Items where Research Group is "Medicinal Chemistry

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Number of items: 18.

A

Angulo, Jesus ORCID: https://orcid.org/0000-0001-7250-5639, Goffin, Sarah, Gandhi, Daivik, Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949 and Howell, Lesley (2016) Unveiling the "three finger pharmacophore" required for p53-MDM2 inhibition by saturation transfer difference NMR initial growth rates approach. Chemistry - A European Journal, 22 (17). pp. 5858-5862. ISSN 0947-6539

Anwar, Awais, Gould, Emma, Tinson, Ryan, Groom, Murree and Hamilton, Chris J. (2016) Think Yellow and Keep Green—Role of Sulfanes from Garlic in Agriculture. Antioxidants, 6 (1). ISSN 2076-3921

B

Beekman, Andrew M. ORCID: https://orcid.org/0000-0002-3056-6406, O'Connell, Maria A. ORCID: https://orcid.org/0000-0002-0267-0951 and Howell, Lesley A. (2016) Identification of small-molecule inhibitors of the antiapoptotic protein myeloid cell leukaemia-1 (Mcl-1). ChemMedChem, 11 (8). 840–844. ISSN 1860-7179

Buffet, Kevin, Nierengarten, Iwona, Galanos, Nicolas, Gillon, Emilie, Holler, Michel, Imberty, Anne, Matthews, Susan E. ORCID: https://orcid.org/0000-0001-8821-0851, Vidal, Sébastien, Vincent, Stéphane P. and Nierengarten, Jean-François (2016) Pillar[5]arene-based glycoclusters: synthesis and multivalent binding to pathogenic bacterial lectins. Chemistry - A European Journal, 22 (9). pp. 2955-2963. ISSN 0947-6539

Busnelli, Marta, Kleinau, Gunnar, Muttenthaler, Markus, Stoev, Stoytcho, Manning, Maurice, Bibic, Lucka, Howell, Lesley A., McCormick, Peter J., Di Lascio, Simona, Braida, Daniela, Sala, Mariaelvina, Rovati, G. Enrico, Bellini, Tommaso and Chini, Bice (2016) Design and characterization of superpotent bivalent ligands targeting oxytocin receptor dimers via a channel-like structure. Journal of Medicinal Chemistry, 59 (15). 7152–7166. ISSN 0022-2623

C

Cominetti, Marco M. D., Hughes, David L. and Matthews, Susan E. ORCID: https://orcid.org/0000-0001-8821-0851 (2016) Open-resorcinarenes, a new family of multivalent scaffolds. Organic & Biomolecular Chemistry, 14 (43). pp. 10161-10164. ISSN 1477-0520

D

Davidson, Sean M., Foote, Kirsty, Kunuthur, Suma, Gosain, Raj, Tan, Noah, Tyser, Richard, Zhao, Yong Juan, Graeff, Richard, Ganesan, A. ORCID: https://orcid.org/0000-0003-4862-7999, Duchen, Michael R., Patel, Sandip and Yellon, Derek M. (2016) Inhibition of NAADP signalling on reperfusion protects the heart by preventing lethal calcium oscillations via two-pore channel 1 and opening of the mitochondrial permeability transition pore. Cardiovascular Research, 108 (3). pp. 357-366. ISSN 0008-6363

de Lera, Angel R. and Ganesan, A. ORCID: https://orcid.org/0000-0003-4862-7999 (2016) Epigenetic polypharmacology: from combination therapy to multitargeted drugs. Clinical Epigenetics, 8. ISSN 1868-7075

G

Galanos, Nicolas, Gillon, Emilie, Imberty, Anne, Matthews, Susan ORCID: https://orcid.org/0000-0001-8821-0851 and Vidal, Sebastien (2016) Pentavalent pillar[5]arene-based glycoclusters and their multivalent binding to pathogenic bacterial lectins. Organic & Biomolecular Chemistry, 14. pp. 3476-3481. ISSN 1477-0520

Ganesan, A. ORCID: https://orcid.org/0000-0003-4862-7999 (2016) Multitarget drugs: an epigenetic epiphany. ChemMedChem, 11 (12). pp. 1227-1241. ISSN 1860-7179

H

Howell, Lesley and Beekman, Andrew ORCID: https://orcid.org/0000-0002-3056-6406 (2016) Small molecule and peptide inhibitors of the pro-survival protein Mcl-1. ChemMedChem, 11 (8). 802–813. ISSN 1860-7179

L

Lall, Namrita, Kumar, Vivek, Meyer, Debra, Gasa, Nomasomi, Hamilton, Chris, Matsabisa, Motlalepula and Oosthuizen, Carel (2016) In vitro and In vivo antimycobacterial, hepatoprotective and immunomodulatory activity of Euclea natalensis and its mode of action. Journal of Ethnopharmacology, 194. 740–748. ISSN 0378-8741

M

Matthews, Susan E. ORCID: https://orcid.org/0000-0001-8821-0851 (2016) Calixsugars: Finally Reaching Their Therapeutic Potential? In: Calixarenes and Beyond. Springer, pp. 559-600. ISBN 978-3-319-31865-3

S

Santos, Gabriela B., Ganesan, A. ORCID: https://orcid.org/0000-0003-4862-7999 and Emery, Flavio S. (2016) Oral administration of peptide-based drugs: Beyond Lipinski's rule. ChemMedChem, 11 (20). 2245–2251. ISSN 1860-7179

Shaheen, Farzana, Jabeen, Almas, Ashraf, Samreen, Nadeem-ul-Haque, Muhammad, Ali Shah, Zafar, Asad Ziaee, Muhammad, Dastagir, Nida and Ganesan, A. ORCID: https://orcid.org/0000-0003-4862-7999 (2016) Total synthesis, structural, and biological evaluation of stylissatin A and related analogs. Journal of Peptide Science, 22 (9). pp. 607-617. ISSN 1075-2617

Silva Júnior, P. E., Rezende, L. C D, Gimenes, Julia Possamai, Maltarollo, Vinícius Goncąlves, Dale, James, Trossini, G. H G, Emery, F. S. and Ganesan, A. ORCID: https://orcid.org/0000-0003-4862-7999 (2016) Synthesis of two 'heteroaromatic rings of the future' for applications in medicinal chemistry. RSC Advances, 6 (27). pp. 22777-22780. ISSN 2046-2069

W

Waller, Zoë A. E., Pinchbeck, Benjamin J., Buguth, Bhovina Seewoodharry, Meadows, Timothy G., Richardson, David J. ORCID: https://orcid.org/0000-0002-6847-1832 and Gates, Andrew J. ORCID: https://orcid.org/0000-0002-4594-5038 (2016) Control of bacterial nitrate assimilation by stabilization of G-quadruplex DNA. Chemical Communications, 52 (92). pp. 13511-13514. ISSN 1359-7345

Wright, Elisé P., Day, Henry A., Ibrahim, Ali M., Kumar, Jeethendra, Boswell, Leo J. E., Huguin, Camille, Stevenson, Clare E. M., Pors, Klaus and Waller, Zoë A. E. (2016) Mitoxantrone and analogues bind and stabilize i-motif forming DNA sequences. Scientific Reports, 6. ISSN 2045-2322

This list was generated on Sat Feb 4 12:26:46 2023 UTC.