Items where Author is "Pshezhetskiy, Dmitry"

Pchejetski, Dmitri, Hunter, Ewan, Dezfouli, Mehrnoush, Salter, Matthew, Powell, Ryan, Green, Jayne, Naithani, Tarun, Koutsothanasi, Christina, Alshaker, Heba, Jaipuria, Jiten, Connor, Martin J., Eldred-Evans, David, Fiorentino, Francesca, Ahmed, Hashim, Akoulitchev, Alexandre and Winkler, Mathias (2023) Circulating chromosome conformation signatures significantly enhance PSA positive predicting value and overall accuracy for prostate cancer detection. Cancers, 15 (3). ISSN 2072-6694

Alshaker, Heba, Hunter, Ewan, Salter, Matthew, Ramadass, Aroul, Westra, Willem, Winkler, Mathias, Green, Jayne, Akoulitchev, Alexandre and Pchejetski, Dmitri (2022) Monocytes acquire prostate cancer specific chromatin conformations upon indirect co-culture with prostate cancer cells. Frontiers in Oncology, 12. ISSN 2234-943X

Ncube, Njabulo, Kulinskaya, Elena, Steel, Nicholas ORCID: https://orcid.org/0000-0003-1528-140X and Pchejetski, Dmitry (2022) On the survival of individuals diagnosed with type 2 diabetes mellitus in the United Kingdom: A retrospective matched cohort study. Diabetes Epidemiology and Management, 6. ISSN 2666-9706

Alshaker, Heba, Mills, Robert, Hunter, Ewan, Salter, Matthew, Ramadass, Aroul, Skinner, Benjamin Matthew, Westra, Willem, Green, Jayne, Akoulitchev, Alexandre, Winkler, Mathias and Pchejetski, Dmitri (2021) Chromatin conformation changes in peripheral blood can detect prostate cancer and stratify disease risk groups. Journal of Translational Medicine, 19 (1). ISSN 1479-5876

Pchejetski, Dmitri, Alshaker, Heba, Babovic, Radomir and Maw, Kyaw (2021) A case of severe dry eye disease with corneal melting as presenting complaint of acute myeloid leukaemia. SAGE Open Medical Case Reports, 9. ISSN 2050-313X

Begun, Alexander, MacGregor, Alexander J. ORCID: https://orcid.org/0000-0003-2163-2325, Pchejetski, Dmitri and Kulinskaya, Elena (2020) Dynamic early identification of hip replacement implants with high revision rates. Study based on the NJR data from UK during 2004-2012. PLoS One, 15 (8). ISSN 1932-6203

Alshaker, Heba, Thrower, Hannah and Pchejetski, Dmitri (2020) Sphingosine kinase 1 in breast cancer: A new molecular marker and a therapy target. Frontiers in Oncology, 10. ISSN 2234-943X

Pchejetski, Dmitri, Kenbaz, Mojiba, Alshaker, Heba and Jesudason, Kiruparajan (2020) Bradycardia and syncope as sole manifestations of a cranial lesion: a case report. Journal of Medical Case Reports, 14 (1). ISSN 1752-1947

Alshaker, Heba, Wang, Qi, Brewer, Daniel ORCID: https://orcid.org/0000-0003-4753-9794 and Pshezhetskiy, Dmitry (2019) Transcriptome-wide effects of sphingosine kinases knockdown in metastatic prostate and breast cancer cells: Implications for therapeutic targeting. Frontiers in Pharmacology, 10. ISSN 1663-9812

Alshaker, Heba, Srivats, Shyam, Monteil, Danielle, Wang, Qi, Low, Caroline M. R. and Pchejetski, Dmitri (2018) Field template-based design and biological evaluation of new sphingosine kinase 1 inhibitors. Breast Cancer Research and Treatment, 172 (1). 33–43. ISSN 0167-6806

Alshaker, Heba, Wang, Qi, Srivats, Shyam, Chao, Yimin ORCID: https://orcid.org/0000-0002-8488-2690, Cooper, Colin ORCID: https://orcid.org/0000-0003-2013-8042 and Pchejetski, Dmitri (2017) New FTY720-docetaxel nanoparticle therapy overcomes FTY720-induced lymphopenia and inhibits metastatic breast tumour growth. Breast Cancer Research and Treatment, 165 (3). 531–543. ISSN 0167-6806

Wang, Qi, Alshaker, Heba, Böhler, Torsten, Srivats, Shyam, Chao, Yimin ORCID: https://orcid.org/0000-0002-8488-2690, Cooper, Colin ORCID: https://orcid.org/0000-0003-2013-8042 and Pchejetski, Dmitri (2017) Core shell lipid-polymer hybrid nanoparticles with combined docetaxel and molecular targeted therapy for the treatment of metastatic prostate cancer. Scientific Reports, 7. ISSN 2045-2322

Alshaker, Heba, Wang, Qi, Böhler, Torsten, Mills, Robert, Winkler, Mathias, Arafat, Tawfiq, Kawano, Yoshiaki and Pchejetski, Dmitri (2017) Combination of RAD001 (everolimus) and docetaxel reduces prostate and breast cancer cell VEGF production and tumour vascularisation independently of sphingosine-kinase-1. Scientific Reports, 7. ISSN 2045-2322

Pchejetski, Dmitri, Kenbaz, Mojiba, Alshaker, Heba, Rajput, Dharmesh and Jesudason, Kiruparajan (2017) An unusual case of disseminated intravascular coagulation. Oxford Medical Case Reports, 2017 (4).

Alshaker, Heba, Wang, Qi, Kawano, Yoshiaki, Arafat, Tawfiq, Böhler, Torsten, Winkler, Mathias, Cooper, Colin ORCID: https://orcid.org/0000-0003-2013-8042 and Pchejetski, Dmitri (2016) Everolimus (RAD001) sensitizes prostate cancer cells to docetaxel by down-regulation of HIF-1α and sphingosine kinase 1. Oncotarget, 7 (49). pp. 80943-80956. ISSN 1949-2553

Pchejetski, Dmitri, Alfraidi, Albandri, Sacco, Keith, Alshaker, Heba, Muhammad, Aun and Monzon, Leonardo (2016) Histone deacetylases as new therapy targets for platinum-resistant epithelial ovarian cancer. Journal of Cancer Research and Clinical Oncology, 142 (8). 1659–1671. ISSN 1432-1335

Sacco, Keith, Muhammad, Aun, Saleem, Waqar, Alshaker, Heba, Monzon, Leonardo, Islam, Mohammad Rafiqul and Pchejetski, Dmitri (2016) Leptomeningeal carcinomatosis as the primary presentation of relapse in breast cancer. Oncology Letters, 12 (2). pp. 779-782. ISSN 1792-1074

Pardo, Olivier E, Castellano, Leandro, Munro, Catriona E, Hu, Yili, Mauri, Francesco, Krell, Jonathan, Lara, Romain, Pinho, Filipa G, Choudhury, Thameenah, Frampton, Adam E, Pellegrino, Loredana, Pshezhetskiy, Dmitry, Wang, Yulan, Waxman, Jonathan, Seckl, Michael J and Stebbing, Justin (2016) miR-515-5p controls cancer cell migration through MARK4 regulation. EMBO Reports, 17 (4). pp. 570-584. ISSN 1469-221X

White, Christopher, Alshaker, Heba, Cooper, Colin ORCID: https://orcid.org/0000-0003-2013-8042, Winkler, Matthias and Pchejetski, Dmitri (2016) The emerging role of FTY720 (Fingolimod) in cancer treatment. Oncotarget, 7 (17). pp. 23106-23127. ISSN 1949-2553

Alshaker, Heba, Sacco, Keith, Alfraidi, Albandri, Muhammad, Aun, Winkler, Mathias and Pchejetski, Dmitri (2015) Leptin signalling, obesity and prostate cancer: molecular and clinical perspective on the old dilemma. Oncotarget, 6 (34). pp. 35556-35563. ISSN 1949-2553

Alshaker, Heba, Wang, Qi, Frampton, Adam E., Krell, Jonathan, Waxman, Jonathan, Winkler, Mathias, Stebbing, Justin, Cooper, Colin ORCID: https://orcid.org/0000-0003-2013-8042, Yaguee, Ernesto and Pchejetski, Dmitri (2015) Sphingosine kinase 1 contributes to leptin-induced STAT3 phosphorylation through IL-6/gp130 transactivation in oestrogen receptor-negative breast cancer. Breast Cancer Research and Treatment, 149 (1). pp. 59-67. ISSN 1573-7217

Alshaker, Heba, Krell, Jonathan, Frampton, Adam E., Wang, Qi, Cooper, Colin ORCID: https://orcid.org/0000-0003-2013-8042, Winkler, Mathias, Yaguee, Ernesto, Pchejetski, Dmitri and Alshaker, Heba (2015) Leptin receptor-dependent and -independent STAT3 phosphorylation in oestrogen receptor-negative breast cancer. International Journal of Molecular Medicine, 36. S6. ISSN 1107-3756

Alshaker, Heba, Krell, Jonathan, Frampton, Adam E., Waxman, Jonathan, Blyuss, Oleg, Zaikin, Alexey, Winkler, Mathias, Stebbing, Justin, Yaguee, Ernesto and Pchejetski, Dmitri (2014) Leptin induces upregulation of sphingosine kinase 1 in oestrogen receptor-negative breast cancer via Src family kinase-mediated, janus kinase 2-independent pathway. Breast Cancer Research, 16. ISSN 1465-542X

Annels, N E, Simpson, G R, Denyer, M, McGrath, S E, Falgari, G, Killick, E, Eeles, R, Stebbing, J, Pchejetski, D, Cutress, R, Murray, N ORCID: https://orcid.org/0000-0002-3514-5950, Michael, A and Pandha, H (2014) Spontaneous antibodies against Engrailed-2 (EN2) protein in patients with prostate cancer. Clinical and Experimental Immunology, 177 (2). pp. 428-438. ISSN 1365-2249

Pshezhetskiy, Dmitry, Alshaker, Heba and Stebbing, Justin (2014) Castrate-resistant prostate cancer: the future of antiandrogens. Trends in Urology & Men’s Health, 5 (1). ISSN 2044-3749

Alshaker, Heba, Sauer, Lysann, Monteil, Danielle, Ottaviani, Silvia, Srivats, Shyam, Böhler, Torsten and Pchejetski, Dmitri (2013) Chapter Six – Therapeutic Potential of Targeting SK1 in Human Cancers. In: Advances in Cancer Research. Advances in Cancer Research, 117 . Elsevier, pp. 143-200. ISBN 978-0-12-394274-6

Gibbs, Bernhard F, Yasinska, Inna M, Pchejetski, Dmitri, Wyszynski, Rafal W and Sumbayev, Vadim V (2012) Differential control of hypoxia-inducible factor 1 activity during pro-inflammatory reactions of human haematopoietic cells of myeloid lineage. International Journal of Biochemistry & Cell Biology, 44 (11). pp. 1739-49. ISSN 1357-2725

Pchejetski, Dmitri, Foussal, Camille, Alfarano, Chiara, Lairez, Olivier, Calise, Denis, Guilbeau-Frugier, Celine, Schaak, Stéphane, Seguelas, Marie-Hélène, Wanecq, Estelle, Valet, Philippe, Parini, Angelo and Kunduzova, Oksana (2012) Apelin prevents cardiac fibroblast activation and collagen production through inhibition of sphingosine kinase 1. European Heart Journal, 33 (18). pp. 2360-9. ISSN 0195-668X

Caley, Matthew P, Kogianni, Giolanta, Adamarek, Adam, Gronau, Julian H, Rodriguez-Teja, Mercedes, Fonseca, Ana-Violeta, Mauri, Francesco, Sandison, Ann, Rhim, Johng S, Pchejetski, Dmitri, Palmieri, Carlo, Cobb, Justin P, Waxman, Jonathan and Sturge, Justin (2012) TGFβ1-Endo180-dependent collagen deposition is dysregulated at the tumour-stromal interface in bone metastasis. The Journal of Pathology, 226 (5). pp. 775-783. ISSN 0022-3417

Stebbing, J, Sharma, A, North, B, Athersuch, T J, Zebrowski, A, Pchejetski, D, Coombes, R C, Nicholson, J K and Keun, H C (2012) A metabolic phenotyping approach to understanding relationships between metabolic syndrome and breast tumour responses to chemotherapy. Annals of Oncology, 23 (4). pp. 860-866. ISSN 0923-7534

Nunes, J, Naymark, M, Sauer, L, Muhammad, A, Keun, H, Sturge, J, Stebbing, J, Waxman, J and Pchejetski, D (2012) Circulating sphingosine-1-phosphate and erythrocyte sphingosine kinase-1 activity as novel biomarkers for early prostate cancer detection. British Journal of Cancer, 106 (5). pp. 909-915. ISSN 0007-0920

Pchejetski, Dmitri, Böhler, Torsten, Stebbing, Justin and Waxman, Jonathan (2011) Therapeutic potential of targeting sphingosine kinase 1 in prostate cancer. Nature Reviews Urology, 8 (10). pp. 569-578. ISSN 1759-4820

Pchejetski, Dmitri, Nunes, Joao, Coughlan, Karen, Lall, Harjinder, Pitson, Stuart M, Waxman, Jonathan and Sumbayev, Vadim V (2011) The involvement of sphingosine kinase 1 in LPS-induced Toll-like receptor 4-mediated accumulation of HIF-1α protein, activation of ASK1 and production of the pro-inflammatory cytokine IL-6. Immunology and Cell Biology, 89 (2). pp. 268-74. ISSN 1440-1711

Malavaud, Bernard, Pchejetski, Dmitry, Mazerolles, Catherine, de Paiva, Geisilène Russano, Calvet, Cyril, Doumerc, Nicolas, Pitson, Stuart, Rischmann, Pascal and Cuvillier, Olivier (2010) Sphingosine kinase-1 activity and expression in human prostate cancer resection specimens. European Journal of Cancer, 46 (18). pp. 3417-24. ISSN 1879-0852

Pchejetski, Dmitri, Bohler, Torsten, Brizuela, Leyre, Sauer, Lysann, Doumerc, Nicolas, Golzio, Muriel, Salunkhe, Vishal, Teissié, Justin, Malavaud, Bernard, Waxman, Jonathan and Cuvillier, Olivier (2010) FTY720 (fingolimod) sensitizes prostate cancer cells to radiotherapy by inhibition of sphingosine kinase-1. Cancer Research, 70 (21). pp. 8651-61. ISSN 0008-5472

Pchejetski, Dmitri, Nunes, Joao, Sauer, Lysann, Sidhu, Jasmin, Sharma, Anand, Keun, Hector C, Waxman, Jonathan and Stebbing, Justin (2010) Circulating sphingosine-1-phosphate inversely correlates with chemotherapy-induced weight gain during early breast cancer. Breast Cancer Research and Treatment, 124 (2). pp. 543-9. ISSN 1573-7217

Makis, Alexandros, Shipway, David, Hatzimichael, Eleftheria, Galanakis, Emmanouil, Pshezhetskiy, Dmitry, Chaliasos, Nikolaos, Stebbing, Justin and Siamopoulou, Antigone (2010) Cytokine and Adhesion Molecule Expression Evolves Between the Neutrophilic and Lymphocytic Phases of Viral Meningitis. Journal of Interferon & Cytokine Research, 30 (9). pp. 661-665. ISSN 1079-9907

Henry, N. L., Pchejetski, D., A'Hern, R., Nguyen, A. T., Charles, P., Waxman, J., Li, L., Storniolo, A. M., Hayes, D. F., Flockhart, D. A., Stearns, V. and Stebbing, J. (2010) Inflammatory cytokines and aromatase inhibitor-associated musculoskeletal syndrome: A case-control study. British Journal of Cancer, 103 (3). pp. 291-296. ISSN 0007-0920

Sauer, Lysann, Nunes, Joao, Salunkhe, Vishal, Skalska, Lenka, Kohama, Takafumi, Cuvillier, Olivier, Waxman, Jonathan and Pchejetski, Dmitry (2009) Sphingosine kinase 1 inhibition sensitizes hormone-resistant prostate cancer to docetaxel. International Journal of Cancer, 125 (11). pp. 2728-36.

Keun, Hector C, Sidhu, Jasmin, Pchejetski, Dmitry, Lewis, Jacqueline S, Marconell, Helena, Patterson, Michael, Bloom, Steven R, Amber, Vian, Coombes, R Charles and Stebbing, Justin (2009) Serum molecular signatures of weight change during early breast cancer chemotherapy. Clinical Cancer Research, 15 (21). pp. 6716-23. ISSN 1078-0432

Guillermet-Guibert, Julie, Davenne, Lise, Pchejetski, Dmitry, Saint-Laurent, Nathalie, Brizuela, Leyre, Guilbeau-Frugier, Céline, Delisle, Marie-Bernadette, Cuvillier, Olivier, Susini, Christiane and Bousquet, Corinne (2009) Targeting the sphingolipid metabolism to defeat pancreatic cancer cell resistance to the chemotherapeutic gemcitabine drug. Molecular Cancer Therapeutics, 8 (4). pp. 809-20. ISSN 1535-7163

Pchejetski, Dmitry, Doumerc, Nicolas, Golzio, Muriel, Naymark, Maria, Teissié, Justin, Kohama, Takafumi, Waxman, Jonathan, Malavaud, Bernard and Cuvillier, Olivier (2008) Chemosensitizing effects of sphingosine kinase-1 inhibition in prostate cancer cell and animal models. Molecular Cancer Therapeutics, 7 (7). pp. 1836-45. ISSN 1535-7163

Gomez-Brouchet, Anne, Pchejetski, Dmitry, Brizuela, Leyre, Garcia, Virginie, Altié, Marie-Françoise, Maddelein, Marie-Lise, Delisle, Marie-Bernadette and Cuvillier, Olivier (2007) Critical role for sphingosine kinase-1 in regulating survival of neuroblastoma cells exposed to amyloid-beta peptide. Molecular Pharmacology, 72 (2). pp. 341-9. ISSN 0026-895X

Pchejetski, Dmitry, Kunduzova, Oxana, Dayon, Audrey, Calise, Denis, Seguelas, Marie-Hélène, Leducq, Nathalie, Seif, Isabelle, Parini, Angelo and Cuvillier, Olivier (2007) Oxidative stress-dependent sphingosine kinase-1 inhibition mediates monoamine oxidase A-associated cardiac cell apoptosis. Circulation Research, 100 (1). pp. 41-9. ISSN 0009-7330

Akimova, Olga A, Pchejetski, Dmitry, Hamet, Pavel and Orlov, Sergei N (2006) Modest intracellular acidification suppresses death signaling in ouabain-treated cells. Pflügers Archiv European Journal of Physiology, 451 (4). pp. 569-78. ISSN 0031-6768

Bonhoure, E, Pchejetski, D, Aouali, N, Morjani, H, Levade, T, Kohama, T and Cuvillier, O (2006) Overcoming MDR-associated chemoresistance in HL-60 acute myeloid leukemia cells by targeting sphingosine kinase-1. Leukemia, 20 (1). pp. 95-102. ISSN 0887-6924

Pchejetski, Dmitry, Golzio, Muriel, Bonhoure, Elisabeth, Calvet, Cyril, Doumerc, Nicolas, Garcia, Virginie, Mazerolles, Catherine, Rischmann, Pascal, Teissié, Justin, Malavaud, Bernard and Cuvillier, Olivier (2005) Sphingosine kinase-1 as a chemotherapy sensor in prostate adenocarcinoma cell and mouse models. Cancer Research, 65 (24). pp. 11667-75. ISSN 0008-5472

Le Scolan, Erwan, Pchejetski, Dmitry, Banno, Yoshiko, Denis, Nicole, Mayeux, Patrick, Vainchenker, William, Levade, Thierry and Moreau-Gachelin, Françoise (2005) Overexpression of sphingosine kinase 1 is an oncogenic event in erythroleukemic progression. Blood, 106 (5). pp. 1808-16. ISSN 0006-4971

Orlov, Sergei N, Thorin-Trescases, Nathalie, Pchejetski, Dmitry, Taurin, Sebastien, Farhat, Nada, Tremblay, Johanne, Thorin, Eric and Hamet, Pavel (2004) Na+/K+ pump and endothelial cell survival: [Na+]i/[K+]i-independent necrosis triggered by ouabain, and protection against apoptosis mediated by elevation of [Na+]i. Pflügers Archiv European Journal of Physiology, 448 (3). pp. 335-45. ISSN 0031-6768

Orlov, S. N., Pchejetski, D., Taurin, S., Thorin-Trescases, N., Maximov, G. V., Pshezhetsky, A. V., Rubin, A. B. and Hamet, P. (2004) Apoptosis in serum-deprived vascular smooth muscle cells: Evidence for cell volume-independent mechanism. Apoptosis, 9 (1). pp. 55-66. ISSN 1360-8185

Brindikova, Tatyana A, Bourcier, Nathalie, Torres, Brian, Pchejetski, Dmitry, Gekle, Michel, Maximov, Georgy V, Montminy, Valérie, Insel, Paul A, Orlov, Sergei N and Isenring, Paul (2003) Purinergic-induced signaling in C11-MDCK cells inhibits the secretory Na-K-Cl cotransporter. American Journal of Physiology - Cell Physiology, 285 (6). C1445-53. ISSN 0363-6143

Orlov, S N, Pchejetski, D V, Sarkissian, S D, Adarichev, V, Taurin, S, Pshezhetsky, A V, Tremblay, J, Maximov, G V, deBlois, D, Bennett, M R and Hamet, P (2003) [3H]-thymidine labelling of DNA triggers apoptosis potentiated by E1A-adenoviral protein. Apoptosis, 8 (2). pp. 199-208. ISSN 1360-8185

Pchejetski, Dmitry, Taurin, Sebastien, Der Sarkissian, Shant, Lopina, Olga D., Pshezhetsky, Alexei V., Tremblay, Johanne, deBlois, Denis, Hamet, Pavel and Orlov, Sergei N. (2003) Inhibition of Na+,K+-ATPase by ouabain triggers epithelial cell death independently of inversion of the [Na+]i/[K+]i ratio. Biochemical and Biophysical Research Communications, 301 (3). pp. 735-744. ISSN 0006-291X

Taurin, Sebastien, Dulin, Nickolai O., Pchejetski, Dmitry, Grygorczyk, Ryszard, Tremblay, Johanne, Hamet, Pavel and Orlov, Sergei N. (2002) c-Fos expression in ouabain-treated vascular smooth muscle cells from rat aorta: Evidence for an intracellular-sodium-mediated, calcium-independent mechanism. The Journal of Physiology, 543 (3). pp. 835-47. ISSN 0022-3751