Items where Research Group is "Pharmacology and Biological Chemistry

B

Bidula, Stefan, Sexton, Darren W, Yates, Matthew, Abdolrasouli, Alireza, Shah, Anand, Wallis, Russell, Reed, Anna, Armstrong-James, Darius and Schelenz, Silke (2015) H-ficolin binds Aspergillus fumigatus leading to activation of the lectin complement pathway and modulation of lung epithelial immune responses. Immunology, 146 (2). pp. 281-291. ISSN 0019-2805

Bidula, Stefan, Sexton, Darren W., Abdolrasouli, Alireza, Shah, Anand, Reed, Anna, Armstrong-James, Darius and Schelenz, Silke (2015) The serum opsonin L-ficolin is detected in lungs of human transplant recipients following fungal infections and modulates inflammation and killing of Aspergillus fumigatus. Journal of Infectious Diseases, 212 (2). pp. 234-246. ISSN 0022-1899

Bradley, Justin M., Svistunenko, Dimitri A., Lawson, Tamara L., Hemmings, Andrew M., Moore, Geoffrey R. and Le Brun, Nick E. (2015) Three aromatic residues are required for electron transfer during iron mineralization in Bacterioferritin. Angewandte Chemie-International Edition, 127 (49). 14976–14980. ISSN 1433-7851

C

Codoni, Doroty, Cowan, Jonathan, Bradley, Jenna, O'Connell, Maria, McAuley, William and Qi, Sheng (2015) Disc-shaped polyoxyethylene glycol glycerides gel nanoparticles as novel protein delivery vehicles. International Journal of Pharmaceutics, 496 (2). pp. 1015-1025. ISSN 0378-5173

Cominetti, Marco, Goffin, Sarah, Raffel, Ewan, Turner, Kerrie, Ramoutar, Jordann, O'Connell, Maria, Howell, Lesley and Searcey, Mark (2015) Identification of a new p53/MDM2 inhibitor motif inspired by studies of chlorofusin. Bioorganic & Medicinal Chemistry Letters, 25 (21). pp. 4878-4880. ISSN 0960-894X

Crack, Jason, Munnoch, John Tyson, Dodd, Erin, Knowles, Felicity, Al-Bassam, Mahmoud, Kamali, Saeed, Holland, Ashley, Cramer, Stephen, Hamilton, Christopher, Johnson, Michael, Thomson, Andrew, Hutchings, Matthew and Le Brun, Nick (2015) NsrR from Streptomyces coelicolor is a nitric oxide-sensing [4Fe-4S] cluster protein with a specialized regulatory function. The Journal of Biological Chemistry, 290. pp. 12689-12704. ISSN 1083-351X

D

Dao-Ung, Phuong, Skarratt, Kristen, Fuller, Stephen and Stokes, Leanne (2015) Paroxetine suppresses recombinant human P2X7 responses. Purinergic Signalling, 11 (4). pp. 481-490. ISSN 1573-9538

Di Gesso, Jessica, Kerr, Jason, Zhang, Qingzhi, Raheem, Saki, Krishna Yalamanchili, Sai, O'Hagan, David, Kay, Colin and O'Connell, Maria (2015) Flavonoid metabolites reduce tumor necrosis factor-α secretion to a greater extent than their precursor compounds in human THP-1 monocytes. Molecular Nutrition & Food Research, 59 (6). 1143–1154. ISSN 1613-4125

H

Handley, Rebecca A, Mulholland, Francis, Reuter, Mark, Ramachandran, Vinoy K, Musk, Heather, Clissold, Leah, Le Brun, Nick E and van Vliet, Arnoud H M (2015) PerR controls oxidative stress defence and aerotolerance but not motility-associated phenotypes of Campylobacter jejuni. Microbiology, 161. pp. 1524-1536. ISSN 1350-0872

Helliwell, Ray, ShioukHuey, Charlene, Dhuna, Kshitija, Molero, Juan, Ye, Jiming, Xue, Charlie and Stokes, Leanne (2015) Selected ginsenosides of the prptopanaxdiol series are novel positive allosteric modulators of P2X7 receptors. British Journal of Pharmacology, 172 (13). pp. 3326-3340. ISSN 0007-1188

I

Ibrahim, Susan A., Crack, Jason C., Rolfe, Matthew D., Borrero-de Acuňa, Jose Manuel, Thomson, Andrew J., Le Brun, Nick E., Schobert, Max, Stapleton, Melanie R. and Green, Jeffrey (2015) Three Pseudomonas putida FNR family proteins with different sensitivities to O2. The Journal of Biological Chemistry, 290. pp. 16812-16823. ISSN 1083-351X

J

Jacques, Richard O., Mills, Shirley C., Cazzonatto Zerwes, Paula, Fagade, Feyisope O., Green, John E., Downham, Scott, Sexton, Darren W. and Mueller, Anja (2015) Dynamin function is important for CC-chemokine receptor induced cell migration. Cell Biochemistry and Function, 33 (6). pp. 407-414. ISSN 0263-6484

K

Karsisiotis, Andreas Ioannis, Deacon, Oliver M., Rajagopal, Badri S., Macdonald, Colin, Blumenschein, Tharin M. A., Moore, Geoff and Worrall, Jonathan A. R. (2015) Backbone resonance assignments of ferric human cytochrome c and the pro-apoptotic G41S mutant in the ferric and ferrous states. Biomolecular NMR Assignments, 9 (2). pp. 415-419. ISSN 1874-2718

L

Lockwood, Colin W. J., Burlat, Benedicte, Cheesman, Myles R., Kern, Melanie, Simon, Jorg, Clarke, Thomas A., Richardson, David J. and Butt, Julea N. (2015) Resolution of key roles for the distal pocket histidine in cytochrome c nitrite reductases. Journal of the American Chemical Society, 137 (8). 3059–3068. ISSN 0002-7863

M

Marín, María J., Schofield, Claire L., Field, Robert A. and Russell, David A. (2015) Glyconanoparticles for colorimetric bioassays. Analyst, 140 (1). pp. 59-70.

O

O'Connell, Maria A. and Hayes, John D. (2015) The Keap1/Nrf2 pathway in health and disease: from the bench to the clinic. Biochemical Society Transactions, 43 (4). pp. 687-689. ISSN 0300-5127

Osborne, Andrew, Aldarwesh, Amal, Rhodes, Jeremy D., Broadway, David C., Everitt, Claire and Sanderson, Julie (2015) Hydrostatic pressure does not cause detectable changes to survival of human retinal ganglion. PLoS One, 10 (1). ISSN 1932-6203

P

Pfaffen, Stephanie, Bradley, Justin, Abdulqadir, Raz, Firme, Marlo R., Moore, Geoff, Le Brun, Nick and Murphy, Michael (2015) A diatom ferritin optimized for iron oxidation but not iron storage. The Journal of Biological Chemistry, 290. pp. 28416-28427. ISSN 1083-351X

S

Saura, Vanessa, Marin Altaba, Maria, Burguete, M. Isabel, Russell, David, Galindo, Francisco and Luis, Santiago V. (2015) Synthesis of new fluorescent bichromophoric compounds as ratiometric pH probes for intracellular measurements. Organic & Biomolecular Chemistry, 13 (28). pp. 7736-7749. ISSN 1477-0520

Stephenson, Michael, Howell, Lesley, O'Connell, Maria, Fox, Keith R., Adcock, Claire, Kingston, Jenny, Sheldrake, Helen, Pors, Klaus, Collingwood, Stephen P. and Searcey, Mark (2015) Solid-phase synthesis of duocarmycin analogues and the effect of C-terminal substitution on biological activity. The Journal of Organic Chemistry, 80 (19). 9454–9467. ISSN 0022-3263

Stokes, Leanne, Spencer, Sarah J. and Jenkins, Trisha A. (2015) Understanding the role of P2X7 in affective disorders—are glial cells the major players? Frontiers in Cellular Neuroscience, 9. ISSN 1662-5102

W

Wong, Steve, Grigg, Jason, Le Brun, Nick, Moore, Geoff, Murphy, Michael and Mauk, Grant (2015) The B-type channel is a major route for iron entry into the ferroxidase center and central cavity of bacterioferritin. The Journal of Biological Chemistry, 290 (6). pp. 3732-3739. ISSN 1083-351X