Synthesis of two 'heteroaromatic rings of the future' for applications in medicinal chemistry

Silva Júnior, P. E., Rezende, L. C D, Gimenes, Julia Possamai, Maltarollo, Vinícius Goncąlves, Dale, James, Trossini, G. H G, Emery, F. S. and Ganesan, A. (2016) Synthesis of two 'heteroaromatic rings of the future' for applications in medicinal chemistry. RSC Advances, 6 (27). pp. 22777-22780. ISSN 2046-2069

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Abstract

In a computational study, the 1H-pyrazolo[3,4-c]pyridin-5-ol and 2,6-naphthyridin-3-ol heterocycles were identified as unknown heteroaromatic ring systems of potential value for medicinal chemistry. Here we report robust and concise synthetic protocols that provide access to these two scaffolds on a multigram scale.

Item Type: Article
Faculty \ School: Faculty of Science > School of Pharmacy
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Depositing User: Pure Connector
Date Deposited: 09 May 2016 15:00
Last Modified: 22 Apr 2020 01:17
URI: https://ueaeprints.uea.ac.uk/id/eprint/58601
DOI: 10.1039/c6ra01099g

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