756 (2024) (Poly)phenol-rich grape and blueberry extract prevents LPS-induced disruption of the blood-brain barrier through the modulation of the gut microbiota-derived uremic toxins. Neurochemistry International, 180. ISSN 0197-0186

Connell, Emily, Blokker, Britt, Kellingray, Lee, Le Gall, Gwénaëlle ORCID: https://orcid.org/0000-0002-1379-2196, Philo, Mark, Pontifex, Matthew G. ORCID: https://orcid.org/0000-0003-2174-2313, Narbad, Arjan, Müller, Michael ORCID: https://orcid.org/0000-0002-5930-9905 and Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756 (2024) Refined diet consumption increases neuroinflammatory signalling through bile acid dysmetabolism. Nutritional Neuroscience, 27 (10). pp. 1088-1101. ISSN 1028-415X

Beghell, Daniela, Giusti, Laura, Zallocco, Lorenzo, Ronci, Maurizio, Cappelli, Alessia, Pontifex, Matthew G. ORCID: https://orcid.org/0000-0003-2174-2313, Muller, Michael ORCID: https://orcid.org/0000-0002-5930-9905, Damiani, Claudia, Cirilli, Ilenia, Hrelia, Silvana, Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756, Vittadini, Elena, Favia, Guido and Angeloni, Cristina (2024) Dietary fiber supplementation increases Drosophila melanogaster lifespan and gut microbiota diversity. Food & Function, 15 (14). pp. 7468-7477. ISSN 2042-6496

Mackenzie, Gerardo G, Wirkus, Joanna, Ead, Aya, Krga, Irena, Matsukuma, Karen, Muller, Michael ORCID: https://orcid.org/0000-0002-5930-9905, Pontifex, Matthew G ORCID: https://orcid.org/0000-0003-2174-2313 and Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756 (2024) The Impact of Fat Quantity and Composition in Pancreatic Carcinogenesis in Mice: Mitigating Obesity-Induced Tumor Progression With Dietary Changes. Current Developments in Nutrition, 8 (Supplement 2). ISSN 2475-2991

Pontifex, Matthew G. ORCID: https://orcid.org/0000-0003-2174-2313, Connell, Emily, Le Gall, Gwenaelle ORCID: https://orcid.org/0000-0002-1379-2196, Lang, Leonie, Pourtau, Line, Gaudout, David, Angeloni, Cristina, Zallocco, Lorenzo, Ronci, Maurizio, Giusti, Laura, Müller, Michael ORCID: https://orcid.org/0000-0002-5930-9905 and Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756 (2024) A novel Mediterranean diet-inspired supplement ameliorates cognitive, microbial, and metabolic deficits in a mouse model of low-grade inflammation. Gut Microbes, 16 (1). ISSN 1949-0976

Wieczorek, Elżbieta, Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756, Pontifex, Matthew G. ORCID: https://orcid.org/0000-0003-2174-2313 and Nuzzo, Domenico (2024) Editorial: Nutrition for an aging brain. Frontiers in Nutrition, 11. ISSN 2296-861X

Láng, Léonie, McArthur, Simon, Lazar, Alpar S., Pourtau, Line, Gaudout, David, Pontifex, Matthew G. ORCID: https://orcid.org/0000-0003-2174-2313, Müller, Michael ORCID: https://orcid.org/0000-0002-5930-9905 and Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756 (2024) Dietary (poly)phenols and the gut–brain axis in ageing. Nutrients, 16 (10). ISSN 2072-6643

Pontifex, Matthew G. ORCID: https://orcid.org/0000-0003-2174-2313, Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756 and Muller, Michael ORCID: https://orcid.org/0000-0002-5930-9905 (2024) Sexual dimorphism in the context of nutrition and health. Proceedings of the Nutrition Society, 83 (2). pp. 109-119. ISSN 0029-6651

Coletto, Erika, Savva, George M., Latousakis, Dimitrios, Pontifex, Matthew ORCID: https://orcid.org/0000-0003-2174-2313, Crost, Emmanuelle H., Vaux, Laura, Telatin, Andrea, Bergstrom, Kirk, Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756 and Juge, Nathalie (2023) Role of mucin glycosylation in the gut microbiota-brain axis of core 3 O-glycan deficient mice. Scientific Reports, 13. ISSN 2045-2322

Martinsen, Anneloes, Saleh, Rasha N. M., Chouinard-Watkins, Raphael, Bazinet, Richard, Harden, Glenn, Dick, James, Tejera, Noemi, Pontifex, Matthew G. ORCID: https://orcid.org/0000-0003-2174-2313, Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756 and Minihane, Anne-Marie ORCID: https://orcid.org/0000-0001-9042-4226 (2023) The influence of APOE genotype, DHA, and flavanol intervention on brain DHA and lipidomics profile in aged transgenic mice. Nutrients, 15 (9). ISSN 2072-6643

Pontifex, Matthew G. ORCID: https://orcid.org/0000-0003-2174-2313, Connell, Emily, Le Gall, Gwenaelle ORCID: https://orcid.org/0000-0002-1379-2196, Pourtau, Line, Gaudout, David, Angeloni, Cristina, Zallocco, Lorenzo, Ronci, Maurizio, Giusti, Laura, Muller, Michael ORCID: https://orcid.org/0000-0002-5930-9905 and Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756 (2022) Saffron extract (Safr’InsideTM) improves anxiety related behaviour in a mouse model of low-grade inflammation through the modulation of the microbiota and gut derived metabolites. Food & Function, 13 (23). pp. 12219-12233. ISSN 2042-6496

Kang, Jiye, Wang, Ziwei, Cremonini, Eleonora, Gall, Gwenaelle Le ORCID: https://orcid.org/0000-0002-1379-2196, Pontifex, Matthew G. ORCID: https://orcid.org/0000-0003-2174-2313, Muller, Michael ORCID: https://orcid.org/0000-0002-5930-9905, Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756 and Oteiza, Patricia I. (2022) (-)-Epicatechin mitigates anxiety-related behavior in a mouse model of high fat diet-induced obesity. Journal of Nutritional Biochemistry, 110. ISSN 0955-2863

Cortez, Natalia E., Rodriguez Lanzi, Cecilia, Hong, Brian V., Xu, Jihao, Wang, Fangyi, Chen, Shuai, Ramsey, Jon J., Pontifex, Matthew G. ORCID: https://orcid.org/0000-0003-2174-2313, Müller, Michael ORCID: https://orcid.org/0000-0002-5930-9905, Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756, Vahmani, Payam, Hwang, Chang-Il, Matsukuma, Karen and Mackenzie, Gerardo G. (2022) A ketogenic diet in combination with gemcitabine increases survival in pancreatic cancer KPC mice. Cancer Research Communications, 2 (9). 951–965. ISSN 2767-9764

Connell, Emily, Le Gall, Gwenaelle ORCID: https://orcid.org/0000-0002-1379-2196, Pontifex, Matthew G. ORCID: https://orcid.org/0000-0003-2174-2313, Sami, Saber, Cryan, John F., Clarke, Gerard, Müller, Michael ORCID: https://orcid.org/0000-0002-5930-9905 and Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756 (2022) Microbial-derived metabolites as a risk factor of age-related cognitive decline and dementia. Molecular Neurodegeneration, 17 (1). ISSN 1750-1326

Flanagan, Emma, Cameron, Donnie ORCID: https://orcid.org/0000-0001-9841-6909, Sobhan, Rashed, Wong, Chloe, Pontifex, Matthew G. ORCID: https://orcid.org/0000-0003-2174-2313, Tosi, Nicole, Mena, Pedro, Del Rio, Daniele, Sami, Saber, Narbad, Arjan, Müller, Michael ORCID: https://orcid.org/0000-0002-5930-9905, Hornberger, Michael ORCID: https://orcid.org/0000-0002-2214-3788 and Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756 (2022) Chronic consumption of cranberries (Vaccinium macrocarpon) for 12 weeks improves episodic memory and regional brain perfusion in healthy older adults: A randomised, placebo-controlled, parallel-groups feasibility study. Frontiers in Nutrition, 9. ISSN 2296-861X

Pontifex, Matthew G. ORCID: https://orcid.org/0000-0003-2174-2313, Martinsen, Anneloes, Saleh, Rasha N. M., Harden, Glenn, Fox, Chris ORCID: https://orcid.org/0000-0001-9480-5704, Muller, Michael ORCID: https://orcid.org/0000-0002-5930-9905, Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756 and Minihane, Anne-Marie ORCID: https://orcid.org/0000-0001-9042-4226 (2022) DHA-enriched fish oil ameliorates deficits in cognition associated with menopause and the APOE4 genotype in rodents. Nutrients, 14 (9). ISSN 2072-6643

Coletto, Erika, Latousakis, Dimitrios, Pontifex, Matthew G. ORCID: https://orcid.org/0000-0003-2174-2313, Crost, Emmanuelle H., Vaux, Laura, Perez Santamarina, Estella, Goldson, Andrew, Brion, Arlaine, Hajihosseini, Mohammad K., Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756, Savva, George M. and Juge, Nathalie (2022) The role of the mucin-glycan foraging Ruminococcus gnavus in the communication between the gut and the brain. Gut Microbes, 14 (1). ISSN 1949-0976

Parker, Aimée, Romano, Stefano, Ansorge, Rebecca, Aboelnour, Asmaa, Le Gall, Gwenaelle ORCID: https://orcid.org/0000-0002-1379-2196, Savva, George M., Pontifex, Matthew G. ORCID: https://orcid.org/0000-0003-2174-2313, Telatin, Andrea, Baker, David, Jones, Emily, Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756, Rudder, Steven, Blackshaw, L. Ashley, Jeffery, Glen and Carding, Simon R. (2022) Fecal microbiota transfer between young and aged mice reverses hallmarks of the aging gut, eye, and brain. Microbiome, 10. ISSN 2049-2618

Swingler, Tracey E., Niu, Lingzi, Pontifex, Matthew G. ORCID: https://orcid.org/0000-0003-2174-2313, Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756 and Clark, Ian M. (2022) The microRNA-455 null mouse has memory deficit and increased anxiety, targeting key genes involved in Alzheimer’s disease. International Journal of Molecular Sciences, 23 (1). ISSN 1661-6596

Pontifex, Matthew G. ORCID: https://orcid.org/0000-0003-2174-2313, Mushtaq, Aleena, Le Gall, Gwenaëlle ORCID: https://orcid.org/0000-0002-1379-2196, Rodriguez-Ramiro, Ildefonso, Blokker, Britt Anne, Hoogteijling, Mara E. M., Ricci, Matthew, Pellizzon, Michael, Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756 and Müller, Michael ORCID: https://orcid.org/0000-0002-5930-9905 (2021) Differential influence of soluble dietary fibres on iIntestinal and hepatic carbohydrate response. Nutrients, 13 (12). ISSN 2072-6643

Hoyles, Lesley, Pontifex, Matthew G. ORCID: https://orcid.org/0000-0003-2174-2313, Rodriguez-Ramiro, Ildefonso, Anis-Alavi, M. Areeb, Jelane, Khadija S., Snelling, Tom, Solito, Egle, Fonseca, Sonia, Carvalho, Ana L., Carding, Simon R., Müller, Michael ORCID: https://orcid.org/0000-0002-5930-9905, Glen, Robert C., Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756 and McArthur, Simon (2021) Regulation of blood–brain barrier integrity by microbiome-associated methylamines and cognition by trimethylamine N-oxide. Microbiome, 9 (1). ISSN 2049-2618

Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756, Rendeiro, Catarina, D'Amato, Alfonsina, Waffo-Téguo, Pierre, Richard, Tristan, Mérillon, Jean Michel, Pontifex, Matthew G. ORCID: https://orcid.org/0000-0003-2174-2313, Connell, Emily, Müller, Michael ORCID: https://orcid.org/0000-0002-5930-9905, Butler, Laurie T., Williams, Claire M. and Spencer, Jeremy P. E. (2021) Anthocyanins promote learning through modulation of synaptic plasticity related proteins in an animal model of ageing. Antioxidants, 10 (8). ISSN 2076-3921

Pontifex, Matthew G. ORCID: https://orcid.org/0000-0003-2174-2313, Martinsen, Anneloes, Saleh, Rasha Noureldin M., Harden, Glenn, Tejera, Noemi, Müller, Michael ORCID: https://orcid.org/0000-0002-5930-9905, Fox, Chris ORCID: https://orcid.org/0000-0001-9480-5704, Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756 and Minihane, Anne‐Marie ORCID: https://orcid.org/0000-0001-9042-4226 (2021) APOE4 genotype exacerbates the impact of menopause on cognition and synaptic plasticity in APOE-TR mice. The FASEB Journal, 35 (5). ISSN 0892-6638

Pontifex, Matthew G. ORCID: https://orcid.org/0000-0003-2174-2313, Malik, Mohammad M. A. H., Connell, Emily, Müller, Michael ORCID: https://orcid.org/0000-0002-5930-9905 and Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756 (2021) Citrus polyphenols in brain health and disease: Current perspectives. Frontiers in Neuroscience, 15. ISSN 1662-4548

Wong, Shi Quan, Pontifex, Matthew G ORCID: https://orcid.org/0000-0003-2174-2313, Phelan, Marie M, Pidathala, Chandra, Kraemer, Brian C, Barclay, Jeff W, Berry, Neil G, O'Neill, Paul M, Burgoyne, Robert D and Morgan, Alan (2018) α-Methyl-α-phenylsuccinimide ameliorates neurodegeneration in a C. elegans model of TDP-43 proteinopathy. Neurobiology of Disease, 118. pp. 40-54. ISSN 0969-9961

Pontifex, Matthew ORCID: https://orcid.org/0000-0003-2174-2313, Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756 and Minihane, Anne-Marie ORCID: https://orcid.org/0000-0001-9042-4226 (2018) The effect of APOE genotype on Alzheimer’s disease risk is influenced by sex and DHA status. Neurobiology of Aging, 69. pp. 209-220. ISSN 0197-4580

Book Section

Connell, Emily, Pontifex, Matthew ORCID: https://orcid.org/0000-0003-2174-2313 and Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756 (2023) Nutrition and the Ageing Brain. In: Evidence-based Functional Foods for Prevention of Age-related Diseases. Springer Nature, pp. 81-100. ISBN 9789819905348

Conference or Workshop Item

Saleh, Rasha, Hornberger, Michael ORCID: https://orcid.org/0000-0002-2214-3788, Pontifex, Matthew ORCID: https://orcid.org/0000-0003-2174-2313, Vauzour, David ORCID: https://orcid.org/0000-0001-5952-8756, Ritchie, Craig and Minihane, Anne-Marie ORCID: https://orcid.org/0000-0001-9042-4226 (2023) The effect of APOEƐ4 on neurocognitive decline is accentuated by female sex and menopause: Identification of mitigating interventions. In: UNSPECIFIED.