Cominetti, Marco M. D., Goddard, Zoë R. ORCID: https://orcid.org/0000-0002-7900-1553, Hood, Bethany R., Beekman, Andrew M.
ORCID: https://orcid.org/0000-0002-3056-6406, O'Connell, Maria A.
ORCID: https://orcid.org/0000-0002-0267-0951 and Searcey, Mark
ORCID: https://orcid.org/0000-0003-2273-8949
(2024)
Borylation via iridium catalysed C–H activation: a new concise route to duocarmycin derivatives.
Organic & Biomolecular Chemistry, 22 (27).
pp. 5603-5607.
ISSN 1477-0520
Hayward, Deanne, Goddard, Zoë R. ORCID: https://orcid.org/0000-0002-7900-1553, Cominetti, Marco M. D., Searcey, Mark
ORCID: https://orcid.org/0000-0003-2273-8949 and Beekman, Andrew M.
ORCID: https://orcid.org/0000-0002-3056-6406
(2024)
Light-activated azobenzene peptide inhibitor of the PD-1/PD-L1 interaction.
Chemical Communications.
ISSN 1359-7345
Hamshaw, Isabel ORCID: https://orcid.org/0000-0001-6445-0738, Cominetti, Marco M. D., Lai, Wing-Yee, Searcey, Mark
ORCID: https://orcid.org/0000-0003-2273-8949 and Mueller, Anja
ORCID: https://orcid.org/0000-0003-0774-0434
(2023)
The development of potent, competitive CXCR4 antagonists for the prevention of cancer metastasis.
Biochemical Pharmacology, 218.
ISSN 0006-2952
Ivens, Eleanor, Cominetti, Marco M. D. and Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949
(2022)
Junctions in DNA: underexplored targets for therapeutic intervention.
Bioorganic & Medicinal Chemistry, 69.
ISSN 0968-0896
Bidula, Stefan ORCID: https://orcid.org/0000-0002-3790-7138, Nadzirin, Izzuddin Bin, Cominetti, Marco, Hickey, Harry, Cullum, Sean A., Searcey, Mark
ORCID: https://orcid.org/0000-0003-2273-8949, Schmid, Ralf and Fountain, Samuel J.
ORCID: https://orcid.org/0000-0002-6028-0548
(2022)
Structural basis of the negative allosteric modulation of 5-BDBD at human P2X4 receptors.
Molecular Pharmacology, 101 (1).
pp. 33-44.
ISSN 1521-0111
M. M. D. Cominetti, Marco, Goddard, Zoë R. ORCID: https://orcid.org/0000-0002-7900-1553, Howman, Chloe E., O'Connell, Maria A.
ORCID: https://orcid.org/0000-0002-0267-0951 and Searcey, Mark
ORCID: https://orcid.org/0000-0003-2273-8949
(2021)
Amino DSA analogues as payloads for antibody-drug conjugates with multiple sites for conjugation. Initial studies and solid phase synthesis.
Tetrahedron Letters, 72.
ISSN 0040-4039
Goddard, Zoë Rachael ORCID: https://orcid.org/0000-0002-7900-1553, Beekman, Andrew Michael
ORCID: https://orcid.org/0000-0002-3056-6406, Cominetti, Marco M. D., O'Connell, Maria A.
ORCID: https://orcid.org/0000-0002-0267-0951, Chambrier, Isabelle, Cook, Michael J., Marin, Maria J.
ORCID: https://orcid.org/0000-0001-8021-5498, Russell, David A. and Searcey, Mark
ORCID: https://orcid.org/0000-0003-2273-8949
(2021)
Peptide directed phthalocyanine-gold nanoparticles for selective photodynamic therapy of EGFR overexpressing cancers.
RSC Medicinal Chemistry, 12 (2).
pp. 288-292.
ISSN 2632-8682
Cartwright, Oliver Charles, Beekman, Andrew Michael ORCID: https://orcid.org/0000-0002-3056-6406, Cominetti, Marco M. D., Russell, David A. and Searcey, Mark
ORCID: https://orcid.org/0000-0003-2273-8949
(2020)
A peptide-duocarmycin conjugate targeting the Thomsen-Friedenreich antigen has potent and selective antitumour activity.
Bioconjugate Chemistry, 31 (7).
1745–1749.
ISSN 1043-1802
Beekman, Andrew ORCID: https://orcid.org/0000-0002-3056-6406, Cominetti, Marco, Cartwright, Oliver, Boger, Dale L. and Searcey, Mark
ORCID: https://orcid.org/0000-0003-2273-8949
(2019)
A small molecule drug conjugate (SMDC) of DUPA and a duocarmycin built on the solid phase.
MedChemComm, 10 (12).
pp. 2170-2174.
ISSN 2040-2503
Beekman, Andrew M. ORCID: https://orcid.org/0000-0002-3056-6406, Cominetti, Marco M. D., Walpole, Samuel J., Prabhu, Saurabh, O'Connell, Maria A.
ORCID: https://orcid.org/0000-0002-0267-0951, Angulo Alvarez, Jesus
ORCID: https://orcid.org/0000-0001-7250-5639 and Searcey, Mark
ORCID: https://orcid.org/0000-0003-2273-8949
(2019)
Identification of selective protein-protein interaction inhibitors using efficient in silico peptide-directed ligand design.
Chemical Science, 10 (16).
pp. 4502-4508.
ISSN 2041-6520
Bertrand, Benoît, Fernandez-Cestau, Julio, Angulo, Jesus ORCID: https://orcid.org/0000-0001-7250-5639, Cominetti, Marco M. D., Waller, Zoe A. E., Searcey, Mark
ORCID: https://orcid.org/0000-0003-2273-8949, O'Connell, Maria A.
ORCID: https://orcid.org/0000-0002-0267-0951 and Bochmann, Manfred
ORCID: https://orcid.org/0000-0001-7736-5428
(2017)
Cytotoxicity of pyrazine-based cyclometalated (C^Npz^C)Au(III) carbene complexes: Impact of the nature of the ancillary ligand on the biological properties.
Inorganic Chemistry, 56 (10).
5728–5740.
ISSN 0020-1669
Cominetti, Marco M. D., Hughes, David L. and Matthews, Susan E. ORCID: https://orcid.org/0000-0001-8821-0851
(2016)
Open-resorcinarenes, a new family of multivalent scaffolds.
Organic & Biomolecular Chemistry, 14 (43).
pp. 10161-10164.
ISSN 1477-0520
Cominetti, Marco, Goffin, Sarah, Raffel, Ewan, Turner, Kerrie, Ramoutar, Jordann, O'Connell, Maria ORCID: https://orcid.org/0000-0002-0267-0951, Howell, Lesley and Searcey, Mark
ORCID: https://orcid.org/0000-0003-2273-8949
(2015)
Identification of a new p53/MDM2 inhibitor motif inspired by studies of chlorofusin.
Bioorganic & Medicinal Chemistry Letters, 25 (21).
pp. 4878-4880.
ISSN 0960-894X
Pergolizzi, Giulia, Cominetti, Marco, Butt, Julea N. ORCID: https://orcid.org/0000-0002-9624-5226, Field, Robert A., Bowater, Richard
ORCID: https://orcid.org/0000-0002-2745-7807 and Wagner, Gerd K.
(2015)
Base-modified NAD and AMP derivatives and their activity against bacterial DNA ligases.
Organic & Biomolecular Chemistry, 13.
pp. 6380-6398.
ISSN 1477-0520
Beekman, Andrew ORCID: https://orcid.org/0000-0002-3056-6406, Cominetti, Marco M D and Searcey, Mark
ORCID: https://orcid.org/0000-0003-2273-8949
(2019)
Duocarmycins as Antibody–Drug Conjugate (ADC) Payloads.
In:
Cytotoxic Payloads for Antibody-Drug Conjugates.
Royal Society of Chemistry.
ISBN 978-1-78801-077-1