Items where Research Group is "Synthetic and Medicinal Chemistry

Alphey, Magnus S., Pirrie, Lisa, Torrie, Leah S., Boulkeroua, Wassila Abdelli, Gardiner, Mary, Sarkar, Aurijit, Maringer, Marko, Oehlmann, Wulf, Brenk, Ruth, Scherman, Michael S., McNeil, Michael, Rejzek, Martin, Field, Robert A., Singh, Mahavir, Gray, David, Westwood, Nicholas J. and Naismith, James H. (2013) Allosteric competitive inhibitors of the glucose-1-phosphate thymidylyltransferase (RmlA) from pseudomonas aeruginosa. ACS Chemical Biology, 8 (2). pp. 387-396. ISSN 1554-8929

Bew, S.P., Ashford, P.-A. and Bachera, D.U. (2013) Synthesis of structure and function diverse α-D-diazoacetates, α-D-diazoacetamides, α-D-diazoketones, and the antibiotic α-D-azaserine. Synthesis, 45 (7). pp. 903-912. ISSN 0039-7881

Bew, Sean P., Stephenson, G. Richard, Rouden, Jacques, Martinez-Lozano, Luis A. and Seylani, Haseena (2013) Malonic acid half oxyesters and thioesters: Solvent-free synthesis and DFT analysis of their enols. Organic Letters, 15 (15). pp. 3805-3807. ISSN 1523-7060

Butler, Claire E., de Carvalho, Tecia M. U., Grisard, Edmundo C., Field, Robert A. and Tyler, Kevin (2013) Trans-sialidase stimulates eat me response from epithelial cells. Traffic, 14 (7). pp. 853-869. ISSN 1600-0854

Caputi, Lorenzo, Nepogodiev, Sergey A., Malnoy, Mickael, Rejzek, Martin, Field, Robert A. and Benini, Stefano (2013) Biomolecular characterization of the levansucrase of erwinia amylovora, a promising biocatalyst for the synthesis of fructooligosaccharides. Journal of Agricultural and Food Chemistry, 61 (50). pp. 12265-12273. ISSN 0021-8561

Caputi, Lorenzo, Rejzek, Martin, Louveau, Thomas, O'Neill, Ellis C., Hill, Lionel, Osbourn, Anne and Field, Robert A. (2013) A one-pot enzymatic approach to the O-fluoroglucoside of N-methylanthranilate. Bioorganic and Medicinal Chemistry, 21 (16). pp. 4762-4767. ISSN 0968-0896

Chaure, Nandu B., Barard, Seema, Ray, Asim K., Cammidge, Andrew N. and Cook, Michael J. (2013) Ambipolar charge transport in non-peripherally substituted octahexyl zinc phthalocyanine. European Physical Society Letters, 104 (5). ISSN 0295-5075

Chi, Bui Khanh, Roberts, Alexandra A., Huyen, Tran Thi Thanh, Bäsell, Katrin, Becher, Dörte, Albrecht, Dirk, Hamilton, Chris J. and Antelmann, Haike (2013) S-Bacillithiolation protects conserved and essential proteins against hypochlorite stress in Firmicutes bacteria. Antioxidants & Redox Signaling, 18 (11). pp. 1273-1295. ISSN 1523-0864

Dann, Thomas, Roşca, Dragoş-adrian, Wright, Joseph A., Wildgoose, Gregory G. and Bochmann, Manfred (2013) Electrochemistry of AuII and AuIII pincer complexes: determination of the AuII–AuII bond energy. Chemical Communications, 49 (86). pp. 10169-10171. ISSN 1359-7345

Díaz-Moscoso, Alejandro, Tizzard, Graham J., Coles, Simon J. and Cammidge, Andrew N. (2013) Synthesis of meso-substituted tetrabenzotriazaporphyrins: Easy access to hybrid macrocycles. Angewandte Chemie-International Edition, 52 (41). pp. 10784-10787. ISSN 1433-7851

Fang, Zhong, Roberts, Alexandra A., Weidman, Karissa, Sharma, Sunil C., Claiborne, Al, Hamilton, Christopher and Dos Santos, Patricia C. (2013) Cross functionalities of Bacillus deacetylases involved in bacillithial biosynthesis and bacillitiol-S-conjugate detoxification pathways. Biochemistry Journal, 454 (2). pp. 239-247.

Gaballa, A., Antelmann, H., Hamilton, C. J. and Helmann, J. D. (2013) Regulation of Bacillus subtilis bacillithiol biosynthesis operons by Spx. Microbiology, 159 (Pt_10). pp. 2025-2035. ISSN 1350-0872

Gopee, Hemant, Cammidge, Andrew N. and Oganesyan, Vasily S. (2013) Probing columnar discotic liquid crystals by EPR spectroscopy with a rigid-core nitroxide spin probe. Angewandte Chemie-International Edition, 52 (34). pp. 8917-8920. ISSN 1433-7851

Gopee, Hemant, Kong, Xiangfei, He, Zhiqun, Chambrier, Isabelle, Hughes, David L., Tizzard, Graham J., Coles, Simon J. and Cammidge, Andrew N. (2013) Expanded porphyrin-like structures based on twinned triphenylenes. Journal of Organic Chemistry, 78 (18). pp. 9505-9511. ISSN 0022-3263

Heeney, Martin J., Al-Raqa, Shaya A., Auger, Aurélien, Burnham, Paul M., Cammidge, Andrew N., Chambrier, Isabelle and Cook, Michael J. (2013) Routes to some 3,6-disubstituted phthalonitriles and examples of phthalocyanines derived therefrom: An overview. Journal of Porphyrins and Phthalocyanines, 17 (08n09). pp. 649-664. ISSN 1088-4246

Iqbal, Amjid, Chibli, Hicham and Hamilton, Christopher (2013) Stability of aminooxy glycosides to glycosidase catalysed hydrolysis. Carbohydrate Research, 377. pp. 1-3. ISSN 0008-6215

Marin, MJ, Rackham, Benjamin D., Round, Andrew N., Howell, Lesley A., Russell, David A. and Searcey, Mark (2013) A rapid screen for molecules that form duplex to duplex crosslinks in DNA. Chemical Communications, 49 (80). p. 9113. ISSN 1359-7345

Marin, MJ, Rashid, Abdul, Rejzek, Martin, Fairhurst, Shirley A., Wharton, Stephen A., Martin, Stephen R., Mccauley, John W., Wileman, Thomas, Field, Robert A. and Russell, David A. (2013) Glyconanoparticles for the plasmonic detection and discrimination between human and avian influenza virus. Organic & Biomolecular Chemistry, 11 (41). pp. 7101-7107. ISSN 1477-0520

Mckenzie, Iain, Cammidge, Andrew, Gopee, Hemant, Dilger, Herbert, Scheuermann, Robert, Stoykov, Alexey and Jayasooriya, Upali (2013) Muoniated spin probes in the discotic liquid crystal HHTT: Rapid electron spin relaxation in the hexagonal columnar and isotropic phases. Physical Review E, 87 (1). ISSN 1539-3755

Miah, Farzana, Koliwer-Brandl, Hendrik, Rejzek, Martin, Field, Robert A., Kalscheuer, Rainer and Bornemann, Stephen (2013) Flux through trehalose synthase flows from trehalose to the alpha anomer of maltose in mycobacteria. Chemistry and Biology, 20 (4). pp. 487-493. ISSN 1074-5521

O'Neill, Ellis C. and Field, Robert A. (2013) Antibiotics:Blocking bacterial defences. Nature Chemistry, 5 (8). pp. 642-643. ISSN 1755-4330

Owatworakit, Amorn, Townsend, Belinda, Louveau, Thomas, Jenner, Helen, Rejzek, Martin, Hughes, Richard K., Saalbach, Gerhard, Qi, Xiaoquan, Bakht, Saleha, Roy, Abhijeet Deb, Mugford, Sam T., Goss, Rebecca J. M., Field, Robert A. and Osbourn, Anne (2013) Glycosyltransferases from oat (Avena) implicated in the acylation of avenacins. Journal of Biological Chemistry, 288 (6). pp. 3696-3704. ISSN 0021-9258

Pal, C., Sharma, A. K., Cammidge, A. N., Cook, M. J. and Ray, A. K. (2013) Octaoctyl-substituted lutetium bisphthalocyanine for NADH biosensing. The Journal of Physical Chemistry B, 117 (48). 15033–15040. ISSN 1520-6106

Pöther, Dierk-Christoph, Gierok, Philipp, Harms, Manuela, Mostertz, Jörg, Hochgräfe, Falko, Antelmann, Haike, Hamilton, Christopher, Borovok, Ilya, Lalk, Michael, Aharonowitz, Yair and Hecker, Michael (2013) Distribution and infection-related functions of bacillithiol in Staphylococcus aureus. International Journal of Medical Microbiology, 303 (3). pp. 114-123. ISSN 1438-4221

Rackham, Benjamin D., Howell, Lesley A., Round, Andrew N. and Searcey, Mark (2013) Non-covalent duplex to duplex crosslinking of DNA in solution revealed by single molecule force spectroscopy. Organic & Biomolecular Chemistry, 11 (48). pp. 8340-8347. ISSN 1477-0520

Rajkarnikar, Arishma, Strankman, Andrew, Duran, Shayla, Vargas, Derek, Roberts, Alexandra A., Barretto, Kathryn, Upton, Heather, Hamilton, Christopher J. and Rawat, Mamta (2013) Analysis of mutants disrupted in bacillithiol metabolism in Staphylococcus aureus. Biochemical and Biophysical Research Communications, 436 (2). pp. 128-133. ISSN 0006-291X

Roberts, Alexandra A., Sharma, Sunil V., Strankman, Andrew W., Duran, Shayla R., Rawat, Mamta and Hamilton, Chris J. (2013) Mechanistic studies of FosB: a divalent-metal-dependent bacillithiol-S-transferase that mediates fosfomycin resistance in Staphylococcus aureus. Biochemical Journal, 451 (1). pp. 69-79. ISSN 0264-6021

Rosca, Dragos-Adrian, Wright, Joseph, Hughes, David and Bochmann, Manfred (2013) Gold peroxide complexes and the conversion of hydroperoxides into gold hybrides by successive oxygen-transfer reactions. Nature Communications, 4. ISSN 2041-1723

Ruzanski, Christian, Smirnova, Julia, Rejzek, Martin, Cockburn, Darrell, Pedersen, Henriette L., Pike, Marilyn, Willats, William G.T., Svensson, Birte, Steup, Martin, Ebenhöh, Oliver, Smith, Alison M. and Field, Robert A. (2013) A bacterial glucanotransferase can replace the complex maltose metabolism required for starch to sucrose conversion in leaves at night. Journal of Biological Chemistry, 288 (40). pp. 28581-28598. ISSN 0021-9258

Sharma, Sunil V., Arbach, Miriam, Roberts, Alexandra A., Macdonald, Colin J., Groom, Murree and Hamilton, Chris J. (2013) Biophysical features of bacillithiol, the glutathione surrogate of Bacillus subtilis and other firmicutes. ChemBioChem, 14 (16). pp. 2160-2168. ISSN 1439-4227

Sheldrake, Helen M., Travica, Sandra, Johansson, Inger, Loadman, Paul M., Sutherland, Mark, Elsalem, Lina, Illingworth, Nicola, Cresswell, Alexander J., Reuillon, Tristan, Shnyder, Steven D., Mkrtchian, Souren, Searcey, Mark, Ingelman-Sundberg, Magnus, Patterson, Laurence H. and Pors, Klaus (2013) Re-engineering of the duocarmycin structural architecture enables bioprecursor development targeting CYP1A1 and CYP2W1 for biological activity. Journal of Medicinal Chemistry, 56 (15). pp. 6273-6277. ISSN 0022-2623

Sosa-vargas, Lydia X., Chambrier, Isabelle, Macdonald, Colin J., Coles, Simon J., Tizzard, Graham J., Cammidge, Andrew N. and Cook, Michael J. (2013) Synthesis and characterization of some octaalkyl substituted lead phthalocyanines and unexpected variations in lead lability arising from the position of substituents and their chain length. Journal of Porphyrins and Phthalocyanines, 17 (06n07). pp. 511-521. ISSN 1088-4246

Sutherland, Mark, Gill, Jason H, Loadman, Paul M, Laye, Jonathan P, Sheldrake, Helen M, Illingworth, Nicola A, Alandas, Mohammed N, Cooper, Patricia A, Searcey, Mark, Pors, Klaus, Shnyder, Steve D and Patterson, Laurence H (2013) Antitumor activity of a duocarmycin analogue rationalized to be metabolically activated by cytochrome P450 1A1 in human transitional cell carcinoma of the bladder. Molecular Cancer Therapeutics, 12 (1). pp. 27-37. ISSN 1538-8514

Taylor, James A., Mitchenall, Lesley A., Rejzek, Martin, Field, Robert A. and Maxwell, Anthony (2013) Application of a Novel Microtitre Plate-Based Assay for the Discovery of New Inhibitors of DNA Gyrase and DNA Topoisomerase VI. PLoS One, 8 (2). ISSN 1932-6203

Turrell, Peter J., Hill, Amanda D., Ibrahim, Saad K., Wright, Joseph. A. and Pickett, Christopher J. (2013) Ferracyclic carbamoyl complexes related to the active site of [Fe]-hydrogenase. Dalton Transactions, 42 (22). pp. 8140-8146. ISSN 1477-9226