Items where Research Group is "Chemical Biology and Medicinal Chemistry (former - to 2021)

A

Abdelhamid, Mahmoud A. S., Gates, Andrew J. ORCID: https://orcid.org/0000-0002-4594-5038 and Waller, Zoë A. E. (2019) Destabilization of i-motif DNA at neutral pH by G-quadruplex ligands. Biochemistry, 58 (4). 245–249. ISSN 0006-2960

Aldholmi, Mohammed, Marchand, Pascal, Ourliac-Garnier, Isabelle, Le Pape, Patrice and Ganesan, A. ORCID: https://orcid.org/0000-0003-4862-7999 (2019) A decade of antifungal leads from natural products: 2010-2019. Pharmaceuticals, 12 (4). ISSN 1424-8247

Arbach, Miriam, Santana, Taris M., Moxham, Hazel, Tinson, Ryan, Anwar, Awais, Groom, Murree and Hamilton, Christopher (2019) Antimicrobial garlic-derived diallyl polysulfanes: Interactions with biological thiols in Bacillus subtilis. Biochimica et Biophysica Acta - General Subjects, 1863 (6). pp. 1050-1058. ISSN 0304-4165

B

Beekman, Andrew ORCID: https://orcid.org/0000-0002-3056-6406, Cominetti, Marco, Cartwright, Oliver, Boger, Dale L. and Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949 (2019) A small molecule drug conjugate (SMDC) of DUPA and a duocarmycin built on the solid phase. MedChemComm, 10 (12). pp. 2170-2174. ISSN 2040-2503

Beekman, Andrew ORCID: https://orcid.org/0000-0002-3056-6406, Cominetti, Marco M D and Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949 (2019) Duocarmycins as Antibody–Drug Conjugate (ADC) Payloads. In: Cytotoxic Payloads for Antibody-Drug Conjugates. Royal Society of Chemistry. ISBN 978-1-78801-077-1

Beekman, Andrew M. ORCID: https://orcid.org/0000-0002-3056-6406, Cominetti, Marco M. D., Walpole, Samuel J., Prabhu, Saurabh, O'Connell, Maria A. ORCID: https://orcid.org/0000-0002-0267-0951, Angulo Alvarez, Jesus ORCID: https://orcid.org/0000-0001-7250-5639 and Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949 (2019) Identification of selective protein-protein interaction inhibitors using efficient in silico peptide-directed ligand design. Chemical Science, 10 (16). pp. 4502-4508. ISSN 2041-6520

C

Carro, Laura (2019) Recent progress in the development of small-molecule FtsZ inhibitors as chemical tools for the development of novel antibiotics. Antibiotics, 8 (4). ISSN 2079-6382

Chi, Bui Khanh, Huyen, Nguyen Thi Thu, Loi, Vu Van, Gruhlke, Martin, Schaffer, Marc, Mäder, Ulrike, Maaß, Sandra, Becher, Dorte, Bernhardt, Jorg, Arbach, Miriam, Hamilton, Chris J., Slusarenko, Alan J. and Antelmann, Haike (2019) The disulfide stress response and protein S-thioallylation caused by allicin and diallyl polysulfanes in Bacillus subtilis as revealed by transcriptomics and proteomics. Antioxidants, 8 (12). ISSN 2076-3921

G

Ganesan, A. ORCID: https://orcid.org/0000-0003-4862-7999, Arimondo, Paola B., Rots, Marianne G., Jeronimo, Carmen and Berdasco, Mariá (2019) The timeline of epigenetic drug discovery:From reality to dreams. Clinical Epigenetics, 11 (1). ISSN 1868-7075

K

Kay, Kristine L., Hamilton, Chris J. and Le Brun, Nick E. ORCID: https://orcid.org/0000-0001-9780-4061 (2019) Mass spectrometric studies of Cu(I)-binding to the N-terminal domains of B. subtilis CopA and influence of bacillithiol. Journal of Inorganic Biochemistry, 190. pp. 24-30. ISSN 0162-0134

L

Linzner, Nico, Loi, Vu Van, Fritsch, Verena Nadin, Tung, Quach Ngoc, Stenzel, Saskia, Wirtz, Markus, Hell, Rüdiger, Hamilton, Chris J., Tedin, Karsten, Fulde, Marcus and Antelmann, Haike (2019) Staphylococcus aureus uses the Bacilliredoxin (BrxAB)/Bacillithiol Disulfide reductase (YpdA) redox pathway to defend against oxidative stress under infections. Frontiers in Microbiology, 10. ISSN 1664-302X

R

Ruzic, Dusan, Petkovic, Milos, Agbaba, Danica, Ganesan, A. ORCID: https://orcid.org/0000-0003-4862-7999 and Nikolic, Katarina (2019) Combined ligand and fragment-based drug design of selective histone deacetylase – 6 inhibitors. Molecular Informatics, 38 (5). ISSN 1868-1743

Z

Zhang, Yueying, Yang, Minglei, Duncan, Susan, Yang, Xiaofei, Abdelhamid, Mahmoud, Huang, Lin, Zhang, Huakun, Benfey, Philip N, Waller, Zoe and Ding, Yiliang (2019) G-quadruplex structures trigger RNA phase separation. Nucleic Acids Research, 47 (22). 11746–11754. ISSN 0305-1048